2021 Lexus RX350 Engine Parts

Essential Engine Parts for 2021 Lexus RX350s

Cloyes Gear – Engine Timing Chain (Part No.9-4215)

Engine Timing Chain

from

$122.99
A timing chain synchronizes the rotation of the crankshaft and camshaft(s) ensuring proper timing and allows the engine’s valves to open and close during each cylinder’s firing. Available in kits or as a stand-alone product, our chains are pre-stressed and heat-treated for increased durability. Our chains are engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment

Product Features:
  • Recommended that the chain tensioner(s), sprocket(s), and guide(s) also be replaced when the chain is replaced, as these components play a vital role in system stability and accurate timing
  • Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
  • Engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment
  • CAD designed and manufactured using premium materials
  • Refer to our online catalog for detailed application-specific information
  • Pre-Stressed And Heat-Treated For Increased Durability. Precision Cut Plates And Rollers With Smooth Finish. Precision Pitch Control For Proper Chain To Sprocket Tooth Fit.
See More

Original Equipment – Timing Chain (Part No.A5100278463OEA)

Timing Chain

from

$33.60
Timing Chain

Cloyes Gear – Engine Timing Chain (Part No.9-4216)

Engine Timing Chain

from

$36.99
A timing chain synchronizes the rotation of the crankshaft and camshaft(s) ensuring proper timing and allows the engine’s valves to open and close during each cylinder’s firing. Available in kits or as a stand-alone product, our chains are pre-stressed and heat-treated for increased durability. Our chains are engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment

Product Features:
  • Recommended that the chain tensioner(s), sprocket(s), and guide(s) also be replaced when the chain is replaced, as these components play a vital role in system stability and accurate timing
  • Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
  • Engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment
  • CAD designed and manufactured using premium materials
  • Refer to our online catalog for detailed application-specific information
  • Pre-Stressed And Heat-Treated For Increased Durability. Precision Cut Plates And Rollers With Smooth Finish. Precision Pitch Control For Proper Chain To Sprocket Tooth Fit.
See More

Dorman – Camshaft Position Sensor (Part No.907-856)

Camshaft Position Sensor

from

$141.99
This engine camshaft position sensor is designed to match the fit and function of an original sensor to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.

Product Features:
  • Direct replacement – this engine camshaft position sensor is designed to match the fit and function of an original sensor on specified vehicles.
  • Ideal solution – engineered to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

DENSO – Camshaft Position Sensor (Part No.196-1001)

Camshaft Position Sensor

from

$189.99
DENSO’s camshaft position sensors are manufactured to the strictest OE standards resulting in unsurpassed reliability durability and detection accuracy. DENSO’s camshaft position sensors offer leading edge sensing technology which helps control ignition timing more precisely.

Product Features:
  • OE technology adapted for the aftermarket
  • Reduces emissions, increased performance
  • Delivers the highest reliability and detection accuracy
See More

Carquest Premium – Engine Camshaft Position Sensor (Part No.CSA1992)

Engine Camshaft Position Sensor

from

$82.99
A leader in vehicle electronic solutions, each premium product meets or exceeds OE specifications in appearance, fit, and function, ensuring easy installation and excellent performance. The product has been tested under extreme environments, including thermal shock and vibration, with unparalleled reliability, durability, and accuracy.

Product Features:
  • Products are produced in ISO 14001 and IATF 16949 certified facilities to ensure the highest quality and consistency throughout the production process.
  • Reliable circuit board and product structure design, 3D proofing, and field test verification to ensure correct signal output at all speeds.
  • Manufactured in an anti-static environment to ensure reliability and stability.
  • Extreme temperature and salt spray tests simulate real-world vehicle conditions to ensure durability and reliability.
  • Providing this premium product line, we meet the service professionals needs with the highest quality product every time the part comes out of the box.
See More

Elring – AT Filter O-Ring (Part No.J5001461422ELR)

AT Filter O-Ring

from

$1.45
AT Filter O-Ring

Anchor – Engine Mount: Rear, 1 Piece (Part No.10108)

Engine Mount: Rear, 1 Piece

from

$120.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to Applicable to LEXUS 16-21;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2016-2021
  • Weight approx: 3 Lbs
See More

Anchor – Engine Mount: Front, 1 Piece (Part No.9993)

Engine Mount: Front, 1 Piece

from

$101.79
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to Applicable to LEXUS 13-15;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2013-2015
  • Weight approx: 6 Lbs
  • HYDRAULIC
  • WITH VACUUM
See More

Anchor – Engine Mount: Front, 1 Piece (Part No.10112)

Engine Mount: Front, 1 Piece

from

$113.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to Applicable to LEXUS 16-21;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2016-2021
  • Weight approx: 6 Lbs
  • HYDRAULIC
See More

Dorman – Engine Oil Pan: Direct Fit, Steel, Rear Sump (Part No.264-342)

Engine Oil Pan: Direct Fit, Steel, Rear Sump

from

$118.99
Oil pan leaking? This engine oil pan is precision-engineered to match the original equipment pan on specific vehicle years, makes and models for a reliable replacement.

Product Features:
  • Direct replacement – this engine oil pan is made to match the original pan on specific vehicles.
  • Complete assembly – includes replacement pan and drain plugs to match original components.
  • Durable design – high-strength coating prevents future corrosion
  • Trustworthy value – backed by team of engineers and quality control experts in the United States
See More

KAI – Engine Oil Pan (Part No.SPITOP33A)

Engine Oil Pan

from

$102.99
New Standard Replacement Oil Pan

Product Features:
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
See More

Dorman – Engine Oil Pan (Part No.266-003)

Engine Oil Pan

from

$173.99
Oil pan leaking? This engine oil pan is precision-engineered to match the original equipment pan on specific vehicle years, makes and models for a reliable replacement.

Product Features:
  • Direct replacement – this engine oil pan is made to match the original pan on specific vehicles
  • Complete assembly – includes replacement pan and drain plugs to match original components
  • Durable design – high-strength coating prevents future corrosion
  • Trustworthy value – backed by team of engineers and quality control experts in the United States
See More

FAG US – SHAFT SEAL (Part No.SS3385)

SHAFT SEAL

from

$47.99
SHAFT SEAL

NOK – Crankshaft Seal (Part No.A8060283132NOK)

Crankshaft Seal

from

$20.65
Crankshaft Seal

Koyo – Crankshaft Seal (Part No.A8060283132KOY)

Crankshaft Seal

from

$20.49
Crankshaft Seal

Mahle – Oil Drain Plug Gaske (Part No.A6120121244MAH)

Oil Drain Plug Gaske

from

$1.67
Oil Drain Plug Gaske

Ishino – Oil Filler Cap Gasket (Part No.A6150149731ISH)

Oil Filler Cap Gasket

from

$3.83
Oil Filler Cap Gasket

Felpro – VALVE STEM SEAL SET (Part No.SS 72878)

VALVE STEM SEAL SET

from

$51.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • RIGHT TYPE — Valve stem seals designs are application-specific for the repair occasion using either deflector (umbrella) seals, O-ring style or positive seals
  • QUALITY MATERIALS — Each valve stem seal features materials based on the specific application for your vehicle repair
  • ENGINEERING EXPERTISE — Parts are reviewed, validated and approved by Fel-Pro engineers through rigorous research, development and testing
  • INSTALLATION AID — Installation tool included to protect inner lip of seal from damage during seal installation
  • COVERAGE — Available for domestic and foreign nameplate vehicles
See More

Ishino – Valve Stem Seal (Part No.A8070180151ISH)

Valve Stem Seal

from

$4.36
Valve Stem Seal

Ishino – Valve Stem Seal (Part No.A8070180150ISH)

Valve Stem Seal

from

$5.67
Valve Stem Seal

Upgrade your 2021 Lexus RX350 with Top-Quality Engine Parts

When it comes to maintaining or upgrading your 2021 Lexus RX350, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Engine Parts are key to keeping your RX350 functioning at its best. At Advance Auto Parts, we offer a wide selection of 18 Engine Parts for the 2021 Lexus RX350, designed to meet your needs without breaking the bank. From Engine Internal replacements to Engine Timing Parts upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Engine Parts for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Engine Parts for your 2021 Lexus RX350 at great prices. Our Engine Parts inventory for this model ranges from just $1.45 to $189.99, with an average price of $71.17. Our 18 Engine Parts in stock come from 12 trusted brands, so you’re sure to find the right part for your 2021 Lexus RX350 without overspending.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Engine Part upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 Lexus RX350 is always ready to roll. We’re committed to providing you with everything you need to keep your RX350 in top shape, all in one place. Start shopping confidently below for your 2021 Lexus RX350!

Best-Selling Engine Internals for 2021 Lexus RX350s

Enhance the driving experience in your Lexus with 1 quality Engine Internal components, starting at $24.77.

NOK – Crankshaft Seal (Part No.A8060663374NOK)

Crankshaft Seal

from

$24.77
Crankshaft Seal

Most Popular 2021 Lexus RX350 Engine Timing Parts

Customize your Lexus with 3 Engine Timing Parts products like Timing Chains, all priced under $55.58.

Cloyes Gear – Engine Timing Chain (Part No.9-4216)

Engine Timing Chain

from

$36.99
A timing chain synchronizes the rotation of the crankshaft and camshaft(s) ensuring proper timing and allows the engine’s valves to open and close during each cylinder’s firing. Available in kits or as a stand-alone product, our chains are pre-stressed and heat-treated for increased durability. Our chains are engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment

Product Features:
  • Recommended that the chain tensioner(s), sprocket(s), and guide(s) also be replaced when the chain is replaced, as these components play a vital role in system stability and accurate timing
  • Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
  • Engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment
  • CAD designed and manufactured using premium materials
  • Refer to our online catalog for detailed application-specific information
  • Pre-Stressed And Heat-Treated For Increased Durability. Precision Cut Plates And Rollers With Smooth Finish. Precision Pitch Control For Proper Chain To Sprocket Tooth Fit.
See More

Iwis – Timing Chain (Part No.A5100278463IWI)

Timing Chain

from

$55.58
Timing Chain

Original Equipment – Timing Chain (Part No.A5100278463OEA)

Timing Chain

from

$33.60
Timing Chain

Top Picks for 2021 Lexus RX350 Camshafts

Upgrade Lexus RX350s with top-quality Camshafts parts, including 5 OEM and aftermarket selections for your 2021 model.

DENSO – Camshaft Position Sensor (Part No.196-1001)

Camshaft Position Sensor

from

$189.99
DENSO’s camshaft position sensors are manufactured to the strictest OE standards resulting in unsurpassed reliability durability and detection accuracy. DENSO’s camshaft position sensors offer leading edge sensing technology which helps control ignition timing more precisely.

Product Features:
  • OE technology adapted for the aftermarket
  • Reduces emissions, increased performance
  • Delivers the highest reliability and detection accuracy
See More

DENSO – Camshaft Position Se (Part No.A40152671677ND)

Camshaft Position Se

from

$149.51
Camshaft Position Se

Dorman – Camshaft Position Sensor (Part No.907-856)

Camshaft Position Sensor

from

$141.99
This engine camshaft position sensor is designed to match the fit and function of an original sensor to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.

Product Features:
  • Direct replacement – this engine camshaft position sensor is designed to match the fit and function of an original sensor on specified vehicles.
  • Ideal solution – engineered to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

Autopart International Inc – Camshaft Position Se (Part No.A40152003736API)

Camshaft Position Se

from

$71.01
Camshaft Position Se

WSO – Camshaft Position Se (Part No.A4015421340WSO)

Camshaft Position Se

from

$66.60
Camshaft Position Se

In-Demand Engine Mounts for 2021 Lexus RX350s

Select from 3 premium Engine Mounts parts for your 2021 Lexus RX350, with prices ranging from $84.99 to $120.99.

Anchor – Engine Mount: Rear, 1 Piece (Part No.10108)

Engine Mount: Rear, 1 Piece

from

$120.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to Applicable to LEXUS 16-21;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2016-2021
  • Weight approx: 3 Lbs
See More

Anchor – Engine Mount: Front, 1 Piece (Part No.10112)

Engine Mount: Front, 1 Piece

from

$113.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to Applicable to LEXUS 16-21;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2016-2021
  • Weight approx: 6 Lbs
  • HYDRAULIC
See More

Anchor – Engine Mount: Right, 1 Piece (Part No.10102)

Engine Mount: Right, 1 Piece

from

$84.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to Applicable to LEXUS 16-21;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2016-2021
  • Weight approx: 7 Lbs
  • HYDRAULIC
See More

Most Sold 2021 Lexus RX350 Engine Gaskets and Seals

Explore our best-selling Lexus parts for the 2021 RX350 among 5 OEM and aftermarket options starting from $1.45.

Mahle – Oil Drain Plug Gaske (Part No.A6120121244MAH)

Oil Drain Plug Gaske

from

$1.67
Oil Drain Plug Gaske

Ishino – Valve Stem Seal (Part No.A8070180150ISH)

Valve Stem Seal

from

$5.67
Valve Stem Seal

Ishino – Valve Stem Seal (Part No.A8070180151ISH)

Valve Stem Seal

from

$4.36
Valve Stem Seal

Ishino – Oil Filler Cap Gasket (Part No.A6150149731ISH)

Oil Filler Cap Gasket

from

$3.83
Oil Filler Cap Gasket

Elring – AT Filter O-Ring (Part No.J5001461422ELR)

AT Filter O-Ring

from

$1.45
AT Filter O-Ring

FAQs for 2021 Lexus RX350 Engine Parts

Which Engine Parts are best-sellers for 2021 Lexus RX350s?

Out of 18 Engine Parts that fit 2021 Lexus RX350s, the following parts are the top sellers:

What’s the price range for 2021 Lexus RX350 Engine Parts?

Engine Part prices for the 2021 Lexus RX350 start at $1.45 and go up to $189.99 for the most premium parts.

What’s the average price of a Engine Part for a 2021 Lexus RX350?

The average price for Engine Parts for the 2021 Lexus RX350 is $71.17. Keep in mind the variety of part types within our Engine Part category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Parts for other Lexus RX350 model years?

Yes, we currently carry Engine Parts for 17 model years of Lexus RX350s between 2007 and 2024. Engine Parts are bought most frequently for the following model years: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Engine Parts for my 2021 Lexus RX350?

The cheapest 2021 Lexus RX350 Engine Parts we carry in stock are:

What types of Engine Parts do you sell for my 2021 Lexus RX350?

As of 2/5/25, these are some of the most in-demand types of Engine Parts for a 2021 Lexus RX350:

Can I get help with 2021 Lexus RX350 Engine Part orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Engine Parts and more.

What is your return policy for Lexus RX350 Engine Parts?

Advance Auto Parts keeps returns simple. For new Lexus RX350 Engine Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.