2001 Lexus IS300 Transmission Seals

Keep Your 2001 Lexus IS300 in Top Shape with Quality Transmission Seals

Whether you’re repairing or upgrading your Transmission Seal, using high-quality parts is key to keeping your 2001 Lexus IS300 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Miscellaneous Shift Shaft Seals, Extension Housing Seals, and Shaft Seals. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2001 Lexus IS300 Transmission Seal at Advance Auto Parts is around $7.49, with a range that starts at $4.49 and goes up to $10.99. With 4 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like Multi Purpose Seal, Multi-Purpose Seal, and Auto Transmission Manual Shaft Seal start at just $6.49 and offer a great balance of form and function.

Essential 2001 Lexus IS300 Transmission Seals

National – Multi Purpose Seal (Part No.221207)

Multi Purpose Seal

from

$10.99
Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

ATP – AT EXT HOUSING SEAL (Part No.RO-77)

AT EXT HOUSING SEAL

from

$19.99
AT EXT HOUSING SEAL

Driveworks – Auto Transmission Extension Housing Seal (Rear Seal) (Part No.S-224205)

Auto Transmission Extension Housing Seal (Rear Seal)

from

$4.49
Product Features:
  • Brand may vary by location
See More

National – Multi-Purpose Seal (Part No.224205)

Multi-Purpose Seal

from

$7.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)

Auto Transmission Manual Shaft Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

Most Popular Miscellaneous Shift Shaft Seal for 2001 Lexus IS300s

Enhance your 2001 Lexus IS300 with this popular Miscellaneous Shift Shaft Seal we have in stock, for $10.99.

National – Multi Purpose Seal (Part No.221207)

Multi Purpose Seal

from

$10.99
Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Best-Selling 2001 Lexus IS300 Extension Housing Seals

Upgrade your IS300 with one of our 2 best-selling Extension Housing Seals.

National – Multi-Purpose Seal (Part No.224205)

Multi-Purpose Seal

from

$7.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Auto Transmission Extension Housing Seal (Rear Seal) (Part No.S-224205)

Auto Transmission Extension Housing Seal (Rear Seal)

from

$4.49
Product Features:
  • Brand may vary by location
See More

Top-Quality Shaft Seals for 2001 Lexus IS300s

Choose a high-quality OEM or aftermarket Shaft Seal for Lexus IS300s and enjoy top-notch performance from $6.49.

Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)

Auto Transmission Manual Shaft Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

FAQs for 2001 Lexus IS300 Transmission Seals

What are the best-selling Transmission Seals for 2001 Lexus IS300s?

Out of 4 Transmission Seals that fit 2001 Lexus IS300s, the following parts are the top sellers:

What’s the price range for 2001 Lexus IS300 Transmission Seals?

The prices of Transmission Seals for the 2001 Lexus IS300 range from $4.49 up to $10.99 for the most premium parts.

What is the average price of a Transmission Seal for a 2001 Lexus IS300?

The average price for Transmission Seals for the 2001 Lexus IS300 is $7.49. Keep in mind the variety of part types within our Transmission Seal category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Transmission Seals for other Lexus IS300 model years?

Yes, we carry Transmission Seals for 8 model years of Lexus IS300s between 2002 and 2020. The following model years are the most popular for Transmission Seal purchases: 2020, 2019, 2018, 2017, 2016, 2005, 2004, 2003, and 2002.

What are the cheapest Transmission Seals for my 2001 Lexus IS300?

The cheapest 2001 Lexus IS300 Transmission Seals we carry are:

Does Advance Auto Parts sell Transmission Seals for any other 2001 Lexus models?

Yes. We stock Transmission Seals for 5 other popular 2001 Lexus models. Some of the most popular are 2001 ES300 Transmission Seals, 2001 GS300 Transmission Seals, 2001 RX300 Transmission Seals, 2001 LS430 Transmission Seals, and 2001 LX470 Transmission Seals.

What types of Transmission Seals do you sell for my 2001 Lexus IS300?

As of 11/2/25, these are some of the most in-demand types of Transmission Seals for a 2001 Lexus IS300:

Can I get help with 2001 Lexus IS300 Transmission Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Transmission Seals and more.

What is your return policy for Lexus IS300 Transmission Seals?

Advance Auto Parts keeps returns simple. For new Lexus IS300 Transmission Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.