2012 Lexus IS250 Drivetrains

Essential Drivetrains for 2012 Lexus IS250s

Valvoline – High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon (Part No.773732)

High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon

from

$32.99
Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:
  • HIGH PERFORMANCE EXTREME-PRESSURE ADDITIVES HELP MINIMIZE WEAR in high pressure and high temperature conditions
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION can easily handle both winter and summer conditions for dependable coverage and protection year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • SUPERIOR ADDITIVES help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.10114-042B)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$12.79
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6098)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$134.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to LEXUS 05-20;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 2005-2020
  • Weight approx: 2 Lbs
  • BEARING ID / BORE: 1.1811 INCH / 30 MM
  • CENTERLINE: 0.10 INCH / 3 MM
  • MOUNT WIDTH: 5.75 INCH / 146 MM
See More

Timken – Wheel Hub Assembly (Part No.K7001176484TIM)

Wheel Hub Assembly

from

$312.23
Timken Wheel Hub Assembly is a single integrated unit that can be bolted directly onto corners, eliminating the need for conventional components like washers, spacers and nuts. Its design provides for lower total system cost, improved performance, reduced weight and lower warranty costs. The Formed Hub utilizes fewer components over conventional 4 x 2 designs, simplifying installation and reducing costs.

Product Features:
  • Allows the same configuration to be used on driven and non-driven wheels, replacing the conventional 4×2 (dead) spindle.
  • Features an advanced sensor and sensor technology for superb performance.
  • Holds bearing setting more consistently than traditional thread and nut designs. The resulting system stiffness reduces rotor run-out and improves brake performance.
  • Reduces weight by up to 20% per assembly compared to conventional wheel end solutions.
  • Features an active sensor capable of sensing down to zero speed. Sensor’s speed information can be used for vehicle dynamics control systems, speed control, speedometer, odometer, trip computer and other purposes.
  • Internally-mounted sensor protects against the elements, which ultimately reduces warranty costs. SENSOR-PAC also utilizes very small sensor-to-target wheel gaps, enabling a much smaller and more cost- effective sensor.
  • Includes an internally-mounted sensor that protects against debris, corrosion, thermal shock, and other hazards that threaten externally-mounted sensors.
  • Designed for superior performance in a minimal space. Timken engineers have packaged the sensor within the bearing without increasing overall dimensions to promote high performance and equal load carrying capacity in a minimum space.
See More

EMPI – Axle Shaft Nut (Part No.K403059357EMP)

Axle Shaft Nut

from

$5.11
The EMPI Axle Shaft Nut is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

Dorman – Spindle Nut (Part No.K1002751713DOR)

Spindle Nut

from

$17.46
Spindle Nut

National – Shaft Repair Sleeve (Part No.99166)

Shaft Repair Sleeve

from

$34.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

Needa Parts – Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack (Part No.090-030)

Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack

from

$6.79
This engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles. It is engineered to replace a missing or damaged plug & help ensure a secure seal.

Product Features:
  • Direct replacement – this engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles.
  • Ideal solution – engineered to replace a missing or damaged plug and help ensure a secure seal
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

National – Multi Purpose Seal (Part No.710416)

Multi Purpose Seal

from

$7.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Autopart International Inc – Axle Assembly (Part No.K40003009287API)

Axle Assembly

from

$149.66
Axle Assembly

Autopart International Inc – Axle Assembly (Part No.K40003009279API)

Axle Assembly

from

$120.91
Axle Assembly

National – Shaft Repair Sleeve (Part No.99134)

Shaft Repair Sleeve

from

$33.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

Corteco – Diff. Side Cover Sea (Part No.J7041183491CFW)

Diff. Side Cover Sea

from

$19.78
Diff. Side Cover Sea

Dorman – Spindle Nut M22-1.50 Hex Star Pattern (sold by each) (Part No.615-224)

Spindle Nut M22-1.50 Hex Star Pattern (sold by each)

from

$8.49
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

EMPI – RE CV Joint Boot Kit (Part No.K6010455696EMP)

RE CV Joint Boot Kit

from

$30.29
With Clamps and Grease The EMPIRE CV Joint Boot Kit is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function. Install one boot kit per wheel to restore vehicle to optimal condition and protect the constant velocity joint from contamination

Product Features:
  • Help restore the vehicle to like-new condition
  • Constructed of high strength OE materials
  • Resists environmental contamination
  • Protects the CV joint from premature failure
See More

Beck/Arnley – Cu Boot Kit (Part No.103-2565)

Cu Boot Kit

from

$31.49
Beck/Arnley parts meet foreign nameplate OE specifications for form, fit and function. Our product specialists work with a network of global sourcing partners so you can install the right part with confidence.

Product Features:
  • Matches OE form, fit and function
  • One piece neoprene boot
  • Kit complete with boot, grease, and hardware for complete installation
  • Hardware matches original design requirements
  • Application specific for this vehicle
See More

Dorman – Rear Drive Shaft (Part No.986-148)

Rear Drive Shaft

from

$1055.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Rear Drive Shaft: Adjustable (Part No.976-759)

Rear Drive Shaft: Adjustable

from

$893.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Rear Drive Shaft (Part No.986-166)

Rear Drive Shaft

from

$1022.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Corteco – Pinion Seal (Part No.J7010183495CFW)

Pinion Seal

from

$17.78
Pinion Seal

Upgrade your 2012 Lexus IS250 with Top-Quality Drivetrains

When it comes to maintaining or upgrading your 2012 Lexus IS250, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Drivetrains are key to keeping your IS250 functioning at its best. At Advance Auto Parts, we offer a wide selection of 23 Drivetrains for the 2012 Lexus IS250, designed to meet your needs without breaking the bank. From CV Axles and Joint replacements to Spindles upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Drivetrains for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Drivetrains for your 2012 Lexus IS250 at great prices. Our Drivetrains inventory for this model ranges from just $5.11 to $1,055.99, with an average price of $133.85. Our 23 Drivetrains in stock come from 12 trusted brands, so you’re sure to find the right part for your 2012 Lexus IS250 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2012 Lexus IS250, we stock popular OEM and aftermarket Drivetrains from top names like Valvoline, and more. Valvoline Drivetrains start at just $12.49 and boast an impressive 5 stars average rating from customers. With 237 customer reviews and counting, our 2012 Lexus IS250 Drivetrains have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Drivetrain upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2012 Lexus IS250 is always ready to roll. We’re committed to providing you with everything you need to keep your IS250 in top shape, all in one place. Start shopping confidently below for your 2012 Lexus IS250!

Best-Selling CV Axles and Joints for 2012 Lexus IS250s

Enhance the driving experience in your Lexus with 2 quality CV Axles and Joint components, starting at $30.29.

Beck/Arnley – Cu Boot Kit (Part No.103-2565)

Cu Boot Kit

from

$31.49
Beck/Arnley parts meet foreign nameplate OE specifications for form, fit and function. Our product specialists work with a network of global sourcing partners so you can install the right part with confidence.

Product Features:
  • Matches OE form, fit and function
  • One piece neoprene boot
  • Kit complete with boot, grease, and hardware for complete installation
  • Hardware matches original design requirements
  • Application specific for this vehicle
See More

EMPI – RE CV Joint Boot Kit (Part No.K6010455696EMP)

RE CV Joint Boot Kit

from

$30.29
With Clamps and Grease The EMPIRE CV Joint Boot Kit is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function. Install one boot kit per wheel to restore vehicle to optimal condition and protect the constant velocity joint from contamination

Product Features:
  • Help restore the vehicle to like-new condition
  • Constructed of high strength OE materials
  • Resists environmental contamination
  • Protects the CV joint from premature failure
See More

Most Popular 2012 Lexus IS250 Spindles

Customize your Lexus with 1 Spindles products like Spindle Lock Nuts, all priced under $8.49.

Dorman – Spindle Nut M22-1.50 Hex Star Pattern (sold by each) (Part No.615-224)

Spindle Nut M22-1.50 Hex Star Pattern (sold by each)

from

$8.49
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Top Picks for 2012 Lexus IS250 Differentials

Upgrade Lexus IS250s with top-quality Differentials parts, including 6 OEM and aftermarket selections for your 2012 model.

Valvoline – High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon (Part No.773732)

High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon

from

$32.99
Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:
  • HIGH PERFORMANCE EXTREME-PRESSURE ADDITIVES HELP MINIMIZE WEAR in high pressure and high temperature conditions
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION can easily handle both winter and summer conditions for dependable coverage and protection year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • SUPERIOR ADDITIVES help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.30040096-75000C)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$14.49
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.10114-042B)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$12.79
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Needa Parts – Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack (Part No.090-030)

Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack

from

$6.79
This engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles. It is engineered to replace a missing or damaged plug & help ensure a secure seal.

Product Features:
  • Direct replacement – this engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles.
  • Ideal solution – engineered to replace a missing or damaged plug and help ensure a secure seal
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

Corteco – Pinion Seal (Part No.J7010183495CFW)

Pinion Seal

from

$17.78
Pinion Seal

Valvoline – High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart (Part No.VV820)

High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart

from

$12.49
Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:
  • HIGH PERFORMANCE EXTREME-PRESSURE ADDITIVES HELP MINIMIZE WEAR in high pressure and high temperature conditions
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION can easily handle both winter and summer conditions for dependable coverage and protection year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • SUPERIOR ADDITIVES help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions
See More

In-Demand Transfer Cases for 2012 Lexus IS250s

Select from 2 premium Transfer Cases parts for your 2012 Lexus IS250, with prices ranging from $7.49 to $33.99.

National – Shaft Repair Sleeve (Part No.99134)

Shaft Repair Sleeve

from

$33.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

National – Multi Purpose Seal (Part No.710416)

Multi Purpose Seal

from

$7.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Most Sold 2012 Lexus IS250 Drive Shafts and Axles

Explore our best-selling Lexus parts for the 2012 IS250 among 11 OEM and aftermarket options starting from $5.11.

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV546206)

CV Axle Shaft Assembly

from

$101.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV546200)

CV Axle Shaft Assembly

from

$152.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Corteco – Diff. Side Cover Sea (Part No.J7041183491CFW)

Diff. Side Cover Sea

from

$19.78
Diff. Side Cover Sea

National – Shaft Repair Sleeve (Part No.99166)

Shaft Repair Sleeve

from

$34.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

Dorman – Spindle Nut (Part No.K1002751713DOR)

Spindle Nut

from

$17.46
Spindle Nut

Dorman – Rear Drive Shaft (Part No.986-148)

Rear Drive Shaft

from

$1055.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Rear Drive Shaft: Adjustable (Part No.976-759)

Rear Drive Shaft: Adjustable

from

$893.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Autopart International Inc – Axle Assembly (Part No.K40003009287API)

Axle Assembly

from

$149.66
Axle Assembly

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6098)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$134.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to LEXUS 05-20;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 2005-2020
  • Weight approx: 2 Lbs
  • BEARING ID / BORE: 1.1811 INCH / 30 MM
  • CENTERLINE: 0.10 INCH / 3 MM
  • MOUNT WIDTH: 5.75 INCH / 146 MM
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Autopart International Inc – Axle Assembly (Part No.K40003009279API)

Axle Assembly

from

$120.91
Axle Assembly

EMPI – Axle Shaft Nut (Part No.K403059357EMP)

Axle Shaft Nut

from

$5.11
The EMPI Axle Shaft Nut is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
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Top-Rated Drivetrains Brands For Your 2012 Lexus IS250

Shop for the best-rated brands offering Drivetrains and other products for your 2012 Lexus IS250s. Below you’ll find some of our best rated Drivetrains from Valvoline, and more. Drivetrains from these brands that fit a 2012 IS250 start at just $12.49 and are rated as high as 5 stars. OEM and aftermarket Drivetrains don’t get more top quality, durable, and affordable than from the brands below.

Popular Valvoline 2012 Lexus IS250 Drivetrains

When it comes to maintaining or upgrading your 2012 Lexus IS250, using quality Drivetrains is essential to ensure durability and a perfect fit. Valvoline ticks all of those boxes. We offer a wide selection of Valvoline Drivetrains, specifically designed for the 2012 Lexus IS250. With over 2 Valvoline brand Drivetrains in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $12.49, with an average price of just $22.74. Plus, with over 235 customer reviews and an average rating of 5 stars, you can trust that our Valvoline Drivetrains will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

FAQs for 2012 Lexus IS250 Drivetrains

Which Drivetrains are best-sellers for 2012 Lexus IS250s?

Out of 23 Drivetrains that fit 2012 Lexus IS250s, the following parts are the top sellers:

What’s the price range for 2012 Lexus IS250 Drivetrains?

Drivetrain prices for the 2012 Lexus IS250 start at $5.11 and go up to $1,055.99 for the most premium parts.

What’s the average price of a Drivetrain for a 2012 Lexus IS250?

The average price for Drivetrains for the 2012 Lexus IS250 is $133.85. Keep in mind the variety of part types within our Drivetrain category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drivetrains for other Lexus IS250 model years?

Yes, we currently carry Drivetrains for 9 model years of Lexus IS250s between 2006 and 2015. Drivetrains are bought most frequently for the following model years: 2015, 2014, 2013, 2011, 2010, 2009, 2008, 2007, and 2006.

What are the cheapest Drivetrains for my 2012 Lexus IS250?

The cheapest 2012 Lexus IS250 Drivetrains we carry in stock are:

What are the top-rated Drivetrains that fit the 2012 Lexus IS250?

Out of 237 reviews by customers, our 2012 Lexus IS250 Drivetrains have an average customer rating of . These are some of the highest-rated Drivetrain types for the 2012 Lexus IS250 and their top-rated products:

What types of Drivetrains do you sell for my 2012 Lexus IS250?

As of 2/5/25, these are some of the most in-demand types of Drivetrains for a 2012 Lexus IS250:

Can I get help with 2012 Lexus IS250 Drivetrain orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Drivetrains and more.

What is your return policy for Lexus IS250 Drivetrains?

Advance Auto Parts keeps returns simple. For new Lexus IS250 Drivetrains and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.