2006 Ford E-250 Econoline Engine Cooling Parts

Keep Your 2006 Ford E-250 Econoline in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2006 Ford E-250 Econoline looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Radiators, Thermostat and Water Outlet Assemblies, and Water Pumps. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium, FELPRO, and Dorman. For example, Carquest Premium Engine Cooling Parts start at just $14.99 with an average 4.4 star rating. FELPRO and Dorman offer similar pricing and quality, backed by strong customer feedback. With over 952 reviews and a solid 4 star average, you can shop with confidence knowing other Ford E-250 Econoline owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2006 Ford E-250 Econoline Engine Cooling Part at Advance Auto Parts is around $53.17, with a range that starts at $2.99 and goes up to $416.99. With 42 options in stock from 11 trusted brands, finding the right fit is easy. Popular picks like Multi-Purpose O-Ring, High Flow Thermostat: 170 Degrees, and UltraStat Thermostat: 195 Degrees start at just $10.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Blower Motor and Related Products and HVAC Electrical Parts. At Advance Auto Parts, we’re here to help you keep your 2006 Ford E-250 Econoline in peak condition, inside and out.

Essential 2006 Ford E-250 Econoline Engine Cooling Parts

Felpro – Engine Water Pump Bypass Pipe O-Ring Kit (Part No.ES 73048)

Engine Water Pump Bypass Pipe O-Ring Kit

from

$7.99
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Unsurpassed quality you can trust
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Motorcraft – THERMOSTAT O-RING (Part No.RG-571)

THERMOSTAT O-RING

from

$2.99
THERMOSTAT O-RING

Edelbrock – Waterneck for Small Block Ford (Part No.48143)

Waterneck for Small Block Ford

from

$25.49
Edelbrock part No. 48143 Waterneck is designed for use with small-block Ford V8 engine applications. This Black water neck is a great way to finish off your engine. It features a 15 deg. neck and O-ring design for an improved seal, which also allows for removal without requiring a new gasket. Fits any 1-1/2″ diameter outlet hose.
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Imperial – Electric Fan, 12" Diameter (Part No.226112)

Electric Fan, 12" Diameter

from

$108.99
Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Imperial.

Product Features:
  • Rapid-Cool Thin-Line electric fans
  • 12″ Diameter
  • 800 CFM
  • Use as a pusher or puller fan
  • Motors built and tested to quality specifications
  • 12 in. universal fit reversible fan
  • 800 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
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Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees (Part No.5002KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees

from

$35.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


    Product Features:
    • High grade stainless steel and copper construction
    • Meets or exceeds OEM standards
    • Consistent and precise response to cooling system needs
    • Original equipment design for worry-free direct fit replacement
    • 100% tested and calibrated
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Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54208)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$16.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
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Carquest Premium – Universal Fan Clutch – Severe Duty (Part No.215052)

Universal Fan Clutch - Severe Duty

from

$60.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
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Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.432338)

Radiator: With Transmission Oil Cooler

from

$316.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
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Felpro – WATER OUTLET GASKET (Part No.35355)

WATER OUTLET GASKET

from

$2.99
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Dorman – Help – Drain Cock-Brass-Screw In Style-3/8 In. NPT (Part No.61102)

Drain Cock-Brass-Screw In Style-3/8 In. NPT

from

$9.99
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.

Product Features:
  • Direct replacement – this radiator drain petcock matches the fit and function of the original equipment part
  • Durable construction – this part is made of quality materials for a long service life
  • Saves money – offers original equipment quality at a competitive price
  • Quality assured – this petcock has undergone virtual testing to assure proper fit and function
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Carquest Premium – Radiator Cap Tester Adapter (Part No.12552)

Radiator Cap Tester Adapter

from

$14.99
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive coolant caps.

Product Features:
  • Machined metal construction
  • Works with MT-300 pressure tester
  • Tests coolant caps
  • Professional quality
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Imperial – Adjustable Thermostatic Fan Control (Part No.226203)

Adjustable Thermostatic Fan Control

from

$23.99
Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Imperial.

Product Features:
  • Economy adjustable thermostatic fan control
  • Economy Model; 32-248 Deg. F
  • For use with Imperial electric fans
  • Probe installs into radiator fins
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Brass construction for accurate temperature sensing
  • Zinc coated terminal to resist corrosion
  • Vehicle specific applications
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Carquest Premium – Engine Coolant Temperature Sensor (Part No.ACA1523)

Engine Coolant Temperature Sensor

from

$29.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Mr. Gasket – Thermocap Radiator Cap (Part No.2471S)

Thermocap Radiator Cap

from

$51.99
Knowing your coolant temperature can help to prevent burn injuries. Thermocap Cap, with its built-in calibrated thermometer, indicates the coolant temperature. This is useful information prior to cap removal. Never attempt to remove Thermocap Cap when the coolant temperature is very hot. The escaping hot coolant and steam may burn you. Reclamation valve works great with your coolant recovery system. Your radiator can reclaim coolant from your overflow bottle. Wide 30 degree to 270 degree F temperature range. Calibrated in centigrade and Fahrenheit. Color-coded temperature ranges.

Product Features:
  • Indicates Coolant Temperature
  • Helps to Prevent Injuries from coolant or steam burns
  • Integrated Coolant Reclamation Valve
  • Improves Underhood Appearance
  • Fahrenheit and centigrade readings
  • Various valve pressures available
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Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3079)

Engine Water Pump: New, Gasket/Seals Included

from

$101.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
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Carquest Premium – Hazard Warning Flasher (Part No.FCA1011)

Hazard Warning Flasher

from

$35.99
The hazard warning flasher is a type of circuit breaker in the turn signal system that provides the ‘blink’, or flashing mechanism in the hazard lighting system.

Product Features:
  • Application matched component to ensure the system can be returned to like new condition.
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
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Carquest Premium – Standard Thermostat: 180 Degrees (Part No.13358)

Standard Thermostat: 180 Degrees

from

$10.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Coolant Housing/Water Outlet: Gasket Included (Part No.84847)

Coolant Housing/Water Outlet: Gasket Included

from

$21.79
We are proud to offer this Carquest product line: Carquest Water Outlets. Our products are engineered and tested to provide years of trouble free operation and designed to be hassle free OE replacement part that meets and/or exceeds OE standards. Backed by over 50 years of mobile temperature control experience, fix it once and fix it right with CARQUST Water Outlets and Thermostat Housings.

Product Features:
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable))
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • Direct-fit replacement for ease of installation
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable)
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • Direct-fit replacement for ease of installation
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US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1020)

Water Pump with Fan Clutch

from

$109.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
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US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1026)

Water Pump with Fan Clutch

from

$88.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
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Dorman – Pressurized Coolant Reservoir: White, Plastic, Original Equipment Replacement (Part No.603-029)

Pressurized Coolant Reservoir: White, Plastic, Original Equipment Replacement

from

$105.99
Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part
  • Ideal solution – engineered for a seamless installation
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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Felpro – Engine Water Pump Gasket (Part No.35478)

Engine Water Pump Gasket

from

$7.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Edelbrock – Engine Water Pump Gasket Set for Ford 289-302 (Part No.7253)

Engine Water Pump Gasket Set for Ford 289-302

from

$23.99
Edelbrock #7253 Engine Water Pump Gasket Set Ford 289-302. Is it time to rebuild your Edelbrock mechanical water pump? No problem– these Edelbrock water pump gaskets will keep your water pump leak-free. They are manufactured from quality materials and ca

Product Features:
  • Composite Material
  • 1-Back Plate To Timing Cover
  • 1-Water Pump To Timing Cover
  • 2-Back Plate To Water Pump
  • For Early SB Ford
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Carquest Premium – Multi-Purpose Relay (Part No.RAA1751)

Multi-Purpose Relay

from

$22.99
Relays are electrical switches used to convert a small electrical load into a circuit capable of handling a high amperage load. Computers and small switches are not designed to carry the higher amperage requirement of a circuit that may have an electric motor, solenoid, or high amperage lighting fixture. Within a relay are contacts that are controlled with electromagnetism, when the circuit switch commands the device on or off, magnetism will pull or release the contact arm closing or opening the contacts within the relay that carry the voltage.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
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Dorman – Clutch Fan Blade: Plastic, Cost Effective and Reliable (Part No.620-163)

Clutch Fan Blade: Plastic, Cost Effective and Reliable

from

$96.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Most Popular Radiators for 2006 Ford E-250 Econolines

Enhance your 2006 Ford E-250 Econoline with one of the 3 Radiators we have in stock, starting at just $303.99.

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.431359)

Radiator: With Transmission Oil Cooler

from

$311.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.431360)

Radiator: With Transmission Oil Cooler

from

$303.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.434080)

Radiator: With Transmission Oil Cooler

from

$416.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
See More

Best-Selling 2006 Ford E-250 Econoline Thermostat and Water Outlet Assembly

Upgrade your E-250 Econoline with our best-selling Thermostat and Water Outlet Assembly.

Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees (Part No.5002KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 194 Degrees

from

$35.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Top-Quality Water Pumps for 2006 Ford E-250 Econolines

Choose a high-quality OEM or aftermarket Water Pump for Ford E-250 Econolines and enjoy top-notch performance from $56.99.

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T4196)

Engine Water Pump: New, Gasket/Seals Included

from

$56.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
See More

Motorcraft – ENGINE WATER PUMP (Part No.PW-423)

ENGINE WATER PUMP

from

$124.99
ENGINE WATER PUMP

Top Picks for 2006 Ford E-250 Econoline Thermostats

Invest in one of our 7 durable Thermostats for your 2006 Ford, knowing you’re getting trusted brands and expert craftsmanship.

Carquest Premium – High Flow Thermostat: 170 Degrees (Part No.13967)

High Flow Thermostat: 170 Degrees

from

$14.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • Larger opening for increased coolant flow
  • Increased strength and durability
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: 180 Degrees (Part No.13778)

Standard Thermostat: 180 Degrees

from

$15.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad UltraStats – UltraStat Thermostat: 180 Degrees (Part No.5228-180JV)

UltraStat Thermostat: 180 Degrees

from

$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
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Carquest Premium – High Flow Thermostat: 180 Degrees (Part No.13968)

High Flow Thermostat: 180 Degrees

from

$12.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • Larger opening for increased coolant flow
  • Increased strength and durability
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: 195 Degrees (Part No.14989)

Standard Thermostat: 195 Degrees

from

$16.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium Stats – High Flow Thermostat: 180 Degrees (Part No.45778)

High Flow Thermostat: 180 Degrees

from

$15.79
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad UltraStats – UltraStat Thermostat: 195 Degrees (Part No.5228-195JV)

UltraStat Thermostat: 195 Degrees

from

$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
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Our Top-Rated Thermostat and Water Outlet Gaskets for 2006 Ford E-250 Econolines

Make a smart move for your 2006 Ford E-250 Econoline with our Thermostat and Water Outlet Gasket for $10.99.

Felpro – Multi-Purpose O-Ring (Part No.35489)

Multi-Purpose O-Ring

from

$10.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Top-Rated Engine Cooling Part Brands For Your 2006 Ford E-250 Econoline

When it comes to finding the perfect Engine Cooling Part for your 2006 Ford E-250 Econoline, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 11 trusted brands. We carry the most popular Engine Cooling Part brands including FELPRO, Carquest Premium, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $7.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2006 Ford E-250 Econoline, providing peace of mind with parts that meet or exceed OEM standards.

Popular FELPRO 2006 Ford E-250 Econoline Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2006 Ford E-250 Econoline, Advance Auto Parts has exactly what you need with our selection of FELPRO Engine Cooling Parts. We have 3 FELPRO Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $7.99 and an average cost of $8.99, you’ll find the perfect Engine Cooling Part for your needs and budget. FELPRO Engine Cooling Parts for the 2006 Ford E-250 Econoline come highly rated, with over 122 customer reviews and an impressive average rating of 4.6 stars. Choosing a FELPRO Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Engine Water Pump Gasket
from $7.99
(11)
Engine Water Pump Gasket
“Perfect fit !”
Engine Water Pump Bypass Pipe O-Ring Kit
from $7.99
(1)
Engine Water Pump Bypass Pipe O-Ring Kit
“It was just what I needed”
Multi-Purpose O-Ring
from $10.99
(110)
Multi-Purpose O-Ring
“It work and price was reasonable”

Top-Quality Carquest Premium 2006 Ford E-250 Econoline Engine Cooling Parts

For those in search of a high-quality Engine Cooling Part for their 2006 Ford E-250 Econoline, Advance Auto Parts offers a great selection of Carquest Premium Engine Cooling Parts. With 3 Carquest Premium Engine Cooling Parts in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Engine Cooling Parts start at just $14.99, with an average price of $114.32, giving you a range of options to suit your budget. Backed by over 46 customer ratings and an average rating of 4.4 stars, Carquest Premium Engine Cooling Parts provide both reliability and excellent performance. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
Radiator: With Transmission Oil Cooler
from $311.99
(14)
Radiator: With Transmission Oil Cooler
“Exact fit”
Standard Thermostat: 180 Degrees
from $15.99
(16)
Standard Thermostat: 180 Degrees
“Car did not run hot, but lower radiator hose started leaking and was too hot to touch. Replaced and lower radiator hose temp was much cooler. Car runs”
High Flow Thermostat: 170 Degrees
from $14.99
(16)
High Flow Thermostat: 170 Degrees
“Great fit . Works properly so far so good”

FAQs for 2006 Ford E-250 Econoline Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2006 Ford E-250 Econolines?

Out of 42 Engine Cooling Parts that fit 2006 Ford E-250 Econolines, the following parts are the top sellers:

What’s the price range for 2006 Ford E-250 Econoline Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2006 Ford E-250 Econoline range from $2.99 up to $416.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2006 Ford E-250 Econoline?

The average price for Engine Cooling Parts for the 2006 Ford E-250 Econoline is $53.17. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Ford E-250 Econoline model years?

Yes, we carry Engine Cooling Parts for 30 model years of Ford E-250 Econolines between 1975 and 2005. The following model years are the most popular for Engine Cooling Part purchases: 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, and 1997.

What are the cheapest Engine Cooling Parts for my 2006 Ford E-250 Econoline?

The cheapest 2006 Ford E-250 Econoline Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2006 Ford models?

What are the top-rated Engine Cooling Parts that fit the 2006 Ford E-250 Econoline?

The one 2006 Ford E-250 Econoline Engine Cooling Part we have in stock is the THERMOSTAT O-RING. It costs $2.99.

What types of Engine Cooling Parts do you sell for my 2006 Ford E-250 Econoline?

As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2006 Ford E-250 Econoline:

Can I get help with 2006 Ford E-250 Econoline Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Engine Cooling Parts and more.

What is your return policy for Ford E-250 Econoline Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Ford E-250 Econoline Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.