2001 GMC Sierra 2500 HD Keys

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Keep Your 2001 GMC Sierra 2500 HD in Top Shape with Quality Keys

Whether you’re repairing or upgrading your Key, using high-quality parts is key to keeping your 2001 GMC Sierra 2500 HD looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Alarm and Keyless Entry Transmitters, Remote Key Housings, and Vehicle Keys. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Keys from Trusted Brands

Looking for a reliable Key? We’ve got you covered with options from brands you know and trust like Dorman. For example, Dorman Keys start at just $63.99 with an average 4.2 star rating. With over 9 reviews and a solid 5.0 star average, you can shop with confidence knowing other GMC Sierra 2500 HD owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2001 GMC Sierra 2500 HD Key at Advance Auto Parts is around $51.93, with a range that starts at $17.99 and goes up to $113.99. With 8 options in stock from 3 trusted brands, finding the right fit is easy. Popular picks like iKeyless Universal Car Remote, URCR01SINGLEBOX, Dorman – Help Keyless Remote Case, 13622, and Car Keys Express Universal EZ Installer, UNEZ-0BX start at just $21.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Key, don’t forget to check out other key components like Covers and Storage and Cargo Products. At Advance Auto Parts, we’re here to help you keep your 2001 GMC Sierra 2500 HD in peak condition, inside and out.

Essential 2001 GMC Sierra 2500 HD Keys

Dorman – Help – Dorman – Help Keyless Entry Remote – 4 Button, 13719 (Part No.13719)

Dorman - Help Keyless Entry Remote - 4 Button, 13719

from

$75.99
Need a new key fob- This DIY keyless remote is designed to match the appearance and function of the original on specific vehicle years, makes, models and configurations. With easy-to-follow instructions, you can program it yourself in minutes, and rely on it for years.
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iKeyless – iKeyless Universal Car Remote, URCR01SINGLEBOX (Part No.URCR01SINGLEBOX)

iKeyless Universal Car Remote, URCR01SINGLEBOX

from

$36.49
The name says it all – the Universal Car Remote works like a universal TV remote, but itft.s made for cars. Itft.s designed to work with factory-installed keyless entry systems. It works exactly like a vehicleft.s original factory remote, unlocking and locking doors, popping open the trunk – everything an original remote does. The Universal Car Remote has the capabilities of 216 remotes packed into a single device. It replaces factory original remotes for vehicles made by 21 car manufacturers – from Buick to Volkswagen. For the first time ever, you can replace remotes using a single device.
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Dorman – Help – Dorman – Help Keyless Entry Remote with DIY Programming- 4 Button (OE Fix), 99162 (Part No.99162)

Dorman - Help Keyless Entry Remote with DIY Programming- 4 Button (OE Fix), 99162

from

$128.99
Need a new keyless remote- This fob is designed to look and function exactly like your original, and you don’t need to pay for expensive programming at the car dealership. This Dorman OE FIX replacement includes a patented, DIY-friendly programming tool for simple replacement. Just plug it into the OBD II port in your dashboard, follow the included instructions, and you’re good to go. Setup takes minutes, and you can rely on your new remote for years.
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iKeyless – iKeyless Cadillac/Chevrolet/GMC Keyless Entry Remote – 3 Button, GM790 (Part No.GM790)

iKeyless Cadillac/Chevrolet/GMC Keyless Entry Remote - 3 Button, GM790

from

$61.99
This item is a genuine OEM (Original Equipment Manufacturer) remote that operates your vehicleft.s keyless entry system. This clicker features 3 buttons: LOCK, UNLOCK, and PANIC. This key fob includes a fresh battery, offering prolonged performance and a wide physical range of operation. This clicker enhances security and vehicle entry for all drivers.
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Dorman – Dorman Keyless Entry Remote 5 Button, 99443ST (Part No.99443ST)

Dorman Keyless Entry Remote 5 Button, 99443ST

from

$210.99
This keyless entry remote is designed to match the appearance and function of the original key fob on specified vehicles, providing a nearly identical replacement or spare transmitter. It requires programming with a compatible scan tool to be paired with a vehicle. Setup by a qualified and properly equipped professional is recommended.
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Dorman – Help – Dorman – Help Keyless Entry Remote – 3 Button (OE Fix), 99161 (Part No.99161)

Dorman - Help Keyless Entry Remote - 3 Button (OE Fix), 99161

from

$102.99
Need a new keyless remote- This fob is designed to look and function exactly like your original, and you don’t need to pay for expensive programming at the car dealership. This Dorman OE FIX replacement includes a patented, DIY-friendly programming tool for simple replacement. Just plug it into the OBD II port in your dashboard, follow the included instructions, and you’re good to go. Setup takes minutes, and you can rely on your new remote for years.
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Dorman – Dorman Keyless Entry Remote 4 Button, 99446ST (Part No.99446ST)

Dorman Keyless Entry Remote 4 Button, 99446ST

from

$148.99
This keyless entry remote is designed to match the appearance and function of the original key fob on specified vehicles, providing a nearly identical replacement or spare transmitter. It requires programming with a compatible scan tool to be paired with a vehicle. Setup by a qualified and properly equipped professional is recommended.
See More

Dorman – Dorman Keyless Entry Remote 4 Button, 99444ST (Part No.99444ST)

Dorman Keyless Entry Remote 4 Button, 99444ST

from

$196.99
This keyless entry remote is designed to match the appearance and function of the original key fob on specified vehicles, providing a nearly identical replacement or spare transmitter. It requires programming with a compatible scan tool to be paired with a vehicle. Setup by a qualified and properly equipped professional is recommended.
See More

Dorman – Help – Dorman – Help Keyless Entry Remote – 3 Button, 13739 (Part No.13739)

Dorman - Help Keyless Entry Remote - 3 Button, 13739

from

$63.99
Need a new key fob- This DIY keyless remote is designed to match the appearance and function of the original on specific vehicle years, makes, models and configurations. With easy-to-follow instructions, you can program it yourself in minutes, and rely on it for years.
See More

iKeyless – iKeyless GM Keyless Entry Remote – 4 Button with Trunk, GM660 (Part No.GM660)

iKeyless GM Keyless Entry Remote - 4 Button with Trunk, GM660

from

$72.99
Looking for a spare key fob? Weft.ve got you covered! This transmitter device operates your vehicleft.s keyless entry system with four button functions: LOCK, UNLOCK, TRUNK, and PANIC. The clickerft.s durable case is meant to withstand everyday use while keeping internal electronics protected. This remote enhances both vehicle security and entry with a small click of a button. Easy! It has a freshly installed battery and is able to emit signals from a range of distances. This fob makes a great gift for both new and experienced drivers.
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Dorman – Help – Dorman – Help Keyless Remote Case, 13622 (Part No.13622)

Dorman - Help Keyless Remote Case, 13622

from

$21.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
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iKeyless – iKeyless GM Black Replacement Remote Shell – 6 Buttons, GMMT1066 (Part No.GMMT1066)

iKeyless GM Black Replacement Remote Shell - 6 Buttons, GMMT1066

from

$10.99
One brand new, aftermarket replacement remote case. There are no electronics included. You can simply replace the old case on your old remote. Just take the insides out and put them in this shell. Do not pay the dealer $250 for another remote if your case just worn out or broken! This remote case is for remotes with 6 buttons: LOCK, UNLOCK, HATCH, HATCH GLASS, REMOTE START, and PANIC. Compatible Vehicles include but not limited to: Chevrolet Suburban (2014-2020) Chevrolet Tahoe (2014-2020) GMC Acadia (2014-2018) GMC Sierra (2015-2018) GMC Yukon (2015-2020)
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Dorman – Help – Dorman – Help Protective Remote Cover, 95642 (Part No.95642)

Dorman - Help Protective Remote Cover, 95642

from

$10.99
Cracked or wore out your key fob case? Want to add a custom look or differentiate between multiple keys? Simply install these silicone protective remote covers over your hard plastic OE remote case in seconds without any tools. Convenient and affordable, these keyless entry transmitter covers can be used to restore or enhance the look of your existing keyless remote, and the precision fit helps to keep moisture and debris out while protecting the fob from casual drops, scratches, and damage. Two silicone covers (one black, and one blue) are included in each package.
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Dorman – Help – Dorman – Help Keyless Remote Case, 13618 (Part No.13618)

Dorman - Help Keyless Remote Case, 13618

from

$20.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

iKeyless – iKeyless Replacement GM Remote Shell,5 Buttons, GMRB-31RE (Part No.GMRB-31RE)

iKeyless Replacement GM Remote Shell,5 Buttons, GMRB-31RE

from

$21.49
Car Remote Replacement Case. Replaces OEM factory-original remote case. Match by appearance. Electronics not included. GM 5 Button Black Shell Only; No Electronics.
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Dorman – Help – Dorman – Help Keyless Remote Cases Repair, 92025 (Part No.92025)

Dorman - Help Keyless Remote Cases Repair, 92025

from

$29.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

Dorman – Help – Dorman – Help Keyless Remote Case, 13621 (Part No.13621)

Dorman - Help Keyless Remote Case, 13621

from

$14.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

Dorman – Help – Dorman – Help Keyless Remote Case, 13618GYC (Part No.13618GYC)

Dorman - Help Keyless Remote Case, 13618GYC

from

$21.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

iKeyless – iKeyless GM Black Replacement Remote Shell – 5 Buttons, GMRB-5TR0RE (Part No.GMRB-5TR0RE)

iKeyless GM Black Replacement Remote Shell - 5 Buttons, GMRB-5TR0RE

from

$11.99
One brand new, aftermarket replacement remote case. There are no electronics included. You can simply replace the old case on your old remote. Just take the insides out and put them in this shell. Do not pay the dealer $250 for another remote if your case just worn out or broken! This remote case is for remotes with 5 buttons: LOCK, UNLOCK, REMOTE START, TRUNK, and PANIC. Compatible Vehicles include but not limited to: Buick Enclave (2008-2017) Buick Lucerne (2006-2011) Cadillac DTS (2006-2009) Cadillac Escalade (2007-2013) Chevrolet Equinox (2010) Chevrolet Express (2008-2018) Chevrolet Impala (2006-2013) Chevrolet Impala Limited (2014-2016) Chevrolet Malibu (2011-2013) Chevrolet Monte Carlo (2006-2007) Chevrolet Suburban (2007-2014) Chevrolet Tahoe (2007-2014) Chevrolet Traverse (2009-2017) GMC Acadia (2007-2017) GMC Savana (2008-2021) GMC Sierra (2008-2011) GMC Terrain (2017) GMC Yukon (2007-2014) GMC Yukon Denali (2007-2010) Hummer H2 (2008) Saturn Outlook (2007-2010)
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Car Keys Express – Car Keys Express Universal EZ Installer, UNEZ-0BX (Part No.UNEZ-0BX)

Car Keys Express Universal EZ Installer, UNEZ-0BX

from

$69.99
The Universal EZ Installer is a Fob & Remote Pairing OBD Programmer Tool for Specific Vehicles. Modern car keys need to be electronically paired to a vehicle in order to work. Before the EZ Installer, this meant an expensive trip to the dealership to use their special computers. Not anymore. The EZ Installer does the same thing in minutes using an app on your phone.
See More

Dorman – Help – Dorman – Help Keyless Remote Case, American Flag, 13618US (Part No.13618US)

Dorman - Help Keyless Remote Case, American Flag, 13618US

from

$21.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

iKeyless – iKeyless GM Black Replacement Remote Shell – 3 Buttons, GMRB-35RE (Part No.GMRB-35RE)

iKeyless GM Black Replacement Remote Shell - 3 Buttons, GMRB-35RE

from

$10.99
One brand new, aftermarket replacement remote case. There are no electronics included. You can simply replace the old case on your old remote. Just take the insides out and put them in this shell. Do not pay the dealer $250 for another remote if your case just worn out or broken! This remote case is for remotes with 3 buttons: LOCK, UNLOCK, and PANIC. Compatible Vehicles include but not limited to: Buick Enclave (2007-2017) Cadillac Escalade (2008) Chevrolet Avalanche (2007-2014) Chevrolet Caprice (2013-2014) Chevrolet Captiva (2011-2015) Chevrolet Equinox (2007-2009) Chevrolet Express (2008-2022) Chevrolet Silverado (2007-2014) Chevrolet Sonic (2012) Chevrolet Traverse (2009-2017) Chevrolet Trax (2015) GMC Acadia (2007-2017) GMC Savana (2007-2020) GMC Sierra (2007-2014) Hummer H2 (2008) Pontiac Torrent (2007-2009) Saturn Outlook (2007-2011) Saturn Vue (2008-2011) Suzuki XL-7 (2007-2009)
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iKeyless – iKeyless GM Black Replacement Remote Shell – 4 Buttons, GMMT969 (Part No.GMMT969)

iKeyless GM Black Replacement Remote Shell - 4 Buttons, GMMT969

from

$13.99
One brand new, aftermarket replacement remote case. There are no electronics included. You can simply replace the old case on your old remote. Just take the insides out and put them in this shell. Do not pay the dealer $250 for another remote if your case just worn out or broken! This remote case is for remotes with 4 buttons: LOCK, UNLOCK, REMOTE START, and PANIC. Compatible Vehicles include but not limited to: Buick Enclave (2007-2017) Cadillac Escalade (2008-2010) Cadillac Escalade EXT (2007) Chevrolet Avalanche (2007-2014) Chevrolet Caprice (2014) Chevrolet Captiva (2011-2015) Chevrolet Equinox (2007-2009) Chevrolet Express (2008-2019) Chevrolet Impala (2007) Chevrolet Monte Carlo (2006-2007) Chevrolet Silverado (2007-2014) Chevrolet Suburban (2008-2011) Chevrolet Tahoe (2007-2014) Chevrolet Traverse (2009-2017) GMC Acadia (2007-2017) GMC Canyon (2014) GMC Savana (2008-2017) GMC Sierra (2007-2014) GMC Yukon (2008-2011) Hummer H2 (2008) Pontiac Torrent (2007-2009) Saturn Outlook (2007-2011) Saturn Vue (2008-2011) Suzuki XL-7 (2008)
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Dorman – Help – Dorman – Help Keyless Remote Case, Mexico Flag, 13618MX (Part No.13618MX)

Dorman - Help Keyless Remote Case, Mexico Flag, 13618MX

from

$14.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

Most Popular Alarm and Keyless Entry Transmitters for 2001 GMC Sierra 2500 HDs

Enhance your 2001 GMC Sierra 2500 HD with one of the 5 Alarm and Keyless Entry Transmitters we have in stock, starting at just $17.99.

Dorman – Help – Dorman – Help Keyless Entry Remote – 3 Button, 13739 (Part No.13739)

Dorman - Help Keyless Entry Remote - 3 Button, 13739

from

$63.99
Need a new key fob- This DIY keyless remote is designed to match the appearance and function of the original on specific vehicle years, makes, models and configurations. With easy-to-follow instructions, you can program it yourself in minutes, and rely on it for years.
See More

iKeyless – iKeyless Universal Car Remote, URCR01SINGLEBOX (Part No.URCR01SINGLEBOX)

iKeyless Universal Car Remote, URCR01SINGLEBOX

from

$36.49
The name says it all – the Universal Car Remote works like a universal TV remote, but itft.s made for cars. Itft.s designed to work with factory-installed keyless entry systems. It works exactly like a vehicleft.s original factory remote, unlocking and locking doors, popping open the trunk – everything an original remote does. The Universal Car Remote has the capabilities of 216 remotes packed into a single device. It replaces factory original remotes for vehicles made by 21 car manufacturers – from Buick to Volkswagen. For the first time ever, you can replace remotes using a single device.
See More

iKeyless – iKeyless Replacement GM Keyless Entry Remote with EZ Installer, 4 Buttons with Additional Button Kits, GMRM-4TZ0RE (Part No.GMRM-4TZ0RE)

iKeyless Replacement GM Keyless Entry Remote with EZ Installer, 4 Buttons with Additional Button Kits, GMRM-4TZ0RE

from

$113.99
GM Keyless entry replacement remote with pairing device included. Replaces vehicle manufacturerft.s original remote. This package comes with two different 4-button pads + additional top shell with a 3-button option. The EZ Installer DIY pairing dongle allows you to pair your remote entirely on your own. Avoid the hassle and expense of having to go to the dealership for pairing. The EZ Installer is a single vehicle use pairing tool. Once you use it on your vehicle, it cannot be used on another. Includes: Standard Button Pad: 4 Buttons (Lock, Unlock, Trunk, & Panic), Additional included Button Pad functions: Buttons (Lock, Unlock, Fuel Door Release, & Trunk), Additional Top Shell & Button Pad: 3 Buttons (Lock, Unlock, & Panic).
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Dorman – Help – Dorman – Help Keyless Remote Case, 13622GNC (Part No.13622GNC)

Dorman - Help Keyless Remote Case, 13622GNC

from

$17.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

Dorman – Help – Dorman – Help Keyless Remote Case, 13622GYC (Part No.13622GYC)

Dorman - Help Keyless Remote Case, 13622GYC

from

$17.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

Best-Selling 2001 GMC Sierra 2500 HD Remote Key Housings

Upgrade your Sierra 2500 HD with one of our 2 best-selling Remote Key Housings.

Dorman – Help – Dorman – Help Keyless Remote Case, 13622 (Part No.13622)

Dorman - Help Keyless Remote Case, 13622

from

$21.99
Cracked or wore out your key fob case- Want to add a custom look- Just replace the case with this convenient, affordable keyless entry transmitter cover, restoring or enhancing the look.
See More

Car Keys Express – Car Keys Express Universal EZ Installer, UNEZ-0BX (Part No.UNEZ-0BX)

Car Keys Express Universal EZ Installer, UNEZ-0BX

from

$69.99
The Universal EZ Installer is a Fob & Remote Pairing OBD Programmer Tool for Specific Vehicles. Modern car keys need to be electronically paired to a vehicle in order to work. Before the EZ Installer, this meant an expensive trip to the dealership to use their special computers. Not anymore. The EZ Installer does the same thing in minutes using an app on your phone.
See More

Top-Quality Vehicle Keys for 2001 GMC Sierra 2500 HDs

Choose a high-quality OEM or aftermarket Vehicle Key for GMC Sierra 2500 HDs and enjoy top-notch performance from $72.99.

iKeyless – iKeyless GM Keyless Entry Remote – 4 Button with Trunk, GM660 (Part No.GM660)

iKeyless GM Keyless Entry Remote - 4 Button with Trunk, GM660

from

$72.99
Looking for a spare key fob? Weft.ve got you covered! This transmitter device operates your vehicleft.s keyless entry system with four button functions: LOCK, UNLOCK, TRUNK, and PANIC. The clickerft.s durable case is meant to withstand everyday use while keeping internal electronics protected. This remote enhances both vehicle security and entry with a small click of a button. Easy! It has a freshly installed battery and is able to emit signals from a range of distances. This fob makes a great gift for both new and experienced drivers.
See More

Top-Rated Key Brands For Your 2001 GMC Sierra 2500 HD

When it comes to finding the perfect Key for your 2001 GMC Sierra 2500 HD, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 3 trusted brands. We carry the most popular Key brands including Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.2 stars) and competitive prices, as low as $63.99. Purchasing a Key from us here at Advance Auto Parts is a smart move for both you and your 2001 GMC Sierra 2500 HD, providing peace of mind with parts that meet or exceed OEM standards.

Popular Dorman 2001 GMC Sierra 2500 HD Keys

If you’re looking for a top-quality Key for your 2001 GMC Sierra 2500 HD, Advance Auto Parts has exactly what you need with our selection of Dorman Keys. We have 1 Dorman Keys in stock for this fitment, all known for their durability and precision fit. With prices starting at just $63.99, you’ll find the perfect Key for your needs and budget. Dorman Keys for the 2001 GMC Sierra 2500 HD come highly rated, with over 1 customer reviews and an impressive average rating of 4.2 stars. Choosing a Dorman Key from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.

FAQs for 2001 GMC Sierra 2500 HD Keys

What are the best-selling Keys for 2001 GMC Sierra 2500 HDs?

Out of 8 Keys that fit 2001 GMC Sierra 2500 HDs, the following parts are the top sellers:

What’s the price range for 2001 GMC Sierra 2500 HD Keys?

The prices of Keys for the 2001 GMC Sierra 2500 HD range from $17.99 up to $113.99 for the most premium parts.

What is the average price of a Key for a 2001 GMC Sierra 2500 HD?

The average price for Keys for the 2001 GMC Sierra 2500 HD is $51.93. Keep in mind the variety of part types within our Key category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Keys for other GMC Sierra 2500 HD model years?

Yes, we carry Keys for 21 model years of GMC Sierra 2500 HDs between 2002 and 2023. The following model years are the most popular for Key purchases: 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, and 2012.

What are the cheapest Keys for my 2001 GMC Sierra 2500 HD?

The cheapest 2001 GMC Sierra 2500 HD Keys we carry are:

Does Advance Auto Parts sell Keys for any other 2001 GMC models?

Yes. We stock Keys for 11 other popular 2001 GMC models. Some of the most popular are 2001 Yukon Keys, 2001 Sierra 1500 Keys, 2001 Yukon XL 1500 Keys, 2001 Yukon XL 2500 Keys, and 2001 Savana 1500 Keys.

What are the top-rated Keys that fit the 2001 GMC Sierra 2500 HD?

The one 2001 GMC Sierra 2500 HD Key we have in stock is the Dorman – Help Keyless Remote Case, 13622GNC. It costs $17.99.

What types of Keys do you sell for my 2001 GMC Sierra 2500 HD?

As of 8/2/26, these are some of the most in-demand types of Keys for a 2001 GMC Sierra 2500 HD:

Can I get help with 2001 GMC Sierra 2500 HD Key orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about GMC Keys and more.

What is your return policy for GMC Sierra 2500 HD Keys?

Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Keys and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.