2021 GMC Sierra 2500 HD Ignition and Tune-Up Products

Essential Ignition and Tune-Up Products for 2021 GMC Sierra 2500 HDs

Carquest Premium – Ignition Switch (Part No.CSA1116)

Ignition Switch

from

$42.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Carquest – Ignition Switch (Part No.CS1107)

Ignition Switch

from

$42.99
High-quality products that meet OE appearance and performance to provide professional technicians and DIYers with a cost-effective solution.

Product Features:
  • Designed to OE standards for ease of installation
  • Copper alloy conductors ensure superior electrical conductivity with low resistive losses
  • Our parts are 100% tested to verify both mechanical and electrical switching performance
  • Robust design and high grade materials meet the stringent demands of today’s service professional
  • BWD is a global manufacturer of original equipment ignition products, complete quality control is maintained through the manufacturing process from componentry to finished product
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GM Genuine Parts – Ignition Switch (Part No.D1485F)

Ignition Switch

from

$51.99
GM Genuine Parts Ignition Starter are designed, engineered, and tested to rigorous standards, and are backed by General Motors. It is a multi-position switch that activates the ignition, accessory, and cranking circuits in your vehicle. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Work with vehicle electronics to help optimize vehicle capabilities
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – Ignition Switch (Part No.CSC5038)

Ignition Switch

from

$36.99
Ignition Switch

ACDelco – GM Original Equipment Ignition Knock (Detonation) Sensor (Part No.F6020352539ACD)

GM Original Equipment Ignition Knock (Detonation) Sensor

from

$130.00
An ACDelco GM Original Equipment Ignition Knock (Detonation) Sensor monitors the engine for pinging or spark knock, and is a GM-recommended replacement for your vehicle’s original component. The sensor creates a voltage signal based on the vibrations caused by erratic air/fuel mixture combustion; the engine control module uses this signal to adjust the ignition timing and air/fuel mixture. This original equipment ignition knock sensor has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Undergo the same stringent testing process as the original part
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Delphi – Knock Sensor (Part No.AS10017)

Knock Sensor

from

$71.99
Manufactured to meet or exceed OE requirements; Delphi Knock Sensors help maximize engine performance with all fuels; Delphi Knock Sensors prevent against engine damage from pre-ignition knocking.

Product Features:
  • Delphi knock sensors help maximize engine performance with all fuels
  • Delphi knock sensors prevent against engine damage from pre-ignition knocking
  • Calibrated for a wide variety of frequencies to detect shifts, and adjust to provide accurate signals to help maximize engine performance
  • Flat frequency response allows the same sensor to be used on different engines and the sensor responds to knock frequencies higher than the primary frequency
  • Ground-isolated design with two-wire shielded harness helps protect the sensor signal from electro-magnetic interference (EMI)
  • Self-generating piezoelectric design requires no power to the sensor
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Delphi – Flat Response Knock Sensor (Part No.F6020352539DEL)

Flat Response Knock Sensor

from

$93.40
As a global leader in engine and powertrain management systems technology, Delphi manufactures a Flat Response Engine Knock Sensor that is 100 percent OE, providing an exact fit and superior quality. The Delphi Flat Response Knock Sensor has a flat frequency response over a range of from 1 to 18 kHz, thus the same sensor can be used on different engines by simply adjusting the filter frequency of the signal processing electronics to match the knock frequency of the engine. In addition, the sensor responds to knock frequencies higher than the primary knock frequency. This allows the higher knock frequencies to be used by a control system, either individually or combined with the primary knock frequency

Product Features:
  • Self-generating piezoelectric design requires no power to the sensor
  • Flat frequency response allows the same senor to be used on different engines and the sensor responds to knock frequencies higher than the primary frequency
  • Ground-isolated design with two-wire shielded harness helps protect the sensor signal from electro-magnetic interference (EMI)
  • Large mounting hole accommodates mounting bolts up to 10mm in diameter
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Delphi – Knock Sensor (Part No.AS10261)

Knock Sensor

from

$21.99
Manufactured to meet or exceed OE requirements; Delphi Knock Sensors help maximize engine performance with all fuels; Delphi Knock Sensors prevent against engine damage from pre-ignition knocking.

Product Features:
  • Flat frequency response allows the same sensor to be used on different engines and the sensor responds to knock frequencies higher than the primary frequency
  • Delphi knock sensors prevent against engine damage from pre-ignition knocking
  • Calibrated for a wide variety of frequencies to detect shifts, and adjust to provide accurate signals to help maximize engine performance
  • Flat frequency response allows the same sensor to be used on different engines and the sensor responds to knock frequencies higher than the primary frequency
  • Ground-isolated design with 2-wire shielded harness helps protect the sensor signal from electro-magnetic interference (EMI)
  • Self-generating piezoelectric design requires no power to the sensor
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MSD Ignition – Wire Set; Street Fire; GM Truck; 4.8L; 5.3L; 6.0L; 98-05 (Part No.5574)

Wire Set; Street Fire; GM Truck; 4.8L; 5.3L; 6.0L; 98-05

from

$60.29
The street fire spark plug wires feature a low resistance conductor that’s wrapped in a sleek and durable black sleeve. The terminals are covered in black boots that protect the conductor from engine heat to ensure spark delivery.

Product Features:
  • Helically Wound Conductor
  • Suppresses Electro And Radio Noise
  • Great Strength And Durability
  • Heavy Duty Terminals For Secure Connection
  • 8mm Silicone/Synthetic Jacket Resists Heat
  • Improved Spark Delivery And Power
  • Silicone Boots Protect Against High Exhaust Temps
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ACDelco – GM Original Equipment Ignition Wire Set (Part No.F1020340076ACD)

GM Original Equipment Ignition Wire Set

from

$271.27
Built to match the original equipment in length and fit, ACDelco OES Ignition Wire Sets also offer a performance advantage over many aftermarket products.

Product Features:
  • ACDelco OES wire sets are designed to be like Original in critical areas such as cable length and diameter, terminal design and insulator position
  • Have broad coverage available for most vehicles on the road today from 1980 to present
  • Provide a high degree of Radio Frequency Interference (RFI) suppression
  • Are designed to offer fit, form and function for optimum performance
  • Kevlar reinforced fiberglass core in select sets for increased strength
  • Core sheathed in radio-static absorbent material for increased RFI suppression
  • Wire-wound, stainless steel alloy conductor for maximum spark delivery and RFI suppression on most applications
  • A layer of conductive heat-resistant latex for added durability
  • Insulating rubber-based compound inner jacket helps minimize voltage drop and enhance durability
  • Thick silicone outer jacket for excellent heat resistance
  • Limited lifetime warranty*
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Carquest Premium – Spark Plug Wire Set: 8 Wires, Increased performance, Designed for direct fit (Part No.35-8157)

Spark Plug Wire Set: 8 Wires, Increased performance, Designed for direct fit

from

$80.99
Product Features:
  • SAEJ2031 Class E cable resist heat (428 Deg. F), cold (-104 Deg. F), electrical interference, abrasion and oil.
  • Stainless steel magnetic winding delivers maximum voltage to the spark plug for more powerful, and longer spark resulting in optimum engine performance while reducing the chance for misfire, and eliminating radio static.
  • 100% Pure silicone external insulation resists oil penetration, for lifetime protection against wire set failure.
  • EPDM inner insulation stops power-robbing voltage leaks.
  • With Magnetic-impregnated Kevlar internal conductors – durable and break resistant
  • Engineered to meet OEM tolerances using variable pitch wire winding, creating better resistance to electric magnetic interference (E.M.I resistance).
  • Excellent interference suppression and consistent performance
  • Easy lock terminals for more convenient installation.
  • Thick silicon outer jacket for excellent heat resistance. Insulating EPDM based compound inner jacket helps minimize voltage drop and enhance durability.
  • Broad coverage available for most vehicles on the road today
  • Include grease pack to ensure easy installation and removal
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ACDelco – Professional Ignition Wire Set (Part No.F1020575903ACD)

Professional Ignition Wire Set

from

$115.93
Built to match the Original Equipment in length and fit, ACDelco Professional Ignition Wire Sets also offer a performance advantage over many aftermarket products.

Product Features:
  • Designed to match Original Equipment wire sets in critical areas such as cable length and diameter, terminal design and insulator position.
  • Have broad coverage available for most vehicles on the road today from 1980 to present.
  • Provide a high degree of Radio Frequency Interference (RFI) suppression.
  • Are designed to offer fit, form and function for optimum performance.
  • Kevlar®-reinforced fiberglass core in select sets for increased strength.
  • Core sheathed in radio-static-absorbent material for increased RFI suppression.
  • Wire-wound, stainless-steel alloy conductor for maximum spark delivery and RFI suppression on most applications.
  • A layer of conductive heat-resistant latex for added durability.
  • Insulating rubber-based compound inner jacket helps minimize voltage drop and enhance durability.
  • Thick silicone outer jacket for excellent heat resistance.
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DENSO – Original Equipment Quality Direct Ignition Coil (Part No.673-7105)

Original Equipment Quality Direct Ignition Coil

from

$59.99
As the innovator and leader in stick coil technology, DENSO has conducted superior testing and inspection processes to insure the highest quality ignition coil. Don’t be fooled by imitations – look for the DENSO name to be sure you’re getting the best.

Product Features:
  • First Time Fit
  • Built to DENSO Original Equipment Standards
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DENSO – Original Equipment Quality Direct Ignition Coil (Part No.673-7108)

Original Equipment Quality Direct Ignition Coil

from

$69.99
As the innovator and leader in stick coil technology, DENSO has conducted superior testing and inspection processes to insure the highest quality ignition coil. Don’t be fooled by imitations – look for the DENSO name to be sure you’re getting the best.
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NGK – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.48658)

Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece

from

$63.99
NGK ignition coils are manufactured to meet or exceed OE standards for the highest durability and operational performance, so they can be installed with confidence. NGK and their family of automotive products have over 80 year’s experience and are driven by extreme dedication to innovation, performance and quality. Developed and rigorously tested in our ISO 17025 accredited test lab under the most extreme conditions, NGK’s coil designs will outperform all others – far beyond operational environments a vehicle would actually experience

Product Features:
  • OE QUALITY: Vacuum-sealed premium epoxy resin and thermoplastic coil housings provide superior dielectric strength, voltage insulation and durability
  • OPTIMAL PERFORMANCE: Precision coil windings and laminations maximize outputs, custom NGK ASIC chipset optimizes efficiency, prevents component damage
  • EASE OF INSTALLATION: NGK Ignition Coils include ignition control module, premium high temperature coil boot, and jumper harnesses where required
  • THE NGK DIFFERENCE: Featuring superior materials and design enhancements.
  • EXTENSIVE TESTING: NGK ignition coils must pass extreme testing during manufacturing to ensure the highest quality and durability standards are met
  • PRODUCT ENGINEERING: Advanced flow and stress modeling systems preemptively identify and avoid common failure points found in OE and competitor coils
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MSD Ignition – Coil; Pro Power; GM LS2/3/4/7/9; 05-13 Single (Part No.8287)

Coil; Pro Power; GM LS2/3/4/7/9; 05-13 Single

from

$169.99
MSD ignition’s Multiple Spark Coils (MSC) will fit in place of the stock gen-III GM coils and connect directly to the factory connectors. Once installed, you’ll have the power and performance of higher energy sparks, crowned with MSD’s multiple spark discharge. Increased spark energy and voltage, along with multiple spark capabilities, help improve the combustion process of the fuel mixture to create an efficient burn. This results in improved throttle response, smooth idle and quick starts, plus increased high rpm performance. The MSC delivers up to three times the current of the stock coils. Plus, the coils fire multiple times.

Product Features:
  • Multiple Sparks At Idle RPM
  • Improved Spark Energy And Voltage Output
  • Patented Winding Design and Materials
  • Direct Bolt-In to Factory Connectors
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GM Genuine Parts – Spark Plug Wire (Part No.12716289)

Spark Plug Wire

from

$17.99
GM Genuine Parts Genuine GM Spark Plug Wires are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These wires are a single wire encased in an insulating material, and contains connectors and insulating boots. It transfers high voltage pulses between the voltage source, the distributor, and your vehicle’s spark plug. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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ACDelco – Spark Plug Wire (Part No.350R)

Spark Plug Wire

from

$24.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Specific FitSpark Plug Wire (Part No.349V)

Specific FitSpark Plug Wire

from

$19.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Spark Plug Wire Set (Part No.356F)

Spark Plug Wire Set

from

$28.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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NGK – Metal Glow Plug: Advanced Quick Glow Type, Y1033AS (Part No.90046)

Metal Glow Plug: Advanced Quick Glow Type, Y1033AS

from

$18.99
NGK metal glow plugs are trusted by OEM diesel engine manufacturers around the world to perform under the harshest conditions. NGK metal glow plugs are equipped with a heating coil in a glow rod made of heat-resistant magnesium oxide between the heating and regulating coils. Magnesium oxide is an outstanding thermal conductor (quickly dissipating heat), while protecting the heating coils from vibration and shock. NGK metal glow plugs feature excellent gas-tight sealing qualities that deliver superior electrical insulation and protection against combustion gas. NGKs metal composition helps reduce carbon accumulation to prevent short circuits, while the unique shell design provides excellent heat transfer.

Product Features:
  • ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction metal glow plug
  • SUPERIOR DURABILITY: Metal glow plugs are designed to withstand thermal shock due to quick changes in temperature
  • FAST HEATING PERFORMANCE: Fast heat up enables smooth engine starts even in extreme weather conditions
  • CLEAN PERFORMANCE: Constant afterglow temperature minimize noxious pollutants
  • RECOMMENDED USAGE: Best for diesel engines with OE metal glow plugs
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GM Genuine Parts – Glow Plug (Part No.63G)

Glow Plug

from

$23.99
GM Genuine Parts Diesel Glow Plugs are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Autolite – Diesel Engine Glow Plug: High Intensity Concentrated Heat, Reliable Starts (Part No.1113)

Diesel Engine  Glow Plug: High Intensity Concentrated Heat, Reliable Starts

from

$19.99
Starting a diesel engine? Check out Autolite glow plugs. They’re dependable and long-lasting, the perfect plug for a variety of diesel applications.

Product Features:
  • Diesel engines depend on high heat in the combustion chamber to ignite the fuel. When you cold start a diesel engine, there isn’t enough heat to ignite. Glow plug warms the combustion chamber to start the fuel ignition.
  • These glow plugs fit a variety of diesel applications. If you’re experiencing problems starting your diesel engine, it may have burnt out glow plugs.
  • Reaches temperatures hot enough to start in 30 seconds or less
  • For dependability and long-lasting performance, use Autolite glow plugs
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GM Genuine Parts – Glow Plug (Part No.62G)

Glow Plug

from

$19.99
GM Genuine Parts Diesel Glow Plugs are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Motorcraft – Spark Plug (AGSF52C) (Part No.SP-442)

Spark Plug (AGSF52C)

from

$3.29
Motorcraft Spark Plugs are original equipment on Ford Motor Company vehicles engineered to meet strict Ford engineering standards to provide original equipment performance and reliability. Delivering performance, reliability and confidence, Motorcraft spa

Product Features:
  • Motorcraft spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption and optimize emissions.
  • Backed by Motorcraft’s Service Parts Warranty
  • Exact fit for Ford, Lincoln and Mercury vehicles
  • Resistant to oxidation and arc erosion.
  • Multi-rib insulator protects against misfire.
  • Service intervals of up to 100,000 miles.
  • Motorcraft Spark Plugs are designed with high quality materials to provide reliable performance for almost any application.
  • Motorcraft Spark Plugs are what was in the vehicle when it was manufactured
  • Motorcraft ignition components help prevent false check engine lights.
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Champion – Iridium Spark Plug: Maximum Performance, OE Replacement, RS12WMPB4 (Part No.9405)

Iridium Spark Plug: Maximum Performance, OE Replacement, RS12WMPB4

from

$11.49
Champion® Iridium – the ultimate element. This spark plug’s fine-wire iridium center and platinum ground electrodes provide the sharpest spark focus for maximum performance.

Product Features:
  • Champion Iridium – Maximum Performance. Premium Spark Plug
  • Iridium center electrode delivers maximum life
  • Fine-wire center electrode and V-trimmed for greater ignitability
  • V-trimmed ground electrode promotes sharper spark focus
  • Maintains stable operating temperature under all engine loads
  • Heat-Active┐ alloy allows electrodes to reach optimal temperature quickly
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ACDelco – Professional RapidFire Performance Platinum Spark Plug (Part No.F1000575798ACD)

Professional RapidFire Performance Platinum Spark Plug

from

$9.57
Designed for today’s most popular autos, ACDelco’s RapidFire Platinum Spark Plugs fit engines using conventional plugs, as well as newer vehicles requiring platinum performance.

Product Features:
  • Ribless insulator that improves the plug-to-boot seal.
  • Tapered center wire electrode with a platinum pad reduces the firing diameter and helps improve the firing efficiency by concentrating and directing energy needed to fire the plug with less voltage.
  • Solid state suppressor with two-piece glass and brass seal helps reduce radio frequency interference, meters spark plug energy to help provide long electrode life and seals against compression leakage. When compared to conventional spark plugs:
  • Reduced sparking voltage.
  • Greater corrosion protection.
  • Longer life and improved efficiency.
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ACDelco – Professional Iridium Spark Plug (Part No.F1000465395ACD)

Professional Iridium Spark Plug

from

$17.47
Step up to the latest spark plug technology with ACDelco’s Professional Iridium Spark Plugs. Designed to last more than 100,000 miles in most applications, ACDelco Iridium Plugs are the ideal replacement for today’s top-performing vehicles.

Product Features:
  • Iridium is one of the hardest metals used in spark plugs today, which allows for smaller, more efficient electrode designs for improved cold starting and quicker acceleration.
  • Latest evolution in high-performance plug electrode material.
  • Improved cold-starting and acceleration characteristics.
  • Reduced ignition-system voltage demand saves wear and tear.
  • New-vehicle applications using iridium plugs continue to increase.
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Upgrade your 2021 GMC Sierra 2500 HD with Top-Quality Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2021 GMC Sierra 2500 HD, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Ignition and Tune-Up Products are key to keeping your Sierra 2500 HD functioning at its best. At Advance Auto Parts, we offer a wide selection of 26 Ignition and Tune-Up Products for the 2021 GMC Sierra 2500 HD, designed to meet your needs without breaking the bank. From Ignition Switch replacements to Ignition Coils and Boots upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Ignition and Tune-Up Products for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Ignition and Tune-Up Products for your 2021 GMC Sierra 2500 HD at great prices. Our Ignition and Tune-Up Products inventory for this model ranges from just $6.49 to $137.99, with an average price of $40.54. Our 26 Ignition and Tune-Up Products in stock come from 11 trusted brands, so you’re sure to find the right part for your 2021 GMC Sierra 2500 HD without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2021 GMC Sierra 2500 HD, we stock popular OEM and aftermarket Ignition and Tune-Up Products from top names like NGK, Autolite, E3, and more. NGK Ignition and Tune-Up Products start at just $8.29 and boast an impressive 5 stars average rating from customers. Autolite and E3 also bring quality to the table, with Ignition and Tune-Up Products available starting at $6.49, and at an average 5 stars rating. With 1,244 customer reviews and counting, our 2021 GMC Sierra 2500 HD Ignition and Tune-Up Products have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Ignition and Tune-Up Product upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 GMC Sierra 2500 HD is always ready to roll. We’re committed to providing you with everything you need to keep your Sierra 2500 HD in top shape, all in one place. Start shopping confidently below for your 2021 GMC Sierra 2500 HD!

Best-Selling Ignition Switches for 2021 GMC Sierra 2500 HDs

Enhance the driving experience in your GMC with 2 quality Ignition Switch components, starting at $36.99.

Carquest Premium – Ignition Switch (Part No.CSA2665)

Ignition Switch

from

$61.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
See More

Carquest Premium – Ignition Switch (Part No.CSC5038)

Ignition Switch

from

$36.99
Ignition Switch

Most Popular 2021 GMC Sierra 2500 HD Ignition Coils and Boots

Customize your GMC with 5 Ignition Coils and Boots products like Ignition Coils, all priced under $137.99.

Carquest Premium – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.EBA1147)

Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece

from

$77.99
Carquest Premium ignition coils meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coils are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coils with an industry-leading warranty. Carquest Premium ignition coils are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • 100% pure copper precision-wound windings increase coil life and ensure reliability and maximum coil output when needed.
  • Highly conductive aluminum alloy secondary terminal guarantees secondary coil terminals will not oxidize (rust), will provide excellent conductivity, extended coil life and will not cause excessive stress on the primary control circuit.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure confidence and product reliability, every time.
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NGK – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.48881)

Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece

from

$137.99
NGK ignition coils are manufactured to meet or exceed OE standards for the highest durability and operational performance, so they can be installed with confidence. NGK and their family of automotive products have over 80 year’s experience and are driven by extreme dedication to innovation, performance and quality. Developed and rigorously tested in our ISO 17025 accredited test lab under the most extreme conditions, NGK’s coil designs will outperform all others – far beyond operational environments a vehicle would actually experience

Product Features:
  • OE QUALITY: Vacuum-sealed premium epoxy resin and thermoplastic coil housings provide superior dielectric strength, voltage insulation and durability
  • OPTIMAL PERFORMANCE: Precision coil windings and laminations maximize outputs, custom NGK ASIC chipset optimizes efficiency, prevents component damage
  • EASE OF INSTALLATION: NGK Ignition Coils include ignition control module, premium high temperature coil boot, and jumper harnesses where required
  • THE NGK DIFFERENCE: Featuring superior materials and design enhancements.
  • EXTENSIVE TESTING: NGK ignition coils must pass extreme testing during manufacturing to ensure the highest quality and durability standards are met
  • PRODUCT ENGINEERING: Advanced flow and stress modeling systems preemptively identify and avoid common failure points found in OE and competitor coils
See More

Carquest Premium – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.EBA1102)

Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece

from

$61.99
Carquest Premium ignition coils meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coils are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coils with an industry-leading warranty. Carquest Premium ignition coils are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • 100% pure copper precision-wound windings increase coil life and ensure reliability and maximum coil output when needed.
  • Highly conductive aluminum alloy secondary terminal guarantees secondary coil terminals will not oxidize (rust), will provide excellent conductivity, extended coil life and will not cause excessive stress on the primary control circuit.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure confidence and product reliability, every time.
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Delphi – Ignition Coil (Part No.GN10165)

Ignition Coil

from

$91.99
Delphi OE technology ignition products are validated to match the vehicles system; OE quality replacement parts for the right fit , form and function; Delphi coils provide OE performance, durability and electromagnetic capacity level requirements.

Product Features:
  • Delphi coils provide OE performance, durability and electromagnetic capacity level requirements
  • Delphi ignition coils are designed to operate as part of an integral engine management system to insert power into spark plugs and ensure fast starts; consistent engine performance and optimized fuel efficiency
  • Delphi uses winding process techniques to control the length of wire between adjacent windings; that’s important since more length means greater voltage differences and can create more pressure that could break down the insulation and wire coating
  • We back our ignition coil design with proven materials, such as high quality wires and wire coating that resists the cracks, pin holes and imperfections that most often lead to failure issues
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Autopart International Inc – Ignition Coil (Part No.F30001982223API)

Ignition Coil

from

$50.43
Ignition Coil

Top Picks for 2021 GMC Sierra 2500 HD Spark Plugs

Upgrade GMC Sierra 2500 HDs with top-quality Spark Plugs parts, including 12 OEM and aftermarket selections for your 2021 model.

NGK – Ruthenium HX High Ignitability Spark Plug: DFE Tip Design, LTR5AHX (Part No.90220)

Ruthenium HX High Ignitability Spark Plug: DFE Tip Design, LTR5AHX

from

$14.99
NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug; Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:
  • HIGH IGNITABILITY DOUBLE FINE ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with opposed fine wire platinum ground electrode
  • RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
  • PLATINUM PIN TYPE GROUND ELECTRODE: Provides more complete fuel burn, quicker throttle response, smoother idle and better cold starts
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modern vehicles using OE DFE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
  • Specialized OEM Tip Designs: Features patented DFE and PSPE tip designs for superior ignitability.
  • Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.
  • Advanced OE Technology: Created from advanced Original Equipment technology for modern vehicles.
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NGK – Iridium IX Spark Plug: Single Iridium Fine Wire, LTR5IX-11 (Part No.4344)

Iridium IX Spark Plug: Single Iridium Fine Wire, LTR5IX-11

from

$10.99
NGK Iridium IX spark plugs are specifically designed for the performance enthusiast. Iridium IX provides outstanding acceleration, high fuel efficiency and durability. NGK Iridium IX plugs offer extreme ignitability and exceptional anti-fouling. Tapered cut ground electrode provides improved starting, idling and throttle response. The Iridium fine wire center electrode’s durability is six times harder than platinum. Iridium alloy’s extremely high melting point is perfect for today’s engines. For even greater performance consider upgrading to an NGK Ruthenium HX plug.

Product Features:
  • SINGLE IRIDIUM TIP: Fine wire 0.6 millimeter iridium tip center electrode ensures high durability and a consistently stable spark
  • IRIDIUM ALLOY CENTER ELECTRODE: Iridium’s density (6x that of platinum) and extremely high melting point is perfect for modern high efficiency engines
  • TAPERED CUT GROUND ELECTRODE: Reduced quenching design produces outstanding ignitability, improved acceleration, fuel efficiency and durability
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modified or high performance applications, or as an upgrade to OE nickel alloy spark plugs
  • Outstanding Acceleration and High Fuel Efficiency: NGK Iridium IX spark plugs are engineered to deliver superior acceleration and enhance fuel efficiency, making them ideal for performance enthusiasts.
  • Extreme Ignitability and Anti-Fouling: These spark plugs offer exceptional ignitability and anti-fouling properties, ensuring reliable performance and longevity.
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E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.74)

DiamondFIRE Automotive Spark Plug: More Power, Saves Gas

from

$8.49
The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.74 is a 14mm, 1.000 reach plug with a taper seat. It fits a wide variety of late model applications, especially Ford applications. The automotive plugs have three legs securing the Diamond FIRE electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond FIRE side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:
  • E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
  • Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
  • Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
  • Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
  • E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
  • The Spark Plugs are pre-gapped at the factory and cannot be adjusted.
  • Enhanced Heat Transfer: Three legs securing the Diamond FIRE electrode to the shell ensure excellent heat transfer and create more turbulence in the cylinder.
  • Wide Compatibility: The E3.74 spark plug is a 14mm, 1.000 reach plug with a taper seat, fitting a wide variety of late model applications, especially Ford vehicles.
  • Eco-Friendly Performance: Proven to reduce fuel consumption and improve hydrocarbon emissions, contributing to a cleaner environment.
  • Long-Term Efficiency: The Diamond FIRE side wire is designed for long-term use, maintaining increased power and reduced fuel consumption over time.
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NGK – G-Power Spark Plug: Single Platinum Tip Design, LTR5GP (Part No.5019)

G-Power Spark Plug: Single Platinum Tip Design, LTR5GP

from

$8.29
NGK G-Power Platinum spark plugs are the best single platinum spark plugs at an economical price. G-Power plugs feature a fine wire platinum center electrode and a trapezoidal cut ground electrode that offers increased durability, improved fuel efficiency, lower emissions, faster starts and quicker acceleration over conventional nickel spark plugs. An excellent upgrade for vehicles which used nickel alloy spark plugs originally. For better performance consider upgrading to a NGK Iridium IX plug. For even greater performance consider upgrading to a NGK RUTHENIUM HX plug.

Product Features:
  • SINGLE PLATINUM TIP: Fine wire 0.6 millimeter platinum tip center electrode ensures improved durability and a consistently stable spark
  • PLATINUM ALLOY: G-Power platinum provides exceptional value with increased performance and longer service intervals than factory nickel plugs
  • TRAPEZOIDAL CUT GROUND ELECTRODE: Reduces quenching design produces improved ignitability and performance
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • COLD-ROLLED THREADS: Prevents cross-threading and damage to cylinder heads
  • RECOMMENDED USAGE: Lower cost alternative to double precious metal spark plugs or as an upgrade to OE nickel alloy spark plugs
  • Enhanced Vehicle Performance: Experience faster starts and quicker acceleration compared to conventional nickel spark plugs, making it an excellent upgrade for vehicles originally using nickel alloy spark plugs.
  • Economical Upgrade: NGK G-Power Platinum spark plugs provide a cost-effective solution for upgrading your vehicle’s spark plugs without compromising on quality.
  • Compatibility and Versatility: Ideal for a wide range of vehicles, these spark plugs are a perfect fit for those looking to replace their nickel alloy spark plugs with a more durable and efficient option.
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Autolite Iridium – Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition (Part No.XP6043)

Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition

from

$9.99
Our best spark plug! Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.

Product Features:
  • 0.6 mm finewire design improves ignitability
  • Patented V-trimmed platinum sidewire technology resists wear
  • OE equivalent design is engineered for every engine
  • Designed for better overall durability with virtually no gap erosion
  • Double Iridium-Enhanced Alloy Technology Center Electrode: Offers improved durability and wear resistance for a longer-lasting spark plug.
  • Engineered in the USA: Designed with over 100 years of Autolite’s engineering experience for superior quality and performance.
  • Proven Track Record: Autolite has sold over 11 billion spark plugs, showcasing a legacy of reliability and trust.
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Autolite Iridium – Iridium Ultra Finewire Spark Plug: Optimal Performance, Durability, Ignitability (Part No.AI6043)

Iridium Ultra Finewire Spark Plug: Optimal Performance, Durability, Ignitability

from

$10.99
Autolite Iridium Ultra Laser Finewire Spark Plugs are one of our brand’s most technologically advanced products. These spark plugs provide superior durability, more focused ignition with better overall ignitability for optimum performance. Autolite Spark Plugs are the best alternative to OE spark plugs, offering OE fit form and function supporting all foreign and domestic makes and models at a value price. Autolite provides the automotive aftermarket and original equipment manufacturers with the highest quality ignition products and is the leading supplier of spark plugs in the world.

Product Features:
  • Autolite Iridium Ultra is an engineered OE replacement iridium spark plug.
  • A laser-welded 0.5mm pure iridium finewire center electrode provides optimal fuel efficiency, acceleration and focused ignitability.
  • Nickel-plated shell to resist corrosion.
  • High-alumina ceramic insulator for increased strength.
  • Laser welded 0.5mm Iridium finewire center electrode.
  • Proprietary platinum sidewire technology.
  • Superior Durability: Autolite Iridium Ultra Laser Finewire Spark Plugs are designed to last longer, providing extended service life compared to standard spark plugs.
  • OE Fit and Function: Autolite Spark Plugs are the best alternative to original equipment (OE) spark plugs, offering perfect fit, form, and function for all foreign and domestic makes and models.
  • High-Quality Construction: As a leading supplier of spark plugs globally, Autolite ensures the highest quality ignition products for both the automotive aftermarket and original equipment manufacturers.
  • Value Pricing: Despite their advanced technology and superior performance, Autolite Iridium Ultra Laser Finewire Spark Plugs are available at a value price, making them an economical choice for vehicle maintenance.
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Autolite – Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life (Part No.APP6043)

Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life

from

$6.49
With over 100 years of engineering expertise and more than 11 billion plugs sold, Autolite delivers exceptional quality. Designed and engineered in the USA, these spark plugs feature platinum-to-platinum firing, virtually eliminating gap erosion and reducing misfires. The OE design and full-platinum tips on both the center and side electrodes optimize engine performance for a longer life and improved fuel economy. The platinum ball welding process ensures a consistent point of contact for enhanced adhesion, making these spark plugs a reliable choice for superior durability.

Product Features:
  • Works to optimize engine performance for a longer life and improved fuel economy
  • OE design
  • Full-platinum tips; platinum on both the center and side electrodes to promote reduced gap wear
  • Platinum ball welding process provides a consistent point of contact for enhanced adhesion
  • Engineered in the USA: Designed and engineered in the USA, leveraging over 100 years of Autolite’s engineering expertise and quality assurance.
  • Proven Quality: With over 11 billion spark plugs sold, Autolite delivers exceptional quality and reliability, making it a trusted choice for automotive enthusiasts and professionals.
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NGK – OE Series Laser Iridium Spark Plug: Fine Wire Tip Design, ILTR5E11 (Part No.91418)

OE Series Laser Iridium Spark Plug: Fine Wire Tip Design, ILTR5E11

from

$14.99
NGK Laser Iridium spark plugs offer the best combination of performance and longevity. Engineered specifically for OE applications, Laser Iridium spark plugs are tested to the highest standards to ensure quality and durability. Iridium tipped center electrode provides durability six times harder than platinum. NGKs high grade pure alumina ceramic and 98 percent pure copper core prevents the spark plug from overheating while providing reliable starts. Most Laser Iridium spark plugs feature a platinum pad on the ground electrode for even wear in distributorless ignition systems.

Product Features:
  • ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction fine wire iridium alloy center electrode provides consistent performance
  • IRIDIUM ALLOY CENTER ELECTRODE: Iridium’s density (6x that of platinum) and extremely high melting point is perfect for modern high efficiency engines
  • PLATINUM TIP GROUND ELECTRODE: Unless OE specified, platinum protection at the ground electrode provides excellent ignitability and service life
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Best for vehicles with OE fine wire iridium alloy plugs
  • Superior Durability: The iridium-tipped center electrode is six times harder than platinum, ensuring long-lasting performance.
  • High-Quality Materials: Constructed with high-grade pure alumina ceramic and a 98% pure copper core to prevent overheating and ensure reliable starts.
  • OE Application Specific: Engineered specifically for Original Equipment (OE) applications, meeting the highest standards for quality and durability.
  • Fine Wire Tip Design: The fine wire tip design of the ILTR5E11 model ensures efficient and consistent spark delivery.
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GM Genuine Parts – Spark Plug Wire (Part No.12716289)

Spark Plug Wire

from

$17.99
GM Genuine Parts Genuine GM Spark Plug Wires are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These wires are a single wire encased in an insulating material, and contains connectors and insulating boots. It transfers high voltage pulses between the voltage source, the distributor, and your vehicle’s spark plug. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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ACDelco – Professional Iridium Spark Plug (Part No.F1000465395ACD)

Professional Iridium Spark Plug

from

$17.47
Step up to the latest spark plug technology with ACDelco’s Professional Iridium Spark Plugs. Designed to last more than 100,000 miles in most applications, ACDelco Iridium Plugs are the ideal replacement for today’s top-performing vehicles.

Product Features:
  • Iridium is one of the hardest metals used in spark plugs today, which allows for smaller, more efficient electrode designs for improved cold starting and quicker acceleration.
  • Latest evolution in high-performance plug electrode material.
  • Improved cold-starting and acceleration characteristics.
  • Reduced ignition-system voltage demand saves wear and tear.
  • New-vehicle applications using iridium plugs continue to increase.
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DENSO – Iridium Power Spark Plug (Part No.F1000177171ND)

Iridium Power Spark Plug

from

$13.24
DENSO Iridium Power spark plugs represent a performance breakthrough. The laser-welded center electrode is only 0.4mm in diameter – the slimmest iridium electrode in the industry. The taper-cut side electrode complements the design, delivering reliable spark energy under the most gruelling pressures and temperatures. DENSO engineers used the power of this miraculous metal to produce an iridium center electrode that is only 0.4mm in diameter. With its superior thermal qualities, this whisker-fine electrode is capable of taking the most extreme heat and punishment. This breakthrough was matched to one of DENSO’s most famous innovations, the patented U-Groove ground electrode. The combination of these two features resulted in the Iridium Power® plug, one of the most advanced and innovative spark plugs on the market.

Product Features:
  • Tapered cut, U-Groove ground electrode
  • 0.4mm iridium center electrode
  • 360-degree laser welding assembly process
  • Required ignition voltage reduced
  • Unsurpassed center electrode durability
  • Available for many performance and power sports applications, including Corvette, Viper, and Harley-Davidson The Iridium Power plug delivers greater spark energy while demanding significantly less secondary required voltage from the ignition system.
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DENSO – Iridium Long-Life Spark Plug: OE Performance, last 100K+ Miles, ZTJ16VR10 (Part No.3539)

Iridium Long-Life Spark Plug:  OE Performance, last 100K+ Miles, ZTJ16VR10

from

$9.99
Manufactured to the strictest OE performance, durability and emissions standards.

Product Features:
  • Latest OE technology with DENSO’s patented Iridium Alloy (90% Ir) and fine wire center electrode
  • Platinum ground electrode for extended life
  • DENSO Patented 360 degree laser welding process: Ensuring exceptional quality bond and structural strength with the Iridium Center Electrode
  • Sustained spark performance over 100,000 miles
  • Lasts up to three times as long as conventional plugs
  • Endures extreme temperatures greater than 4,000 degrees F associated with high-performance ignition and special fuel systems
  • Iridium Long Life
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In-Demand Ignition Wires for 2021 GMC Sierra 2500 HDs

Select from 3 premium Ignition Wires parts for your 2021 GMC Sierra 2500 HD, with prices ranging from $65.22 to $89.99.

Karlyn – Ignition Wire Set (Part No.F10202140926KAR)

Ignition Wire Set

from

$73.47
The Karlyn Ignition Wire Set incorporates two layers of high grade silicone for superior heat and voltage protection. The double extruded Silicone-over-Silicone wire contains 19 strands of tinned copper core which provides super conductivity and corrosion resistance.

Product Features:
  • OE-Equivalent.
  • OEM style connectors for easy Installation.
  • Resistant to high temperatures, corrosion and vibration.
  • Ignition noise suppressed.
  • Includes O.E. Type Connectors, Looms, Sensors and Harness Clips when required
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GM Genuine Parts – Sparkplug Wire Kit (Part No.19431551)

Sparkplug Wire Kit

from

$89.99
Maintain your Chevrolet, Buick, GMC, or Cadillac vehicle with a Genuine GM Spark Plug Wire Set. This set consists of a group of wires encased in an insulating material, as well as connectors and insulating boots. They transfer high voltage pulses between the voltage source, the distributor, and your vehicle’s spark plug. Only Genuine GM Parts are tested to meet GM Original Equipment standards and are designed specifically to fit your vehicle.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • Designed, engineered, tested, and warranted for GM vehicles
  • Precise fit for ease of installation
  • For proper installation, locate your nearest GM dealer, independent service center, or body shop
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Autopart International Inc – Ignition Wire Set (Part No.F10202047981API)

Ignition Wire Set

from

$65.22
Ignition Wire Set

Most Sold 2021 GMC Sierra 2500 HD Glow Plugs

Explore our best-selling GMC parts for the 2021 Sierra 2500 HD among 1 OEM and aftermarket options starting from $34.99.

GM Genuine Parts – Glow Plug (Part No.68G)

Glow Plug

from

$34.99
GM Genuine Parts Diesel Glow Plugs are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Top-Rated Ignition and Tune-Up Products Brands For Your 2021 GMC Sierra 2500 HD

Shop for the best-rated brands offering Ignition and Tune-Up Products and other products for your 2021 GMC Sierra 2500 HDs. Below you’ll find some of our best rated Ignition and Tune-Up Products from NGK, Autolite, and E3, and more. Ignition and Tune-Up Products from these brands that fit a 2021 Sierra 2500 HD start at just $6.49 and are rated as high as 5 stars. OEM and aftermarket Ignition and Tune-Up Products don’t get more top quality, durable, and affordable than from the brands below.

Popular NGK 2021 GMC Sierra 2500 HD Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2021 GMC Sierra 2500 HD, using quality Ignition and Tune-Up Products is essential to ensure durability and a perfect fit. NGK ticks all of those boxes. We offer a wide selection of NGK Ignition and Tune-Up Products, specifically designed for the 2021 GMC Sierra 2500 HD. With over 5 NGK brand Ignition and Tune-Up Products in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $8.29, with an average price of just $37.45. Plus, with over 81 customer reviews and an average rating of 5 stars, you can trust that our NGK Ignition and Tune-Up Products will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

Ruthenium HX High Ignitability Spark Plug: DFE Tip Design, LTR5AHX
from
$14.99

(1)

Ruthenium HX High Ignitability Spark Plug: DFE Tip Design, LTR5AHX

“really good spark plugs and provides the best for money option if your your vehicle to last a long time.”

OE Series Laser Iridium Spark Plug: Fine Wire Tip Design, ILTR5E11
from
$14.99
This product is not rated

OE Series Laser Iridium Spark Plug: Fine Wire Tip Design, ILTR5E11

“”

Popular Autolite 2021 GMC Sierra 2500 HD Ignition and Tune-Up Products

Autolite auto parts is one of the highest quality Ignition and Tune-Up Product brands in the market. Any 2021 GMC Sierra 2500 HD owner should feel confident when installing genuine Autolite parts in their vehicle. To ensure the best fit and performance for your 2021 Sierra 2500 HD, Advance Auto Parts carries a full inventory of 3 Autolite Ignition and Tune-Up Products. Plus you will be keeping your GMC in peak condition while saving money because prices on these Autolite Ignition and Tune-Up Products range from $6.49 to $10.99, plus, with more than 8 customer reviews and an impressive 5 stars average rating, you can be confident the Fram Ignition and Tune-Up Products below will deliver on both quality and value.

Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition
from
$9.99

(8)

Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition

“Used these as replacements in my 2015 Silverado 5.3L. Plugs work well, engine runs smooth. Nice replacement.”

FAQs for 2021 GMC Sierra 2500 HD Ignition and Tune-Up Products

Which Ignition and Tune-Up Products are best-sellers for 2021 GMC Sierra 2500 HDs?

Out of 26 Ignition and Tune-Up Products that fit 2021 GMC Sierra 2500 HDs, the following parts are the top sellers:

What’s the price range for 2021 GMC Sierra 2500 HD Ignition and Tune-Up Products?

Ignition and Tune-Up Product prices for the 2021 GMC Sierra 2500 HD start at $6.49 and go up to $137.99 for the most premium parts.

What’s the average price of a Ignition and Tune-Up Product for a 2021 GMC Sierra 2500 HD?

The average price for Ignition and Tune-Up Products for the 2021 GMC Sierra 2500 HD is $40.54. Keep in mind the variety of part types within our Ignition and Tune-Up Product category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Ignition and Tune-Up Products for other GMC Sierra 2500 HD model years?

Yes, we currently carry Ignition and Tune-Up Products for 24 model years of GMC Sierra 2500 HDs between 2001 and 2025. Ignition and Tune-Up Products are bought most frequently for the following model years: 2023, 2022, 2020, 2019, 2018, 2017, 2016, 2015, and 2014.

What are the cheapest Ignition and Tune-Up Products for my 2021 GMC Sierra 2500 HD?

What are the top-rated Ignition and Tune-Up Products that fit the 2021 GMC Sierra 2500 HD?

Out of 1,244 reviews by customers, our 2021 GMC Sierra 2500 HD Ignition and Tune-Up Products have an average customer rating of . These are some of the highest-rated Ignition and Tune-Up Product types for the 2021 GMC Sierra 2500 HD and their top-rated products:

What types of Ignition and Tune-Up Products do you sell for my 2021 GMC Sierra 2500 HD?

As of 2/5/25, these are some of the most in-demand types of Ignition and Tune-Up Products for a 2021 GMC Sierra 2500 HD:

Can I get help with 2021 GMC Sierra 2500 HD Ignition and Tune-Up Product orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Ignition and Tune-Up Products and more.

What is your return policy for GMC Sierra 2500 HD Ignition and Tune-Up Products?

Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Ignition and Tune-Up Products and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.