2006 GMC Sierra 2500 HD Cooling and Climate Controls

Essential 2006 GMC Sierra 2500 HD Cooling and Climate Controls

Carquest Premium – A/C Discharge Line Hose Assembly (Part No.T66001)

A/C Discharge Line Hose Assembly

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$42.99
Carquest Hose Assemblies are designed to carry refrigerant in an air conditioning system. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • 100% of hose assemblies use Goodyear hoses that meet original equipment specifications for wall thickness and permeation.
  • Tubes and mufflers are designed to meet original equipment specifications for wall thickness.
  • Fittings are designed to couple and seal to eliminate leaks. Trivalent plating is used on steel fittings to enhance corrosion resistance. The fittings conform to original equipment specifications to allow for the proper fit with related air conditioning
  • Welds and crimps meet and exceed original equipment tension specifications.
  • Manufactured to allow flexibility in the hose to conform to engine compartments.
  • O-Rings necessary for installation are included.
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Imperial – High Performance Radiator Fan Motor (Part No.3855)

High Performance Radiator Fan Motor

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$247.99
Motors built And tested to OE specifications; OE fit And design; Out of box installation; Quality construction And assembly
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Dorman – Engine Heater Hose Assembly (Part No.626-591)

Engine Heater Hose Assembly

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$89.99
This replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models
  • Restores functionality – reliable replacement for an original part that is leaking, cracked or failed from corrosion and heat
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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ACDelco – GM Original Equipment Engine Coolant Thermostat (Part No.G4000310418ACD)

GM Original Equipment Engine Coolant Thermostat

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$62.94
An ACDelco GM Original Equipment Engine Coolant Thermostat is a temperature controlled valve located in the engine coolant outlet to, or the inlet from, the radiator, and is a GM-recommended replacement for your vehicle’s original component. It controls the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature. This original equipment engine coolant thermostat has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Control the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – A/C Pressure Switch (Part No.R1054300886ACD)

A/C Pressure Switch

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$67.44
A/C Pressure Switch

ACDelco – Instrument Panel Air Duct Air Temperature Sensor (Part No.15-5632)

Instrument Panel Air Duct Air Temperature Sensor

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$9.99
ACDelco GM Original Equipment HVAC Temperature Sensor is a GM-recommended replacement component for one or more of the following vehicle systems: hvac. This original equipment sensor will provide the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Dorman – HVAC Control Module (Part No.R2059699510DOR)

HVAC Control Module

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$164.53
HVAC Control Module

ACDelco – A/C Temp. Switch (Part No.R1055307459ACD)

A/C Temp. Switch

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$10.70
A/C Temp. Switch

Felpro – Engine Water Pump Gasket (Part No.35664)

Engine Water Pump Gasket

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$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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KAI – A/C Evaporator Core (Part No.EVA010594)

A/C Evaporator Core

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$134.99
New Standard Replacement A/C Evaporator Core, Front, Without Center Console

Product Features:
  • Front, Without Center Console, Made Of Aluminum delete
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest – HVAC Blower Motor Resistor (Part No.RU1064)

HVAC Blower Motor Resistor

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$30.49
BWD is an aftermarket leader, providing a premium line of engine management products. BWD manufactures and distributes high technology critical components for late model domestic and import vehicles. BWD is constantly evolving to give customers the competitive edge they need to compete in today’s ever-changing marketplace.

Product Features:
  • All units are 100% tested using automated equipment that activates the switch, checks for leaks & stresses the part to ensure specification compliance, even under the most demanding operating conditions.
  • Robust design and high grade materials meet the stringent demands of today’s service professional
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Dorman – Coolant Housing/Water Outlet: With Housing, 30 Degree Neck Angle (Part No.902-836)

Coolant Housing/Water Outlet: With Housing, 30 Degree Neck Angle

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$35.49
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
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GM Genuine Parts – Air Conditioning Compressor and Clutch Assembly (Part No.15-20940)

Air Conditioning Compressor and Clutch Assembly

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$577.99
GM Genuine Parts A/C Compressors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These compressors pump refrigerant through the system. The compressor is typically engine driven via the accessory belt, and a clutch on the compressor is used to engage and disengage the compressor. Hybrid vehicles are typically equipped with an electric motor driven compressor. The compressor is lubricated by refrigerant oil. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE). Product contains Decabromodiphenyl ether (decaBDE): Not for sale in Washington D.C.

Product Features:
  • Visual and leak-tested to help ensure the component’s quality and durability
  • The oil separator is part of the compressor and removes oil from the refrigerant to help keep system efficiency
  • GM meets an aggressive engineering requirement for compressor clutch durability and corrosion resistance. Together, these help ensure long-term quality and durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1045)

Water Pump with Fan Clutch

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$162.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
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Factory Air – O-Ring & Gasket A/C System Seal Kit (Part No.26824)

O-Ring & Gasket A/C System Seal Kit

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$19.49
High quality OE replacement part with all components needed to complete the job

Product Features:
  • All the seals needed to complete the job
  • Compatible with both R134a and R12 refrigerants
  • Application specific
  • SUV and rear air applications
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ACDelco – Heating and Air Conditioning Panel Mode Door Actuator (Part No.15-73952)

Heating and Air Conditioning Panel Mode Door Actuator

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$77.99
ACDelco GM Original Equipment HVAC Mode Door Actuators are electric motors attached to the HVAC housing that move or actuate the mode doors or flaps, directing the airflow to the desired outlet vents. These original equipment HVAC mode door actuators are GM-recommended replacements for your vehicle’s original components and have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Corrects mode door malfunction caused by a failed actuator
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Felpro – Engine Water Pump Installation Kit (Part No.ES 71347)

Engine Water Pump Installation Kit

from

$31.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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KAI – A/C Condenser (Part No.CNDDPI3026)

A/C Condenser

from

$114.99
New Platinum Pro A/C Condenser, With Rear Air, With Ambulance Package

Product Features:
  • With Rear Air, With Ambulance Package, Made Of Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Dorman – HVAC Air Door Actuator (Part No.R2046409368DOR)

HVAC Air Door Actuator

from

$114.85
Dorman-engineered with robust materials to improve durability and performance, our HVAC Heater Blend Door Actuators restore and maintain proper functioning of the HVAC Heater Blend Door. Depending on the make and model of your vehicle, the same exact actuator could be suitable for any and all climate control blend door applications – consult Dorman’s website for specific information.

Product Features:
  • Direct replacement for a proper fit every time
  • Recommended for replacement during blend door replacement
  • High quality plastic housing and motor/circuit board included
  • Dorman’s quality testing ensures year after year of trouble-free service
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GM Genuine Parts – Heating and Air Conditioning Blower Control Module (Part No.15-81773)

Heating and Air Conditioning Blower Control Module

from

$72.99
GM Genuine Parts HVAC Blower Motor Control Modules are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These modules are microprocessor computers that modulate HVAC blower motor speed. The blower motor control module receives input from the HVAC control module. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Designed and tested to help ensure quality and durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Imperial – Electric Fan – 14" Diameter (Part No.226114)

Electric Fan - 14" Diameter

from

$99.99
Product Features:
  • Motors built and tested to quality specifications
  • 14 in. universal fit reversible fan
  • 1250 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
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Carquest Premium – Standard Rotation Blower Motor Wheel (Part No.35534)

Standard Rotation Blower Motor Wheel

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$24.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Durable Plastic Material
  • Meets all requirements of international standard ISO 140
  • Suitable for a wide variety of applications
  • Retainer clip installation
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Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.813244)

Radiator: With Transmission Oil Cooler

from

$373.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle’s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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ACDelco – GM Original Equipment Expansion Tank Cap (Part No.G1040206092ACD)

GM Original Equipment Expansion Tank Cap

from

$25.37
An ACDelco GM Original Equipment Expansion Tank Cap is a spring loaded cap that seals the radiator filler neck or surge tank, and is a GM-recommended replacement for your vehicle’s original component. It maintains pressure on the cooling system while the engine is operating, which raises the boiling point of the engine coolant. It also replenishes the system with coolant from the expansion tank (if equipped) when the engine cools off. This original equipment radiator cap has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors. Get the GM quality you know and trust with ACDelco GM Original Equipment Thermostats and Caps. Stay with the brand of parts your General Motors vehicle came with and get peace of mind that the fit, form, and function is up to the high standards and specifications of General Motors. ACDelco GM Original Equipment Thermostats and Caps are engineered for virtually every model of GM car, light duty truck, and sport utility vehicle.

Product Features:
  • Seal and maintain pressure on the cooling system for vehicle safety
  • Raise the boiling point of the engine coolant to maintain efficiency
  • Fit most models of GM vehicles for expanded coverage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Driveworks Water Pumps – Water Pump (Part No.58-566)

Water Pump

from

$83.99
Using advanced re-engineering materials and processes, our remanufactured water pumps match O.E. fit and performance. Each unit is supplied with new, unitized seals and the proper O.E.-specified bearing design to meet the specific radial and axial load re

Product Features:
  • 100% leak testing and hub-pull testing ensures reliable performance.
  • O.E.-supplied NEW unitized seals ensure long-lasting, trouble-free performance.
  • The proper O.E. specified bearing design is installed to meet the specific radial and axial load requirements of each application. This ensures longer bearing life and reliable performance.
  • Thermostat seal and mounting gasket are supplied for ease of installation (where applicable).
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ACDelco – GM Original Equipment Engine Cooling Fan Clutch (Part No.G5010358957ACD)

GM Original Equipment Engine Cooling Fan Clutch

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$506.23
ACDelco GM Original Equipment Engine Cooling Fan Clutches control the speed of the radiator fan based on the temperature of the air after it passes through the radiator fins. This original equipment engine cooling fan clutch is a GM-recommended replacement for your vehicle’s original components and has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Quiets noisy cooling fans with stuck fan clutches, restores fuel economy
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – GM OE A/C Compressor Clutch Kit with Clutch, Coil, and Pulley (Part No.R1010511135ACD)

GM OE A/C Compressor Clutch Kit with Clutch, Coil, and Pulley

from

$353.92
ACDelco GM Original Equipment A/C Compressor Clutch Kits include the compressor clutch, which engages and disengages the compressor when the A/C is switched ON and Off, and other related components. The compressor clutch consists of a pulley, pressure plate, and electromagnetic coil. This original equipment A/C compressor clutch kit is a GM-recommended replacement for you vehicle’s original components and has been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Restore A/C compressor clutch to like new performance
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest Premium – A/C Pressure Transducer Connector (Part No.PTA1151)

A/C Pressure Transducer Connector

from

$25.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Popular 2006 GMC Sierra 2500 HD Cooling and Climate Controls Categories

2006 GMC Sierra 2500 HD Cooling and Climate Controls

You count on your 2006 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 272 Cooling and Climate Controls ranging in price from $1.29 to $577.99, you’re sure to find everything you need for your 2006 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 26 different brands like Carquest Premium, Permatex, and Felpro. 2006 GMC Sierra 2500 HD Cooling and Climate Controls start as low as $1.29!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 25,320 extensive product reviews on 2006 GMC Sierra 2500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Standard Thermostat: With Seal, 195 Degrees with 4.6 stars and Engine Water Pump Gasket with 4.7 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2006 GMC Sierra 2500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2006 GMC Sierra 2500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2006 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like Carquest Premium, Permatex, Felpro, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Blend Doors and Air Conditioning Parts. All are waiting to get your 2006 GMC Sierra 2500 HD back on the road. Some of the top-rated ACDelco products in these categories are:
HVAC Blend Door Actuator: 1 Piece
from $251.99
(1)
HVAC Blend Door Actuator: 1 Piece
Air Blend Door Actuators
Multi-Purpose Pigtail
from $37.99
(2)
Multi-Purpose Pigtail
AC Clutch Coil Connectors
Heating and Air Conditioning Panel Mode Door Actuator
from $77.99
(1)
Heating and Air Conditioning Panel Mode Door Actuator
Heater Blend Doors

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2006 GMC Sierra 2500 HD, and some of our most reviewed Carquest Premium parts include:
Engine Water Pump: New, Gasket/Seals Included
from $153.99
(371)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps
Standard Thermostat: With Seal, 187 Degrees
from $18.79
(189)
Standard Thermostat: With Seal, 187 Degrees
Thermostats

FAQs for 2006 GMC Sierra 2500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2006 GMC Sierra 2500 HD?

Out of 272 Cooling and Climate Controls for the 2006 GMC Sierra 2500 HD, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets
Engine Water Pump
from $101.99
(345)
Engine Water Pump
Water Pumps
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
from $11.49
(95)
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
Water Pump Housing Gaskets

What are the top-rated 2006 GMC Sierra 2500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2006 GMC Sierra 2500 HD based on customer reviews/ratings are:
Standard Thermostat: With Seal, 195 Degrees
from $7.29
(105)
Standard Thermostat: With Seal, 195 Degrees
“Replaced my old one.. No problems”
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
“Great product …easy to use”
A/C Dark Grey Porous Orifice Tube
from $15.99
(97)
A/C Dark Grey Porous Orifice Tube
“Picture says it all – the 12-yr old tube was pretty filthy and not reusable. If you’re working on your A/C, this is a good item to replace while you'”