2021 Ford E-450 Super Duty Ignition and Tune-Up Products

Essential Ignition and Tune-Up Products for 2021 Ford E-450 Super Duties

Carquest Premium – Ignition Coil (Part No.EBA2001)

Ignition Coil

from

$201.99
Carquest Premium ignition coils meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coils are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coils with an industry-leading warranty. Carquest Premium ignition coils are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Built by IATF 16949 certified manufacturers for consistent durability
  • Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
  • Segmented secondary bobbins to distribute high voltage and prevent shorting
  • 100% end-of-line tested to ensure proper performance
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Carquest Premium – Ignition Coil (Part No.EBC1342)

Ignition Coil

from

$73.99
Carquest Premium engine management products provide the right ignition coils for a wide range of domestic and import applications. They deliver the highest performance and durability under demanding conditions. Designed to meet OE quality and performance

Product Features:
  • Coils are designed and engineered to be an OE quality replacement for fit and performance
  • High-strength dielectric epoxy and 100% copper windings used to deliver high-temperature performance and vibration resistance
  • High-efficiency laminations produce a high-energy spark and reliable performance
  • Factories use ISO 9001 and IATF 16949 standards to deliver products designed to meet or exceed OE voltage output specifications
  • Top-quality components and materials used to deliver maximum performance and long service life under tough operating conditions
  • Long service life
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Carquest Premium – Ignition Coil (Part No.EBE1963)

Ignition Coil

from

$100.99
Carquest Premium ignition coils meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coils are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coils with an industry-leading warranty. Carquest Premium ignition coils are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Built by IATF 16949 certified manufacturers for consistent durability
  • Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
  • Segmented secondary bobbins to distribute high voltage and prevent shorting
  • 100% end-of-line tested to ensure proper performance
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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MSD Ignition – Blue Ford COP Coil 2 (Part No.82425)

Blue Ford COP Coil 2

from

$57.99
Blue Ford COP Coil 2

Carquest Premium – Spark Plug Boot Set: 8 Boots, Meets or Exceeds OE Specifications (Part No.38-001FMP)

Spark Plug Boot Set: 8 Boots, Meets or Exceeds OE Specifications

from

$38.99
Carquest Premium spark plug boot sets are engineered to restore ignition boot reliability and performance. They are designed to meet or exceed original equipment (O.E.) specifications for fit, form and function. Our spark plug boots offer excellent heat resistance as well as maximum protection against spark loss. Carquest Premium spark plug boot sets are built with a durable silicone compound for resistance to high heat and abrasion, resulting in a longer-lasting ignition repair. Carquest Premium spark plug boot sets include all boots needed for each vehicle application for a complete tune-up repair.

Product Features:


    Product Features:
    • Complete set of boots for a complete tune-up and better value
    • OE design provides an exact fit for your application
    • Provides excellent heat resistance as well as maximum protection against spark loss
    • Durable silicone compound for resistance to high heat or abrasion
    • Spring included with the coil boot
    • Design for direct compatibility
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Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1

from

$21.79
Motorcraft Ignition Boots are engineered to provide original equipment performance and reliability. All Motorcraft parts undergo rigorous lab and real-world tests in order to meet strict Ford engineering standards. Terminal ends are designed to help ensure they do not separate from the cable under normal service conditions. High dialectic insulation helps maintain and control voltage delivery while reducing radio frequency interference. The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles

Product Features:
  • Backed by Motorcraft’s Service Parts Warranty
  • Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
  • Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
  • Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
  • Motorcraft ignition components help prevent false check engine lights.
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Accel – Pc Cop Boots 97-11 Ford 8-Cyl (Part No.128041)

Pc Cop Boots 97-11 Ford 8-Cyl

from

$56.99
Pc Cop Boots 97-11 Ford 8-Cyl

Motorcraft – High-Durability Spark Plug: Reduces Misfires & Fuel Consumption (Part No.SP-526-X)

High-Durability Spark Plug: Reduces Misfires & Fuel Consumption

from

$9.99
Motorcraft Spark Plugs are original equipment on Ford Motor Company vehicles, engineered to meet strict Ford engineering standards for performance and reliability. These spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption, and optimize emissions. They are resistant to oxidation and arc erosion, feature a multi-rib insulator to protect against misfire, and offer service intervals of up to 100,000 miles. Backed by Motorcraft’s Service Parts Warranty, these spark plugs are an exact fit for Ford, Lincoln, and Mercury vehicles and are designed with high-quality materials to provide reliable performance for almost any application. Motorcraft ignition components also help prevent false check engine lights, ensuring your vehicle runs smoothly.

Product Features:
  • Motorcraft spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption and optimize emissions.
  • Backed by Motorcraft’s Service Parts Warranty
  • Exact fit for Ford, Lincoln and Mercury vehicles
  • Resistant to oxidation and arc erosion.
  • Multi-rib insulator protects against misfire.
  • Service intervals of up to 100,000 miles.
  • Motorcraft Spark Plugs are designed with high quality materials to provide reliable performance for almost any application.
  • Motorcraft Spark Plugs are what was in the vehicle when it was manufactured
  • Motorcraft ignition components help prevent false check engine lights.
  • Engineered for Ford Vehicles: Motorcraft High-Durability Spark Plugs are original equipment on Ford, Lincoln, and Mercury vehicles, ensuring a perfect fit and optimal performance.
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DENSO – Double Platinum Spark Plug: OE Performance, lasts 60K+ Miles, PT16EPR-L13 (Part No.5070)

Double Platinum Spark Plug: OE Performance, lasts 60K+ Miles, PT16EPR-L13

from

$11.99
Double Platinum Spark Plug PT16EPR-L13 is engineered to meet the highest OE standards for performance, durability, and emissions. Featuring OE-grade platinum on both center and ground electrodes, it ensures superior thermal conductivity and sustained spark performance for over 60,000 miles. The premium shell construction with machine-rolled threads enhances durability and provides a secure fit, while the tapered seat type ensures optimal compatibility with your engine. Designed to reduce secondary required voltage and increase ignition efficiency, this spark plug delivers reliable performance and helps minimize shop comebacks, ensuring customer satisfaction. With its double platinum design, it offers exceptional longevity and consistent ignition, making it a valuable addition to your vehicle’s ignition system.

Product Features:
  • OE grade platinum on both center and ground electrodes
  • Premium shell construction with machine-rolled threads
  • Superior thermal conductivity
  • Sustained spark performance over 60,000 miles
  • Reduced secondary required voltage, increased ignition efficiency
  • Satisfied customers, reduced shop comebacks
  • Double Platinum
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NGK – Ruthenium HX Spark Plug (TR5AHX): High Ignitability & Durability (Part No.94567)

Ruthenium HX Spark Plug (TR5AHX): High Ignitability & Durability

from

$15.99
NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug, Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:
  • HIGH IGNITABILITY DOUBLE FINE ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with opposed fine wire platinum ground electrode
  • RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
  • PLATINUM PIN TYPE GROUND ELECTRODE: Provides more complete fuel burn, quicker throttle response, smoother idle and better cold starts
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modern vehicles using OE DFE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
  • Specialized OEM Tip Designs: Features DFE and PSPE tip designs for enhanced ignitability and efficiency.
  • Industry-Leading Durability: Ruthenium center electrode ensures long-lasting performance and reliability.
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Champion – Platinum Power Spark Plug (RS10PYC): Powerful Performance & Durability (Part No.3408)

Platinum Power Spark Plug (RS10PYC): Powerful Performance & Durability

from

$4.49
Champion Platinum Power spark plugs are engineered to deliver exceptional performance and durability, making them an ideal choice for maintaining peak engine efficiency. Featuring a platinum center electrode, these spark plugs ensure long-lasting reliability and consistent performance. The fine-wire center electrode enhances ignitability, while the V-trimmed ground electrode sharpens spark focus for optimal combustion. Constructed with the exclusive Heat-Active alloy, these plugs quickly reach and maintain the ideal operating temperature, ensuring smooth engine operation under various conditions. The platinum-tipped center wire resists wear and helps maintain the proper gap specification throughout the plug’s lifespan, reducing the need for frequent replacements. Designed as a standard replacement with a tapered seat type, these spark plugs are compatible with a wide range of vehicles. With a nickel ground electrode tip and integrated resistor, they provide dependable performance and value, making them a smart investment for any vehicle owner seeking reliable ignition components.

Product Features:
  • Platinum Power- Premium Spark Plug. Powerful Performance.
  • Platinum center electrode for long life
  • Fine-wire center electrode for greater ignitability
  • V-trimmed ground electrode promotes sharper spark focus
  • Heat-Active alloy allows electrodes to reach optimal temperature
  • Platinum tipped center wire resists wear and helps to maintain proper gap spec over life of the plug
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DENSO – Iridium TT Spark Plug: Ultimate Endurance and Power, 0.4mm Iridium Tip, ITV20TT (Part No.4719)

Iridium TT Spark Plug: Ultimate Endurance and Power, 0.4mm Iridium Tip, ITV20TT

from

$13.99
The Iridium TT Spark Plug combines the durability of an OE-style plug with the power and torque of high-performance engineering, making it a top choice for demanding drivers. Featuring a 0.4mm Iridium center electrode – the world’s smallest diameter – it maximizes firing potential for superior ignition. The 0.7mm needle tip ground electrode promotes higher spark energy while reducing heat quenching, ensuring consistent performance. Built with DENSO’s patented Iridium-Rhodium alloy formula, it boasts the highest concentration of Iridium among competitors, delivering unmatched durability. The 360-degree laser welding process ensures a robust bond and structural integrity, even under extreme conditions. With the ability to withstand temperatures exceeding 4000 Deg F, this spark plug is engineered for ultimate endurance. Its tapered seat design further enhances compatibility and fitment. Whether you’re seeking enhanced power or long-lasting reliability, this Iridium TT plug delivers exceptional value and performance.

Product Features:
  • 0.4mm Iridium Center Electrode: World’s Smallest Diameter that maximizes firing potential
  • 0.7mm Needle Tip Ground Electrode: Promotes higher spark energy and less heat quenching
  • DENSO Patented Optimized Iridium-Rhodium Alloy Formula: Highest concentration of Iridium vs. competitors for greater durability
  • DENSO Patented 360 degree laser welding process: Ensuring exceptional quality bond and structural strength with the Iridium Center Electrode
  • Durability of an OE style plug combined with Power and Torque of high performance.
  • Withstands temperatures greater than 4000 degree Fahrenheit
  • Iridium TT
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Motorcraft – Single Lead Spark Plug Wire (Part No.WR-6170)

Single Lead Spark Plug Wire

from

$39.99
Motorcraft Single Lead Spark Plug Wires must endure a series of punishing tests including a series of demanding test-to-failure endurance and materials durability tests to ensure their long-lasting quality and operation.

Product Features:
  • The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.
  • Motorcraft ignition system components create and control the electrical functions of engine operation in Ford-built vehicles.
  • The ignition includes the Ignition Coil and modules that generate up to 46,000 volts for spark plug firing as well as the crankshaft position monitor and Power Train Control module or PCM.
  • Motorcraft Ignition components are manufactured to exacting Ford OE specifications and quality standards.
  • As with all Motorcraft aftermarket parts, any engineering innovations or product improvements developed since the vehicle’s manufacture are added to these Ignition components, ensuring the most current technology.
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Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBC3679)

Ignition Knock (Detonation) Sensor

from

$35.99
Carquest Knock Sensors respond to a wide range of engine knock frequencies providing accurate engine condition to the ECM for optimal ignition timing. Highest quality piezoceramic element manufactured to tight tolerances for increased durability. All Carquest Knock Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • Precision piezoceramic element ensures accurate response to a wide range of engine vibrations
  • Manufactured using the highest quality OEM materials to ensure optimal performance and rugged durability
  • Designed to meet or exceed all OEM specifications in fit, form & function
  • Extensive product testing includes salt spray, high/low temperature impact, thermal cycling, vibration, drop among other tests, to ensure all sensors meet or exceed OEM specifications.
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NTK – Ignition Knock (Detonation) Sensor (Part No.ID0141)

Ignition Knock (Detonation) Sensor

from

$66.99
The Ignition Knock (Detonation) Sensor monitors vibrations caused by engine knock or detonation to alter the ignition timing and prevent detonation. A piezoelectric crystal generates a varying voltage based upon engine vibration intensity to delay ignition timing to help prevent severe and costly engine damage. Reasons for replacement include check engine light illumination, engine hesitation, poor fuel economy or failed emissions test.

Product Features:
  • ADVANCED TECHNOLOGY: Manufactured to operation performance standards to meet or exceed OE fit, form, and function to ensure proper ignition timing.
  • INSTALLATION AND SUPPORT: Mounting threads, harness length and wire gauge match OE for easy, worry free installation.
  • THE DIFFERENCE: Reinforced components are used to reduce the chance of part failure and prevent corrosion and moisture penetration. Shielded harness prevents electrical interference.
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Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBA3805)

Ignition Knock (Detonation) Sensor

from

$26.99
Carquest Premium knock sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium knock sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. We utilize advanced technology to design sensors that are, in many cases, stronger than OE parts. Carquest Premium knock sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium knock sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • Trivalent iridescent chromate plating prevents corrosion
  • Silicone seals prevent moisture intrusion preventing false codes and sensor failure
  • Wiring harnesses utilize high-temperature insulation when applicable
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Bosch – Knock Sensor (Part No.0261231316)

Knock Sensor

from

$28.99
Bosch OE quality knock sensors for optimum engine protection and fuel consumption reduction up to 9%.

Product Features:
  • Bosch OE quality knock sensors for optimum engine protection
  • Bosch OE quality knock sensors increase torque up to 5%
  • Bosch OE quality knock sensors enable the use of multiple quality fuels with various anti-knock properties
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Carquest Premium – Ignition Switch (Part No.CSC2484)

Ignition Switch

from

$47.99
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The Ignition Switch allows for reliable control of the vehicle’s electrical systems and engine start-up, enhancing convenience and ensuring consistent performance during operation. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
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Carquest Premium – Ignition Switch (Part No.CSA1262)

Ignition Switch

from

$30.49
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The Ignition Switch allows for reliable control of the vehicle’s electrical systems and engine start-up, enhancing convenience and ensuring consistent performance during operation. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
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Carquest – Ignition Switch (Part No.CS942)

Ignition Switch

from

$40.99
High-quality products that meet OE appearance and performance to provide professional technicians and DIYers with a cost-effective solution.

Product Features:
  • Designed to OE standards for ease of installation
  • Copper alloy conductors ensure superior electrical conductivity with low resistive losses
  • Our parts are 100% tested to verify both mechanical and electrical switching performance
  • Robust design and high grade materials meet the stringent demands of today’s service professional
  • BWD is a global manufacturer of original equipment ignition products, complete quality control is maintained through the manufacturing process from componentry to finished product
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Carquest Premium – Ignition Switch (Part No.CSC3797)

Ignition Switch

from

$62.99
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The Ignition Switch allows for reliable control of the vehicle’s electrical systems and engine start-up, enhancing convenience and ensuring consistent performance during operation. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
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Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6573)

Original Equipment (O.E.) Switch Assembly - Ignition

from

$99.99
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:
  • Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
  • All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.
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Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6958)

Original Equipment (O.E.) Switch Assembly - Ignition

from

$83.99
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:
  • Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
  • All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.
See More

Carquest Premium – Ignition Switch (Part No.CSC1044)

Ignition Switch

from

$70.99
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The Ignition Switch allows for reliable control of the vehicle’s electrical systems and engine start-up, enhancing convenience and ensuring consistent performance during operation. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
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Upgrade your 2021 Ford E-450 Super Duty with Top-Quality Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2021 Ford E-450 Super Duty, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Ford or enhancing its overall performance, Ignition and Tune-Up Products are key to keeping your E-450 Super Duty functioning at its best. At Advance Auto Parts, we offer a wide selection of 16 Ignition and Tune-Up Products for the 2021 Ford E-450 Super Duty, designed to meet your needs without breaking the bank. From Ignition Coils and Boot replacements to Ignition Switches upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Ignition and Tune-Up Products for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Ignition and Tune-Up Products for your 2021 Ford E-450 Super Duty at great prices. Our Ignition and Tune-Up Products inventory for this model ranges from just $6.99 to $201.99, with an average price of $39.76. Our 16 Ignition and Tune-Up Products in stock come from 5 trusted brands, so you’re sure to find the right part for your 2021 Ford E-450 Super Duty without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2021 Ford E-450 Super Duty, we stock popular OEM and aftermarket Ignition and Tune-Up Products from top names like NGK, Autolite, E3, and more. NGK Ignition and Tune-Up Products start at just $14.99 and boast an impressive 4.8 stars average rating from customers. Autolite and E3 also bring quality to the table, with Ignition and Tune-Up Products available starting at $6.99, and at an average 4.6 stars rating. With 221 customer reviews and counting, our 2021 Ford E-450 Super Duty Ignition and Tune-Up Products have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Ignition and Tune-Up Product upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 Ford E-450 Super Duty is always ready to roll. We’re committed to providing you with everything you need to keep your E-450 Super Duty in top shape, all in one place. Start shopping confidently below for your 2021 Ford E-450 Super Duty!

Best-Selling Ignition Coils and Boots for 2021 Ford E-450 Super Duties

Enhance the driving experience in your Ford with 1 quality Ignition Coils and Boot components, starting at $201.99.

Carquest Premium – Ignition Coil (Part No.EBA2001)

Ignition Coil

from

$201.99
Carquest Premium ignition coils meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coils are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coils with an industry-leading warranty. Carquest Premium ignition coils are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Built by IATF 16949 certified manufacturers for consistent durability
  • Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
  • Segmented secondary bobbins to distribute high voltage and prevent shorting
  • 100% end-of-line tested to ensure proper performance
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
See More

Most Popular 2021 Ford E-450 Super Duty Ignition Switches

Customize your Ford with 3 Ignition Switches products like Ignition Starter Switches, all priced under $99.99.

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6958)

Original Equipment (O.E.) Switch Assembly - Ignition

from

$83.99
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:
  • Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
  • All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.
See More

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6573)

Original Equipment (O.E.) Switch Assembly - Ignition

from

$99.99
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:
  • Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
  • All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.
See More

Carquest Premium – Ignition Switch (Part No.CSC3797)

Ignition Switch

from

$62.99
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The Ignition Switch allows for reliable control of the vehicle’s electrical systems and engine start-up, enhancing convenience and ensuring consistent performance during operation. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
See More

Top Picks for 2021 Ford E-450 Super Duty Ignition Boots

Upgrade Ford E-450 Super Duties with top-quality Ignition Boots parts, including 1 OEM and aftermarket selections for your 2021 model.

Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1

from

$21.79
Motorcraft Ignition Boots are engineered to provide original equipment performance and reliability. All Motorcraft parts undergo rigorous lab and real-world tests in order to meet strict Ford engineering standards. Terminal ends are designed to help ensure they do not separate from the cable under normal service conditions. High dialectic insulation helps maintain and control voltage delivery while reducing radio frequency interference. The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles

Product Features:
  • Backed by Motorcraft’s Service Parts Warranty
  • Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
  • Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
  • Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
  • Motorcraft ignition components help prevent false check engine lights.
See More

In-Demand Spark Plugs for 2021 Ford E-450 Super Duties

Select from 10 premium Spark Plugs parts for your 2021 Ford E-450 Super Duty, with prices ranging from $6.99 to $39.99.

Autolite Iridium – Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition (Part No.XP5363)

Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition

from

$10.99
Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.

Product Features:
  • 0.6 mm finewire design improves ignitability
  • Patented V-trimmed platinum sidewire technology resists wear
  • OE equivalent design is engineered for every engine
  • Designed for better overall durability with virtually no gap erosion
  • Double Iridium-Enhanced Alloy Technology Center Electrode: Offers improved durability and wear resistance for a longer-lasting spark plug.
  • Engineered in the USA: Designed with over 100 years of Autolite’s engineering experience for superior quality and performance.
  • Proven Track Record: Part of a legacy with over 11 billion spark plugs sold, ensuring trusted performance and reliability.
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Autolite – Double Platinum Spark Plug: Enhanced Durability & Performance (Part No.APP5363)

Double Platinum Spark Plug: Enhanced Durability & Performance

from

$6.99
The Double Platinum Spark Plug is engineered for exceptional durability and performance, making it a top choice for distributor-less ignition system (DIS) engines. Featuring a platinum-to-platinum design, it minimizes gap erosion and reduces misfires, ensuring a longer service life compared to copper and standard platinum plugs. Its yttrium-enhanced ground electrode delivers superior heat transfer, allowing it to withstand high temperatures and pressures for extended durability. The high alumina ceramic insulator optimizes thermal conductivity and dielectric strength, while the multi-rib insulator prevents flash-over for reliable operation. With a mid-projection center electrode and tapered seat type, this performance-grade spark plug is designed to deliver consistent ignition and efficiency. Both the center and ground electrode tips are crafted from platinum, ensuring robust functionality and reliability. Ideal for those seeking enhanced engine performance and longevity, this spark plug is built to meet the demands of modern engines.

Product Features:
  • Engineered with a platinum-to-platinum design that prevents gap erosion, extending the life of the spark plug.
  • The yttrium-Enhanced Ground Electrode delivers superior heat transfer that delivers more durability under high temps and pressure for greater life.
  • Its high alumina ceramic insulator provides optimum thermal conductivity and dielectric strength.
  • The multi-rib insulator prevents flash-over.
  • Designed with a mid-projection center electrode and tapered seat type to ensure consistent ignition and improved engine efficiency.
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NGK – Ruthenium HX Spark Plug (LTR7BHX): High Ignitability & Durability (Part No.95605)

Ruthenium HX Spark Plug (LTR7BHX): High Ignitability & Durability

from

$14.99
NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug, Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:
  • HIGH IGNITABILITY PROJECTED SQUARE PLATINUM ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with a unique cut-back PSPE ground electrode
  • RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
  • PSPE DESIGN: Projected square platinum electrode shape of the ground electrode provides the best ignitability and service life for high heat engines
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modern vehicles using OE PSPE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
  • Enhanced Fuel Burn: Provides a more complete fuel burn, resulting in quicker throttle response, smoother idle, and better cold starts.
  • Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.
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E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.74)

DiamondFIRE Automotive Spark Plug: More Power, Saves Gas

from

$8.49
The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.74 is a 14mm, 1.000 reach plug with a taper seat. It fits a wide variety of late model applications, especially Ford applications. The automotive plugs have three legs securing the Diamond FIRE electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond FIRE side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:
  • E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
  • Smoother Acceleration & Idle – The faster flame initiated by the spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
  • Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
  • Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
  • E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
  • The Spark Plugs are pre-gapped at the factory and cannot be adjusted.
  • Enhanced Heat Transfer: Three legs securing the Diamond FIRE electrode to the shell ensure excellent heat transfer and create more turbulence in the cylinder.
  • Wide Compatibility: The E3.74 spark plug is a 14mm, 1.000 reach plug with a taper seat, fitting a wide variety of late model applications, especially Ford vehicles.
  • Eco-Friendly Performance: Proven to reduce fuel consumption and improve hydrocarbon emissions, contributing to a cleaner environment.
  • Long-Term Efficiency: The Diamond FIRE side wire is designed for long-term use, maintaining increased power and reduced fuel consumption over time.
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Autolite Iridium – Iridium Ultra Fine Wire Spark Plug: Laser Welded for Optimum Performance (Part No.AI5363)

Iridium Ultra Fine Wire Spark Plug: Laser Welded for Optimum Performance

from

$10.99
Autolite Iridium Ultra Laser Fine wire Spark Plugs are one of our brand’s most technologically advanced products. These spark plugs provide superior durability, more focused ignition with better overall ignitability for optimum performance. Autolite Spark Plugs are the best alternative to OE spark plugs, offering OE fit form and function supporting all foreign and domestic makes and models at a value price. Autolite provides the automotive aftermarket and original equipment manufacturers with the highest quality ignition products and is the leading supplier of spark plugs in the world.

Product Features:
  • Autolite Iridium Ultra is an engineered OE replacement iridium spark plug.
  • A laser-welded 0.5mm pure iridium finewire center electrode provides optimal fuel efficiency, acceleration and focused ignitability.
  • Nickel-plated shell to resist corrosion.
  • High-alumina ceramic insulator for increased strength.
  • Laser welded 0.5mm Iridium finewire center electrode.
  • Proprietary platinum sidewire technology.
  • Superior Durability: Autolite Iridium Ultra Laser Fine wire Spark Plugs are designed to last longer, providing extended service life compared to standard spark plugs.
  • OE Fit and Function: Autolite Spark Plugs are the best alternative to original equipment (OE) spark plugs, offering perfect fit, form, and function for all foreign and domestic makes and models.
  • High-Quality Construction: As a leading supplier of spark plugs globally, Autolite ensures the highest quality ignition products for both the automotive aftermarket and original equipment manufacturers.
  • Value Pricing: Despite their advanced technology and superior performance, Autolite Iridium Ultra Laser Fine wire Spark Plugs are available at a value price, making them an economical choice for vehicle maintenance.
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NGK – Laser Platinum Spark Plug (LTR7CP13): Fine Wire Tip for High Ignitability (Part No.94862)

Laser Platinum Spark Plug (LTR7CP13): Fine Wire Tip for High Ignitability

from

$18.99
NGK Laser Platinum spark plugs provide high ignitability and longer service life compared to conventional nickel spark plugs. Laser Platinum plugs are tested to the highest standards to ensure quality and durability. Engineered specifically for OE applications. Laser platinum plugs provide stable idling, superior anti-fouling, improved fuel efficiency and lower emissions. High-grade pure alumina ceramic and 98% pure copper core prevents spark plug from overheating and provides reliable starts. Most Laser Platinum spark plugs feature a platinum pad on the ground electrode for even wear in distributorless ignition systems.

Product Features:
  • ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction fine wire platinum alloy center electrode provides consistent performance
  • PLATINUM ALLOY CENTER ELECTRODE: Longer wearing and higher temperature resistance compared to traditional nickel spark plugs
  • PLATINUM TIP GROUND ELECTRODE: Unless OE specified, platinum protection at the ground electrode provides excellent ignitability and service life
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Best for vehicles with OE fine wire platinum alloy plugs
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Motorcraft – Single Lead Spark Plug Wire (Part No.WR-6170)

Single Lead Spark Plug Wire

from

$39.99
Motorcraft Single Lead Spark Plug Wires must endure a series of punishing tests including a series of demanding test-to-failure endurance and materials durability tests to ensure their long-lasting quality and operation.

Product Features:
  • The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.
  • Motorcraft ignition system components create and control the electrical functions of engine operation in Ford-built vehicles.
  • The ignition includes the Ignition Coil and modules that generate up to 46,000 volts for spark plug firing as well as the crankshaft position monitor and Power Train Control module or PCM.
  • Motorcraft Ignition components are manufactured to exacting Ford OE specifications and quality standards.
  • As with all Motorcraft aftermarket parts, any engineering innovations or product improvements developed since the vehicle’s manufacture are added to these Ignition components, ensuring the most current technology.
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Autolite Iridium – Iridium Ultra Fine wire Spark Plug: Optimal Fuel Efficiency & Ignitability (Part No.AI5862)

Iridium Ultra Fine wire Spark Plug: Optimal Fuel Efficiency & Ignitability

from

$10.99
The Autolite Iridium Ultra Fine wire Spark Plug is a premium OE replacement designed to deliver exceptional performance and reliability. Featuring a laser-welded proprietary iridium alloy finewire center electrode, it ensures optimal fuel efficiency, improved acceleration, and precise ignitability. The nickel-plated shell offers superior corrosion resistance, while the high-alumina ceramic insulator enhances strength and durability under extreme conditions. With advanced platinum sidewire technology, this spark plug provides long-lasting performance and consistent ignition. Engineered for excellence, its the perfect choice for drivers seeking enhanced engine efficiency and dependable operation.

Product Features:
  • Autolite Iridium Ultra is an engineered OE replacement iridium spark plug.
  • A laser-welded proprietary iridium alloy finewire center electrode provides optimal fuel efficiency, acceleration and focused ignitability.
  • Nickel-plated shell to resist corrosion.
  • High-alumina ceramic insulator for increased strength.
  • Laser welded Iridium finewire center electrode.
  • Proprietary platinum sidewire technology.
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Autolite Iridium – Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition (Part No.XP5862)

Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition

from

$7.99
Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.

Product Features:
  • 0.6 mm finewire design improves ignitability
  • Patented V-trimmed platinum sidewire technology resists wear
  • OE equivalent design is engineered for every engine
  • Designed for better overall durability with virtually no gap erosion
  • Double Iridium-enhanced alloy technology center electrode ensures superior wear resistance for long-lasting performance.
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Motorcraft – High-Performance Spark Plug: Enhances Fuel Efficiency (Part No.SP-589)

High-Performance Spark Plug: Enhances Fuel Efficiency

from

$7.99
The Motorcraft High-Performance Spark Plug is expertly crafted to deliver superior ignition performance and optimize fuel efficiency, ensuring reliable starts and smoother engine operation. Featuring a standard center electrode design with an iridium tip and a nickel ground electrode tip, this spark plug is built for exceptional durability and long-lasting performance. Its tapered seat type ensures a secure fit, making it a dependable choice for maintaining your vehicle’s peak performance. Designed to enhance engine responsiveness and improve overall fuel economy, this spark plug is an excellent upgrade for drivers seeking consistent and efficient performance. With precision engineering and high-quality materials, the Motorcraft High-Performance Spark Plug offers unmatched value, helping you save on fuel costs while keeping your engine running at its best.

Product Features:
  • Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
  • Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
  • Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
  • Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
  • Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.
  • Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
  • Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
  • Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
  • Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
  • Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.
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Most Sold 2021 Ford E-450 Super Duty Ignition Sensors

Explore our best-selling Ford parts for the 2021 E-450 Super Duty among 1 OEM and aftermarket options starting from $26.99.

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBA3805)

Ignition Knock (Detonation) Sensor

from

$26.99
Carquest Premium knock sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium knock sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. We utilize advanced technology to design sensors that are, in many cases, stronger than OE parts. Carquest Premium knock sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium knock sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • Trivalent iridescent chromate plating prevents corrosion
  • Silicone seals prevent moisture intrusion preventing false codes and sensor failure
  • Wiring harnesses utilize high-temperature insulation when applicable
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Top-Rated Ignition and Tune-Up Products Brands For Your 2021 Ford E-450 Super Duty

Shop for the best-rated brands offering Ignition and Tune-Up Products and other products for your 2021 Ford E-450 Super Duties. Below you’ll find some of our best rated Ignition and Tune-Up Products from NGK, Autolite, and E3, and more. Ignition and Tune-Up Products from these brands that fit a 2021 E-450 Super Duty start at just $6.99 and are rated as high as 4.8 stars. OEM and aftermarket Ignition and Tune-Up Products don’t get more top quality, durable, and affordable than from the brands below.

Popular NGK 2021 Ford E-450 Super Duty Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2021 Ford E-450 Super Duty, using quality Ignition and Tune-Up Products is essential to ensure durability and a perfect fit. NGK ticks all of those boxes. We offer a wide selection of NGK Ignition and Tune-Up Products, specifically designed for the 2021 Ford E-450 Super Duty. With over 1 NGK brand Ignition and Tune-Up Products in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $14.99. Plus, with over 1 customer reviews and an average rating of 4.8 stars, you can trust that our NGK Ignition and Tune-Up Products will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
Ruthenium HX Spark Plug (LTR7BHX): High Ignitability & Durability
from $14.99
(1)
Ruthenium HX Spark Plug (LTR7BHX): High Ignitability & Durability
“I got these for my 2019 Mustang Ecoboost and these were way better spark plugs then anything i have tried definitely a performance oriented, spark plu”

Popular Autolite 2021 Ford E-450 Super Duty Ignition and Tune-Up Products

Autolite auto parts is one of the highest quality Ignition and Tune-Up Product brands in the market. Any 2021 Ford E-450 Super Duty owner should feel confident when installing genuine Autolite parts in their vehicle. To ensure the best fit and performance for your 2021 E-450 Super Duty, Advance Auto Parts carries a full inventory of 2 Autolite Ignition and Tune-Up Products. Plus you will be keeping your Ford in peak condition while saving money because prices on these Autolite Ignition and Tune-Up Products range from $6.99 to $10.99, plus, with more than 43 customer reviews and an impressive 4.6 stars average rating, you can be confident the Fram Ignition and Tune-Up Products below will deliver on both quality and value.
Double Platinum Spark Plug: Enhanced Durability & Performance
from $6.99
(2)
Double Platinum Spark Plug: Enhanced Durability & Performance
“Really tuned up the performance of the Ford 6.2 that we were working on.”
Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition
from $10.99
(41)
Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition
“Awesome quality plug and a decent price.”

FAQs for 2021 Ford E-450 Super Duty Ignition and Tune-Up Products

Which Ignition and Tune-Up Products are best-sellers for 2021 Ford E-450 Super Duties?

Out of 16 Ignition and Tune-Up Products that fit 2021 Ford E-450 Super Duties, the following parts are the top sellers:

What’s the price range for 2021 Ford E-450 Super Duty Ignition and Tune-Up Products?

Ignition and Tune-Up Product prices for the 2021 Ford E-450 Super Duty start at $6.99 and go up to $201.99 for the most premium parts.

What’s the average price of a Ignition and Tune-Up Product for a 2021 Ford E-450 Super Duty?

The average price for Ignition and Tune-Up Products for the 2021 Ford E-450 Super Duty is $39.76. Keep in mind the variety of part types within our Ignition and Tune-Up Product category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Ignition and Tune-Up Products for other Ford E-450 Super Duty model years?

Yes, we currently carry Ignition and Tune-Up Products for 20 model years of Ford E-450 Super Duties between 2003 and 2026. Ignition and Tune-Up Products are bought most frequently for the following model years: 2023, 2022, 2024, 2019, 2018, 2017, 2016, 2015, and 2014.

What are the cheapest Ignition and Tune-Up Products for my 2021 Ford E-450 Super Duty?

What are the top-rated Ignition and Tune-Up Products that fit the 2021 Ford E-450 Super Duty?

Out of 221 reviews by customers, our 2021 Ford E-450 Super Duty Ignition and Tune-Up Products have an average customer rating of . These are some of the highest-rated Ignition and Tune-Up Product types for the 2021 Ford E-450 Super Duty and their top-rated products:

What types of Ignition and Tune-Up Products do you sell for my 2021 Ford E-450 Super Duty?

As of 11/2/25, these are some of the most in-demand types of Ignition and Tune-Up Products for a 2021 Ford E-450 Super Duty:

Can I get help with 2021 Ford E-450 Super Duty Ignition and Tune-Up Product orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Ignition and Tune-Up Products and more.

What is your return policy for Ford E-450 Super Duty Ignition and Tune-Up Products?

Advance Auto Parts keeps returns simple. For new Ford E-450 Super Duty Ignition and Tune-Up Products and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.