2021 GMC Sierra 2500 HD Drivetrains

Essential 2021 GMC Sierra 2500 HD Drivetrains

Felpro – Drive Axle Shaft Flange Gasket (Part No.55350)

Drive Axle Shaft Flange Gasket

from

$4.79
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Unsurpassed quality you can trust
  • Validated for fit, form and function
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

Dorman – Axle Flange Gasket Kit (Part No.926-573)

Axle Flange Gasket Kit

from

$17.49
Ensure a leak-free repair when servicing axle bearings or parking brake shoes. This axle shaft flange seal is a direct replacement for the original gasket and should be replaced every time work is performed at the axle flange.

Product Features:
  • Ideal replacement – this axle shaft flange seal directly replaces the original gasket without having to visit the dealer
  • Required for routine service – this gasket should be replaced every time work is performed at the axle flange
  • Durable construction – this axle shaft flange gasket is made of tough, durable materials for leak-free performance
  • Quality tested – this flange gasket has been designed and tested for a guaranteed fit
See More

GM Genuine Parts – Rear Axle Shaft Seal (Part No.291-336)

Rear Axle Shaft Seal

from

$59.99
GM Genuine Parts Axle Shaft Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help keep dirt and water out of your axle shaft assembly and seal in lubricant. They conform to the rotating surface to help provide leak-free operation. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps keep dirt and water out of your axle shaft assembly
  • Conforms to the rotating surface to help provide leak-free operation
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

National – Axle Shaft Seal (Part No.710926)

Axle Shaft Seal

from

$89.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Axle Shaft Seal (Part No.S-710497)

Axle Shaft Seal

from

$19.79
Product Features:
  • Brand may vary by location
See More

SKF – Axle Seal (Part No.K4021403278SKF)

Axle Seal

from

$25.21
Axle Seal

ACDelco – Axle Seal (Part No.K4021429877ACD)

Axle Seal

from

$18.41
Axle Seal

Yukon Gear – Full-Floating Axle Seal For GM 14T (Part No.30018)

Full-Floating Axle Seal For GM 14T

from

$13.99
Full-floating axle seal for GM 14T.Yukon Mighty seal.

Product Features:
  • Rear axle seal
  • Fits GM 10.5″ 14 bolt truck
See More

National – Multi Purpose Seal (Part No.710497)

Multi Purpose Seal

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Yukon Gear – Inner Stub Axle Side Seal For GM 9.25" IFS (Part No.30146)

Inner Stub Axle Side Seal For GM 9.25" IFS

from

$17.99
Inner stub axle side seal for GM 9.25″ IFS.Yukon Mighty seal.

Product Features:
  • Inner stub axle seal
  • Fits GM 9.25″ IFS
See More

Yukon Gear – Redline Synthetic "Shock Proof" Oil With Positraction Additive – 4 Quarts (Part No.15005)

Redline Synthetic "Shock Proof" Oil With Positraction Additive - 4 Quarts

from

$148.99
Redline Synthetic “Shock Proof” Oil with positraction Additive. 4 Quarts.

Product Features:
  • Includes four quarts of Redline Shockproof oil and one 4oz bottle of Yukon positraction additive
See More

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$12.79
Product Features:
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks
  • Long-life friction modifiers and premium base oils help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • Enhanced cleaning additives help reduce varnish formation and keep the transmission running properly longer
  • Engineered with a unique blend of viscosity modifiers and base oils to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Yukon Gear – 3 Qt – Penzoil 80W90 Conventional Gear Oil (Part No.15002)

3 Qt - Penzoil 80W90 Conventional Gear Oil

from

$44.99
3 Qt. Penzoil 80W90 conventional gear Oil.

Product Features:
  • Includes three quarts of conventional oil
See More

Valvoline – ULV Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.888460)

ULV Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$18.29
Valvoline ULV is a full synthetic, ultra low viscosity transmission fluid specifically engineered for high speed automatic transmissions. Formulated to meet the performance requirements of the latest 9 & 10 speed transmission designs, including the Ford/GM 10R80 found in select Ford F-150 and Raptor trucks.

Product Features:
  • Formulated with premium synthetic base oils to achieve low viscosity and minimize deposits
  • Provides excellent thermal and oxidation performance
  • Durable friction modifiers help prevent shudder
  • Advanced anti-wear technology to better prevent gear wear
See More

Yukon Gear – Redline Synthetic "Shock Proof" Oil – 3 Quarts (Part No.15000)

Redline Synthetic "Shock Proof" Oil - 3 Quarts

from

$99.99
Redline Synthetic “Shock Proof” Oil. 3 Quarts.

Product Features:
  • Includes three quarts of Redline Shockproof oil
See More

Yukon Gear – Redline Synthetic "Shock Proof" Oil – 4 Quarts (Part No.15004)

Redline Synthetic "Shock Proof" Oil - 4 Quarts

from

$137.99
Redline Synthetic “Shock Proof” Oil. 4 Quarts.

Product Features:
  • Includes four quarts of Redline Shockproof oil
See More

Driveworks – Universal Joint (Part No.DW-355)

Universal Joint

from

$15.99
DRIVEWORKS Universal Joints are designed to meet or exceed OE fit, form, and function. These universal joints are set to provide superior quality and easy installation. DRIVEWORKS Universal Joints are constructed from quality materials for extended durability. DRIVEWORKS Universal Joints are pre-lubricated with premium grease to provide a longer service life. The grease fittings are pre-installed to allow for easy maintenance (where applicable).

Product Features:
  • The cross is hot forged for the higher torque and horsepower
  • The bearing cups are made by cold forging, having higher strength and better rigidity
  • Bearig cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
  • Lubrication grooves designed to ensure grease penetration to entire journal and needle bearings
  • Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
  • Snap rings are held to strict tolerances to ensure proper cup position and retention
  • Nitrile rubber seals to optimize grease retention and reduce contamination
See More

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.351A)

Greaseable Premium Universal Joint

from

$54.99
Backed by superior materials and rigorous testing, MOOG Heavy Duty universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:
  • BUILT TO LAST — Rugged design specifically engineered for fleets, off-highway and commercial vehicles
  • STRONG AND DURABLE — Bearing cups are cold-formed, case-hardened and precision ground for strength and durability
  • KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
  • GREASEABLE DESIGN — Drilled and tapped grease fitting holes for easy servicing and cross trunnions with large grease reservoirs with radial grease channels for grease distribution
  • INHIBITS PREMATURE WEAR — Cross trunnions ground to a 15-25 RMS finish for a smooth surface free of microscopic grooves that can cause premature wear
  • RELIABLE PERFORMANCE — Internal anti-drainback valve integrated into thrust washer controls lubrication flow and prevents dry startup
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
See More

MOOG Driveline Products – Non-Greaseable Super Strength Universal Joint (Part No.234)

Non-Greaseable Super Strength Universal Joint

from

$32.99
Backed by superior materials and rigorous testing, MOOG Super Strength universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:
  • BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
  • COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates
  • CORROSION PROTECTION — Exclusive MICRO SHIELDΓ┐ó coating protects against rust and corrosion
  • KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
  • STRONG AND DURABLE — Bearing cups are cold-forged, case-hardened and precision ground while steel cross is forged and carburized heat treated for strength and durability
See More

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.358)

Greaseable Premium Universal Joint

from

$52.99
Backed by superior materials and rigorous testing, MOOG Heavy Duty universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:
  • BUILT TO LAST — Rugged design specifically engineered for fleets, off-highway and commercial vehicles
  • STRONG AND DURABLE — Bearing cups are cold-formed, case-hardened and precision ground for strength and durability
  • KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
  • GREASEABLE DESIGN — Drilled and tapped grease fitting holes for easy servicing and cross trunnions with large grease reservoirs with radial grease channels for grease distribution
  • INHIBITS PREMATURE WEAR — Cross trunnions ground to a 15-25 RMS finish for a smooth surface free of microscopic grooves that can cause premature wear
  • RELIABLE PERFORMANCE — Internal anti-drainback valve integrated into thrust washer controls lubrication flow and prevents dry startup
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
See More

MOOG Driveline Products – Non-Greaseable Super Strength Universal Joint (Part No.296A)

Non-Greaseable Super Strength Universal Joint

from

$32.99
Backed by superior materials and rigorous testing, MOOG Super Strength® universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:
  • BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
  • CORROSION PROTECTION — Exclusive MICRO SHIELD coating protects against rust and corrosion
  • STRONG AND DURABLE — Cold-forged, case-hardened and precision-ground alloy steel crosses for durability
  • KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
  • COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates
See More

Yukon Gear – 1350 To 1410 Conversion U/Joint (Part No.42006)

1350 To 1410 Conversion U/Joint

from

$78.99
Yukon 1350 to 1410 conversion u/joint.
See More

MOOG Driveline Products – Non-Greaseable Super Strength Universal Joint (Part No.296)

Non-Greaseable Super Strength Universal Joint

from

$32.99
Backed by superior materials and rigorous testing, MOOG Super Strength® universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:
  • BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
  • CORROSION PROTECTION — Exclusive MICRO SHIELD coating protects against rust and corrosion
  • STRONG AND DURABLE — Cold-forged, case-hardened and precision-ground alloy steel crosses for durability
  • KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
  • COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates
See More

Yukon Gear – 1410 Lifetime Series U/Joint (Part No.42022)

1410 Lifetime Series U/Joint

from

$84.99
Yukon 1410 Lifetime Series U/Joint. 4.188″ span ring span. 1.188″ cap diameter. Outside snap ring.
See More

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.351C)

Greaseable Premium Universal Joint

from

$53.99
Backed by superior materials and rigorous testing, MOOG Anti-Galvanic universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installations.

Product Features:
  • INHIBITS GALVANIC REACTION — Designed specifically for aluminum yokes to avoid a galvanic reaction that leads to corrosion
  • STRONG AND DURABLE — Bearing cups are cold-forged, case-hardened and precision ground while steel cross is forged and carburized heat treated for strength and durability
  • CORROSION PROTECTION — Bearing cups and snap rings are chemically-coated to protect aluminum yokes
  • KEEPS DIRT OUT — Nitrile rubber grease seals with double lip design protects components from wear-causing contaminants
  • GREASABLE DESIGN — Radial design of bearing cups allows 360 Degrees lubricant distribution to all bearing surfaces to flush out contaminants and moisture to reduce corrosion and wear
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
See More

Driveworks – Universal Joint (Part No.DW-330)

Universal Joint

from

$15.99
DRIVEWORKS Universal Joints are designed to meet or exceed OE fit, form, and function. These universal joints are set to provide superior quality and easy installation. DRIVEWORKS Universal Joints are constructed from quality materials for extended durability. DRIVEWORKS Universal Joints are pre-lubricated with premium grease to provide a longer service life. The grease fittings are pre-installed to allow for easy maintenance (where applicable).

Product Features:
  • The cross is hot forged for the higher torque and horsepower
  • The bearing cups are made by cold forging, having higher strength and better rigidity
  • Bearig cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
  • Lubrication grooves designed to ensure grease penetration to entire journal and needle bearings
  • Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
  • Snap rings are held to strict tolerances to ensure proper cup position and retention
  • Nitrile rubber seals to optimize grease retention and reduce contamination
See More

Driveworks – Universal Joint (Part No.DW-354)

Universal Joint

from

$15.99
DRIVEWORKS Universal Joints are designed to meet or exceed OE fit, form, and function. These universal joints are set to provide superior quality and easy installation. DRIVEWORKS Universal Joints are constructed from quality materials for extended durability. DRIVEWORKS Universal Joints are pre-lubricated with premium grease to provide a longer service life. The grease fittings are pre-installed to allow for easy maintenance (where applicable).

Product Features:
  • The cross is hot forged for the higher torque and horsepower
  • The bearing cups are made by cold forging, having higher strength and better rigidity
  • Bearig cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
  • Lubrication grooves designed to ensure grease penetration to entire journal and needle bearings
  • Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
  • Snap rings are held to strict tolerances to ensure proper cup position and retention
  • Nitrile rubber seals to optimize grease retention and reduce contamination
See More

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.330C)

Greaseable Premium Universal Joint

from

$42.99
Backed by superior materials and rigorous testing, MOOG Anti-Galvanic universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installations.

Product Features:
  • INHIBITS GALVANIC REACTION — Designed specifically for aluminum yokes to avoid a galvanic reaction that leads to corrosion
  • STRONG AND DURABLE — Bearing cups are cold-forged, case-hardened and precision ground while steel cross is forged and carburized heat treated for strength and durability
  • CORROSION PROTECTION — Bearing cups and snap rings are chemically-coated to protect aluminum yokes
  • KEEPS DIRT OUT — Nitrile rubber grease seals with double lip design protects components from wear-causing contaminants
  • GREASABLE DESIGN — Radial design of bearing cups allows 360 Degrees lubricant distribution to all bearing surfaces to flush out contaminants and moisture to reduce corrosion and wear
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
See More

2021 GMC Sierra 2500 HD Drivetrains

You count on your 2021 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Drivetrains. With 9 Drivetrains ranging in price from $12.79 to $59.99, you’re sure to find everything you need for your 2021 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Drivetrains brand, we stock 5 different brands like Valvoline, Moog, and GM Genuine. 2021 GMC Sierra 2500 HD Drivetrains start as low as $12.79!

One of the best ways to find top quality OEM or aftermarket Drivetrains is by asking professionals. Short of that, you can shop with confidence thanks to our 4,014 extensive product reviews on 2021 GMC Sierra 2500 HD Drivetrains.

Did we mention you can order your Drivetrains from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Drivetrains inventory for your 2021 GMC Sierra 2500 HD below to get started!

Top-Rated Drivetrains Brands For Your 2021 GMC Sierra 2500 HD

Trusted Drivetrains OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2021 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like Valvoline, Moog, GM Genuine, and even more.

Popular Valvoline Drivetrains

You’ll find popular Valvoline brand products across Differentials. All are waiting to get your 2021 GMC Sierra 2500 HD back on the road. Some of the top-rated Valvoline products in these categories are:

FAQs for 2021 GMC Sierra 2500 HD Drivetrains

What are the most purchased Drivetrains for the 2021 GMC Sierra 2500 HD?

Out of 9 Drivetrains for the 2021 GMC Sierra 2500 HD, the most popular in our inventory are:
Greaseable Premium Universal Joint
from $54.99
This product is not rated
Greaseable Premium Universal Joint
U-Joints
Rear Axle Shaft Seal
from $59.99
This product is not rated
Rear Axle Shaft Seal
Axle Shaft Seals
Axle Flange Gasket Kit
from $17.49
This product is not rated
Axle Flange Gasket Kit
Axle Flange Gaskets