2016 Ford E-350 Super Duty Engine Cooling Parts

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Keep Your 2016 Ford E-350 Super Duty in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2016 Ford E-350 Super Duty looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Thermostats, Water Pump Gaskets, and Radiators. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium, Felpro, and Dorman. For example, Carquest Premium Engine Cooling Parts start at just $14.99 with an average 4.4 star rating. Felpro and Dorman offer similar pricing and quality, backed by strong customer feedback. With over 1,695 reviews and a solid 4 star average, you can shop with confidence knowing other Ford E-350 Super Duty owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2016 Ford E-350 Super Duty Engine Cooling Part at Advance Auto Parts is around $78.87, with a range that starts at $2.99 and goes up to $416.99. With 39 options in stock from 9 trusted brands, finding the right fit is easy. Popular picks like Multi-Purpose O-Ring, High Flow Thermostat: 170 Degrees, and UltraStat Thermostat: 195 Degrees start at just $11.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Blend Doors and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2016 Ford E-350 Super Duty in peak condition, inside and out.

Essential 2016 Ford E-350 Super Duty Engine Cooling Parts

Felpro – Engine Water Pump O-Ring (Part No.35499)

Engine Water Pump O-Ring

from

$3.29
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Dorman – Pressurized Coolant Reservoir: White, Plastic, Original Equipment Replacement (Part No.603-029)

Pressurized Coolant Reservoir: White, Plastic, Original Equipment Replacement

from

$105.99
Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part
  • Ideal solution – engineered for a seamless installation
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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Dorman – Electronic Fan Clutch (Part No.622-102)

Electronic Fan Clutch

from

$331.99
This engine cooling fan clutch directly replaces the original equipment part on specified vehicles. It is engineered for durability and made of quality components to ensure proper cooling system operation when the original fan clutch has failed.

Product Features:
  • Ideal replacement – this cooling fan clutch directly replaces the original fan clutch on specified vehicle years, makes and models
  • Durable construction – this fan clutch is designed to withstand extreme temperature to ensure proper cooling system operation
  • Cost-effective solution – offers original equipment fit and function at a competitive price
  • Trustworthy quality – backed by a team of designers and engineers in the United States
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Motorcraft – Radiator Cap (Part No.RS-527)

Radiator Cap

from

$12.29
Radiator Cap

Felpro – Multi-Purpose O-Ring (Part No.35489)

Multi-Purpose O-Ring

from

$11.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Carquest Premium – Engine Water Pump: New (Part No.T4194)

Engine Water Pump: New

from

$129.99
This premium water pump uses new high-quality components and is designed to meet or exceed OE specifications. This pump is 100% tested to ensure quality. Bearings, gaskets, seals, impeller, hub and housing are all designed for long-lasting service life. All necessary gaskets and seals are included.

Product Features:
  • This pump is used on accessory belt driven applications
  • Used mostly on models equipped with a fan clutch
  • It is highly recommended that the fan clutch be replaced with the water pump
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • All gaskets or seals necessary for installation are supplied with pump
  • Additional Notes: Includes gasket
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Felpro – Engine Water Pump Gasket (Part No.35478)

Engine Water Pump Gasket

from

$7.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Motorad UltraStats – Thermostat: 192 Degrees (Part No.5378-192)

Thermostat: 192 Degrees

from

$36.99
UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resitance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components.

Product Features:
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
See More

US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1064)

Water Pump with Fan Clutch

from

$189.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
See More

US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1024)

Water Pump with Fan Clutch

from

$263.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
See More

Carquest Premium – Radiator Cap Tester Adapter (Part No.12029)

Radiator Cap Tester Adapter

from

$41.99
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive coolant caps.

Product Features:
  • Machined metal construction
  • Works with MT-300 pressure tester
  • Tests coolant caps
  • Professional quality
See More

Edelbrock – Waterneck for Small Block Ford (Part No.48143)

Waterneck for Small Block Ford

from

$25.49
Edelbrock part No. 48143 Waterneck is designed for use with small-block Ford V8 engine applications. This Black water neck is a great way to finish off your engine. It features a 15 deg. neck and O-ring design for an improved seal, which also allows for removal without requiring a new gasket. Fits any 1-1/2″ diameter outlet hose.
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Carquest Premium – Radiator (Part No.431359)

Radiator

from

$327.99
Carquest Premium Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Carquest Premium Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.

Product Features:
  • Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
  • Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
  • Our fin edges are folded for increased stability and heat disbursement properties.
  • Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
  • Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
  • We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
  • We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.434080)

Radiator: With Transmission Oil Cooler

from

$416.99
Carquest Premium Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Carquest Premium Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.

Product Features:
  • Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
  • Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
  • Our fin edges are folded for increased stability and heat disbursement properties.
  • Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
  • Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
  • We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
  • We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
See More

Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54208)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$16.99
Cracked or lost the original engine coolant reservoir cap- Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
See More

Carquest Premium – Standard Reservoir Cap: 16 PSI (Part No.10238)

Standard Reservoir Cap: 16 PSI

from

$10.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Dorman – Clutch Fan Blade: Plastic, Cost Effective and Reliable (Part No.620-159)

Clutch Fan Blade: Plastic, Cost Effective and Reliable

from

$101.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Dorman – Clutch Fan Blade: Plastic, Cost Effective and Reliable (Part No.620-163)

Clutch Fan Blade: Plastic, Cost Effective and Reliable

from

$96.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
See More

Carquest Premium – Coolant Housing/Water Outlet: Gasket Included (Part No.85001)

Coolant Housing/Water Outlet: Gasket Included

from

$45.99
We are proud to offer this Carquest product line: Carquest Water Outlets. Our products are engineered and tested to provide years of trouble free operation and designed to be hassle free OE replacement part that meets and/or exceeds OE standards. Backed by over 50 years of mobile temperature control experience, fix it once and fix it right with CARQUST Water Outlets and Thermostat Housings.

Product Features:
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable))
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • Direct-fit replacement for ease of installation
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable)
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • Direct-fit replacement for ease of installation
See More

Dorman – Engine Coolant Water Outlet (Part No.902-1108)

Engine Coolant Water Outlet

from

$79.99
This replacement engine coolant water outlet is engineered to match the fit and durability of the stock engine coolant water outlet on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant water outlet directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement water outlets
See More

Motorcraft – THERMOSTAT O-RING (Part No.RG-571)

THERMOSTAT O-RING

from

$2.99
THERMOSTAT O-RING

Felpro – Multi-Purpose O-Ring (Part No.35759)

Multi-Purpose O-Ring

from

$2.79
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 192 Degrees (Part No.5190KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 192 Degrees

from

$44.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


    Product Features:
    • High grade stainless steel and copper construction
    • Meets or exceeds OEM standards
    • Consistent and precise response to cooling system needs
    • Original equipment design for worry-free direct fit replacement
    • 100% tested and calibrated
See More

Carquest Premium – Integrated Thermostat Housing: With Seal, 192 Degrees (Part No.14899)

Integrated Thermostat Housing: With Seal, 192 Degrees

from

$30.49
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees (Part No.5002KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees

from

$35.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


    Product Features:
    • High grade stainless steel and copper construction
    • Meets or exceeds OEM standards
    • Consistent and precise response to cooling system needs
    • Original equipment design for worry-free direct fit replacement
    • 100% tested and calibrated
See More

Dorman – Help – Radiator Drain Cocks (Part No.61127)

Radiator Drain Cocks

from

$7.49
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.

Product Features:
  • Direct replacement – this radiator drain petcock matches the fit and function of the original equipment part
  • Durable construction – this part is made of quality materials for a long service life
  • Saves money – offers original equipment quality at a competitive price
  • Quality assured – this petcock has undergone virtual testing to assure proper fit and function
See More

Most Popular Thermostats for 2016 Ford E-350 Super Duties

Enhance your 2016 Ford E-350 Super Duty with one of the 9 Thermostats we have in stock, starting at just $12.99.

Carquest Premium – Standard Thermostat: 195 Degrees (Part No.13779)

Standard Thermostat: 195 Degrees

from

$16.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – High Flow Thermostat: 170 Degrees (Part No.13967)

High Flow Thermostat: 170 Degrees

from

$14.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • Larger opening for increased coolant flow
  • Increased strength and durability
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: 180 Degrees (Part No.13778)

Standard Thermostat: 180 Degrees

from

$15.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad UltraStats – UltraStat Thermostat: 180 Degrees (Part No.5228-180JV)

UltraStat Thermostat: 180 Degrees

from

$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
See More

Carquest Premium – High Flow Thermostat: 180 Degrees (Part No.13968)

High Flow Thermostat: 180 Degrees

from

$12.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • Larger opening for increased coolant flow
  • Increased strength and durability
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: 195 Degrees (Part No.14989)

Standard Thermostat: 195 Degrees

from

$16.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium Stats – High Flow Thermostat: 180 Degrees (Part No.45778)

High Flow Thermostat: 180 Degrees

from

$15.79
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad UltraStats – UltraStat Thermostat: 195 Degrees (Part No.5228-195JV)

UltraStat Thermostat: 195 Degrees

from

$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
See More

Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 185 Degrees (Part No.5004KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 185 Degrees

from

$40.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Best-Selling 2016 Ford E-350 Super Duty Water Pump Gasket

Upgrade your E-350 Super Duty with our best-selling Water Pump Gasket with a 4 Starts rating across 11 reviews.

Felpro – Engine Water Pump Gasket (Part No.35478)

Engine Water Pump Gasket

from

$7.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Top-Quality Radiators for 2016 Ford E-350 Super Duties

Choose a high-quality OEM or aftermarket Radiator for Ford E-350 Super Duties and enjoy top-notch performance from $327.99.

Carquest Premium – Radiator (Part No.431359)

Radiator

from

$327.99
Carquest Premium Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Carquest Premium Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.

Product Features:
  • Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
  • Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
  • Our fin edges are folded for increased stability and heat disbursement properties.
  • Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
  • Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
  • We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
  • We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.434080)

Radiator: With Transmission Oil Cooler

from

$416.99
Carquest Premium Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Carquest Premium Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.

Product Features:
  • Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
  • Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
  • Our fin edges are folded for increased stability and heat disbursement properties.
  • Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
  • Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
  • We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
  • We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
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Our Top Pick for a 2016 Ford E-350 Super Duty Thermostat and Water Outlet Assembly

Invest in a durable Thermostat and Water Outlet Assembly for your 2016 Ford, knowing you’re getting trusted brands and expert craftsmanship.

Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees (Part No.5002KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees

from

$35.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Top-Rated Water Pumps for 2016 Ford E-350 Super Duties

Make a smart move for your 2016 Ford E-350 Super Duty with products all priced from $56.99 to $215.99.

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T4207)

Engine Water Pump: New, Gasket/Seals Included

from

$124.99
This premium water pump uses new high-quality components and is designed to meet or exceed OE specifications. This pump is 100% tested to ensure quality. Bearings, gaskets, seals, impeller, hub and housing are all designed for long-lasting service life. All necessary gaskets and seals are included.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
  • Additional Notes: Includes gasket
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Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T4196)

Engine Water Pump: New, Gasket/Seals Included

from

$56.99
This premium water pump uses new high-quality components and is designed to meet or exceed OE specifications. This pump is 100% tested to ensure quality. Bearings, gaskets, seals, impeller, hub and housing are all designed for long-lasting service life. All necessary gaskets and seals are included.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
  • Additional Notes: Includes gasket
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Carquest Premium – Engine Water Pump: New (Part No.T4194)

Engine Water Pump: New

from

$129.99
This premium water pump uses new high-quality components and is designed to meet or exceed OE specifications. This pump is 100% tested to ensure quality. Bearings, gaskets, seals, impeller, hub and housing are all designed for long-lasting service life. All necessary gaskets and seals are included.

Product Features:
  • This pump is used on accessory belt driven applications
  • Used mostly on models equipped with a fan clutch
  • It is highly recommended that the fan clutch be replaced with the water pump
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • All gaskets or seals necessary for installation are supplied with pump
  • Additional Notes: Includes gasket
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Motorcraft – ENGINE WATER PUMP (Part No.PW-423)

ENGINE WATER PUMP

from

$124.99
ENGINE WATER PUMP

Motorcraft – ENGINE WATER PUMP (Part No.PW-494)

ENGINE WATER PUMP

from

$175.99
ENGINE WATER PUMP

Motorcraft – Engine Water Pump (Part No.PW-684)

Engine Water Pump

from

$215.99
Motorcraft parts are recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:
  • Coolant reservoir keeps normal cold-start weepage out of sight and extends bearing life.
  • Press tubes are coated with nickel zinc for better housing connection and corrosion resistance.
  • Powdered-metallic hub mating surfaces provide superior alignment for smooth operation and do not need machining.
  • Robust impeller design is engineered to optimize performance for specific vehicle applications.
  • Durability tested to a 10 year/150,000 mile lifetime equivalent.
  • All pumps contain precision bearings with ground shafts to help deliver long life and efficient performance.
  • Bearing housing meets original equipment load requirements.
  • Bearings are locked into place to minimize fan-load vibration and help ensure long-term alignment and reliability.
  • Motorcraft Water Pumps are engineered to provide original equipment performance and reliability even in extreme conditions.
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Motorcraft – New Water Pump (Part No.PW-700)

New Water Pump

from

$74.99
Product Features:
  • Backed by the Motorcraft Service Parts Warranty. Warranty is supported nationwide by Ford/Lincoln dealers and Ford Authorized Distributors.
  • Coolant reservoir keeps normal cold-start weepage out of sight and extends bearing life.
  • Press tubes are coated with nickel zinc for better housing connection and corrosion resistance.
  • Powdered-metallic hub mating surfaces provide superior alignment for smooth operation and do not need machining.
  • Robust impeller design is engineered to optimize performance for specific vehicle applications.
  • Durability tested to a 10 year/150,000 mile lifetime equivalent.
  • All pumps contain precision bearings with ground shafts to help deliver long life and efficient performance.
  • Bearing housing meets original equipment load requirements.
  • Bearings are locked into place to minimize fan-load vibration and help ensure long-term alignment and reliability.
See More

Top-Rated Engine Cooling Part Brands For Your 2016 Ford E-350 Super Duty

When it comes to finding the perfect Engine Cooling Part for your 2016 Ford E-350 Super Duty, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 9 trusted brands. We carry the most popular Engine Cooling Part brands including Felpro, Carquest Premium, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $7.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2016 Ford E-350 Super Duty, providing peace of mind with parts that meet or exceed OEM standards.

Popular Felpro 2016 Ford E-350 Super Duty Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2016 Ford E-350 Super Duty, Advance Auto Parts has exactly what you need with our selection of Felpro Engine Cooling Parts. We have 3 Felpro Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $7.99 and an average cost of $9.32, you’ll find the perfect Engine Cooling Part for your needs and budget. Felpro Engine Cooling Parts for the 2016 Ford E-350 Super Duty come highly rated, with over 122 customer reviews and an impressive average rating of 4.6 stars. Choosing a Felpro Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Engine Water Pump Gasket
from $7.99
(11)
Engine Water Pump Gasket
“Perfect fit !”
Engine Water Pump Bypass Pipe O-Ring Kit
from $7.99
(1)
Engine Water Pump Bypass Pipe O-Ring Kit
“It was just what I needed”
Multi-Purpose O-Ring
from $11.99
(110)
Multi-Purpose O-Ring
“It work and price was reasonable”

Top-Quality Carquest Premium 2016 Ford E-350 Super Duty Engine Cooling Parts

For those in search of a high-quality Engine Cooling Part for their 2016 Ford E-350 Super Duty, Advance Auto Parts offers a great selection of Carquest Premium Engine Cooling Parts. With 3 Carquest Premium Engine Cooling Parts in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Engine Cooling Parts start at just $14.99, with an average price of $15.99, giving you a range of options to suit your budget. Backed by over 88 customer ratings and an average rating of 4.4 stars, Carquest Premium Engine Cooling Parts provide both reliability and excellent performance. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
High Flow Thermostat: 170 Degrees
from $14.99
(16)
High Flow Thermostat: 170 Degrees
“Great fit . Works properly so far so good”
Standard Thermostat: 180 Degrees
from $15.99
(16)
Standard Thermostat: 180 Degrees
“Car did not run hot, but lower radiator hose started leaking and was too hot to touch. Replaced and lower radiator hose temp was much cooler. Car runs”
Standard Thermostat: 195 Degrees
from $16.99
(56)
Standard Thermostat: 195 Degrees
“great”

FAQs for 2016 Ford E-350 Super Duty Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2016 Ford E-350 Super Duties?

Out of 39 Engine Cooling Parts that fit 2016 Ford E-350 Super Duties, the following parts are the top sellers:

What’s the price range for 2016 Ford E-350 Super Duty Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2016 Ford E-350 Super Duty range from $2.99 up to $416.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2016 Ford E-350 Super Duty?

The average price for Engine Cooling Parts for the 2016 Ford E-350 Super Duty is $78.87. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Ford E-350 Super Duty model years?

Yes, we carry Engine Cooling Parts for 24 model years of Ford E-350 Super Duties between 2000 and 2026. The following model years are the most popular for Engine Cooling Part purchases: 2022, 2021, 2019, 2018, 2017, 2015, 2014, 2013, and 2012.

What are the cheapest Engine Cooling Parts for my 2016 Ford E-350 Super Duty?

The cheapest 2016 Ford E-350 Super Duty Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2016 Ford models?

What are the top-rated Engine Cooling Parts that fit the 2016 Ford E-350 Super Duty?

The one 2016 Ford E-350 Super Duty Engine Cooling Part we have in stock is the THERMOSTAT O-RING. It costs $2.99.

What types of Engine Cooling Parts do you sell for my 2016 Ford E-350 Super Duty?

As of 3/1/26, these are some of the most in-demand types of Engine Cooling Parts for a 2016 Ford E-350 Super Duty:

Can I get help with 2016 Ford E-350 Super Duty Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Engine Cooling Parts and more.

What is your return policy for Ford E-350 Super Duty Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Ford E-350 Super Duty Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.