2021 Ford E-450 Super Duty Differentials
Keep Your 2021 Ford E-450 Super Duty in Top Shape with Quality Differentials
Whether you’re repairing or upgrading your Differential, using high-quality parts is key to keeping your 2021 Ford E-450 Super Duty looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Differential Bearing Kits, Front Differential Pinion Bearings, and Differential Bearings. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.
Top-Rated Differentials from Trusted Brands
Looking for a reliable Differential? We’ve got you covered with options from brands you know and trust like DriveWorks. For example, DriveWorks Differentials start at just $11.99 with an average 4.3 star rating. With over 3 reviews and a solid 4 star average, you can shop with confidence knowing other Ford E-450 Super Duty owners approve.
Competitive Prices and Extensive Inventory
The average price for a 2021 Ford E-450 Super Duty Differential at Advance Auto Parts is around $149.09, with a range that starts at $8.89 and goes up to $556.99. With 4 options in stock from 3 trusted brands, finding the right fit is easy. Popular picks like Cup and Differential Repair Kit start at just $8.89 and offer a great balance of form and function.
Explore Related Parts
While you’re upgrading or replacing your Differential, don’t forget to check out other key components like Drive Shafts and Axles and Transfer Cases. At Advance Auto Parts, we’re here to help you keep your 2021 Ford E-450 Super Duty in peak condition, inside and out.
Find Your Specific 2021 Ford E-450 Super Duty Differentials
Looking for the perfect Differential for your 2021 Ford E-450 Super Duty? You’re in the right place. Below, you’ll find links to various types of Differentials that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Differentials, ensuring durability and a precise fit for your Ford E-450 Super Duty. Whether you’re driving a 2021 model or another popular model year like
2012,
2013,
2014,
2015,
2016,
2017,
2018,
2019, and
2022, we’ve got you covered. Purchasing Differentials from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Differentials that fit your vehicle.
Essential 2021 Ford E-450 Super Duty Differentials
National – Tapered Roller Bearing Cone (Part No.HM803149)
from
$36.99
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.
Product Features:
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Product Features:
- PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
- OE-STYLE DESIGN – Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Yukon Gear – Set Up Bearing (Part No.56045)
from
$153.99
M802048 set-up bearing (one bearing). No return.
Product Features:
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Product Features:
- Set up bearing
- Fits M802048 pinion bearing
- Easily slips on and off pinion journal to allow for easier pinion depth adjustment
National – Tapered Roller Bearing Cone (Part No.HM88542)
from
$23.49
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.
Product Features:
See More
Product Features:
- PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
- OE-STYLE DESIGN – Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
National – Multi-Purpose Bearing (Part No.A-59)
from
$202.99
Product Features:
See More
- CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
- PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
- OE-STYLE DESIGN: Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
National – Tapered Roller Bearing Cone (Part No.HM803146)
from
$38.49
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.
Product Features:
See More
Product Features:
- PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
- OE-STYLE DESIGN – Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Driveworks – Tapered Roller Bearing (Part No.S-HM-803110)
Yukon Gear – Set Up Bearing (Part No.56067)
from
$153.99
Set-up bearing (one bearing). HM803146. No return.
Product Features:
See More
Product Features:
- Set up bearing
- Fits HM803146 pinion bearing
- Easily slips on and off pinion journal to allow for pinion depth adjustment
FAG US – Cup (Part No.15245)
from
$8.89
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.
Product Features:
See More
Product Features:
- High-precision and High-quality components used in all KITs
- Coverage of classic and new high-tech solutions for the best system coverage
Yukon Gear – Set Up Bearing (Part No.56079)
from
$209.99
NO RETURN NP516549 SET-UP Bearing (1 SINGLE Bearing) for Dana 80 , 11.5AAM , 4.375″ OD .
Product Features:
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Product Features:
- Set up bearing
- Fits NP5516549 pinion bearing
- Easily slips on and off pinion journal to allow for pinion depth adjustment
Yukon Gear – Master Overhaul Kit For Dana 60 And 61 Rear Differential (Part No.14037)
from
$414.99
Yukon Master Overhaul kits give you all the high quality parts you need to start & finish every differential job. Yukon offers more tailor-made kits than any other manufacturer in the industry to meet your specific installation needs. This kit uses Timken bearings and races along with high quality seals and small parts. Included in this kit are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), Thread locking compound, marking compound with brush, and gasket. Yukon’s Master Overhaul kits are the most comprehensive and complete kits on the market. They do extensive research to ensure that every kit is specially tailored to your application.
Product Features:
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Product Features:
- Fits Dana Spicer 60 rear
- Included are Timken bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve , oil baffles and slingers , thread locker, marking compound with brush, and gasket.
Motive Gear – Differential Bearing Kit – Koyo (Part No.R80RA)
from
$258.99
Motive Gear Differential Bearing Kits Include Front & Rear Pinion Bearing, Pinion Seal, Carrier Bearings, Pilot Bearing Where Applicable, Gear Marking Compound, Crush Sleeve, Pinion Nut, Brush, Thread Locking Compound And Cover Gasket Or Rtv
Product Features:
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Product Features:
- BRG KIT 99 LATER DANA 80 FORD ONLY
Motive Gear – Differential Bearing Kit – Timken (Part No.R70HRT)
from
$174.99
Motive Gear Differential Bearing Kits Include Front & Rear Pinion Bearing, Pinion Seal, Carrier Bearings, Pilot Bearing Where Applicable, Gear Marking Compound, Crush Sleeve, Pinion Nut, Brush, Thread Locking Compound And Cover Gasket Or Rtv
Product Features:
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Product Features:
- KIT BRG & SEAL DANA 70 HD
Yukon Gear – Bearing Install Kit For ’08-’10 Ford 10.5" Differential (Part No.11120)
from
$514.99
Yukon Bearing installation kits are perfect for shops & builders who have shims on the shelf and are looking to save cost over a Master Overhaul kit. This kit uses Timken bearings and races along with all high quality small parts. kit includes carrier bearings and races, pinion bearings and races, pinion seal, crush sleeve (if applicable), oil baffles and slingers (if applicable), marking compound and brush. Yukon does extensive research for each application to make sure your kit will arrive with all the correct parts you need to install your ring & pinion set.
Product Features:
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Product Features:
- Fits2007-2010 Ford 10.5″ using aftermarket 10.25″ ring & pinion set
- Included are carrier bearings and races, pinion bearings and races, pinion seal, crush sleeve, marking compound and brush.
Motive Gear – Differential Master Bearing Kit – Timken (Part No.R80RAMKT)
from
$345.99
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
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Yukon Gear – Master Overhaul Kit For 2008-2010 Ford 10.5" Differentials Using Aftermarket 10.25" R&P Only (Part No.14151)
from
$699.99
Yukon Master Overhaul kits give you all the high quality parts you need to start & finish every differential job. Yukon offers more tailor-made kits than any other manufacturer in the industry to meet your specific installation needs. This kit uses Timken bearings and races along with high quality seals and small parts. Included in this kit are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), Thread locking compound, marking compound with brush, and gasket. Yukon’s Master Overhaul kits are the most comprehensive and complete kits on the market. They do extensive research to ensure that every kit is specially tailored to your application.
Product Features:
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Product Features:
- Fits 2007-2010 Ford 10.5″ housing with aftermarket 10.25″ ring and pinion set
- Included are Timken bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve , thread locker, marking compound with brush, and gasket.
- For use to install 10.25″ gears into 10.5″ housing
Yukon Gear – Bearing Install Kit For Dana 60 Rear Differential (Part No.11031)
from
$369.99
Yukon Bearing installation kits are perfect for shops & builders who have shims on the shelf and are looking to save cost over a Master Overhaul kit. This kit uses Timken bearings and races along with all high quality small parts. kit includes carrier bearings and races, pinion bearings and races, pinion seal, crush sleeve (if applicable), oil baffles and slingers (if applicable), marking compound and brush. Yukon does extensive research for each application to make sure your kit will arrive with all the correct parts you need to install your ring & pinion set.
Product Features:
See More
Product Features:
- Fits Dana Spicer 60 rear
- Included are carrier bearings and races, pinion bearings and races, pinion seal, crush sleeve , oil baffles and slingers , marking compound and brush.
Yukon Gear – Bearing Install Kit For Dana 80 (4.375" OD Only) Differential (Part No.11036)
from
$689.99
Yukon Bearing installation kits are perfect for shops & builders who have shims on the shelf and are looking to save cost over a Master Overhaul kit. This kit uses Timken bearings and races along with all high quality small parts. kit includes carrier bearings and races, pinion bearings and races, pinion seal, crush sleeve (if applicable), oil baffles and slingers (if applicable), marking compound and brush. Yukon does extensive research for each application to make sure your kit will arrive with all the correct parts you need to install your ring & pinion set.
Product Features:
See More
Product Features:
- Fits Dana Spicer 80 with 4.375″ O.D. pinion bearing
- Included are carrier bearings and races, pinion bearings and races, pinion seal, oil baffles and slingers , marking compound and brush.
Yukon Gear – Master Overhaul Kit For 2011 & Up Ford 10.5" Differentials Using OEM Ring & Pinion (Part No.14201)
from
$789.99
Yukon Master Overhaul kits give you all the high quality parts you need to start & finish every differential job. Yukon offers more tailor-made kits than any other manufacturer in the industry to meet your specific installation needs. This kit uses Timken bearings and races along with high quality seals and small parts. Included in this kit are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), Thread locking compound, marking compound with brush, and gasket. Yukon’s Master Overhaul kits are the most comprehensive and complete kits on the market. They do extensive research to ensure that every kit is specially tailored to your application.
Product Features:
See More
Product Features:
- Fits 2011 and up Ford 10.5″ housing with OEM ring and pinion set
- Included are Timken bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve, thread locker, marking compound with brush, and gasket.
National – Bearing Race (Part No.382A)
from
$10.99
Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.
Product Features:
See More
Product Features:
- PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION – Crowned raceways for even load distribution
- OE-STYLE DESIGN – Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Driveworks – Tapered Cone Wheel Bearing Assembly (Part No.S-387-AS)
from
$18.49
Value-priced bearing meets all cataloged application requirements.
Product Features:
See More
Product Features:
- Brand may vary by location
National – Tapered Roller Bearing Cone (Part No.LM104949)
from
$21.99
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.
Product Features:
See More
Product Features:
- PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
- OE-STYLE DESIGN – Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Driveworks – Taper Bearing Cone (Part No.S-LM-104949)
from
$11.99
Value-priced bearing meets all cataloged application requirements.
Product Features:
See More
Product Features:
- Brand may vary by location
National – Multi-Purpose Bearing (Part No.A-50)
from
$66.99
Product Features:
See More
- CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
- PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
- OE-STYLE DESIGN: Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Yukon Gear – 9.25" Chrysler, Dana 60 Semi-Float X/P Bolt, 80 & Up, 5/16" Head, Tapered Shoulder (Part No.33238)
National – Bearing Race (Part No.LM102910)
from
$7.79
Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.
Product Features:
See More
Product Features:
- PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
- SMOOTH ROTATION – Crowned raceways for even load distribution
- OE-STYLE DESIGN – Engineered to meet OE specifications
- COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Popular 2021 Ford E-450 Super Duty Differentials Categories
Most Popular Differential Bearing Kit for 2021 Ford E-450 Super Duties
Enhance your 2021 Ford E-450 Super Duty with this popular Differential Bearing Kit we have in stock, for $556.99.
LuK – Differential Repair Kit (Part No.GDK332-HD)
from
$556.99
Product Features:
See More
- Each LuK GearBOX contains all the OE quality bearings needed for a professional transmission repair
- LuK Differential Bearing Kits are designed to meet or exceed OEM requirements. This will ensure customer satisfaction.
- LuK Differential Bearing Kits contain the bearings and seals needed to complete the job.
- LuK Differential Bearing Kits include wear parts such as seals, O-rings, shaft sealing rings, support bearings and spare parts where necessary for eliminating the specific cause of failure.
Best-Selling 2021 Ford E-450 Super Duty Front Differential Pinion Bearing
Upgrade your E-450 Super Duty with our best-selling Front Differential Pinion Bearing.
FAG US – Cup (Part No.15245)
from
$8.89
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.
Product Features:
See More
Product Features:
- High-precision and High-quality components used in all KITs
- Coverage of classic and new high-tech solutions for the best system coverage
Top-Quality Differential Bearings for 2021 Ford E-450 Super Duties
Choose a high-quality OEM or aftermarket Differential Bearing for Ford E-450 Super Duties and enjoy top-notch performance from $11.99.
Driveworks – Taper Bearing Cone (Part No.S-LM-104949)
from
$11.99
Value-priced bearing meets all cataloged application requirements.
Product Features:
See More
Product Features:
- Brand may vary by location
Driveworks – Tapered Cone Wheel Bearing Assembly (Part No.S-387-AS)
from
$18.49
Value-priced bearing meets all cataloged application requirements.
Product Features:
See More
Product Features:
- Brand may vary by location
Top-Rated Differential Brands For Your 2021 Ford E-450 Super Duty
When it comes to finding the perfect Differential for your 2021 Ford E-450 Super Duty, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 3 trusted brands. We carry the most popular Differential brands including DriveWorks, and more, all known for their exceptional customer ratings (average brand rating of 4.3 stars) and competitive prices, as low as $11.99. Purchasing a Differential from us here at Advance Auto Parts is a smart move for both you and your 2021 Ford E-450 Super Duty, providing peace of mind with parts that meet or exceed OEM standards.
Popular DriveWorks 2021 Ford E-450 Super Duty Differentials
If you’re looking for a top-quality Differential for your 2021 Ford E-450 Super Duty, Advance Auto Parts has exactly what you need with our selection of DriveWorks Differentials. We have 2 DriveWorks Differentials in stock for this fitment, all known for their durability and precision fit. With prices starting at just $11.99 and an average cost of $15.24, you’ll find the perfect Differential for your needs and budget. DriveWorks Differentials for the 2021 Ford E-450 Super Duty come highly rated, with over 3 customer reviews and an impressive average rating of 4.3 stars. Choosing a DriveWorks Differential from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
FAQs for 2021 Ford E-450 Super Duty Differentials
What are the best-selling Differentials for 2021 Ford E-450 Super Duties?
Out of 4 Differentials that fit 2021 Ford E-450 Super Duties, the following parts are the top sellers:
- Cup (50206233) – $8.89
- Differential Repair Kit (50250198) – $556.99
What’s the price range for 2021 Ford E-450 Super Duty Differentials?
The prices of Differentials for the 2021 Ford E-450 Super Duty range from $8.89 up to $556.99 for the most premium parts.
What is the average price of a Differential for a 2021 Ford E-450 Super Duty?
The average price for Differentials for the 2021 Ford E-450 Super Duty is $149.09. Keep in mind the variety of part types within our Differential category, where you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Differentials for other Ford E-450 Super Duty model years?
What are the cheapest Differentials for my 2021 Ford E-450 Super Duty?
The cheapest 2021 Ford E-450 Super Duty Differentials we carry are:
- Cup (50206233) – $8.89
- Taper Bearing Cone (5050049) – $11.99
- Tapered Cone Wheel Bearing Assembly (5052270) – $18.49
- Differential Repair Kit (50250198) – $556.99
Does Advance Auto Parts sell Differentials for any other 2021 Ford models?
Yes. We stock Differentials for 18 other popular 2021 Ford models. Some of the most popular are 2021 F-150 Differentials, 2021 Mustang Differentials, 2021 Explorer Differentials, 2021 Bronco Differentials, and 2021 F-250 Super Duty Differentials.
What are the top-rated Differentials that fit the 2021 Ford E-450 Super Duty?
The one 2021 Ford E-450 Super Duty Differential we have in stock is the Cup. It costs $8.89.
What types of Differentials do you sell for my 2021 Ford E-450 Super Duty?
As of 11/2/25, these are some of the most in-demand types of Differentials for a 2021 Ford E-450 Super Duty:
Can I get help with 2021 Ford E-450 Super Duty Differential orders?
Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Differentials and more.
What is your return policy for Ford E-450 Super Duty Differentials?
Advance Auto Parts keeps returns simple. For new Ford E-450 Super Duty Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.