2022 GMC Sierra 2500 HD Cooling and Climate Controls
Find Your Specific 2022 GMC Sierra 2500 HD Cooling and Climate Controls
Below you will find various in-demand GMC Cooling and Climate Controls, components and accessories for your 2022 Sierra 2500 HD. Advance Auto Parts has popular Sierra 2500 HD parts like Air Conditioning Parts, Engine Cooling Parts, Blower Motor and Related Products and more. You’ll also find aftermarket and OEM Cooling and Climate Controls for other Sierra 2500 HD model years including
2014,
2015,
2016,
2017,
2018,
2019,
2020,
2021,
2023 and more. Select a category of 2022 GMC Sierra 2500 HD Cooling and Climate Controls below and start saving instantly.
Popular 2022 GMC Sierra 2500 HD Cooling and Climate Controls Categories
Essential Cooling and Climate Controls for 2022 GMC Sierra 2500 HDs
Carquest Premium – A/C New; w/ Clutch; w/ HT6 Compressor (Part No.T88931)
from
$349.99
Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.
Product Features:
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Product Features:
- Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
- New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
- The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
- All new compressors must pass a helium leak test and pump up function test prior to packaging.
- O-Rings and gaskets necessary for installation are included.
- O-Rings and gaskets necessary for installation are included.
Dorman – Coolant Housing/Water Outlet: With Water Outlet, 90 Degree Neck Angle (Part No.902-2127)
from
$111.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.
Product Features:
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Product Features:
- Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models.
- Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking.
- Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
- Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
ACDelco – GM Original Equipment Engine Cooling Fan Clutch (Part No.G5010446142ACD)
from
$527.76
ACDelco GM Original Equipment Engine Cooling Fan Clutches control the speed of the radiator fan based on the temperature of the air after it passes through the radiator fins. This original equipment engine cooling fan clutch is a GM-recommended replacement for your vehicle’s original components and has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
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Product Features:
- Quiets noisy cooling fans with stuck fan clutches, restores fuel economy
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
ACDelco – GM Original Equipment Engine Coolant Thermostat (Part No.G4000310418ACD)
from
$81.39
An ACDelco GM Original Equipment Engine Coolant Thermostat is a temperature controlled valve located in the engine coolant outlet to, or the inlet from, the radiator, and is a GM-recommended replacement for your vehicle’s original component. It controls the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature. This original equipment engine coolant thermostat has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
Product Features:
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Product Features:
- Control the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Felpro – Engine Coolant Thermostat Housing Seal (Part No.35720)
from
$4.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered and manufactured specifically for the repair environment
- Unsurpassed quality you can trust
- Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
Carquest Premium – Engine Coolant Water Outlet (Part No.85083)
from
$23.79
Direct-fit replacement for ease of installation
Product Features:
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Product Features:
- Meets and/or exceeds OEM standard
- Direct-fit replacement for ease of installation
- 100% leak tested
- Meets and/or exceeds OEM standard
- 100% leak tested
- Direct-fit replacement for ease of installation
ACDelco – GM Original Equipment Oil Cooler Seal (Part No.A6310320812ACD)
from
$45.26
The ACDelco GM Original Equipment Engine Oil Cooler Seal is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.
Product Features:
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Product Features:
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Dorman – A/C Service Valve Cap (Part No.902-025)
from
$8.99
This A/C service valve cap is designed to match the fit and function of the original cap on specified applications, and is engineered for reliable performance and durability.
Product Features:
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Product Features:
- Direct replacement – this A/C service valve cap is designed to match the fit and function of the original cap on specified applications.
- Restores functionality – reliable replacement for an original part that is leaking or has failed due to fatigue.
- Durable construction – this part is made from quality materials to ensure reliable performance and long service life
- Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)
from
$10.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Repair leaking A/C system, restore A/C function
- Helps restore A/C Function
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
- GM regularly updates production and service part designs to integrate new materials and technologies
Carquest – A/C Auto Temperature Control Relay (Part No.R3107)
from
$18.99
Product Features:
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- Our units are all pre-aligned & pre-adjusted to save installation time and ensure proper switching.
- A lubricated felt pad that lubricates the cam lobes on the vehicles distributor. This reduces wear on the point set rubbing block, extending the usable life of the part.
- Ventilated where available, tungsten contacts, which run cooler and exhibit less erosion.
- The copper-alloy shunt provides superior resistance to breakage, due to the flexing of the moving arm on the point set. It also significantly increases current conductivity over typical steel, shunts.
GM Genuine Parts – Multi-Purpose Relay (Part No.15016745)
from
$49.49
GM Genuine Parts Wiring Relays are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These relays help connect or disconnect power to a vehicle accessory when it receives a low voltage signal from a switch. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Helps connect or disconnect power to vehicle accessories
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Carquest Premium – Temperature Sender With Gauge and Harness (Part No.WTC1035)
from
$31.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
Product Features:
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Product Features:
- 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
- Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
- Brass sensor housing precision machined to meet or exceed OE thermal conductivity
- OE precision matched thermistor position for correct output parameters
- Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
ACDelco – Engine Coolant Temperature Sensor (Part No.213-4333)
from
$42.99
ACDelco GM Original Equipment Engine Coolant Temperature Sensors monitor engine temperature, and are GM-recommended replacements for your vehicle’s original components. The engine temperature signal is used by the engine control module to adjust the air/fuel mixture and ignition timing. These original equipment engine coolant temperature sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
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Product Features:
- Helps keep engine running at proper temperature
- Alerts vehicle operator of high engine temperature conditions
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Felpro – Engine Water Pump Gasket (Part No.35664)
from
$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design
- Manufactured for the sealing repair environment
- Validated for fit, form, and function
- Quality that you can trust
Mahle – Water Pump Gasket (Part No.G3040310278MAH)
from
$6.65
Water Pump Gasket
Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54218)
from
$13.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.
Product Features:
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Product Features:
- Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap.
- Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
- Seamless fit – reverse-engineered from the original equipment to fit perfectly
- Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
ACDelco – GM Original Equipment Expansion Tank Cap (Part No.G1040206092ACD)
from
$26.68
An ACDelco GM Original Equipment Expansion Tank Cap is a spring loaded cap that seals the radiator filler neck or surge tank, and is a GM-recommended replacement for your vehicle’s original component. It maintains pressure on the cooling system while the engine is operating, which raises the boiling point of the engine coolant. It also replenishes the system with coolant from the expansion tank (if equipped) when the engine cools off. This original equipment radiator cap has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors. Get the GM quality you know and trust with ACDelco GM Original Equipment Thermostats and Caps. Stay with the brand of parts your General Motors vehicle came with and get peace of mind that the fit, form, and function is up to the high standards and specifications of General Motors. ACDelco GM Original Equipment Thermostats and Caps are engineered for virtually every model of GM car, light duty truck, and sport utility vehicle.
Product Features:
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Product Features:
- Seal and maintain pressure on the cooling system for vehicle safety
- Raise the boiling point of the engine coolant to maintain efficiency
- Fit most models of GM vehicles for expanded coverage
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
ACDelco – A/C Service Valve (Part No.R1129947779ACD)
from
$13.13
A/C Service Valve
GM Genuine Parts – Air Conditioning Compressor Relief Valve (Part No.15-5711)
from
$67.99
GM Genuine Parts A/C Compressor Relief Valves are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
- GM regularly updates production and service part designs to integrate new materials and technologies
Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-514)
from
$92.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
Product Features:
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Product Features:
- Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade.
- Quality construction – manufactured from premium materials for a long service life.
- Excellent value – original equipment quality at a lower price
- Quality tested – has undergone testing to ensure proper fit and performance
Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-104)
from
$61.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
Product Features:
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Product Features:
- Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade.
- Quality construction – manufactured from premium materials for a long service life.
- Excellent value – original equipment quality at a lower price
- Quality tested – has undergone testing to ensure proper fit and performance
Autopart International Inc – Expansion Tank Cap (Part No.G10402009531API)
from
$12.81
Expansion Tank Cap
ACDelco – GM Original Equipment Expansion Tank Cap (Part No.G1040465619ACD)
from
$21.02
An ACDelco GM Original Equipment Expansion Tank Cap is a spring loaded cap that seals the radiator filler neck or surge tank, and is a GM-recommended replacement for your vehicle’s original component. It maintains pressure on the cooling system while the engine is operating, which raises the boiling point of the engine coolant. It also replenishes the system with coolant from the expansion tank (if equipped) when the engine cools off. This original equipment radiator cap has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors. Get the GM quality you know and trust with ACDelco GM Original Equipment Thermostats and Caps. Stay with the brand of parts your General Motors vehicle came with and get peace of mind that the fit, form, and function is up to the high standards and specifications of General Motors. ACDelco GM Original Equipment Thermostats and Caps are engineered for virtually every model of GM car, light duty truck, and sport utility vehicle.
Product Features:
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Product Features:
- Seal and maintain pressure on the cooling system for vehicle safety
- Raise the boiling point of the engine coolant to maintain efficiency
- Fit most models of GM vehicles for expanded coverage
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
GM Genuine Parts – Water Inlet Seal (Part No.12587397)
from
$8.99
GM Genuine Parts Engine Coolant Thermostat Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help close and prevent coolant from leaking out of your vehicle’s cooling system components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Helps close and prevent coolant from leaking out of your vehicle’s cooling system components to maintain the proper engine temperature
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Carquest Premium – Blower Motor: With Wheel (Part No.75843)
from
$98.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.
Product Features:
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Product Features:
- Meets or exceeds OE design and performance
- Magnetic size and properties compare or exceed OEM
- Windings meet or exceed OEM specifications
- Motor RPM equivalent to or exceeds OEM motor
Carquest Premium – Blower Motor: With Wheel (Part No.75039)
from
$168.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.
Product Features:
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Product Features:
- Meets or exceeds OE design and performance
- Magnetic size and properties compare or exceed OEM
- Windings meet or exceed OEM specifications
- Motor RPM equivalent to or exceeds OEM motor
Carquest Premium – Blower Motor: With Wheel (Part No.75865)
from
$109.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.
Product Features:
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Product Features:
- Meets or exceeds OE design and performance
- Magnetic size and properties compare or exceed OEM
- Windings meet or exceed OEM specifications
- Motor RPM equivalent to or exceeds OEM motor
Carquest Premium – Blower Motor: Without Wheel (Part No.35062)
from
$59.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.
Product Features:
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Product Features:
- Meets or exceeds OE design and performance
- Magnetic size and properties compare or exceed OEM
- Windings meet or exceed OEM specifications
- Motor RPM equivalent to or exceeds OEM motor
Upgrade your 2022 GMC Sierra 2500 HD with Top-Quality Cooling and Climate Controls
When it comes to maintaining or upgrading your 2022 GMC Sierra 2500 HD, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Cooling and Climate Controls are key to keeping your Sierra 2500 HD functioning at its best. At Advance Auto Parts, we offer a wide selection of 28 Cooling and Climate Controls for the 2022 GMC Sierra 2500 HD, designed to meet your needs without breaking the bank.
From
Air Conditioning Part
replacements to
Engine Cooling Parts
upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.
Affordable Prices and Wide Selection
Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2022 GMC Sierra 2500 HD at great prices.
Our Cooling and Climate Controls inventory for this model
ranges from just $4.85 to $363.02, with
an average price of $52.68.
Our 28 Cooling and Climate Controls in stock come from 9 trusted brands, so you’re sure to find the right part for your 2022 GMC Sierra 2500 HD without overspending.
Top Brands and High Customer Satisfaction
Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2022 GMC Sierra 2500 HD, we stock popular OEM and aftermarket Cooling and Climate Controls from top names
like Carquest Premium, Motorad, Dorman, and more.
Carquest Premium Cooling and Climate Controls
start at just $10.99 and boast an impressive 4 stars average rating from customers.
Motorad and Dorman also bring quality to the table, with Cooling and Climate Controls available starting at $13.99, and at an average 4 stars rating.
With 231 customer reviews and counting, our 2022 GMC Sierra 2500 HD Cooling and Climate Controls have a strong track record of reliability, ensuring you can trust your purchase.
Explore Related Parts and More
While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants
and more to make sure your 2022 GMC Sierra 2500 HD is always ready to roll. We’re committed to providing you with everything you need to keep your Sierra 2500 HD in top shape, all in one place.
Start shopping confidently below for your 2022 GMC Sierra 2500 HD!
Best-Selling Air Conditioning Parts for 2022 GMC Sierra 2500 HDs
Enhance the driving experience in your GMC with 6 quality Air Conditioning Part components, starting at $10.99.
GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)
from
$10.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
See More
Product Features:
- Repair leaking A/C system, restore A/C function
- Helps restore A/C Function
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
- GM regularly updates production and service part designs to integrate new materials and technologies
Autopart International Inc – A/C Compressor (Part No.R10003199103API)
from
$363.02
A/C Compressor
Carquest Premium – New, with Clutch, with 7SAS17A Compressor (Part No.T168343)
from
$284.99
Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.
Product Features:
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Product Features:
- Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
- New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
- The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
- All new compressors must pass a helium leak test and pump up function test prior to packaging.
- O-Rings and gaskets necessary for installation are included.
ACDelco – Relay (Part No.P2020765633ACD)
from
$16.19
Relay
GM Genuine Parts – Air Conditioning Line O-Ring (Part No.13579649)
from
$15.99
GM Genuine Parts Rubber-Bonded Sealing Washers are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
See More
Product Features:
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
- GM regularly updates production and service part designs to integrate new materials and technologies
ACDelco – A/C Service Valve (Part No.R1129947779ACD)
from
$13.13
A/C Service Valve
Most Popular 2022 GMC Sierra 2500 HD Engine Cooling Parts
Customize your GMC with 21 Engine Cooling Parts products
like Thermostats,
Radiator Caps, and
Water Pump Gaskets, all
priced under $128.99.
Motorad – Standard Thermostat: With Seals, 180, 185 Degrees (Part No.447448)
from
$40.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54218)
from
$13.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.
Product Features:
See More
Product Features:
- Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap.
- Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
- Seamless fit – reverse-engineered from the original equipment to fit perfectly
- Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
ACDelco – GM Original Equipment Engine Coolant Thermostat (Part No.G4000310418ACD)
from
$81.39
An ACDelco GM Original Equipment Engine Coolant Thermostat is a temperature controlled valve located in the engine coolant outlet to, or the inlet from, the radiator, and is a GM-recommended replacement for your vehicle’s original component. It controls the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature. This original equipment engine coolant thermostat has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
Product Features:
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Product Features:
- Control the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Carquest Premium – Standard Thermostat: With Seal, 185 Degrees (Part No.14728)
from
$43.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: With Seal, 180 Degrees (Part No.14738)
from
$42.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: With Seal, 187 Degrees (Part No.15158)
from
$38.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54218CD)
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$16.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.
Product Features:
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Product Features:
- Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap.
- Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
- Seamless fit – reverse-engineered from the original equipment to fit perfectly
- Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
ACDelco – GM Original Equipment Expansion Tank Cap (Part No.G1040465619ACD)
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$21.02
An ACDelco GM Original Equipment Expansion Tank Cap is a spring loaded cap that seals the radiator filler neck or surge tank, and is a GM-recommended replacement for your vehicle’s original component. It maintains pressure on the cooling system while the engine is operating, which raises the boiling point of the engine coolant. It also replenishes the system with coolant from the expansion tank (if equipped) when the engine cools off. This original equipment radiator cap has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors. Get the GM quality you know and trust with ACDelco GM Original Equipment Thermostats and Caps. Stay with the brand of parts your General Motors vehicle came with and get peace of mind that the fit, form, and function is up to the high standards and specifications of General Motors. ACDelco GM Original Equipment Thermostats and Caps are engineered for virtually every model of GM car, light duty truck, and sport utility vehicle.
Product Features:
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Product Features:
- Seal and maintain pressure on the cooling system for vehicle safety
- Raise the boiling point of the engine coolant to maintain efficiency
- Fit most models of GM vehicles for expanded coverage
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Carquest Premium – Coolant Housing/Water Outlet (Part No.85945)
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$20.99
We are proud to offer this CARQUEST product line: CARQUEST Water Outlets. Our products are engineered and tested to provide years of trouble free operation and designed to be hassle free OE replacement part that meets and/or exceeds OE standards. Backed by over 50 years of mobile temperature control experience, fix it once and fix it right with CARQUST Water Outlets and Thermostat Housings.
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Product Features:
- Meets and/or exceeds OEM standard
- Includes quality gasket or O-ring to ensure proper seal (where applicable)
- 100% leak tested
- Direct-fit replacement for ease of installation
Felpro – Engine Water Pump Gasket (Part No.36110)
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$7.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design
- Manufactured for the sealing repair environment
- Validated for fit, form, and function
- Quality that you can trust
Mahle – Engine Coolant Thermostat O-Ring (Part No.G4030310258MAH)
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$7.41
The Mahle Engine Coolant Thermostat O-Ring is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.
Product Features:
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Product Features:
- Seals the thermostat housing and helps prevent coolant from leaking from the engine for proper engine temperature
- Premium Original Equipment replacement
- Provides performance and dependability
- Manufactured to meet OE specifications
Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-111)
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$112.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
Product Features:
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Product Features:
- Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade.
- Quality construction – manufactured from premium materials for a long service life.
- Excellent value – original equipment quality at a lower price
- Quality tested – has undergone testing to ensure proper fit and performance
ACDelco – GM Original Equipment Oil Cooler Seal (Part No.A6310320812ACD)
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$45.26
The ACDelco GM Original Equipment Engine Oil Cooler Seal is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.
Product Features:
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Product Features:
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Carquest Premium – Reverse Rotation Severe Duty Thermal Fan Clutch (Part No.46145)
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$128.99
Product Features:
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- Designed, tested, and built by application
- OE performance, fit, and appearance
- Precision machined
- Out of box installation
ACDelco – 15-10595 GM Original Equipment Engine Coolant Water Outlet (Part No.G4010349243ACD)
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$18.46
ACDelco GM Original Equipment Engine Coolant Water Outlets are housings that connect the radiator hoses to the engine, typically housing the engine coolant thermostat. For certain applications, the water outlet contains threaded holes or ports for sensors and switches. These original equipment engine coolant water outlets are GM-recommended replacements for your vehicle’s original components and have been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
Product Features:
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Product Features:
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Worldpac – THERMOSTAT HOUSING (Part No.G40101697790DOR)
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$16.28
THERMOSTAT HOUSING
Autopart International Inc – Expansion Tank Cap (Part No.G10402009531API)
from
$12.81
Expansion Tank Cap
Carquest Premium – Coolant Temperature Sensor (Part No.WTC1276)
from
$10.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
Product Features:
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Product Features:
- 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
- Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
- Brass sensor housing precision machined to meet or exceed OE thermal conductivity
- OE precision matched thermistor position for correct output parameters
- Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
ACDelco – 12587397 GM Original Equipment Engine Coolant Water Inlet Seal (Part No.G4030310258ACD)
from
$10.84
An ACDelco GM Original Equipment Engine Coolant Water Inlet Seal is a GM-recommended replacement for your vehicle’s original component. It seals and helps prevent coolant from leaking out of cooling system components. This original equipment engine coolant water inlet seal has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
Product Features:
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Product Features:
- Seals and helps prevent coolant from leaking out of cooling system components to maintain the proper engine temperature
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
GM Genuine Parts – Water Inlet Seal (Part No.12587397)
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$8.99
GM Genuine Parts Engine Coolant Thermostat Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help close and prevent coolant from leaking out of your vehicle’s cooling system components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Helps close and prevent coolant from leaking out of your vehicle’s cooling system components to maintain the proper engine temperature
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Mahle – Thermostat Housing G (Part No.G40202287153MAH)
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$4.85
Thermostat Housing G
Top Picks for 2022 GMC Sierra 2500 HD Blower Motor and Related Products
Upgrade GMC Sierra 2500 HDs with top-quality Blower Motor and Related Products parts, including 1 OEM and aftermarket selections for your 2022 model.
Carquest Premium – Blower Motor: With Wheel (Part No.75158)
from
$266.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.
Product Features:
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Product Features:
- Meets or exceeds OE design and performance
- Magnetic size and properties compare or exceed OEM
- Windings meet or exceed OEM specifications
- Motor RPM equivalent to or exceeds OEM motor
- Meets or exceeds OE design and performance
- Magnetic size and properties compare or exceed OEM
- Windings meet or exceed OEM specifications
- Motor RPM equivalent to or exceeds OEM motor
Top-Rated Cooling and Climate Controls Brands For Your 2022 GMC Sierra 2500 HD
Shop for the best-rated brands offering Cooling and Climate Controls and other products for your 2022 GMC Sierra 2500 HDs. Below you’ll find some of our best rated Cooling and Climate Controls from Carquest Premium, Motorad, and Dorman, and more. Cooling and Climate Controls from these brands that fit a 2022 Sierra 2500 HD start at just $10.99 and are rated as high as 4 stars. OEM and aftermarket Cooling and Climate Controls don’t get more top quality, durable, and affordable than from the brands below.
Popular Carquest Premium 2022 GMC Sierra 2500 HD Cooling and Climate Controls
When it comes to maintaining or upgrading your 2022 GMC Sierra 2500 HD, using quality Cooling and Climate Controls is essential to ensure durability and a perfect fit. Carquest Premium ticks all of those boxes. We offer a wide selection of Carquest Premium Cooling and Climate Controls, specifically designed for the 2022 GMC Sierra 2500 HD. With over 8 Carquest Premium brand Cooling and Climate Controls in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $10.99, with an average price of just $104.87. Plus, with over 59 customer reviews and an average rating of 4 stars, you can trust that our Carquest Premium Cooling and Climate Controls will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
Popular Motorad 2022 GMC Sierra 2500 HD Cooling and Climate Controls
Motorad auto parts is one of the highest quality Cooling and Climate Control brands in the market. Any 2022 GMC Sierra 2500 HD owner should feel confident when installing genuine Motorad parts in their vehicle. To ensure the best fit and performance for your 2022 Sierra 2500 HD, Advance Auto Parts carries a full inventory of 1 Motorad Cooling and Climate Controls. Plus you will be keeping your GMC in peak condition while saving money because prices on these Motorad Cooling and Climate Controls range up to $40.99, plus, with more than 3 customer reviews and an impressive 4 stars average rating, you can be confident the Fram Cooling and Climate Controls below will deliver on both quality and value.
from
$40.99
$40.99
(3)
Standard Thermostat: With Seals, 180, 185 Degrees
“Product was correct! Repair went well”
FAQs for 2022 GMC Sierra 2500 HD Cooling and Climate Controls
Which Cooling and Climate Controls are best-sellers for 2022 GMC Sierra 2500 HDs?
Out of 28 Cooling and Climate Controls that fit 2022 GMC Sierra 2500 HDs, the following parts are the top sellers:
- Standard Thermostat: With Seals, 180, 185 Degrees (11921768) – $40.99
- Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (11871344) – $16.99
- Air Conditioning System Valve Core (15730161) – $10.99
What’s the price range for 2022 GMC Sierra 2500 HD Cooling and Climate Controls?
Cooling and Climate Control prices for the 2022 GMC Sierra 2500 HD start at $4.85 and go up to $363.02 for the most premium parts.
What’s the average price of a Cooling and Climate Control for a 2022 GMC Sierra 2500 HD?
The average price for Cooling and Climate Controls for the 2022 GMC Sierra 2500 HD is $52.68. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Cooling and Climate Controls for other GMC Sierra 2500 HD model years?
What are the cheapest Cooling and Climate Controls for my 2022 GMC Sierra 2500 HD?
The cheapest 2022 GMC Sierra 2500 HD Cooling and Climate Controls we carry in stock are:
- Thermostat Housing G (12591621) – $4.85
- Engine Coolant Thermostat O-Ring (11999727) – $7.41
- Engine Water Pump Gasket (12084482) – $7.49
- Water Inlet Seal (12044502) – $8.99
- 12587397 GM Original Equipment Engine Coolant Water Inlet Seal (10748038) – $10.84
What are the top-rated Cooling and Climate Controls that fit the 2022 GMC Sierra 2500 HD?
Out of 231 reviews by customers, our 2022 GMC Sierra 2500 HD Cooling and Climate Controls have an average customer rating of . These are some of the highest-rated Cooling and Climate Control types for the 2022 GMC Sierra 2500 HD and their top-rated products:
- Engine Cooling Parts
- Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (11153255) – $13.99
- GM Original Equipment Engine Coolant Thermostat (11478680) – $81.39
- Standard Thermostat: With Seals, 180, 185 Degrees (11921768) – $40.99
- Air Conditioning Parts
- Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (11153255) – $13.99
- GM Original Equipment Engine Coolant Thermostat (11478680) – $81.39
- Standard Thermostat: With Seals, 180, 185 Degrees (11921768) – $40.99
What types of Cooling and Climate Controls do you sell for my 2022 GMC Sierra 2500 HD?
As of 2/5/25, these are some of the most in-demand types of Cooling and Climate Controls for a 2022 GMC Sierra 2500 HD:
Can I get help with 2022 GMC Sierra 2500 HD Cooling and Climate Control orders?
Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Cooling and Climate Controls and more.
What is your return policy for GMC Sierra 2500 HD Cooling and Climate Controls?
Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.
