Essential Engine Parts for 2022 Chevrolet Express 4500s

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$203.99

Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:

DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road

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$26.99

Product Features:

DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road

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$0.99

Engine Oil Dipstick Tube O-Ring

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$6.99

Product Features:

Superior Wear Protection – Formulated with extreme pressure additives to protect engine components from metal-to-metal contact during initial startup
High Tackiness – Stays in place during assembly and storage, ensuring consistent lubrication exactly where it’s needed
Broad Compatibility – Safe for use with all engine components including camshafts, lifters, bearings, and valve train parts
Easy Startup Support – Reduces friction and prevents dry starts by providing instant lubrication during first engine fire-up

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$10.49

Sealed Power® parts provide innovative designs, use leading edge materials and utilize ISO & QS certified manufacturing in order to deliver top quality products that meet the rigorous demands of today’s modern engines.

Product Features:

Formulated for prelubrication cam lobes, lifters & engine bearings
Increases load carrying capacity
Holds fast to surfaces
Exacting tolerances
Meets or exceeds OEM specifications
4.0 oz. Squeeze Container

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$71.99

ACDelco GM Original Equipment Multi Purpose Sensors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.

Product Features:

Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional
ACDelco GM Original Equipment parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
GM regularly updates production and service part designs to integrate new materials and technologies

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$51.99

Building upon a foundation of premium full-line products established under NGK ignition and oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. is the only OE supplier with a full line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:

NTK’s Manifold Absolute Pressure Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function to ensure proper manifold pressure, fuel metering and ignition timing.
The Manifold Absolute Pressure Sensor (MAP) provides manifold pressure information to the Engine Control Unit (ECU). The data is used to determine the air mass flow rate and required fuel for optimum combustion and ignition timing.
Barometric Pressure Sensors are designed to meet or exceed OE specifications in form, fit and function to ensure proper engine calibration at varying pressures

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$50.99

National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:

Low swell in hydrocarbon fluids
Design type: spring loaded; multi-lip
Provides good low temperature capability
Temperature range: -40°F to 225°F; -40°C to 107°C
Delivers quality and reliable performance for every type of repair

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$71.45

Crankshaft Seal

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$44.49

Recommended that the chain tensioner(s), sprocket(s), and guide(s) also be replaced when the chain is replaced, as these components play a vital role in system stability and accurate timing. Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance. Engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment. CAD designed and manufactured using premium materials. Refer to our online catalog for detailed application-specific information.

Product Features:

A timing chain synchronizes the rotation of the crankshaft and camshaft(s) ensuring proper timing and allows the engine’s valves to open and close during each cylinder’s firing. Available in kits or as a stand-alone product
Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
Engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment
CAD designed and manufactured using premium materials
Refer to our online catalog for detailed application-specific information
Pre-Stressed And Heat-Treated For Increased Durability. Precision Cut Plates And Rollers With Smooth Finish. Precision Pitch Control For Proper Chain To Sprocket Tooth Fit.

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$74.99

ACDelco GM Original Equipment Engine Timing Chains synchronize the rotation of the crankshaft and camshaft(s) in an internal combustion engine. They help ensure that the engine’s valves open and close at the proper time during each cylinder’s intake and exhaust strokes, and are GM-recommended replacements for your vehicle’s original components. These original equipment timing chains have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:

Synchronizes the rotation of the crankshaft and the camshaft(s) to help ensure that the engine’s valves open and close at the proper time during each cylinder’s intake and exhaust strokes
GM-recommended replacement part for your GM vehicle’s original factory component
Offering the quality, reliability, and durability of GM OE
Manufactured to GM OE specification for fit, form, and function

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$67.99

DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
SUPERIOR SEAL – Manufactured with rubber compounds to ensure a consistent and long-life seal across the entire oil pan
PREVENTS OVERTIGHTENING – Torque limiters help eliminate overtightening and gasket splitting and extruding (where applicable)
OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
ENGINEERING EXPERTISE – Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development

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$21.99

MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:

All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
Oil pan gasket set contains all gaskets required.
The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package

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$41.49

ACDelco GM Original Equipment Engine Crankshaft Position Sensors monitor the position and rotational speed of the crankshaft, and are GM-recommended replacements for your vehicle’s original components. The signal from the crankshaft position sensor is used by the engine control module to determine fuel injection and ignition timing. These original equipment engine crankshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:

This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
Helps keep engine timing and fuel injection running in sync
Helps provide proper alignment, positioning, and spacing for easy installation
Synchronizes engine valves and pistons for excellent engine performance
GM-recommended replacement part for your GM vehicle’s original factory component
Offering the quality, reliability, and durability of GM OE
Manufactured to GM OE specification for fit, form, and function

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$53.99

A leader in vehicle electronic solutions, each premium product meets or exceeds OE specifications in appearance, fit, and function, ensuring easy installation and excellent performance. The product has been tested under extreme environments.

Product Features:

Reliable circuit board and product structure design, 3D proofing, and field test verification to ensure correct signal output at all speeds.
Manufactured in an anti-static environment to ensure reliability and stability.
Extreme temperature and salt spray tests simulate real-world vehicle conditions to ensure durability and reliability.
Providing this premium product line, we meet the service professionals needs with the highest quality product every time the part comes out of the box.

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$15.49

GM Genuine Parts Engine Oil Pan Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:

Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
GM regularly updates production and service part designs to integrate new materials and technologies

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$5.99

Fuel Pump Mounting Gasket

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$14.99

GM Genuine Parts Engine Valve Lifter Guide are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:

Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
GM regularly updates production and service part designs to integrate new materials and technologies

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$51.99

Carquest Premium camshaft position sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium crankshaft and camshaft sensors are engineered with technology that provides increased output accuracy through a stronger, more consistent signal. Our sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium crankshaft and camshaft position sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:

Engineered with technology that provides increased accuracy with a stronger, more consistent signal
Sensors are based on proven hall effect and variable reluctance technology
Includes OE-style brackets, hold downs, hardware, or spacers as needed for each application.
O-rings and seals are included if required.
Weather-tight connectors prevent leaks and corrosion for better reliability.
Extensive design validation testing and 100% end-of-line tested.
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

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$45.99

Reliable circuit board and product structure design, 3D proofing, and field test verification to ensure correct signal output at all speeds.
Manufactured in an anti-static environment to ensure reliability and stability.
Extreme temperature and salt spray tests simulate real-world vehicle conditions to ensure durability and reliability.
Providing this premium product line, we meet the service professionals needs with the highest quality product every time the part comes out of the box.

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$38.99

This engine camshaft position sensor is designed to match the fit and function of an original sensor to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.

Product Features:

Direct replacement – this engine camshaft position sensor is designed to match the fit and function of an original sensor on specified vehicles
Ideal solution – engineered to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage
Durable construction – designed and manufactured to strict specifications for reliable performance
Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience

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$74.99

ACDelco GM Original Equipment Engine Camshaft Position Sensors monitor the rotational position of the camshaft(s), and are GM-recommended replacements for your vehicle’s original components. They provide a signal to the engine control module which compares the camshaft position with the crankshaft position to determine ignition and fuel injection timing. These original equipment engine camshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:

Helps keep engine timing and fuel injection running in sync
Helps provide proper alignment, positioning, and spacing for easy installation
Synchronizes engine valves and pistons for excellent engine performance
GM-recommended replacement part for your GM vehicle’s original factory component
Offering the quality, reliability, and durability of GM OE
Manufactured to GM OE specification for fit, form, and function

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$58.99

Direct replacement – this engine camshaft position sensor is designed to match the fit and function of an original sensor on specified vehicles
Ideal solution – engineered to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage
Durable construction – designed and manufactured to strict specifications for reliable performance
Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience

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$42.99

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered for the sealing repair environment
Validated for fit, form and function
Unsurpassed quality you can trust

FAQs for 2022 Chevrolet Express 4500 Engine Parts

Which Engine Parts are best-sellers for 2022 Chevrolet Express 4500s?

Out of 13 Engine Parts that fit 2022 Chevrolet Express 4500s, the following parts are the top sellers:

Gen III/IV Lifter Guide (11949076) – $14.99
Timing Chain (11680157) – $74.99
Engine Camshaft Position Sensor (12044983) – $29.99

What’s the price range for 2022 Chevrolet Express 4500 Engine Parts?

Engine Part prices for the 2022 Chevrolet Express 4500 start at $0.99 and go up to $113.99 for the most premium parts.

What’s the average price of a Engine Part for a 2022 Chevrolet Express 4500?

The average price for Engine Parts for the 2022 Chevrolet Express 4500 is $35.55. Keep in mind the variety of part types within our Engine Part category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Parts for other Chevrolet Express 4500 model years?

Yes, we currently carry Engine Parts for 15 model years of Chevrolet Express 4500s between 2009 and 2025. Engine Parts are bought most frequently for the following model years: 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Engine Parts for my 2022 Chevrolet Express 4500?

The cheapest 2022 Chevrolet Express 4500 Engine Parts we carry in stock are:

Engine Oil Dipstick Tube O-Ring (50251306) – $0.99
Fuel Pump Mounting Gasket (50251311) – $5.99
Oil Pan Gasket (12515458) – $6.29
Gen III/IV Lifter Guide (11949076) – $14.99
Oil Pan Seal (12518471) – $15.49

What types of Engine Parts do you sell for my 2022 Chevrolet Express 4500?

As of 11/2/25, these are some of the most in-demand types of Engine Parts for a 2022 Chevrolet Express 4500:

Can I get help with 2022 Chevrolet Express 4500 Engine Part orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Chevrolet Engine Parts and more.

What is your return policy for Chevrolet Express 4500 Engine Parts?

Advance Auto Parts keeps returns simple. For new Chevrolet Express 4500 Engine Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2022 Chevrolet Express 4500 Engine Parts

Felpro – VALVE COVER GASKET SET (Part No.VS 50821 R)

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50504 R)

Felpro – Engine Oil Dipstick Tube O-Ring (Part No.73889)

Melling – Stock Replacement Engine Assembly Lubricant, 4 oz. (Part No.M-10012)

Sealed Power – Engine Assembly Lubricant (Part No.55-400)

ACDelco – Air Pressure Sensor (Part No.12711681)

NTK – Manifold Absolute Pressure Sensor (Part No.MA0205)

National – Multi Purpose Seal (Part No.710601)

Mahle – Crankshaft Seal (Part No.A8060225317MAH)

Cloyes Gear – Engine Timing Chain (Part No.9-4205)

ACDelco – Timing Chain (Part No.12646386)

Felpro – Engine Oil Pan Gasket Set – PermaDry molded rubber (Part No.OS 30693 R)

MAHLE Original – Engine Oil Pan Gasket Set (Part No.OS32284)

GM Genuine Parts – Engine Crankshaft Position Sensor (Part No.12669636)

Carquest Premium – Crankshaft Sensor (Part No.CSC1065)

GM Genuine Parts – Oil Pan Seal (Part No.12621086)

Felpro – Fuel Pump Mounting Gasket (Part No.73158)

GM Genuine Parts – Gen III/IV Lifter Guide (Part No.12595365)

Carquest Premium – Engine Camshaft Position Sensor (Part No.CSA1465)

Carquest Premium – Camshaft Sensor (Part No.CSC1054)

Dorman – Camshaft Position Sensor (Part No.917-744)

GM Genuine Parts – Camshaft Position Sensor (Part No.213-3826)

Dorman – Camshaft Position Sensor (Part No.907-815)

Felpro – Engine Camshaft Thrust Plate (Part No.ES 73115)

GM Genuine Parts – Engine Camshaft Position Sensor (Part No.12623093)

Felpro – Engine Camshaft Thrust Plate (Part No.ES 73115)

ACDelco – Timing Chain (Part No.12646386)

GM Genuine Parts – Gen III/IV Lifter Guide (Part No.12595365)

GM Genuine Parts – Engine Crankshaft Position Sensor (Part No.12669636)

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50907 R)

GM Genuine Parts – Oil Pan Gasket (Part No.12666993)

Felpro – Fuel Pump Mounting Gasket (Part No.73158)