2010 Lexus IS250 Transmission Seals
Keep Your 2010 Lexus IS250 in Top Shape with Quality Transmission Seals
Whether you’re repairing or upgrading your Transmission Seal, using high-quality parts is key to keeping your 2010 Lexus IS250 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Miscellaneous Shift Shaft Seals, Shaft Seals, and Extension Housing Seals. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.
Competitive Prices and Extensive Inventory
The average price for a 2010 Lexus IS250 Transmission Seal at Advance Auto Parts is around $8.54, with a range that starts at $4.49 and goes up to $11.99. With 6 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like Multi Purpose Seal, Multi-Purpose Seal, and Multi-Purpose Seal start at just $7.99 and offer a great balance of form and function.
Explore Related Parts
While you’re upgrading or replacing your Transmission Seal, don’t forget to check out other key components like Automatic Transmission Pan and Gaskets and Automatic Transmission Parts. At Advance Auto Parts, we’re here to help you keep your 2010 Lexus IS250 in peak condition, inside and out.
Find Your Specific 2010 Lexus IS250 Transmission Seals
Looking for the perfect Transmission Seal for your 2010 Lexus IS250? You’re in the right place. Below, you’ll find links to various types of Transmission Seals that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Transmission Seals, ensuring durability and a precise fit for your Lexus IS250. Whether you’re driving a 2010 model or another popular model year like
2006,
2007,
2008,
2009,
2011,
2012,
2013,
2014, and
2015, we’ve got you covered. Purchasing Transmission Seals from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Transmission Seals that fit your vehicle.
Essential 2010 Lexus IS250 Transmission Seals
National – Multi Purpose Seal (Part No.221207)
from
$10.99
Product Features:
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- Design type: spring loaded; single-lip
- Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
- Good low temperature capability
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
National – Multi-Purpose Seal (Part No.710689)
from
$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
- Resistance to EP lubricants
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)
National – Multi-Purpose Seal (Part No.710416)
from
$9.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; single-lip
- Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
- Good low temperature capability
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
ATP – AT EXT HOUSING SEAL (Part No.RO-77)
from
$19.99
AT EXT HOUSING SEAL
Driveworks – Auto Transmission Extension Housing Seal (Rear Seal) (Part No.S-224205)
National – Multi-Purpose Seal (Part No.224205)
from
$7.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
- Resistance to EP lubricants
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
Popular 2010 Lexus IS250 Transmission Seals Categories
Most Popular Miscellaneous Shift Shaft Seal for 2010 Lexus IS250s
Enhance your 2010 Lexus IS250 with this popular Miscellaneous Shift Shaft Seal we have in stock, for $10.99.
National – Multi Purpose Seal (Part No.221207)
from
$10.99
Product Features:
See More
- Design type: spring loaded; single-lip
- Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
- Good low temperature capability
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
Best-Selling 2010 Lexus IS250 Shaft Seal
Upgrade your IS250 with our best-selling Shaft Seal.
Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)
Top-Quality Extension Housing Seals for 2010 Lexus IS250s
Choose a high-quality OEM or aftermarket Extension Housing Seal for Lexus IS250s and enjoy top-notch performance from $4.49.
National – Multi-Purpose Seal (Part No.224205)
from
$7.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
- Resistance to EP lubricants
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
Driveworks – Auto Transmission Extension Housing Seal (Rear Seal) (Part No.S-224205)
Our Top Pick for a 2010 Lexus IS250 Manual Transmission Output Shaft Seal
Invest in a
durable Manual Transmission Output Shaft Seal for your 2010 Lexus, knowing you’re getting trusted brands and expert craftsmanship.
National – Multi-Purpose Seal (Part No.710689)
from
$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
- Resistance to EP lubricants
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
Our Main Shaft Rear Seals for 2010 Lexus IS250s
Make a smart move for your 2010 Lexus IS250 with our Main Shaft Rear Seal for $9.29.
National – Multi-Purpose Seal (Part No.710416)
from
$9.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; single-lip
- Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
- Good low temperature capability
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
FAQs for 2010 Lexus IS250 Transmission Seals
What are the best-selling Transmission Seals for 2010 Lexus IS250s?
Out of 6 Transmission Seals that fit 2010 Lexus IS250s, the following parts are the top sellers:
- Multi Purpose Seal (18442595) – $10.99
- Multi-Purpose Seal (10462153) – $11.99
- Multi-Purpose Seal (18442680) – $7.99
What’s the price range for 2010 Lexus IS250 Transmission Seals?
The prices of Transmission Seals for the 2010 Lexus IS250 range from $4.49 up to $11.99 for the most premium parts.
What is the average price of a Transmission Seal for a 2010 Lexus IS250?
The average price for Transmission Seals for the 2010 Lexus IS250 is $8.54. Keep in mind the variety of part types within our Transmission Seal category, where you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Transmission Seals for other Lexus IS250 model years?
What are the cheapest Transmission Seals for my 2010 Lexus IS250?
The cheapest 2010 Lexus IS250 Transmission Seals we carry are:
- Auto Transmission Extension Housing Seal (Rear Seal) (11494007) – $4.49
- Auto Transmission Manual Shaft Seal (11494069) – $6.49
- Multi-Purpose Seal (18442680) – $7.99
- Multi-Purpose Seal (15440007) – $9.29
- Multi Purpose Seal (18442595) – $10.99
Does Advance Auto Parts sell Transmission Seals for any other 2010 Lexus models?
Yes. We stock Transmission Seals for 11 other popular 2010 Lexus models. Some of the most popular are 2010 ES350 Transmission Seals, 2010 RX350 Transmission Seals, 2010 GX460 Transmission Seals, 2010 SC430 Transmission Seals, and 2010 IS350 Transmission Seals.
What types of Transmission Seals do you sell for my 2010 Lexus IS250?
As of 11/2/25, these are some of the most in-demand types of Transmission Seals for a 2010 Lexus IS250:
Can I get help with 2010 Lexus IS250 Transmission Seal orders?
Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Transmission Seals and more.
What is your return policy for Lexus IS250 Transmission Seals?
Advance Auto Parts keeps returns simple. For new Lexus IS250 Transmission Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.