2008 Lexus IS250 Transmission Seals

Please Select your Vehicle to See Exact Fit Parts

Keep Your 2008 Lexus IS250 in Top Shape with Quality Transmission Seals

Whether you’re repairing or upgrading your Transmission Seal, using high-quality parts is key to keeping your 2008 Lexus IS250 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Automatic Transmission Transfer Shaft Seals, Automatic Transmission Output Shaft Seals, and Transmission Seals and O-rings. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Transmission Seals from Trusted Brands

Looking for a reliable Transmission Seal? We’ve got you covered with options from brands you know and trust like National. For example, National Transmission Seals start at just $17.29 with an average 4.3 star rating. With over 1 reviews and a solid 5.0 star average, you can shop with confidence knowing other Lexus IS250 owners approve.

Explore Related Parts

While you’re upgrading or replacing your Transmission Seal, don’t forget to check out other key components like Automatic Transmission Pan and Gaskets and Transmission Mounts. At Advance Auto Parts, we’re here to help you keep your 2008 Lexus IS250 in peak condition, inside and out.

Essential 2008 Lexus IS250 Transmission Seals

National – National Multi-Purpose Seal, 2025 (Part No.2025)

National Multi-Purpose Seal, 2025

from

$17.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Multi-Purpose Seal, 710416 (Part No.710416)

National Multi-Purpose Seal, 710416

from

$9.39
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Driveworks – Driveworks Auto Transmission Manual Shaft Seal, S-221207 (Part No.S-221207)

Driveworks Auto Transmission Manual Shaft Seal, S-221207

from

$6.49
Driveworks Auto Transmission Manual Shaft Seal, S-221207.
See More

National – National Multi-Purpose Seal, 221207 (Part No.221207)

National Multi-Purpose Seal, 221207

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Multi-Purpose Seal, 224205 (Part No.224205)

National Multi-Purpose Seal, 224205

from

$5.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Multi-Purpose Seal, 710689 (Part No.710689)

National Multi-Purpose Seal, 710689

from

$12.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Driveworks – Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205 (Part No.S-224205)

Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205

from

$4.49
Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205.
See More

Most Popular Automatic Transmission Transfer Shaft Seal for 2008 Lexus IS250s

Enhance your 2008 Lexus IS250 with this popular Automatic Transmission Transfer Shaft Seal we have in stock, for $9.39.

National – National Multi-Purpose Seal, 710416 (Part No.710416)

National Multi-Purpose Seal, 710416

from

$9.39
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Best-Selling 2008 Lexus IS250 Automatic Transmission Output Shaft Seal

Upgrade your IS250 with our best-selling Automatic Transmission Output Shaft Seal.

Driveworks – Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205 (Part No.S-224205)

Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205

from

$4.49
Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205.
See More

Top-Quality Transmission Seals and O-rings for 2008 Lexus IS250s

Choose a high-quality OEM or aftermarket Transmission Seals and O-ring for Lexus IS250s and enjoy top-notch performance from $5.99.

National – National Multi-Purpose Seal, 221207 (Part No.221207)

National Multi-Purpose Seal, 221207

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Multi-Purpose Seal, 710689 (Part No.710689)

National Multi-Purpose Seal, 710689

from

$12.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Multi-Purpose Seal, 224205 (Part No.224205)

National Multi-Purpose Seal, 224205

from

$5.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Our Top Pick for a 2008 Lexus IS250 Shift Shaft Seal

Invest in a durable Shift Shaft Seal for your 2008 Lexus, knowing you’re getting trusted brands and expert craftsmanship.

Driveworks – Driveworks Auto Transmission Manual Shaft Seal, S-221207 (Part No.S-221207)

Driveworks Auto Transmission Manual Shaft Seal, S-221207

from

$6.49
Driveworks Auto Transmission Manual Shaft Seal, S-221207.
See More

Our Top-Rated Automatic Transmission Oil Pump Seals for 2008 Lexus IS250s

Make a smart move for your 2008 Lexus IS250 with our Automatic Transmission Oil Pump Seal for $17.29.

National – National Multi-Purpose Seal, 2025 (Part No.2025)

National Multi-Purpose Seal, 2025

from

$17.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Top-Rated Transmission Seal Brands For Your 2008 Lexus IS250

When it comes to finding the perfect Transmission Seal for your 2008 Lexus IS250, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 2 trusted brands. We carry the most popular Transmission Seal brands including National, and more, all known for their exceptional customer ratings (average brand rating of 4.3 stars) and competitive prices, as low as $17.29. Purchasing a Transmission Seal from us here at Advance Auto Parts is a smart move for both you and your 2008 Lexus IS250, providing peace of mind with parts that meet or exceed OEM standards.

Popular National 2008 Lexus IS250 Transmission Seals

If you’re looking for a top-quality Transmission Seal for your 2008 Lexus IS250, Advance Auto Parts has exactly what you need with our selection of National Transmission Seals. We have 1 National Transmission Seals in stock for this fitment, all known for their durability and precision fit. With prices starting at just $17.29, you’ll find the perfect Transmission Seal for your needs and budget. National Transmission Seals for the 2008 Lexus IS250 come highly rated, with over 1 customer reviews and an impressive average rating of 4.3 stars. Choosing a National Transmission Seal from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
National Multi-Purpose Seal, 2025
from $17.29
(1)
National Multi-Purpose Seal, 2025
“It fit my 1998 Camry front crankshaft O-ring exactly. I can’t say how long it will last, but hopefully as long as the last one.”

FAQs for 2008 Lexus IS250 Transmission Seals

What are the best-selling Transmission Seals for 2008 Lexus IS250s?

Out of 7 Transmission Seals that fit 2008 Lexus IS250s, the following parts are the top sellers:

What’s the price range for 2008 Lexus IS250 Transmission Seals?

The prices of Transmission Seals for the 2008 Lexus IS250 range from $4.49 up to $17.29 for the most premium parts.

What is the average price of a Transmission Seal for a 2008 Lexus IS250?

The average price for Transmission Seals for the 2008 Lexus IS250 is $9.80. Keep in mind the variety of part types within our Transmission Seal category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Transmission Seals for other Lexus IS250 model years?

Yes, we carry Transmission Seals for 8 model years of Lexus IS250s between 2006 and 2015. The following model years are the most popular for Transmission Seal purchases: 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2007, and 2006.

What are the cheapest Transmission Seals for my 2008 Lexus IS250?

The cheapest 2008 Lexus IS250 Transmission Seals we carry are:

Does Advance Auto Parts sell Transmission Seals for any other 2008 Lexus models?

Yes. We stock Transmission Seals for 11 other popular 2008 Lexus models. Some of the most popular are 2008 ES350 Transmission Seals, 2008 RX350 Transmission Seals, 2008 SC430 Transmission Seals, 2008 RX400H Transmission Seals, and 2008 IS350 Transmission Seals.

What are the top-rated Transmission Seals that fit the 2008 Lexus IS250?

The one 2008 Lexus IS250 Transmission Seal we have in stock is the Driveworks Auto Transmission Extension Housing Seal (Rear Seal), S-224205. It costs $4.49.

What types of Transmission Seals do you sell for my 2008 Lexus IS250?

As of 8/2/26, these are some of the most in-demand types of Transmission Seals for a 2008 Lexus IS250:

Can I get help with 2008 Lexus IS250 Transmission Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Transmission Seals and more.

What is your return policy for Lexus IS250 Transmission Seals?

Advance Auto Parts keeps returns simple. For new Lexus IS250 Transmission Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.