2001 Lexus RX300 Transmission Seals

Keep Your 2001 Lexus RX300 in Top Shape with Quality Transmission Seals

Whether you’re repairing or upgrading your Transmission Seal, using high-quality parts is key to keeping your 2001 Lexus RX300 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Automatic Transmission Output Shaft Seals, Shaft Seals, and Manual Transmission Output Shaft Seals. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2001 Lexus RX300 Transmission Seal at Advance Auto Parts is around $10.05, with a range that starts at $3.49 and goes up to $15.99. With 12 options in stock from 4 trusted brands, finding the right fit is easy. Popular picks like Multi-Purpose Seal, Multi Purpose Seal, and Multi Purpose Seal start at just $8.79 and offer a great balance of form and function.

Essential 2001 Lexus RX300 Transmission Seals

National – Multi-Purpose Seal (Part No.710319)

Multi-Purpose Seal

from

$9.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Manual Transmission Output Shaft Seal (Part No.S-710319)

Manual Transmission Output Shaft Seal

from

$3.49
Product Features:
  • Brand may vary by location
See More

National – Multi-Purpose Seal (Part No.710419)

Multi-Purpose Seal

from

$8.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)

Auto Transmission Manual Shaft Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

National – Automatic Transmission Output Shaft Seal (Part No.710955)

Automatic Transmission Output Shaft Seal

from

$12.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

FAG US – Shaft Seal (Part No.SS4892)

Shaft Seal

from

$10.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

National – Automatic Transmission Output Shaft Seal (Part No.710876)

Automatic Transmission Output Shaft Seal

from

$8.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.224020)

Multi Purpose Seal

from

$8.79
Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi-Purpose Seal (Part No.712551)

Multi-Purpose Seal

from

$15.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.221207)

Multi Purpose Seal

from

$10.99
Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

ATP – AT SEAL DRIVE AXLE (Part No.RO-79)

AT SEAL DRIVE AXLE

from

$14.49
AT SEAL DRIVE AXLE

National – Multi-Purpose Seal (Part No.710416)

Multi-Purpose Seal

from

$9.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Most Popular Automatic Transmission Output Shaft Seals for 2001 Lexus RX300s

Enhance your 2001 Lexus RX300 with one of the 3 Automatic Transmission Output Shaft Seals we have in stock, starting at just $8.99.

National – Automatic Transmission Output Shaft Seal (Part No.710876)

Automatic Transmission Output Shaft Seal

from

$8.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Automatic Transmission Output Shaft Seal (Part No.710955)

Automatic Transmission Output Shaft Seal

from

$12.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

FAG US – Shaft Seal (Part No.SS4892)

Shaft Seal

from

$10.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

Best-Selling 2001 Lexus RX300 Shaft Seal

Upgrade your RX300 with our best-selling Shaft Seal.

Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)

Auto Transmission Manual Shaft Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

Top-Quality Manual Transmission Output Shaft Seals for 2001 Lexus RX300s

Choose a high-quality OEM or aftermarket Manual Transmission Output Shaft Seal for Lexus RX300s and enjoy top-notch performance from $3.49.

National – Multi-Purpose Seal (Part No.710419)

Multi-Purpose Seal

from

$8.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Manual Transmission Output Shaft Seal (Part No.S-710319)

Manual Transmission Output Shaft Seal

from

$3.49
Product Features:
  • Brand may vary by location
See More

Our Top Pick for a 2001 Lexus RX300 Extension Housing Seal

Invest in a durable Extension Housing Seal for your 2001 Lexus, knowing you’re getting trusted brands and expert craftsmanship.

National – Multi-Purpose Seal (Part No.710319)

Multi-Purpose Seal

from

$9.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Top-Rated Transmission Seals and O-rings for 2001 Lexus RX300s

Make a smart move for your 2001 Lexus RX300 with products all priced from $8.79 to $15.99.

National – Multi-Purpose Seal (Part No.712551)

Multi-Purpose Seal

from

$15.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.224020)

Multi Purpose Seal

from

$8.79
Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

FAQs for 2001 Lexus RX300 Transmission Seals

What are the best-selling Transmission Seals for 2001 Lexus RX300s?

Out of 12 Transmission Seals that fit 2001 Lexus RX300s, the following parts are the top sellers:

What’s the price range for 2001 Lexus RX300 Transmission Seals?

The prices of Transmission Seals for the 2001 Lexus RX300 range from $3.49 up to $15.99 for the most premium parts.

What is the average price of a Transmission Seal for a 2001 Lexus RX300?

The average price for Transmission Seals for the 2001 Lexus RX300 is $10.05. Keep in mind the variety of part types within our Transmission Seal category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Transmission Seals for other Lexus RX300 model years?

Yes, we carry Transmission Seals for 3 model years of Lexus RX300s between 1999 and 2003. The following model years are the most popular for Transmission Seal purchases: 2003, 2002, 2000, and 1999.

What are the cheapest Transmission Seals for my 2001 Lexus RX300?

The cheapest 2001 Lexus RX300 Transmission Seals we carry are:

Does Advance Auto Parts sell Transmission Seals for any other 2001 Lexus models?

Yes. We stock Transmission Seals for 5 other popular 2001 Lexus models. Some of the most popular are 2001 ES300 Transmission Seals, 2001 GS300 Transmission Seals, 2001 LS430 Transmission Seals, 2001 LX470 Transmission Seals, and 2001 IS300 Transmission Seals.

What are the top-rated Transmission Seals that fit the 2001 Lexus RX300?

The one 2001 Lexus RX300 Transmission Seal we have in stock is the Manual Transmission Output Shaft Seal. It costs $3.49.

What types of Transmission Seals do you sell for my 2001 Lexus RX300?

As of 11/2/25, these are some of the most in-demand types of Transmission Seals for a 2001 Lexus RX300:

Can I get help with 2001 Lexus RX300 Transmission Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Transmission Seals and more.

What is your return policy for Lexus RX300 Transmission Seals?

Advance Auto Parts keeps returns simple. For new Lexus RX300 Transmission Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.