2021 Chevrolet Express 4500 Engine Gaskets and Seals

Keep Your 2021 Chevrolet Express 4500 in Top Shape with Quality Engine Gaskets and Seals

Whether you’re repairing or upgrading your Engine Gaskets and Seal, using high-quality parts is key to keeping your 2021 Chevrolet Express 4500 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Oil Pan Gaskets, Valve Cover Gaskets, and Fuel Pump Gaskets. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2021 Chevrolet Express 4500 Engine Gaskets and Seal at Advance Auto Parts is around $13.09, with a range that starts at $5.99 and goes up to $26.99. With 3 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like Engine Valve Cover Gasket Set, Oil Pan Gasket, and Fuel Pump Mounting Gasket start at just $5.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Gaskets and Seal, don’t forget to check out other key components like Camshafts and Engine Timing Parts. At Advance Auto Parts, we’re here to help you keep your 2021 Chevrolet Express 4500 in peak condition, inside and out.

Essential 2021 Chevrolet Express 4500 Engine Gaskets and Seals

Felpro – Fuel Pump Mounting Gasket (Part No.73158)

Fuel Pump Mounting Gasket

from

$5.99
Fuel Pump Mounting Gasket

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50681)

Engine Valve Cover Gasket Set

from

$64.99
Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50504 R)

Engine Valve Cover Gasket Set

from

$26.99
Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Dorman – Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces (Part No.904-380)

Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces

from

$91.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.

Product Features:
  • Direct replacement – this valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles
  • Ideal solution – engineered to help ensure a secure seal when an original gasket is due for service or damaged
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50813 R)

Engine Valve Cover Gasket Set

from

$112.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Felpro – VALVE COVER GASKET SET (Part No.VS 50821 R)

VALVE COVER GASKET SET

from

$203.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Dorman – Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces (Part No.904-171)

Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces

from

$136.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.

Product Features:
  • Direct replacement – this valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles
  • Ideal solution – engineered to help ensure a secure seal when an original gasket is due for service or damaged
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50684 R)

Engine Valve Cover Gasket Set

from

$99.99
Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Victor Reinz – Molded Rubber Valve Cover Gasket Set: Direct Fit, Includes Grommets, 36 Pieces (Part No.15-10905-01)

Molded Rubber Valve Cover Gasket Set: Direct Fit, Includes Grommets, 36 Pieces

from

$90.99
Oil drops on the driveway are a distant memory thanks to sophisticated engine valve cover and gasket designs. Victor Reinz is at the forefront of engineering the latest sealing technology. Although the primary task of valve cover gaskets is to seal oil and oil spray, they must withstand high temperatures brought on by nearby exhaust manifolds, exhaust crossovers in the cylinder heads, and EGR systems. Victor Reinz valve cover gaskets deliver the quality materials you demand. Where appropriate, Victor Reinz valve cover gaskets are designed with compression limiters to prevent over-torquing, splitting, or the need to retorque.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
  • Meets or exceeds OE specifications
  • Zero engine leakage for late model vehicles.
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50504 R-1)

Engine Valve Cover Gasket Set

from

$37.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50907 R)

Engine Valve Cover Gasket Set

from

$26.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL – Manufactured with rubber compounds to help ensure a consistent and long-life seal
  • PRECISE DESIGN – Engineered to work with the embossed cover and pan flanges
  • PREVENTS OVERTIGHTENING – Features compression limiters incorporated into the design to help eliminate overtightening (application specific)
  • OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
See More

GM Genuine Parts – Oil Pan Gasket (Part No.12612350)

Oil Pan Gasket

from

$65.99
GM Genuine Parts Engine Oil Pan Gaskets are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Felpro – Engine Oil Pan Gasket Set – PermaDry molded rubber (Part No.OS 30693 R)

Engine Oil Pan Gasket Set - PermaDry molded rubber

from

$67.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL – Manufactured with rubber compounds to ensure a consistent and long-life seal across the entire oil pan
  • PREVENTS OVERTIGHTENING – Torque limiters help eliminate overtightening and gasket splitting and extruding (where applicable)
  • OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • ENGINEERING EXPERTISE – Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
See More

Felpro – Engine Oil Pan Gasket Set – High-temperature Rubber-coated fiber (Part No.OS 30748)

Engine Oil Pan Gasket Set - High-temperature Rubber-coated fiber

from

$20.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL – Manufactured with rubber compounds to ensure a consistent and long-life seal across the entire oil pan
  • PREVENTS OVERTIGHTENING – Torque limiters help eliminate overtightening and gasket splitting and extruding (where applicable)
  • OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • ENGINEERING EXPERTISE – Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
  • ENGINEERING EXPERTISE – Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
See More

Victor Reinz – Engine Oil Pan Gasket Set (Part No.10-10238-01)

Engine Oil Pan Gasket Set

from

$33.99
Built to meet or exceed the standards of original equipment manufacturers around the world and avoid comebacks Victor Reinz oil pan gaskets deliver the seal that prevents drops on the driveway. Victor Reinz engineers select the best designs and materials for the specific application. The level of sophistication in oil pan gasket form and function has jumped greatly in recent years, with the gasket often being an integral part of the manufacturers efforts to control engine noise, vibration, and harshness (NVH). Only a company with innovative gasket technology can supply the right gasket for every application, new or old.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Felpro – Engine Oil Pan Gasket Set, 18 Bolt Hole, One Piece Gasket (Part No.OS 30838)

Engine Oil Pan Gasket Set, 18 Bolt Hole, One Piece Gasket

from

$19.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

GM Genuine Parts – Oil Pan Gasket (Part No.12666993)

Oil Pan Gasket

from

$6.29
GM Genuine Parts Engine Oil Pan Gaskets are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

MAHLE Original – Engine Oil Pan Gasket Set (Part No.OS32284)

Engine Oil Pan Gasket Set

from

$21.99
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • Oil pan gasket set contains all gaskets required.
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
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Most Popular Oil Pan Gasket for 2021 Chevrolet Express 4500s

Enhance your 2021 Chevrolet Express 4500 with this popular Oil Pan Gasket we have in stock, for $6.29.

GM Genuine Parts – Oil Pan Gasket (Part No.12666993)

Oil Pan Gasket

from

$6.29
GM Genuine Parts Engine Oil Pan Gaskets are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Best-Selling 2021 Chevrolet Express 4500 Valve Cover Gasket

Upgrade your Express 4500 with our best-selling Valve Cover Gasket.

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50907 R)

Engine Valve Cover Gasket Set

from

$26.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL – Manufactured with rubber compounds to help ensure a consistent and long-life seal
  • PRECISE DESIGN – Engineered to work with the embossed cover and pan flanges
  • PREVENTS OVERTIGHTENING – Features compression limiters incorporated into the design to help eliminate overtightening (application specific)
  • OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
See More

Top-Quality Fuel Pump Gaskets for 2021 Chevrolet Express 4500s

Choose a high-quality OEM or aftermarket Fuel Pump Gasket for Chevrolet Express 4500s and enjoy top-notch performance from $5.99.

Felpro – Fuel Pump Mounting Gasket (Part No.73158)

Fuel Pump Mounting Gasket

from

$5.99
Fuel Pump Mounting Gasket

FAQs for 2021 Chevrolet Express 4500 Engine Gaskets and Seals

What are the best-selling Engine Gaskets and Seals for 2021 Chevrolet Express 4500s?

Out of 3 Engine Gaskets and Seals that fit 2021 Chevrolet Express 4500s, the following parts are the top sellers:

What’s the price range for 2021 Chevrolet Express 4500 Engine Gaskets and Seals?

The prices of Engine Gaskets and Seals for the 2021 Chevrolet Express 4500 range from $5.99 up to $26.99 for the most premium parts.

What is the average price of an Engine Gaskets and Seal for a 2021 Chevrolet Express 4500?

The average price for Engine Gaskets and Seals for the 2021 Chevrolet Express 4500 is $13.09. Keep in mind the variety of part types within our Engine Gaskets and Seal category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Gaskets and Seals for other Chevrolet Express 4500 model years?

Yes, we carry Engine Gaskets and Seals for 15 model years of Chevrolet Express 4500s between 2009 and 2025. The following model years are the most popular for Engine Gaskets and Seal purchases: 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, and 2012.

What are the cheapest Engine Gaskets and Seals for my 2021 Chevrolet Express 4500?

The cheapest 2021 Chevrolet Express 4500 Engine Gaskets and Seals we carry are:

Does Advance Auto Parts sell Engine Gaskets and Seals for any other 2021 Chevrolet models?

What types of Engine Gaskets and Seals do you sell for my 2021 Chevrolet Express 4500?

As of 11/2/25, these are some of the most in-demand types of Engine Gaskets and Seals for a 2021 Chevrolet Express 4500:

Can I get help with 2021 Chevrolet Express 4500 Engine Gaskets and Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Chevrolet Engine Gaskets and Seals and more.

What is your return policy for Chevrolet Express 4500 Engine Gaskets and Seals?

Advance Auto Parts keeps returns simple. For new Chevrolet Express 4500 Engine Gaskets and Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.