2021 Ford E-450 Super Duty Ignition and Tune-Up Products

Below you will find various in-demand Ford Ignition and Tune-Up Products, components and accessories for your 2021 E-450 Super Duty. Advance Auto Parts has popular E-450 Super Duty parts like Ignition Coils and Boots, Ignition Switches, Ignition Boots and more. You’ll also find aftermarket and OEM Ignition and Tune-Up Products for other E-450 Super Duty model years including 2014, 2015, 2016, 2017, 2018, 2019, 2022, 2023, 2024 and more. Select a category of 2021 Ford E-450 Super Duty Ignition and Tune-Up Products below and start saving instantly.

Popular 2021 Ford E-450 Super Duty Ignition and Tune-Up Products Categories

Ignition Starter Switches

Essential Ignition and Tune-Up Products for 2021 Ford E-450 Super Duties

from

$5.49

NGK G-Power Platinum spark plugs are the best single platinum spark plugs at an economical price. G-Power plugs feature a fine wire platinum center electrode and a trapezoidal cut ground electrode that offers increased durability, improved fuel efficiency, lower emissions, faster starts and quicker acceleration over conventional nickel spark plugs. An excellent upgrade for vehicles which used nickel alloy spark plugs originally. For better performance consider upgrading to a NGK Iridium IX plug. For even greater performance consider upgrading to a NGK RUTHENIUM HX plug.

Product Features:

SINGLE PLATINUM TIP: Fine wire 0.6 millimeter platinum tip center electrode ensures improved durability and a consistently stable spark
PLATINUM ALLOY: G-Power platinum provides exceptional value with increased performance and longer service intervals than factory nickel plugs
TRAPEZOIDAL CUT GROUND ELECTRODE: Reduces quenching design produces improved ignitability and performance
SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
COLD-ROLLED THREADS: Prevents cross-threading and damage to cylinder heads
RECOMMENDED USAGE: Lower cost alternative to double precious metal spark plugs or as an upgrade to OE nickel alloy spark plugs

from

$11.99

ACDelco GM Original Equipment Iridium Spark Plugs are designed, engineered, and tested to rigorous standards, and are backed by General Motors. They are our latest in spark plug technology and an exact replacement for your vehicle’s original components. Iridium composition provides a high melting point and great strength, and provides excellent wear resistance and durability. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.

Product Features:

Iridium is the latest in spark plug technology and is an exact replacement for vehicles’ original components
Iridium composition provides a high melting point and great strength, helps to provide excellent wear resistance and durability
Iridium offers excellent engine idle stability, reliable cold starting, quick acceleration and smooth performance
Three Piece Fired in Suppressor seal meters spark energy for long electrode life, helps prevent combustion leakage and helps block radio frequencies that can affect vehicle electronics
Iridium plugs are laser-welded which provides precision welds, reduces excess debris and wear rate, thus increasing durability
Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional
ACDelco GM Original Equipment parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
GM regularly updates production and service part designs to integrate new materials and technologies

from

$6.99

The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.53 is a 14mm, .708 reach plug with a taper seat. It fits domestic applications, and is widely available in automotive retail stores. The automotive plugs have three legs securing the Diamond Fire electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond Fire side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:

E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
The Spark Plugs are pre-gapped at the factory and cannot be adjusted.

from

$10.99

Motorcraft Spark Plugs are original equipment on Ford Motor Company vehicles, engineered to meet strict Ford engineering standards for performance and reliability. These spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption, and optimize emissions. They are resistant to oxidation and arc erosion, feature a multi-rib insulator to protect against misfire, and offer service intervals of up to 100,000 miles. Backed by Motorcraft’s Service Parts Warranty, these spark plugs are an exact fit for Ford, Lincoln, and Mercury vehicles and are designed with high-quality materials to provide reliable performance for almost any application. Motorcraft ignition components also help prevent false check engine lights, ensuring your vehicle runs smoothly.

Product Features:

Motorcraft spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption and optimize emissions.
Backed by Motorcraft’s Service Parts Warranty
Exact fit for Ford, Lincoln and Mercury vehicles
Resistant to oxidation and arc erosion.
Multi-rib insulator protects against misfire.
Service intervals of up to 100,000 miles.
Motorcraft Spark Plugs are designed with high quality materials to provide reliable performance for almost any application.
Motorcraft Spark Plugs are what was in the vehicle when it was manufactured
Motorcraft ignition components help prevent false check engine lights.
Engineered for Ford Vehicles: Motorcraft High-Durability Spark Plugs are original equipment on Ford, Lincoln, and Mercury vehicles, ensuring a perfect fit and optimal performance.

from

$12.52

DENSO Iridium Power spark plugs represent a performance breakthrough. The laser-welded center electrode is only 0.4mm in diameter – the slimmest iridium electrode in the industry. The taper-cut side electrode complements the design, delivering reliable spark energy under the most gruelling pressures and temperatures. DENSO engineers used the power of this miraculous metal to produce an iridium center electrode that is only 0.4mm in diameter. With its superior thermal qualities, this whisker-fine electrode is capable of taking the most extreme heat and punishment. This breakthrough was matched to one of DENSO’s most famous innovations, the patented U-Groove ground electrode. The combination of these two features resulted in the Iridium Power® plug, one of the most advanced and innovative spark plugs on the market.

Product Features:

Tapered cut, U-Groove ground electrode
0.4mm iridium center electrode
360-degree laser welding assembly process
Required ignition voltage reduced
Unsurpassed center electrode durability
Available for many performance and power sports applications, including Corvette, Viper, and Harley-Davidson The Iridium Power plug delivers greater spark energy while demanding significantly less secondary required voltage from the ignition system.

from

$28.99

Bosch OE quality knock sensors for optimum engine protection and fuel consumption reduction up to 9%.

Product Features:

Bosch OE quality knock sensors for optimum engine protection
Bosch OE quality knock sensors increase torque up to 5%
Bosch OE quality knock sensors enable the use of multiple quality fuels with various anti-knock properties

from

$33.99

MotoRad Knock Sensors respond to a wide range of engine knock frequencies providing accurate engine condition to the ECM for optimal ignition timing. Highest quality piezoceramic element manufactured to tight tolerances for increased durability. All MotoRad Knock Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:

Precision piezoceramic element ensures accurate response to a wide range of engine vibrations
Manufactured using the highest quality OEM materials to ensure optimal performance and rugged durability
Designed to meet or exceed all OEM specifications in fit, form & function
Extensive product testing includes salt spray, high/low temperature impact, thermal cycling, vibration, drop among other tests, to ensure all sensors meet or exceed OEM specifications.

from

$23.99

Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

from

$36.99

Building upon a foundation of premium full-line products established under NGK ignition and NTK oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand: NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. NTK is the only OE supplier with a full-line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, NTK sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. NTK sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:

Reinforced and extra-strength components are used to reduce chance of part failure and prevent corrosion and moisture penetration. Mounting threads match OE for easy, worry free installation.
NTK’s Ignition Knock Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function to ensure proper ignition timing. This advanced technology is used for durability, drivability and fuel economy.
The Ignition Knock (Detonation) Sensor monitors vibrations caused by engine knock, or detonation, to alter the ignition timing and prevent detonation.

from

$61.30

The Forecast OE quality knock sensor is engineered to the exact specifications of the vehicle manufacturer to ensure the replacement sensor is the same in quality and function as the part installed as first equipment.

Product Features:

OEM quality direct fit application
Ground-isolated design with two-wire shielded harness helps protect the sensor signal from electro-magnetic interference (EMI)
Mounting hole is the same size as OE
Maintains OE specifications for frequency response

from

$21.79

Motorcraft Ignition Boots are engineered to provide original equipment performance and reliability. All Motorcraft parts undergo rigorous lab and real-world tests in order to meet strict Ford engineering standards. Terminal ends are designed to help ensure they do not separate from the cable under normal service conditions. High dialectic insulation helps maintain and control voltage delivery while reducing radio frequency interference. The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles

Product Features:

Backed by Motorcraft’s Service Parts Warranty
Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
Motorcraft ignition components help prevent false check engine lights.

from

$49.99

CARQUEST Premium coil on plug boots are engineered to restore ignition boot reliability and performance. We have OE design providing an exact direct fit for your application and the performance and durability meet or exceed OE requirements. It offers excellent heat resistance as well as maximum protection against spark loss. With durable silicone compound for resistance to high heat or abrasion.

Product Features:

Provides excellent heat resistance as well as maximum protection against spark loss.
Durable silicone compound for resistance to high heat or abrasion
Spring included with the coil boot
Design for direct compatibility
OE design provides an exact fit for your application
Multipack provides one time replace all COP for better deal

from

$51.99

Pc Cop Boots 97-11 Ford 8-Cyl

from

$7.49

NGK Coil on Plug Boots are built to stringent OEM tolerances, combining original equipment fit, design and outstanding durability. NGK Coil on Plug Boots are manufactured using only high temperature, premium silicone and always include any required internal springs and ferrite resistors for superior performance and RFI noise suppression. Bridging the important link between ignition coil and spark plug, COP boots should always be replaced with NGK Coil on Plug Boots at the time as changing spark plugs to prevent ignition problems such as flashover.

Product Features:

IMPROVED HIGH TEMPERATURE DESIGN: Solves melting problems for certain very high heat applications
OEM MATCHED: Includes all required internal springs and ferrite resistors for superior performance and RFI noise suppression

from

$70.99

CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

from

$119.98

Ignition Switch

from

$29.05

High-quality products that meet OE appearance and performance to provide professional technicians and DIYers with a cost-effective solution.

Product Features:

Designed to OE standards for ease of installation
Copper alloy conductors ensure superior electrical conductivity with low resistive losses
Our parts are 100% tested to verify both mechanical and electrical switching performance
Robust design and high grade materials meet the stringent demands of today’s service professional
BWD is a global manufacturer of original equipment ignition products, complete quality control is maintained through the manufacturing process from componentry to finished product

from

$83.99

The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:

Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.

from

$30.49

from

$47.99

The main device in any electrical circuit is a switch. In an electrical circuit a device is required to turn a component on or off when commanded by the operator, within the switch are contacts that will complete the electrical path to the load, or driven device. The operation of a switch may be manual from a person or could be electrical from some sort of controller or computer.

Product Features:

Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
Lead frame terminal size and location determined using image dimension measuring system or 3D laser scanner.
Where applicable electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.

from

$78.12

Ignition Switch

from

$117.99

Carquest Premium ignition coils meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coils are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coils with an industry-leading warranty. Carquest Premium ignition coils are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:

Built by IATF 16949 certified manufacturers for consistent durability
Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
Segmented secondary bobbins to distribute high voltage and prevent shorting
Extensive design validation testing to ensure long-lasting reliability
100% end-of-line tested to ensure proper performance
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$79.99

Delphi OE technology ignition products are validated to match the vehicles system; OE quality replacement parts for the right fit , form and function; Delphi coils provide OE performance, durability and electromagnetic capacity level requirements.

Product Features:

Delphi coils provide OE performance, durability and electromagnetic capacity level requirements
Delphi ignition coils are designed to operate as part of an integral engine management system to insert power into spark plugs and ensure fast starts; consistent engine performance and optimized fuel efficiency
Delphi uses winding process techniques to control the length of wire between adjacent windings; that’s important since more length means greater voltage differences and can create more pressure that could break down the insulation and wire coating
We back our ignition coil design with proven materials, such as high quality wires and wire coating that resists the cracks, pin holes and imperfections that most often lead to failure issues

from

$79.99

NGK ignition coils are manufactured to meet or exceed OE standards for the highest durability and operational performance, so they can be installed with confidence. NGK and their family of automotive products have over 80 year’s experience and are driven by extreme dedication to innovation, performance and quality. Developed and rigorously tested in our ISO 17025 accredited test lab under the most extreme conditions, NGK’s coil designs will outperform all others – far beyond operational environments a vehicle would actually experience

Product Features:

OE QUALITY: Vacuum-sealed premium epoxy resin and thermoplastic coil housings provide superior dielectric strength, voltage insulation and durability
OPTIMAL PERFORMANCE: Precision coil windings and laminations maximize outputs, custom NGK ASIC chipset optimizes efficiency, prevents component damage
EASE OF INSTALLATION: NGK Ignition Coils include ignition control module, premium high temperature coil boot, and jumper harnesses where required
THE NGK DIFFERENCE: Featuring superior materials and design enhancements.
EXTENSIVE TESTING: NGK ignition coils must pass extreme testing during manufacturing to ensure the highest quality and durability standards are met
PRODUCT ENGINEERING: Advanced flow and stress modeling systems preemptively identify and avoid common failure points found in OE and competitor coils

from

$24.99

ACCEL Super Coils feature advanced bobbin technology, highly specialized silicon magnetic steel cores, optimized windings, proper resistance and engineered turn ratios that deliver a high performance, quality coil. Specialized high temperature epoxy resists shock and vibration, while increasing thermal conductivity. These are direct improved performance replacements for OEM coils.

Product Features:

Specialized silicone magnetic steel cores are surrounded by precision wrapped windings using advanced bobbin technology which helps maintain the proper resistance and turn ratios necessary to deliver improved performance spark
Advanced Bobbin Technology
Direct Plug In Replacement results in a Direct OE Fit
OBD ll Safe, so you won’t be throwing codes, just sparks
Standard Motor Products SMP Fd-503
MSD 8242 82428
Resists Shock And Vibration
Resists Corrosion

from

$299.99

Carquest Premium ignition coil sets meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coil sets are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coil sets with an industry-leading warranty. Carquest Premium ignition coil sets are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:

Built by IATF 16949 certified manufacturers for consistent durability
Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
Segmented secondary bobbins to distribute high voltage and prevent shorting
Extensive design validation testing to ensure long-lasting reliability
100% end-of-line tested to ensure proper performance
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$344.99

Built by IATF 16949 certified manufacturers for consistent durability
Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
Segmented secondary bobbins to distribute high voltage and prevent shorting
Extensive design validation testing to ensure long-lasting reliability
100% end-of-line tested to ensure proper performance
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$59.05

Driveworks offers a line of aftermarket parts and accessories that are commercially acceptable and competitively priced, which provides professional technicians and DIYers with an affordable alternative for repairs.

Product Features:

Direct-fit OE replacement ensures ease of installation
Designed to meet OE performance
As the leader in commercially acceptable parts, we provide professional technicians with the quality parts they need
As the leader in commercially acceptable parts, we provide professional technicians with the quality parts they need

Upgrade your 2021 Ford E-450 Super Duty with Top-Quality Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2021 Ford E-450 Super Duty, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Ford or enhancing its overall performance, Ignition and Tune-Up Products are key to keeping your E-450 Super Duty functioning at its best. At Advance Auto Parts, we offer a wide selection of 20 Ignition and Tune-Up Products for the 2021 Ford E-450 Super Duty, designed to meet your needs without breaking the bank. From Ignition Coils and Boot replacements to Ignition Switches upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Ignition and Tune-Up Products for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Ignition and Tune-Up Products for your 2021 Ford E-450 Super Duty at great prices. Our Ignition and Tune-Up Products inventory for this model ranges from just $6.49 to $258.18, with an average price of $48.66. Our 20 Ignition and Tune-Up Products in stock come from 7 trusted brands, so you’re sure to find the right part for your 2021 Ford E-450 Super Duty without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2021 Ford E-450 Super Duty, we stock popular OEM and aftermarket Ignition and Tune-Up Products from top names like Autolite, NGK, E3, and more. Autolite Ignition and Tune-Up Products start at just $6.49 and boast an impressive 5 stars average rating from customers. NGK and E3 also bring quality to the table, with Ignition and Tune-Up Products available starting at $8.49, and at an average 5 stars rating. With 221 customer reviews and counting, our 2021 Ford E-450 Super Duty Ignition and Tune-Up Products have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Ignition and Tune-Up Product upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 Ford E-450 Super Duty is always ready to roll. We’re committed to providing you with everything you need to keep your E-450 Super Duty in top shape, all in one place. Start shopping confidently below for your 2021 Ford E-450 Super Duty!

Best-Selling Ignition Coils and Boots for 2021 Ford E-450 Super Duties

Enhance the driving experience in your Ford with 2 quality Ignition Coils and Boot components, starting at $201.99.

show more show less

from

$258.18

DIRECT IGNITION COIL

from

$201.99

Ignition Coil

Top Picks for 2021 Ford E-450 Super Duty Ignition Boots

Upgrade Ford E-450 Super Duties with top-quality Ignition Boots parts, including 1 OEM and aftermarket selections for your 2021 model.

show more show less

from

$21.79

Backed by Motorcraft’s Service Parts Warranty
Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
Motorcraft ignition components help prevent false check engine lights.

In-Demand Spark Plugs for 2021 Ford E-450 Super Duties

Select from 12 premium Spark Plugs parts for your 2021 Ford E-450 Super Duty, with prices ranging from $6.49 to $14.79.

show more show less

from

$9.99

Our best spark plug! Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.

Product Features:

0.6 mm finewire design improves ignitability
Patented V-trimmed platinum sidewire technology resists wear
OE equivalent design is engineered for every engine
Designed for better overall durability with virtually no gap erosion
Double Iridium-Enhanced Alloy Technology Center Electrode: Offers improved durability and wear resistance for a longer-lasting spark plug.
Engineered in the USA: Designed with over 100 years of Autolite’s engineering experience for superior quality and performance.
Proven Track Record: Part of a legacy with over 11 billion spark plugs sold, ensuring trusted performance and reliability.

from

$6.49

Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, Autolite Double Platinum spark plugs feature platinum-to-platinum firing which virtually eliminates gap erosion, reduces misfires and increases durability of the plug. Consider upgrading to Autolite Iridium XP spark plugs for increased performance.

Product Features:

Works to optimize engine performance for a longer life and improved fuel economy
OE design
Full-platinum tips; platinum on both the center and side electrodes to promote reduced gap wear
Platinum ball welding process provides a consistent point of contact for enhanced adhesion

from

$14.79

NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug; Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:

HIGH IGNITABILITY PROJECTED SQUARE PLATINUM ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with a unique cut-back PSPE ground electrode
RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
PSPE DESIGN: Projected square platinum electrode shape of the ground electrode provides the best ignitability and service life for high heat engines
SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
RECOMMENDED USAGE: Modern vehicles using OE PSPE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
Enhanced Fuel Burn: Provides a more complete fuel burn, resulting in quicker throttle response, smoother idle, and better cold starts.
Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.

from

$8.49

The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.74 is a 14mm, 1.000 reach plug with a taper seat. It fits a wide variety of late model applications, especially Ford applications. The automotive plugs have three legs securing the Diamond FIRE electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond FIRE side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:

E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
The Spark Plugs are pre-gapped at the factory and cannot be adjusted.
Enhanced Heat Transfer: Three legs securing the Diamond FIRE electrode to the shell ensure excellent heat transfer and create more turbulence in the cylinder.
Wide Compatibility: The E3.74 spark plug is a 14mm, 1.000 reach plug with a taper seat, fitting a wide variety of late model applications, especially Ford vehicles.
Eco-Friendly Performance: Proven to reduce fuel consumption and improve hydrocarbon emissions, contributing to a cleaner environment.
Long-Term Efficiency: The Diamond FIRE side wire is designed for long-term use, maintaining increased power and reduced fuel consumption over time.

from

$10.99

Autolite Iridium Ultra Laser Finewire Spark Plugs are one of our brand’s most technologically advanced products. These spark plugs provide superior durability, more focused ignition with better overall ignitability for optimum performance. Autolite Spark Plugs are the best alternative to OE spark plugs, offering OE fit form and function supporting all foreign and domestic makes and models at a value price. Autolite provides the automotive aftermarket and original equipment manufacturers with the highest quality ignition products and is the leading supplier of spark plugs in the world.

Product Features:

Autolite Iridium Ultra is an engineered OE replacement iridium spark plug.
A laser-welded 0.5mm pure iridium finewire center electrode provides optimal fuel efficiency, acceleration and focused ignitability.
Nickel-plated shell to resist corrosion.
High-alumina ceramic insulator for increased strength.
Laser welded 0.5mm Iridium finewire center electrode.
Proprietary platinum sidewire technology.
Superior Durability: Autolite Iridium Ultra Laser Finewire Spark Plugs are designed to last longer, providing extended service life compared to standard spark plugs.
OE Fit and Function: Autolite Spark Plugs are the best alternative to original equipment (OE) spark plugs, offering perfect fit, form, and function for all foreign and domestic makes and models.
High-Quality Construction: As a leading supplier of spark plugs globally, Autolite ensures the highest quality ignition products for both the automotive aftermarket and original equipment manufacturers.
Value Pricing: Despite their advanced technology and superior performance, Autolite Iridium Ultra Laser Finewire Spark Plugs are available at a value price, making them an economical choice for vehicle maintenance.

from

$13.99

NGK Laser Platinum spark plugs provide high ignitability and longer service life compared to conventional nickel spark plugs. Laser Platinum plugs are tested to the highest standards to ensure quality and durability. Engineered specifically for OE applications. Laser platinum plugs provide stable idling, superior anti-fouling, improved fuel efficiency and lower emissions. High-grade pure alumina ceramic and 98% pure copper core prevents spark plug from overheating and provides reliable starts. Most Laser Platinum spark plugs feature a platinum pad on the ground electrode for even wear in distributorless ignition systems.

Product Features:

ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction fine wire platinum alloy center electrode provides consistent performance
PLATINUM ALLOY CENTER ELECTRODE: Longer wearing and higher temperature resistance compared to traditional nickel spark plugs
PLATINUM TIP GROUND ELECTRODE: Unless OE specified, platinum protection at the ground electrode provides excellent ignitability and service life
SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
RECOMMENDED USAGE: Best for vehicles with OE fine wire platinum alloy plugs

from

$14.49

Ir SparkPlug

from

$13.24

Tapered cut, U-Groove ground electrode
0.4mm iridium center electrode
360-degree laser welding assembly process
Required ignition voltage reduced
Unsurpassed center electrode durability
Available for many performance and power sports applications, including Corvette, Viper, and Harley-Davidson The Iridium Power plug delivers greater spark energy while demanding significantly less secondary required voltage from the ignition system.

from

$9.33

Motorcraft Original Equipment Platinum Iridium spark plugs are designed, engineered and recommended by Ford Motor Company.

Product Features:

Same part installed when the engine rolled off the assembly line
100,000-mile service interval
Platinum ball on the center electrode minimizes gap erosion for longer life
Proprietary platinum ball welding process provides a consistent point of contact for better adhesion
Fewer misfires and reduced gap erosion
Optimizes engine performance to provide improved fuel economy

from

$9.10

Spark Plug

from

$8.99

0.6 mm finewire design improves ignitability
Patented V-trimmed platinum sidewire technology resists wear
OE equivalent design is engineered for every engine
Designed for better overall durability with virtually no gap erosion

from

$7.99

Engineered for superior ignition performance, the Motorcraft High-Performance Spark Plug is designed to optimize fuel efficiency and ensure reliable starts. Crafted with precision, this spark plug offers exceptional durability and consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance. Upgrade to Motorcraft and experience the difference in your engine’s responsiveness and fuel economy.

Product Features:

Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.
Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.

Most Sold 2021 Ford E-450 Super Duty Ignition Sensors

Explore our best-selling Ford parts for the 2021 E-450 Super Duty among 1 OEM and aftermarket options starting from $23.99.

show more show less

from

$23.99

Top-Rated Ignition and Tune-Up Products Brands For Your 2021 Ford E-450 Super Duty

Shop for the best-rated brands offering Ignition and Tune-Up Products and other products for your 2021 Ford E-450 Super Duties. Below you’ll find some of our best rated Ignition and Tune-Up Products from Autolite, NGK, and E3, and more. Ignition and Tune-Up Products from these brands that fit a 2021 E-450 Super Duty start at just $6.49 and are rated as high as 5 stars. OEM and aftermarket Ignition and Tune-Up Products don’t get more top quality, durable, and affordable than from the brands below.

Popular Autolite 2021 Ford E-450 Super Duty Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2021 Ford E-450 Super Duty, using quality Ignition and Tune-Up Products is essential to ensure durability and a perfect fit. Autolite ticks all of those boxes. We offer a wide selection of Autolite Ignition and Tune-Up Products, specifically designed for the 2021 Ford E-450 Super Duty. With over 5 Autolite brand Ignition and Tune-Up Products in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $6.49, with an average price of just $10.19. Plus, with over 43 customer reviews and an average rating of 5 stars, you can trust that our Autolite Ignition and Tune-Up Products will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

from
$10.99

This product is not rated

Iridium Ultra Finewire Spark Plug: Optimal Performance, Durability, Ignitability

“”

from
$14.49

This product is not rated

Ir SparkPlug

“”

from
$8.99

This product is not rated

Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition

“”

Popular NGK 2021 Ford E-450 Super Duty Ignition and Tune-Up Products

NGK auto parts is one of the highest quality Ignition and Tune-Up Product brands in the market. Any 2021 Ford E-450 Super Duty owner should feel confident when installing genuine NGK parts in their vehicle. To ensure the best fit and performance for your 2021 E-450 Super Duty, Advance Auto Parts carries a full inventory of 2 NGK Ignition and Tune-Up Products. Plus you will be keeping your Ford in peak condition while saving money because prices on these NGK Ignition and Tune-Up Products range from $13.99 to $14.79, plus, with more than 1 customer reviews and an impressive 5 stars average rating, you can be confident the Fram Ignition and Tune-Up Products below will deliver on both quality and value.

from
$14.79

(1)

Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX

“I got these for my 2019 Mustang Ecoboost and these were way better spark plugs then anything i have tried definitely a performance oriented, spark plu”

from
$13.99

This product is not rated

OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13

“”

FAQs for 2021 Ford E-450 Super Duty Ignition and Tune-Up Products

Which Ignition and Tune-Up Products are best-sellers for 2021 Ford E-450 Super Duties?

Out of 20 Ignition and Tune-Up Products that fit 2021 Ford E-450 Super Duties, the following parts are the top sellers:

Iridium Ultra Finewire Spark Plug: Optimal Performance, Durability, Ignitability (12008336) – $10.99
Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX (12069657) – $14.79
Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (11333712) – $21.79

What’s the price range for 2021 Ford E-450 Super Duty Ignition and Tune-Up Products?

Ignition and Tune-Up Product prices for the 2021 Ford E-450 Super Duty start at $6.49 and go up to $258.18 for the most premium parts.

What’s the average price of a Ignition and Tune-Up Product for a 2021 Ford E-450 Super Duty?

The average price for Ignition and Tune-Up Products for the 2021 Ford E-450 Super Duty is $48.66. Keep in mind the variety of part types within our Ignition and Tune-Up Product category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Ignition and Tune-Up Products for other Ford E-450 Super Duty model years?

Yes, we currently carry Ignition and Tune-Up Products for 20 model years of Ford E-450 Super Duties between 2003 and 2025. Ignition and Tune-Up Products are bought most frequently for the following model years: 2023, 2022, 2024, 2019, 2018, 2017, 2016, 2015, and 2014.

What are the cheapest Ignition and Tune-Up Products for my 2021 Ford E-450 Super Duty?

The cheapest 2021 Ford E-450 Super Duty Ignition and Tune-Up Products we carry in stock are:

Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life (11668265) – $6.49
High-Performance Spark Plug: Enhances Fuel Efficiency (50011448) – $7.99
DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (11333297) – $8.49
Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition (50031864) – $8.99
Spark Plug (12614208) – $9.10

What are the top-rated Ignition and Tune-Up Products that fit the 2021 Ford E-450 Super Duty?

Out of 221 reviews by customers, our 2021 Ford E-450 Super Duty Ignition and Tune-Up Products have an average customer rating of . These are some of the highest-rated Ignition and Tune-Up Product types for the 2021 Ford E-450 Super Duty and their top-rated products:

Spark Plugs
- Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life (11668265) – $6.49
- Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition (10500916) – $9.99
- Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX (12069657) – $14.79

What types of Ignition and Tune-Up Products do you sell for my 2021 Ford E-450 Super Duty?

As of 2/5/25, these are some of the most in-demand types of Ignition and Tune-Up Products for a 2021 Ford E-450 Super Duty:

Can I get help with 2021 Ford E-450 Super Duty Ignition and Tune-Up Product orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Ignition and Tune-Up Products and more.

What is your return policy for Ford E-450 Super Duty Ignition and Tune-Up Products?

Advance Auto Parts keeps returns simple. For new Ford E-450 Super Duty Ignition and Tune-Up Products and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2021 Ford E-450 Super Duty Ignition and Tune-Up Products

NGK – G-Power Spark Plug: Single Platinum Tip Design, LTR6GP (Part No.90198)

ACDelco – Iridium Spark Plug: Original Equipment Replacement (Part No.41-988)

E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.53)

Motorcraft – High-Durability Spark Plug: Reduces Misfires & Fuel Consumption (Part No.SP-526-X)

DENSO – Iridium Power Spark Plug (Part No.F1000131221ND)

Bosch – Knock Sensor (Part No.0261231316)

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBC3679)

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBA3805)

NTK – Ignition Knock (Detonation) Sensor (Part No.ID0141)

Forecast – Forecast Knock Sensor (Part No.F6020200559FOR)

Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

Carquest Premium – Coil On Plug Insulator Boot Multi Pack, Spring included (Part No.38-001FMP)

Accel – Pc Cop Boots 97-11 Ford 8-Cyl (Part No.128041)

NGK – Coil on Plug Boot (Part No.59022)

Carquest Premium – Ignition Switch (Part No.CSC1044)

Motorcraft – Ignition Switch (Part No.M5050427804MTR)

Carquest – Ignition Switch (Part No.CS273)

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6958)

Carquest Premium – Ignition Switch (Part No.CSA1262)

Carquest Premium – Ignition Switch (Part No.CSC2484)

Motorcraft – Ignition Switch (Part No.M5050675470MTR)

Carquest Premium – Ignition Coil: Meets or Exceeds OE Specifications, 1 Count (Part No.EBC1044)

Delphi – Ignition Coil (Part No.GN10164)

NGK – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.48688)

Accel – High-Performance Ignition Coils for Ford 2-Valve Engines (Part No.140032)

Carquest Premium – Ignition Coil Set: Meets or Exceeds OE Specifications, 8 Count (Part No.EBC1342-8)

Carquest Premium – Ignition Coil Set: Meets or Exceeds OE Specifications, 4 Count (Part No.EBC1045-4)

Driveworks – Ignition Coil (Part No.26326)

Worldpac – DIRECT IGNITION COIL (Part No.F30053386988MTR)

Carquest Premium – Ignition Coil (Part No.EBA2001)

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6958)

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6573)

Motorcraft – Ignition Switch (Part No.M5050485141MTR)

Carquest Premium – Ignition Switch (Part No.CSC3797)

Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

Autolite Iridium – Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition (Part No.XP5363)

Autolite – Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life (Part No.APP5363)

NGK – Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX (Part No.95605)

E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.74)

Autolite Iridium – Iridium Ultra Finewire Spark Plug: Optimal Performance, Durability, Ignitability (Part No.AI5363)

NGK – OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13 (Part No.94862)

Autolite Iridium – Ir SparkPlug (Part No.AI5862)

DENSO – Iridium Power Spark Plug (Part No.F1000312474ND)

Motorcraft – Original Equipment Platinum Iridium Spark Plug (Part No.F1000411669MTR)

Motorcraft – Spark Plug (Part No.F10003269731MTR)

Autolite Iridium – Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition (Part No.XP5862)

Motorcraft – High-Performance Spark Plug: Enhances Fuel Efficiency (Part No.SP-589)

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBA3805)