2021 GMC Sierra 2500 HD Fuel and Emissions Systems

Essential 2021 GMC Sierra 2500 HD Fuel and Emissions Systems

Dorman – Help – Fuel Tank Strap Hardware Kit (Part No.55157)

Fuel Tank Strap Hardware Kit

from

$12.49
This fuel tank attaching hardware is designed to match the fit and function of the original hardware on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this fuel tank attaching hardware is designed to match the fit and function of the original hardware on specified vehicles
  • Recommended replacement for the original hardware when servicing or replacing the fuel tank
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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ACDelco – GM Original Equipment Air Mass Sensor (Part No.B3150756035ACD)

GM Original Equipment Air Mass Sensor

from

$165.03
An ACDelco GM Original Equipment Air Mass Sensor is a key part of the engine management system, and is a GM-recommended replacement for your vehicle’s original component. The Air Mass Sensor measures the amount of air entering the engine so that the engine control module can determine the amount of fuel to inject. This ensures the most efficient air/fuel mixture for the best fuel economy and power, while reducing harmful exhaust emissions. This original equipment mass air flow sensor has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Measure the amount of air entering the engine so that the engine control module can determine the amount of fuel to inject
  • Undergo the same stringent testing process as the original part
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Felpro – Fuel Injection Throttle Body Mounting Gasket (Part No.61469)

Fuel Injection Throttle Body Mounting Gasket

from

$13.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
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ACDelco – Fuel Tank Pressure Sensor (Part No.13502903)

Fuel Tank Pressure Sensor

from

$78.99
ACDelco GM Original Equipment Fuel Tank Pressure Sensors are GM-recommended replacements for your vehicle’s original components. These sensors help measure pressure changes within your vehicle’s fuel tank. They also help alert your vehicle’s engine management computer if a leak occurs in your vehicle’s fuel system. These original equipment sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Help measure pressure changes within fuel tank
  • Help alert engine management computer if a leak occurs in fuel system
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Fuel Injection Throttle Control Actuator Module (Part No.12588923)

Fuel Injection Throttle Control Actuator Module

from

$309.99
GM Genuine Parts Fuel Injection Throttle Control Actuator Modules are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These modules are electrically operated motor assemblies that control throttle plates. They receive an electrical signal from the engine control module and open throttle plates based on input from the accelerator pedal module. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Dorman – Fuel Pump Lock Ring (Part No.579-102)

Fuel Pump Lock Ring

from

$17.79
A recommended replacement whenever the sending unit is serviced, this fuel tank lock ring is a direct match for the original part. Designed for a secure fit, it’s manufactured from durable materials for reliable service.

Product Features:
  • Direct replacement – this fuel tank lock ring matches the fit, function and performance of the original part
  • Ideal solution – recommended for replacement whenever the sending unit is serviced to ensure a secure connection to the fuel tank
  • Durable construction – manufactured from quality materials for superior service and reliability
  • Trustworthy design – backed by a team of product designers and engineers with over 100 years of automotive aftermarket experience
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Carquest Premium – Vapor Canister Purge Solenoid (Part No.CPC1019)

Vapor Canister Purge Solenoid

from

$44.99
Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Carquest Premium – Vapor Canister Purge Solenoid (Part No.CPA3001)

Vapor Canister Purge Solenoid

from

$46.49
Vapor Canister Purge Solenoid

Carquest Premium – Ambient Air Temperature Sensor (Part No.WTA1034)

Ambient Air Temperature Sensor

from

$11.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Carquest Premium – Ambient Air Temperature Sensor (Part No.WTA1537)

Ambient Air Temperature Sensor

from

$10.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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GM Genuine Parts – Fuel Pump O-Ring (Part No.G41)

Fuel Pump O-Ring

from

$12.99
GM Genuine Parts Multi Purpose Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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MAHLE Original – Fuel Injector Seal Kit (Part No.GS33578A)

Fuel Injector Seal Kit

from

$67.99
MAHLE gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
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GM Genuine Parts – Fuel Injector O-Ring Kit with Washers (Part No.217-3438)

Fuel Injector O-Ring Kit with Washers

from

$28.49
GM Genuine Parts Fuel Injector Seal Kits are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help provide liquid-tight connections between the fuel injector and related components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps provide a seal to prevent fuel leaks
  • Helps seal combustion chamber from the elements
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Delphi – Fuel Tank Cleaning Kit (Part No.FC01)

Fuel Tank Cleaning Kit

from

$12.49
To perform a complete fuel pump replacement, clean the tank every time. Order the Delphi Fuel Tank Cleaning Kit (Part FC01). Remember, the original pump went into a clean fuel tank, to ensure the same level of performance, the new pump should too. 100 ye

Product Features:
  • Helps avoid premature fuel pump failure
  • Lint free towel included
  • Low suds formulation
  • Removes harmful contaminants from the fuel tank
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GM Genuine Parts – Fuel Filter Kit: Includes Seals & Filter (Part No.TP1015)

Fuel Filter Kit: Includes Seals & Filter

from

$44.99
Fuel Filter Kit

Product Features:
  • Helps prevents dirt, rust, and other fuel contaminants from entering the fuel delivery system
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – RELAY,PARK LP (Part No.D1777C)

RELAY,PARK LP

from

$11.49
GM Genuine Parts Wiring Relays are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These relays help connect or disconnect power to a vehicle accessory when it receives a low voltage signal from a switch. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps connect or disconnect power to vehicle accessories
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – Multi Purpose Relay (Part No.RAA2674)

Multi Purpose Relay

from

$9.99
Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Dorman – Fuel Tank O-Ring (Part No.911-245)

Fuel Tank O-Ring

from

$39.99
This fuel pump tank seal is designed to match the fit and function of the original seal on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this fuel pump tank seal is designed to match the fit and function of the original seal on specified vehicles
  • Restores functionality – reliable replacement for an original part that has failed due to fatigue or due for replacement during fuel pump tank service
  • Durable construction – recommended for replacement when the fuel pump or sensor is replaced
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Fuel Pump Gasket (Part No.911-572)

Fuel Pump Gasket

from

$14.49
This fuel pump tank seal is designed to match the fit and function of the original seal on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this fuel pump tank seal is designed to match the fit and function of the original seal on specified vehicles
  • Restores functionality – reliable replacement for an original part that has failed due to fatigue or due for replacement during fuel pump tank service
  • Durable construction – recommended for replacement when the fuel pump or sensor is replaced
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Carquest Premium – Manifold Absolute Pressure Sensor (Part No.WTA1591)

Manifold Absolute Pressure Sensor

from

$36.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Carquest Premium – Manifold Absolute Pressure Sensor (MAP) (Part No.ECA1298)

Manifold Absolute Pressure Sensor (MAP)

from

$61.99
CARQUEST MAP sensors are manufactured with critical OEM components to ensure that your engine runs efficiently to reach the best gas mileage on your vehicle.

Product Features:
  • CARQUEST MAP sensors connectors are exact OE fit to ensure the proper vacuum is maintained to prevent power loss and to minimize internal contamination.
  • CARQUEST MAP sensors utilize high temperature resistant seals. Damaged seals can directly impact the vehicles fuel-to-air ratio, making it less fuel efficient.
  • CARQUEST MAP sensors are 100% individually tested for all product functionalities including proper vacuum seal and electrical output.
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Carquest Premium – New MAP SENSOR (Part No.ECE1033)

New MAP SENSOR

from

$51.99
The Premium CarQuest Vehicle Solutions line is designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Relief Valve is used in the automotive air conditioning system to prevent unusual over-pressure that may cause damage to critical components within the system or to the system as a whole. By opening it’s valve when the system pressure exceeds the preset pressure levels and closing when the internal pressure decreases to the preset pressure levels, proper factory designated system pressures are maintained.

Product Features:
  • Made to OE spec to ensure a proper fit, form and function.
  • Sensors are engineered for precision performance, durability and a long service life.
  • All units are tested using advanced end-of-line testing equipment that pressurizes the A/C Pressure Relief Valve and checks functionality to ensure each A/C Pressure Relief Valve meets manufacturing specifications before packaging.
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ACDelco – Indirect Fuel Injector Assembly (Part No.12641278)

Indirect Fuel Injector Assembly

from

$236.99
ACDelco GM Original Equipment Hydrocarbon Injectors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.

Product Features:
  • This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
  • Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional
  • ACDelco GM Original Equipment parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Cardone – Fuel Injector (Part No.2J-101)

Fuel Injector

from

$545.99
CARDONE Remanufactured Fuel Injectors provide an alternative plug and play solution to fuel delivery for diesel applications. All units are flow tested and balanced and replaced with new O-rings and gaskets. Each unit retains OEM duty cycle and pulse width ensuring reliable performance. All units are built to meet or exceed OEM performance, providing a quality product both you and your vehicle can rely on.

Product Features:
  • All gaskets, O-rings and bearings are replaced 100% to ensure optimal performance
  • Each assembled unit is individually calibrated and tested to ensure it meets or exceeds O.E.M. form, fit and function
  • All components are renewed or replaced as necessary to ensure high quality and durability
  • When applicable, improvements based on typical failure modes of original units are incorporated into the design and manufacture of replacement component parts, which translates into longer service life and less down-time for the driver
  • Guaranteed fit and function
  • Meets or exceeds O.E.M. performance
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ACDelco – Sequential Multi-Port Fuel Injector Assembly (Part No.217-1621)

Sequential Multi-Port Fuel Injector Assembly

from

$138.99
ACDelco GM Original Equipment Fuel Injectors are electro-magnetic valves that meter fuel into the engine’s intake manifold or cylinders for combustion, and are GM-recommended replacements for your vehicle’s original components. The engine control module (ECM) operates the injector by applying an electric current to the injector solenoid winding, causing the needle valve to open, and allowing pressurized fuel to be atomized into the intake airstream. These original equipment fuel injectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
  • Atomizes fuel into the engine’s intake manifold or cylinders, as part of the fuel and engine management system
  • Allows for a quick throttle response
  • Assists in cold engine starts
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest – Fuel Injector (Part No.63877)

Fuel Injector

from

$464.99
High-quality products that meet OE appearance and performance to provide professional technicians and DIYers with a cost-effective solution.

Product Features:
  • Designed to OE standards for ease of installation
  • State-of-the-art designs that meet or exceed OE specifications
  • Top-of-the-line quality and performance
  • With industry leading expertise, when original equipment fails our products are designed to fix the inherent failure issues
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Carquest Premium – Remanufactured Fuel Injector (Part No.A211-2173)

Remanufactured Fuel Injector

from

$53.99
CARQUEST’S line of remanufactured OEM fuel injectors are remanufactured using a proven 15 step process at a state-of-the-art remanufacturing facility in the U.S.A. Each injector is 100% tested under multiple operating conditions to ensure each injector meets or exceeds OE specifications for flow rate, spray pattern, coil resistance, form, fit and function. Each injector includes new external seals and O-rings.

Product Features:
  • Each unit is 100% tested to OE specifications
  • Includes new O-rings and seals made of premium OE quality materials
  • Includes application specific technical bulletin, where applicable
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Carquest Premium – Remanufactured Diesel Fuel Injector (Part No.AD25023)

Remanufactured Diesel Fuel Injector

from

$275.99
CARQUEST premium remanufactured injectors are completely torn down, ultrasonically cleaned, inspected and remanufactured using premium components. Each injector is 100% tested on a sophisticated flow bench under multiple operating parameters to meet or exceed OE specifications.

Product Features:
  • Each unit is 100% tested to OE specifications
  • Includes 100% replacement of the fuel fitting, edge filter and retaining pin to ensure a leak-free connection
  • Includes 100% new stator solenoid to ensure precise fuel injection timing
  • Includes 100% replacement of nozzle to ensure accurate and precise injection under all operating parameters
  • Includes all new premium quality O-rings and seals
  • Includes copper combustion gasket
  • Includes application specific technical bulletin which highlights critical aspects of the job and offers technical tips for proper installation
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2021 GMC Sierra 2500 HD Fuel and Emissions Systems

You count on your 2021 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Fuel and Emissions Systems. With 26 Fuel and Emissions Systems ranging in price from $7.99 to $297.99, you’re sure to find everything you need for your 2021 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Fuel and Emissions Systems brand, we stock 8 different brands like GM Genuine, Dorman, and Carquest Premium. 2021 GMC Sierra 2500 HD Fuel and Emissions Systems start as low as $7.99!

One of the best ways to find top quality OEM or aftermarket Fuel and Emissions Systems is by asking professionals. Short of that, you can shop with confidence thanks to our 369 extensive product reviews on 2021 GMC Sierra 2500 HD Fuel and Emissions Systems. Some of the top-rated Fuel and Emissions Systems products we carry are RELAY,PARK LP with 4.5 stars.

Did we mention you can order your Fuel and Emissions Systems from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Fuel and Emissions Systems inventory for your 2021 GMC Sierra 2500 HD below to get started!

Top-Rated Fuel and Emissions Systems Brands For Your 2021 GMC Sierra 2500 HD

Trusted Fuel and Emissions Systems OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2021 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like GM Genuine, Dorman, Carquest Premium, and even more.

Popular Carquest Premium Fuel and Emissions Systems

You’ll find popular Carquest Premium brand products across Fuel Tanks. All are waiting to get your 2021 GMC Sierra 2500 HD back on the road. Some of the top-rated Carquest Premium products in these categories are:
Fuel Tank Lock Ring LO1582926
from $15.99
(5)
Fuel Tank Lock Ring LO1582926
Fuel Tank Lock Rings

Top-Rated Fuel and Emissions Systems


If are what you’re looking for, our inventory holds plenty. We stock brand Fuel and Emissions Systems for your 2021 GMC Sierra 2500 HD, and some of our most reviewed parts include:
Fuel Tank Strap Hardware Kit
from $12.49
(34)
Fuel Tank Strap Hardware Kit
Fuel Tank Attaching Hardware

FAQs for 2021 GMC Sierra 2500 HD Fuel and Emissions Systems

What are the most purchased Fuel and Emissions Systems for the 2021 GMC Sierra 2500 HD?

Out of 26 Fuel and Emissions Systems for the 2021 GMC Sierra 2500 HD, the most popular in our inventory are:
Fuel Filter Kit: Includes Seals & Filter
from $44.99
This product is not rated
Fuel Filter Kit: Includes Seals & Filter
Fuel Injection Filters
Fuel Tank Cleaning Kit
from $12.49
This product is not rated
Fuel Tank Cleaning Kit
Fuel Tank Cleaning Kits
Fuel Tank Lock Ring (Right)
from $12.99
This product is not rated
Fuel Tank Lock Ring (Right)
Fuel Tank Lock Rings

What are the top-rated 2021 GMC Sierra 2500 HD Fuel and Emissions Systems?

Top-rated Fuel and Emissions Systems for your 2021 GMC Sierra 2500 HD based on customer reviews/ratings are:
RELAY,PARK LP
from $11.49
(2)
RELAY,PARK LP
“Week of our first heatwave summer 2024, the part was needed for my ac. Located in another store, the staff made sure I had the part the same day for m”