2021 Toyota Sequoia Cooling and Climate Controls

Below you will find various in-demand Toyota Cooling and Climate Controls, components and accessories for your 2021 Sequoia. Advance Auto Parts has popular Sequoia parts like Air Conditioning Parts, Blend Doors, Engine Cooling Parts and more. You’ll also find aftermarket and OEM Cooling and Climate Controls for other Sequoia model years including 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2022 and more. Select a category of 2021 Toyota Sequoia Cooling and Climate Controls below and start saving instantly.

Popular 2021 Toyota Sequoia Cooling and Climate Controls Categories

AC Compressor Without Clutch

Thermostats

Thermostat and Water Outlet Assemblies

Air Blend Door Actuators

Engine Cooling Fan Pulley Brackets

Coolant Reservoirs

Coolant Temperature Sensors

Heater Cores

Cabin Air Temperature Sensors

Water Outlets

Radiator Fan Control Relays

OE Cooling Fan Blades

Thermostat Seals

Accumulator and Receiver Driers

Thermostat and Water Outlet Gaskets

Water Pump Gaskets

AC High Pressure Side Switches

Engine Coolant Water Inlet Seals

Essential Cooling and Climate Controls for 2021 Toyota Sequoias

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$3.29

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

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$40.49

This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:

Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models.
Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking.
Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies

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$34.05

High quality OE replacement part with all components needed to complete the job

Product Features:

Contains gaskets, O-rings, or seals to properly replace the product
Brass construction for accurate temperature sensing
Color coded for easy identification
Zinc coated terminal to resist corrosion

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$99.99

Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications. Carquest Premium provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability. Carquest Premium offers certified heater cores that meet or exceed OE specifications and are all fitment checked in the actual vehicle’s HVAC heater module and are, thus, ready to be installed right out of the box for a “Drop-In Fit”. Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.

Product Features:

All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts

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$301.99

Product Features:

Designed, tested, and built by application
OE performance, fit, and appearance
Precision machined
Out of box installation

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$165.13

A/C Servo

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$157.61

The AISIN Water Pump contains no remanufactured parts and provides optimal cooling without creating excess load to the engine. The highest quality materials are used, creating stronger body design and resistance to corrosion.

Product Features:

OE-Equivalent and direct fit application.
100% new with no remanufactured parts.
Advanced technological design.
Carbon ceramic sealing.
Resistant to corrosion.
Optimum cooling performance and longevity.

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$17.79

Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

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$83.99

The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:

Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging

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$44.06

The Denso A/C Receiver Drier is manufactured to exact OEM specifications for quality fit and performance.

Product Features:

OE-Equivalent and Direct fit Application.
Meets or exceeds the vehicle manufacturer specifications.
Utilizes factory style fittings and connectors.
Includes the required o-rings and associated hardware

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$9.79

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

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$8.11

Water Pump Gasket

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$23.99

This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:

Heavy gauge stainless steel components offer increased reliability and long-lasting durability
Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
AccuSpring Design for stable temperature control and increased cabin comfort

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$3.29

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered and manufactured specifically for the repair environment
Unsurpassed quality you can trust
Validated for fit, form, and function

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$43.99

CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

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$386.99

As one of the world’s largest OE suppliers of A/C compressors, DENSO units are specified by most major vehicle manufacturers. DENSO First Time Fit A/C compressors are manufactured and tested to the strictest OE standards for unparalleled performance. At DENSO, we bring together everything we know as an air conditioning systems manufacturer to bring you the highest quality line of factory-new compressors available. When it comes to new compressors, you can’t do better than going with a unit manufactured by the OE supplier. At DENSO we know these units better than anyone because we originally designed them. Our compressors are built to meet DENSO’s unsurpassed reputation for technological superiority. You can relax knowing DENSO will give you the right part and the right fit the first time.

Product Features:

DENSO is the world’s largest OE supplier of A/C compressors
Each compressor is precision manufactured for exact replacement
Designed for high output and extended durability
Highest quality in the Aftermarket

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$14.99

Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:

Maintains proper cooling system pressure
Easy installation and removal
100% tested to ensure proper pressure and longevity
Meets all OEM specifications

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$10.36

The Sankei Switches radiator cap range has been developed to operate within original equipment manufacturer’s specifications. A faulty radiator cap can cause your car to boil-over at a lower temperature. Test or replace the coolant cap when servicing the cooling system.

Product Features:

Meets Original Equipment specifications.
Made from premium materials.
Designed to function on open cooling systems and overflow reservoir type systems.

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$166.57

Engineered to exacting OE specifications, AISIN fan blade makes cars lighter in weight and higher in performance through diversity of products for drive systems, engines, and vehicle bodies.

Product Features:

Light weight and high performance
Maintains optimal pressurization between fan and radiator
Decreases rotational mass for maximum air ventilation

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$114.99

Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:

Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade.
Quality construction – manufactured from premium materials for a long service life.
Excellent value – original equipment quality at a lower price
Quality tested – has undergone testing to ensure proper fit and performance

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$307.02

Cooling Fan Pulley B

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$148.99

This engine cooling fan pulley bracket is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this engine cooling fan pulley bracket matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this bracket is a reliable replacement for an original part that has failed due to fatigue.
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$134.99

This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part..

Product Features:

Direct replacement – this engine coolant reservoir matches the fit and function of the original part.
Ideal solution – engineered for a seamless installation
Durable construction – manufactured from quality materials to withstand underhood heat and vibration
Trustworthy design – backed by 100 years of automotive aftermarket experience

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$158.31

Dorman’s Engine Coolant Recovery Tank is designed for enduring use. It resists the expansion and cracking that extreme temperature fluctuations can cause. Plus, the durable plastic construction prevents coolant fluid loss.

Product Features:

Comes with reservoir cap
Level sensor included (where applicable)
Direct replacement for a proper fit every time
Quality tested to ensure trouble-free installation and performance

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$94.65

Four Seasons manufactures a high quality replacement Blower Motor that meets or exceeds OE design and performance.

Product Features:

OE-Equivalent.
Direct Fit Replacement.
Meet or exceed OE design and performance.
Magnet size and properties compare to or exceed OEM.
Manufacturing facility both QS9000 and ISO 9000 certified.
OE quality electrical components, brushes and bearings.
Balanced rotor assembly.

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$188.84

Blower Motor

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$45.99

We are proud to offer this CARQUEST product line: CARQUEST Water Outlets. Our products are engineered and tested to provide years of trouble free operation and designed to be hassle free OE replacement part that meets and/or exceeds OE standards. Backed by over 50 years of mobile temperature control experience, fix it once and fix it right with CARQUST Water Outlets and Thermostat Housings.

Product Features:

Meets and/or exceeds OEM standard
Includes quality gasket or O-ring to ensure proper seal (where applicable)
100% virgin resin material to insure durability
100% leak tested
Direct-fit replacement for ease of installation
Includes quality thermostat

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$40.99

Meets and/or exceeds OEM standard
Direct-fit replacement for ease of installation
100% leak tested

Upgrade your 2021 Toyota Sequoia with Top-Quality Cooling and Climate Controls

When it comes to maintaining or upgrading your 2021 Toyota Sequoia, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Toyota or enhancing its overall performance, Cooling and Climate Controls are key to keeping your Sequoia functioning at its best. At Advance Auto Parts, we offer a wide selection of 40 Cooling and Climate Controls for the 2021 Toyota Sequoia, designed to meet your needs without breaking the bank. From Air Conditioning Part replacements to Blend Doors upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2021 Toyota Sequoia at great prices. Our Cooling and Climate Controls inventory for this model ranges from just $2.33 to $591.99, with an average price of $107.46. Our 40 Cooling and Climate Controls in stock come from 16 trusted brands, so you’re sure to find the right part for your 2021 Toyota Sequoia without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2021 Toyota Sequoia, we stock popular OEM and aftermarket Cooling and Climate Controls from top names like Carquest Premium Motorad, and more. Carquest Premium Cooling and Climate Controls start at just $14.99 and boast an impressive 4 stars average rating from customers. With 444 customer reviews and counting, our 2021 Toyota Sequoia Cooling and Climate Controls have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 Toyota Sequoia is always ready to roll. We’re committed to providing you with everything you need to keep your Sequoia in top shape, all in one place. Start shopping confidently below for your 2021 Toyota Sequoia!

Best-Selling Air Conditioning Parts for 2021 Toyota Sequoias

Enhance the driving experience in your Toyota with 5 quality Air Conditioning Part components, starting at $19.99.

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$591.99

Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.

Product Features:

Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
All new compressors must pass a helium leak test and pump up function test prior to packaging.
O-Rings and gaskets necessary for installation are included.

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$83.99

Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging

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$300.25

A/C Compressor

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$44.70

A/C Pressure Switch

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$19.99

Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:

All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
All accumulators and receiver driers are helium leak tested prior to packaging.
O-Rings necessary for installation are included.

Most Popular 2021 Toyota Sequoia Blend Doors

Customize your Toyota with 2 Blend Doors products like Air Blend Door Actuators, all priced under $183.99.

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$183.99

This air door actuator directly replaces the original actuator on specific vehicle years, makes, models, configurations and positions to restore proper HVAC operation. Please note that many vehicles have several different air door actuators, which are designed for specific positions and functions in the vehicle. To ensure you have what you need, carefully review the application notes for this part to verify it matches the position and function of the actuator you need to replace. In some online ordering systems, you may need to enter your vehicle information first to see the application notes for your vehicle. If you don’t know which actuator position you need to replace, consult a qualified service technician.

Product Features:

Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations.
Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace.
Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience

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$165.13

A/C Servo

Top Picks for 2021 Toyota Sequoia Engine Cooling Parts

Upgrade Toyota Sequoias with top-quality Engine Cooling Parts parts, including 26 OEM and aftermarket selections for your 2021 model.

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$125.99

Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:

100% tested for reliable performance
Durable housing features precisely machined mounting surface for proper sealing and fitment
Equipped with weep chamber or similar feature to help prevent unnecessary replacement
Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
All gaskets or seals necessary for water pump are included
This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components

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$60.99

Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

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$45.99

Meets and/or exceeds OEM standard
Includes quality gasket or O-ring to ensure proper seal (where applicable)
100% virgin resin material to insure durability
100% leak tested
Direct-fit replacement for ease of installation
Includes quality thermostat

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$11.27

Meets Original Equipment specifications.
Made from premium materials.
Designed to function on open cooling systems and overflow reservoir type systems.

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$14.99

Maintains proper cooling system pressure
Easy installation and removal
100% tested to ensure proper pressure and longevity
Meets all OEM specifications

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$25.84

An electrical relay is sort of a magical device: it takes a small electrical signal and uses it to manage a much more powerful current, permitting electrical systems to be both lighter and more dependable at the same time. DENSO has supplied quality relays to the OE automotive world for over 60 years. The very same performance and dependability are available across the replacement aftermarket with DENSO First Time Fit® relays. Engineered to meet the most stringent automaker standards for shock resistance, arcing, and thermal protection, DENSO auto relays feature the lowest return rates in the industry; that equals value for car owners and repair facilities alike

Product Features:

Lead-free, solderless construction prevents heat shock and arcing
Controlled contact force, self-adjusting air gap increase longevity of the internal parts
Industry-standard packaging and footprint
Low heat generation
Reduced electrical loads
Built to last

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$301.99

Product Features:

Designed, tested, and built by application
OE performance, fit, and appearance
Precision machined
Out of box installation

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$24.49

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

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$190.84

OE-Equivalent and direct fit application.
100% new with no remanufactured parts.
Advanced technological design.
Carbon ceramic sealing.
Resistant to corrosion.
Optimum cooling performance and longevity.

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$70.35

NTC offers a full line of thermostats to replace your original equipment thermostat. This includes a wide variety of temperature ranges all designed to operate within OEM specifications.

Product Features:

Strict quality control, and functional testing
Self-cleaning and self-aligning thermostat valve
Original equipment design provides exact fit and performance
Precise sealing edges reduce leakage and premature cooling
Temperature sensitive heat motor provides consistent valve response for smooth performance and precise engine cooling
Stainless steel assembly and springs are engineered for long life

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$114.99

Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade.
Quality construction – manufactured from premium materials for a long service life.
Excellent value – original equipment quality at a lower price
Quality tested – has undergone testing to ensure proper fit and performance

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$33.13

The Sankei Switches Engine Coolant Temperature Sensor is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:

Premium Original Equipment replacement
Provides performance and dependability
Manufactured to meet OE specifications

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$3.29

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered and manufactured specifically for the repair environment
Unsurpassed quality you can trust
Validated for fit, form, and function

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$274.34

Water Pump Bracket

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$185.89

The NPW Engine Cooling Fan Clutch is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:

Premium aftermarket replacement
Provides performance and dependability
Manufactured to meet OE specifications

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$134.99

Direct replacement – this engine coolant reservoir matches the fit and function of the original part.
Ideal solution – engineered for a seamless installation
Durable construction – manufactured from quality materials to withstand underhood heat and vibration
Trustworthy design – backed by 100 years of automotive aftermarket experience

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$126.73

The GMB Water Pump contains no remanufactured components and is designed to combat engine overheating associated with higher RPM, performance and high load applications. All GMB Water Pumps feature a precision ground, heavy duty steel bearing that`s completely sealed and lubricated for life. A specially modified, high performance impeller eliminates cavitation at high RPM`s, maintaining maximum volumetric flow of coolant, thus reducing engine temperature and increasing horsepower.

Product Features:

OE-Equivalent and direct fit application.
100% new with no remanufactured parts.
High flow design
Factory lubricated bearing assembly
Precision ground shaft and hub
OE quality forged housing for maximum coolant flow
Precision built and balanced
Pressed on impeller for increased water flow
Unique no sealed required gasket
Unitized seal protects bearings and provides long life leak free performance.
Factory sealed precision ground one piece bearing assembly

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$82.99

DENSO’s engine coolant temperatures sensors are manufactured to the strictest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.

Product Features:

OE technology adapted for the aftermarket
Reduces emissions, increased performance
Delivers the highest reliability and detection accuracy

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$44.57

Thermostat Assembly

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$40.49

Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models.
Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking.
Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies

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$8.79

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered and manufactured specifically for the repair environment
Unsurpassed quality you can trust
Validated for fit, form, and function

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$7.98

Radiator Cap

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$5.62

Water Outlet Gasket

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$3.68

The Mahle Engine Coolant Thermostat Gasket is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:

Seals the thermostat housing and helps prevent coolant from leaking from the engine for proper engine temperature
Premium Original Equipment replacement
Provides performance and dependability
Manufactured to meet OE specifications

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$3.29

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

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$2.33

Water Pipe O-Ring

In-Demand Blower Motor and Related Products for 2021 Toyota Sequoias

Select from 4 premium Blower Motor and Related Products parts for your 2021 Toyota Sequoia, with prices ranging from $123.99 to $188.84.

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$188.84

Blower Motor

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$169.83

Blower Motor

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$152.99

Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Functionally Equivalent to OE Design
Each unit is 100% tested for functional performance and operational noise
Hermetically Sealed & Thermally Protected Electronics

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$123.99

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor

Most Sold 2021 Toyota Sequoia Heating Parts

Explore our best-selling Toyota parts for the 2021 Sequoia among 2 OEM and aftermarket options starting from $93.99.

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$199.99

All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts

from

$93.99

All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts

Top-Rated Cooling and Climate Controls Brands For Your 2021 Toyota Sequoia

Shop for the best-rated brands offering Cooling and Climate Controls and other products for your 2021 Toyota Sequoias. Below you’ll find some of our best rated Cooling and Climate Controls from Carquest Premium and Motorad, and more. Cooling and Climate Controls from these brands that fit a 2021 Sequoia start at just $14.99 and are rated as high as 4 stars. OEM and aftermarket Cooling and Climate Controls don’t get more top quality, durable, and affordable than from the brands below.

Popular Carquest Premium 2021 Toyota Sequoia Cooling and Climate Controls

When it comes to maintaining or upgrading your 2021 Toyota Sequoia, using quality Cooling and Climate Controls is essential to ensure durability and a perfect fit. Carquest Premium ticks all of those boxes. We offer a wide selection of Carquest Premium Cooling and Climate Controls, specifically designed for the 2021 Toyota Sequoia. With over 11 Carquest Premium brand Cooling and Climate Controls in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $14.99, with an average price of just $159.63. Plus, with over 144 customer reviews and an average rating of 4 stars, you can trust that our Carquest Premium Cooling and Climate Controls will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

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$591.99

This product is not rated

A/C New, with Clutch, with 10SR19C Compressor

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from
$301.99

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Severe Duty Fan Clutch – Thermal Reverse Rotation

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from
$199.99

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Heater Core

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Popular Motorad 2021 Toyota Sequoia Cooling and Climate Controls

Motorad auto parts is one of the highest quality Cooling and Climate Control brands in the market. Any 2021 Toyota Sequoia owner should feel confident when installing genuine Motorad parts in their vehicle. To ensure the best fit and performance for your 2021 Sequoia, Advance Auto Parts carries a full inventory of 1 Motorad Cooling and Climate Controls. Plus you will be keeping your Toyota in peak condition while saving money because prices on these Motorad Cooling and Climate Controls range up to $60.99, plus, with more than 3 customer reviews and an impressive 4 stars average rating, you can be confident the Fram Cooling and Climate Controls below will deliver on both quality and value.

from
$60.99

(3)

Integrated Thermostat Housing: With Seal, 180 Degrees

“Works and fit just fine.”

FAQs for 2021 Toyota Sequoia Cooling and Climate Controls

Which Cooling and Climate Controls are best-sellers for 2021 Toyota Sequoias?

Out of 40 Cooling and Climate Controls that fit 2021 Toyota Sequoias, the following parts are the top sellers:

First Time Fit Relay (11075985) – $25.84
Severe Duty Fan Clutch – Thermal Reverse Rotation (11822329) – $301.99
Engine Water Pump Gasket (99992773) – $24.49

What’s the price range for 2021 Toyota Sequoia Cooling and Climate Controls?

Cooling and Climate Control prices for the 2021 Toyota Sequoia start at $2.33 and go up to $591.99 for the most premium parts.

What’s the average price of a Cooling and Climate Control for a 2021 Toyota Sequoia?

The average price for Cooling and Climate Controls for the 2021 Toyota Sequoia is $107.46. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Cooling and Climate Controls for other Toyota Sequoia model years?

Yes, we currently carry Cooling and Climate Controls for 23 model years of Toyota Sequoias between 2001 and 2024. Cooling and Climate Controls are bought most frequently for the following model years: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Cooling and Climate Controls for my 2021 Toyota Sequoia?

The cheapest 2021 Toyota Sequoia Cooling and Climate Controls we carry in stock are:

Water Pipe O-Ring (12086677) – $2.33
Engine Coolant Thermostat Housing Gasket (99992774) – $3.29
Engine Coolant Outlet Gasket (99992776) – $3.29
Engine Coolant Thermostat Gasket (11648339) – $3.68
Water Outlet Gasket (12568647) – $5.62

What are the top-rated Cooling and Climate Controls that fit the 2021 Toyota Sequoia?

Out of 444 reviews by customers, our 2021 Toyota Sequoia Cooling and Climate Controls have an average customer rating of . These are some of the highest-rated Cooling and Climate Control types for the 2021 Toyota Sequoia and their top-rated products:

Engine Cooling Parts
- Integrated Thermostat Housing: With Seal, 180 Degrees (11357585) – $60.99
- Thermostat Housing: Gasket Included (11339419) – $45.99
- Engine Water Pump: New, Gasket/Seals Included (10244956) – $125.99

What types of Cooling and Climate Controls do you sell for my 2021 Toyota Sequoia?

As of 2/5/25, these are some of the most in-demand types of Cooling and Climate Controls for a 2021 Toyota Sequoia:

Can I get help with 2021 Toyota Sequoia Cooling and Climate Control orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Toyota Cooling and Climate Controls and more.

What is your return policy for Toyota Sequoia Cooling and Climate Controls?

Advance Auto Parts keeps returns simple. For new Toyota Sequoia Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2021 Toyota Sequoia Cooling and Climate Controls

Felpro – Engine Coolant Outlet Gasket (Part No.35893)

Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 180 Degrees (Part No.902-5136)

Factory Air – Coolant Temp Sensor Switch (Part No.36424)

Carquest Premium – Heater Core (Part No.399286)

Carquest Premium – Severe Duty Fan Clutch – Thermal Reverse Rotation (Part No.216073)

Santech – A/C Servo (Part No.R20401522466SII)

AISIN – OE Replacement Water Pump (Part No.G3000167168ASC)

Carquest Premium – Multi Purpose Relay (Part No.RAA2117)

Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA1745)

DENSO – A/C Receiver Drier (Part No.R10401319928ND)

Felpro – Engine Coolant Outlet Gasket (Part No.35941)

NPW – Water Pump Gasket (Part No.G3040165863NPW)

Motorad UltraStats – Thermostat: 170 Degrees (Part No.5302-170)

Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35891)

Carquest Premium – Ambient Air Temperature Sensor (Part No.WTA1121)

DENSO – New Compressor With Clutch (Part No.471-1411)

Carquest Premium – Radiator Cap: 13 PSI (Part No.10241)

Sankei Switches – Sankei Switches Radiator Cap (Part No.G1010281394SAK)

AISIN – Engine Cooling Fan Blade (Part No.G5050668663ASC)

Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.620-573)

Aisan – Cooling Fan Pulley B (Part No.G5055147590ASC)

Dorman – Engine Cooling Fan Pulley Bracket (Part No.300-820)

Dorman – Fan Shroud With Integrated Coolant Reservoir (Part No.603-049)

Dorman – Coolant Reservoir – Expansion Tank (Part No.G1030279200DOR)

Four Seasons – Blower Motor (Part No.R203166589AIR)

VDO – Blower Motor (Part No.R2031419797VDO)

Carquest Premium – Thermostat Housing: Gasket Included (Part No.85953)

Carquest Premium – Coolant Housing/Water Outlet (Part No.85059)

Carquest Premium – A/C New, with Clutch, with 10SR19C Compressor (Part No.T158327)

Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA1745)

Autopart International Inc – A/C Compressor (Part No.R10003199250API)

Santech – A/C Pressure Switch (Part No.R1054261110SII)

Carquest Premium – A/C Desiccant Bag Kit (Part No.T83233)

Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-962)

Santech – A/C Servo (Part No.R20401522466SII)

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T2300)

Motorad – Integrated Thermostat Housing: With Seal, 180 Degrees (Part No.637-180)

Carquest Premium – Thermostat Housing: Gasket Included (Part No.85953)

Sankei Switches – Sankei Switches Radiator Cap (Part No.G101045813SAK)

Carquest Premium – Radiator Cap: 16 PSI (Part No.10242)

DENSO – First Time Fit Relay (Part No.P2020194560ND)

Carquest Premium – Severe Duty Fan Clutch – Thermal Reverse Rotation (Part No.216073)

Felpro – Engine Water Pump Gasket (Part No.35889)

AISIN – OE Replacement Water Pump (Part No.G3000382056ASC)

NTC – NTC Thermostat Assembly (Part No.G4002413618NTC)

Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.620-573)

Sankei Switches – Engine Coolant Temperature Sensor (Part No.C6020243726SAK)

Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35891)

Aisan – Water Pump Bracket (Part No.G3012442124ASC)

NPW – Engine Cooling Fan Clutch (Part No.G5010661061NPW)

Dorman – Fan Shroud With Integrated Coolant Reservoir (Part No.603-049)

GMB – GMB Water Pump (Part No.G3000382056GMB)

DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)

Autopart International Inc – Thermostat Assembly (Part No.G40021943958API)

Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 180 Degrees (Part No.902-5136)

Felpro – Engine Coolant Outlet Gasket (Part No.35886)

Autopart International Inc – Radiator Cap (Part No.G10101936436API)

Mahle – Water Outlet Gasket (Part No.G3045477049MAH)

Mahle – Engine Coolant Thermostat Gasket (Part No.G4031308106MAH)

Felpro – Engine Coolant Outlet Gasket (Part No.35893)

Ishino Stone – Water Pipe O-Ring (Part No.G2026122112ISH)

VDO – Blower Motor (Part No.R2031419797VDO)

Autopart International Inc – Blower Motor (Part No.R20312022861API)

Carquest Premium – Blower Motor: With Wheel (Part No.76500)

Carquest Premium – Blower Motor: With Wheel (Part No.75076)

Carquest Premium – Heater Core (Part No.910540)

Carquest Premium – Heater Core (Part No.910538)