2006 GMC Sierra 3500 Engine Cooling Parts

Essential 2006 GMC Sierra 3500 Engine Cooling Parts

Dorman – Coolant Housing/Water Outlet: With Housing and Gasket, 180 Degree Neck Angle (Part No.902-2060)

Coolant Housing/Water Outlet: With Housing and Gasket, 180 Degree Neck Angle

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$26.49
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models.
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking.
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
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Dorman – Ford Trim Panel Retainers (Part No.963-022)

Ford Trim Panel Retainers

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$3.49
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application.
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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GM Genuine Parts – Engine Cooling Fan Clutch (Part No.15-4694)

Engine Cooling Fan Clutch

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$348.99
GM Genuine Parts Engine Cooling Fan Clutches are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These engine cooling fan clutches control the speed of the radiator fan based on the temperature of the air after it passes through the radiator fins. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps quiet noisy cooling fans with stuck fan clutches
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Dorman – Water Pump Outlet Pipe (Part No.626-661)

Water Pump Outlet Pipe

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$82.99
This engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles. It is engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion..

Product Features:
  • Direct replacement – this engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles.
  • Ideal solution – engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
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Imperial – Electric Fan – 14" Diameter (Part No.226114)

Electric Fan - 14" Diameter

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$99.99
Product Features:
  • Motors built and tested to quality specifications
  • 14 in. universal fit reversible fan
  • 1250 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
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Felpro – WATER PUMP MOUNTING GASKET SET (Part No.ES 73010)

WATER PUMP MOUNTING GASKET SET

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$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Motorad – Thermostat Kit: Includes Inlet, Thermostat and Seal, 187 Degrees (Part No.524KT)

Thermostat Kit: Includes Inlet, Thermostat and Seal, 187 Degrees

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$45.49
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Coolant Temperature Sensor (Part No.WTC1261)

Coolant Temperature Sensor

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$28.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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Felpro – Engine Coolant Outlet Gasket (Part No.35757)

Engine Coolant Outlet Gasket

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$7.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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GMB – GMB Water Pump (Part No.G3000395001GMB)

GMB Water Pump

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$184.06
The GMB Water Pump contains no remanufactured components and is designed to combat engine overheating associated with higher RPM, performance and high load applications. All GMB Water Pumps feature a precision ground, heavy duty steel bearing that`s completely sealed and lubricated for life. A specially modified, high performance impeller eliminates cavitation at high RPM`s, maintaining maximum volumetric flow of coolant, thus reducing engine temperature and increasing horsepower.

Product Features:
  • OE-Equivalent and direct fit application.
  • 100% new with no remanufactured parts.
  • High flow design
  • Factory lubricated bearing assembly
  • Precision ground shaft and hub
  • OE quality forged housing for maximum coolant flow
  • Precision built and balanced
  • Pressed on impeller for increased water flow
  • Unique no sealed required gasket
  • Unitized seal protects bearings and provides long life leak free performance.
  • Factory sealed precision ground one piece bearing assembly
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Felpro – Multi-Purpose O-Ring (Part No.35633)

Multi-Purpose O-Ring

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$2.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
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ACDelco – 15-80692 GM Original Equipment Engine Cooling Fan Blade (Part No.G5050374437ACD)

15-80692 GM Original Equipment Engine Cooling Fan Blade

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$139.82
ACDelco GM Original Equipment Engine Cooling Fan Blades are located between the radiator and engine and are GM-recommended replacements for your vehicle’s original components. The fan is a part of the engine cooling system, which moves air across the radiator and A/C condenser to remove heat from the engine cooling system and the AC refrigerant system. The fan may be belt-driven or operated by an electric motor. This cooling fan blade has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Dorman – Engine Heater Hose Assembly (Part No.626-543)

Engine Heater Hose Assembly

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$80.99
This replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models.
  • Restores functionality – reliable replacement for an original part that is leaking, cracked or failed from corrosion and heat.
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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ACDelco – GM Original Equipment Oil Cooler Seal (Part No.A6310320812ACD)

GM Original Equipment Oil Cooler Seal

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$45.26
The ACDelco GM Original Equipment Engine Oil Cooler Seal is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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KAI – Cooling Fan Shroud (Part No.GM3110139)

Cooling Fan Shroud

from

$37.99
New Platinum Pro Lower Fan Shroud, 6.0 Liter V8 Engine

Product Features:
  • 6.0 Liter V8 Engine
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Felpro – Engine Coolant Thermostat Housing Seal (Part No.35720)

Engine Coolant Thermostat Housing Seal

from

$4.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
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Felpro – Engine Water Pump Gasket (Part No.35758)

Engine Water Pump Gasket

from

$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Dorman – Coolant Bypass Tube O-Ring Kit (Part No.926-424)

Coolant Bypass Tube O-Ring Kit

from

$19.29
Product Features:
  • Ideal replacement – this coolant O-ring kit matches the factory O-rings to ensure a complete and reliable repair.
  • Durable construction – made of quality materials for leak-free service.
  • Complete solution – includes all O-rings required to repair or replace specified coolant pipe
  • Quality tested – this part has undergone try-on and material testing to ensure a quality fit and long service life
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Dorman – Chrysler, Ford, GM Mud Shield Retainer (Part No.963-014D)

Chrysler, Ford, GM Mud Shield Retainer

from

$4.49
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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Carquest Premium – Standard Thermostat: With Seal, 195 Degrees (Part No.13899)

Standard Thermostat: With Seal, 195 Degrees

from

$7.29
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Daytime Running Light Resistor Connector (Part No.PTA1113)

Daytime Running Light Resistor Connector

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$29.49
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Carquest Premium – Radiator: With Engine and Transmission Oil Coolers (Part No.432306)

Radiator: With Engine and Transmission Oil Coolers

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$283.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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Dorman – Engine Cooling Fan Pulley Bracket (Part No.300-826)

Engine Cooling Fan Pulley Bracket

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$271.99
This engine cooling fan pulley bracket is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine cooling fan pulley bracket matches the fit and function of the factory part on specified years, makes and models.
  • Ideal solution – this bracket is a reliable replacement for an original part that has failed due to fatigue.
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Pressurized Coolant Reservoir: Clear, Plastic, Original Equipment Replacement (Part No.603-125)

Pressurized Coolant Reservoir: Clear, Plastic, Original Equipment Replacement

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$93.99
This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part.

Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part.
  • Ideal solution – engineered for a seamless installation.
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1007)

Water Pump with Fan Clutch

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$158.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
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Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-106)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

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$116.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade.
  • Quality construction – manufactured from premium materials for a long service life.
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Permatex – Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ (Part No.22071)

Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ

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$6.99
Permatex Water Pump & Thermostat RTV Silicone Gasket Maker is a noncorrosive, sensor-safe RTV silicone gasket material formulated for water pumps and thermostat housings. Permatex Water Pump & Thermostat has the highest water-glycol resistance available in an RTV silicone.

Product Features:
  • Sensor-safe, noncorrosive RTV silicone gasket material
  • Formulated specifically for water pumps and thermostat housings
  • Highest water-glycol resistance available in RTV silicone
  • Superior adhesion and flexibility
  • Can be used as a gasket maker or dressing
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2006 GMC Sierra 3500 Engine Cooling Parts

Maybe you’re in the middle of a full rebuild of that 2006 GMC Sierra 3500. Maybe you just need a couple of Engine Cooling Parts. Either way, Advance Auto Parts has 129 different Engine Cooling Parts in our inventory ranging from $2.29 to $655.05. That means you can find the exact parts or products you need to keep that 2006 GMC Sierra 3500 running smoothly.

Engine Cooling Parts are only as good as their brand. We stock 22 different brands to make sure you have plenty of trusted parts to choose from for your 2006 GMC Sierra 3500. Carquest Premium, Permatex, and FELPRO are just some of the brands we stock. Search for brands you know or compare prices and reviews to help you decide!

We know you’ll find the perfect Engine Cooling Parts for your 2006 GMC Sierra 3500, but don’t take our word for it – read our customer ratings and reviews and buy with confidence. Out of the 14,204 reviews in this category, some of the top rated parts include Engine Water Pump Gasket with 4.7 stars and Radiator: With Transmission Oil Cooler with 4.5 stars.

So if you’re in the market for aftermarket Engine Cooling Parts to keep your 2006 GMC Sierra 3500 rolling for years to come, look no further. Shop online and have your products shipped direct to your door, or pick up at the nearest Advance Auto Parts location today!

Engine Cooling Parts Brands To Make Your 2006 GMC Sierra 3500 Last

Simple repair, complete replacement, or a full rebuild. No matter the job, your 2006 GMC Sierra 3500 demands trusted brand parts and products to keep it running. Many trusted brands of Engine Cooling Parts make up Advance Auto Parts’ inventory, and all are ready to help make your Sierra 3500 the best it can be. Be sure to browse some of our top Engine Cooling Parts brands and parts.

Popular ACDelco Engine Cooling Parts

We carry ACDelco parts in our stock across Coolant Temperature Sensors categories, plus more. For a 2006 GMC Sierra 3500, our most popular ACDelco Engine Cooling Parts include:
Engine Coolant Temperature Sensor
from $34.99
(1)
Engine Coolant Temperature Sensor
Coolant Temperature Sensors
Engine Coolant Temperature Sensor
from $42.99
(3)
Engine Coolant Temperature Sensor
Coolant Temperature Sensors

FAQs for 2006 GMC Sierra 3500 Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the 2006 GMC Sierra 3500?

Out of 129 Engine Cooling Parts for the 2006 GMC Sierra 3500, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Water Pump Housing Gaskets
Engine Water Pump
from $101.99
(345)
Engine Water Pump
Water Pumps
Standard Thermostat: With Seal, 195 Degrees
from $7.29
(105)
Standard Thermostat: With Seal, 195 Degrees
Thermostats

What are the top-rated 2006 GMC Sierra 3500 Engine Cooling Parts?

Top-rated Engine Cooling Parts for your 2006 GMC Sierra 3500 based on customer reviews/ratings are:
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
“Great product …easy to use”
Radiator: With Transmission Oil Cooler
from $219.99
(88)
Radiator: With Transmission Oil Cooler
“Perfect fit”
Radiator: With Engine and Transmission Oil Coolers
from $283.99
(73)
Radiator: With Engine and Transmission Oil Coolers
“Price is good and it fits”