2001 GMC Sierra 2500 HD Differentials

Please Select your Vehicle to See Exact Fit Parts

Keep Your 2001 GMC Sierra 2500 HD in Top Shape with Quality Differentials

Whether you’re repairing or upgrading your Differential, using high-quality parts is key to keeping your 2001 GMC Sierra 2500 HD looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Differential Bearings, Differential Covers, and Rear Differential Cover Gaskets. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Differentials from Trusted Brands

Looking for a reliable Differential? We’ve got you covered with options from brands you know and trust like Dorman, National, and Felpro. For example, Dorman Differentials start at just $46.99 with an average 4.2 star rating. National and Felpro offer similar pricing and quality, backed by strong customer feedback. With over 7,092 reviews and a solid 4 star average, you can shop with confidence knowing other GMC Sierra 2500 HD owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2001 GMC Sierra 2500 HD Differential at Advance Auto Parts is around $489.22, with a range that starts at $2.99 and goes up to $4,070.00. With 257 options in stock from 17 trusted brands, finding the right fit is easy. Popular picks like Taper Bearing Cone, Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket, and Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket start at just $8.29 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Differential, don’t forget to check out other key components like 4WD Components and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2001 GMC Sierra 2500 HD in peak condition, inside and out.

Looking for the perfect Differential for your 2001 GMC Sierra 2500 HD? You’re in the right place. Below, you’ll find links to various types of Differentials that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Differentials, ensuring durability and a precise fit for your GMC Sierra 2500 HD. Whether you’re driving a 2001 model or another popular model year like 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, and 2023, we’ve got you covered. Purchasing Differentials from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Differentials that fit your vehicle.

Essential 2001 GMC Sierra 2500 HD Differentials

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$44.99

3 Qt. Penzoil 80W90 conventional gear Oil.

Product Features:

Includes three quarts of conventional oil

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$211.99

Product Features:

GM10.5″ 14 BOLT OPEN EMPTY CASE 4:10 & DWN

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$6.79

This differential pinion shaft lock bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this differential pinion shaft lock bolt matches the fit and function of the factory part on specified years, makes and models
Ideal solution – this bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$1929.99

The Yukon Grizzly Locker is the ultimate in locking differentials for street, off-road, & drag racing. Grizzly Lockers provide 100% power to both tires, while still allowing for disengagement while negotiating turns. The factory spindles will need to be machined in order to accept the axles this locker uses. The Yukon Grizzly locker is a mechanical locking differential. It features a forged case and 8620 internals for maximum strength. It’s patented design reduces common locker failures. All units assembled in the USA! All Grizzly Lockers are backed by the best warranty in the business! Yukon covers the replacement unit and covers any collaterally damaged parts and associated labor, up to $2,000!

Product Features:

Fits GM and Chrysler 11.5″ with 38 spline axles
Patented internal design reduces common locker failures
8620 internals for added strength
Assembled in the USA

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$5.99

DiffrlPinSupportBolt

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$74.99

11.5″ GM & Chrysler crush sleeve. Approx 0.935″ long.

Product Features:

Crush sleeve for GM and Chrysler 11.5″
0.935″ tall

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$3.99

Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:

Meets or exceeds OE specifications

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$32.99

Product Features:

Cross pin shaft
Fits GM 9.5″
Dura Grip positraction

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$1806.99

11.5″ Chrysler Helical gear Type positraction.

Product Features:

Fits GM and Chrysler 11.5″
30 spline

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$449.99

Yukon Pinion installation kits are a terrific solution for gear installation on lower mileage vehicles where the carrier bearings & races can be reused. This kit uses Timken bearings and races along with a high quality pinion seal and small parts. Included in this kit are the pinion bearings and races, pilot bearing (if applicable), crush sleeve (if applicable), complete pinion shim kit, thread locker, and marking compound with brush. Yukon does extensive research for each application to make sure your kit will arrive with all the correct parts you need to install your pinion gear.

Product Features:

Fits 1998 and up GM 10.5″ 14 bolt truck
Included are pinion bearings and races, pinion seal, crush sleeve, complete pinion shim kit, and marking compound with brush.

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$25.99

10.5″ & 11.5″ GM & Dodge pinion seal.Yukon Mighty seal.

Product Features:

Pinion seal
Fits Chrysler 10.5″ and 11.5″

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$487.99

The Powertrax Lock-Right ultra-strength alloy locker’s straight-line performance is equal to a solid spool, but automatically unlocks in turns. Best suited for extreme off-road to severe on-road use, Powertrax Lock Right lockers replace the spider gears in your open differential carrier using basic tools and without affecting your ring and pinion settings. The whole job can be done in your driveway in a couple of hours, pin included! Powertrax Grip-Lok, Lock-Right Lockers and No-Slip Traction Systems automatically provide 100% traction on-demand, under the toughest circumstances. The Powertrax Grip-Pro and Grip-LS performance limited slips offer smooth dependable torque transfer and traction for the best of both worlds!

Product Features:

Powertrax® proves that you don’t have to choose between the superior traction of a locking differential and smooth handling and drivability of an open differential. Powertrax Lock-Right Lockers, No-Slip Traction Systems and GRIP limited slip differentials and lockers give you the best of both worlds!
The Powertrax® Lock-Right Locker provides outstanding traction for off-road machines and race vehicles. Powertrax No-Slip Traction Systems deliver excellent performance to street-driven cars and trucks.
Powertrax® lockers range from the original, Lock-Right for serious straight-line performance, to the No-Slip traction system for street-able vehicles.
Powertrax® offers three levels of GRIP locking differentials, ranging from the clutch-type GRIP LS with a forged steel case, the gear-driven GRIP PRO and finally the GRIP LOK for extreme traction.
Powertrax® = Extreme Traction Systems!

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$539.99

Yukon Performance steel spool for GM 14T with 30 spline axles. fits 4.10 and down. Yukon performance spools are made from the highest quality materials to ensure high strength and long life in performance applications. Spools provide 100% power to both tires at all times and are a lower cost alternative to lockers. Spools are not recommended for street driven vehicles. Yukon Performance spools come with a one year warranty against manufacturing defects.

Product Features:

Fits GM 10.5″ 14 bolt truck with 30 spline axles
4.10 and down ratio only or 4.56 and up thick gears
Provides 100% traction to both wheels at all times
Not recommended for street driven vehicles

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$232.99

Worn or damaged differential end yoke causing driveline Vibrations! This direct replacement end yoke matches the original equipment part for a trustworthy repair and reliable performance.

Product Features:

Direct replacement – this differential end yoke matches the fit and construction of the original yoke
Excellent value – this replacement end yoke offers original equipment quality at a fraction of the price of dealer parts
Quality materials – this end yoke is machined from cast iron for strength and is precision machined for reliability
Validated fit – this differential end yoke has been tested to confirm accurate fit

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$115.99

9.25IFS GM 11 & up side bearing adjuster.

Product Features:

Side adjuster
Fits 2011 and up GM 9.25″ IFS

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$1007.99

This differential ring and pinion directly replaces the original equipment on specific vehicle years, makes and models.

Product Features:

Direct replacement – this ring and pinion set matches the fit and function of the original components on certain vehicle applications
Effective fix – eliminates grinding and whining from failed original bearings
Thoroughly tested – vehicle try-on testing and rigorous quality control measures ensure longevity
Trustworthy quality – backed by team of designers and engineers in the United States

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$561.99

Yukon spider gear set for GM 9.5″ Gura Drip posi. This kit does not include clutches. This kit fits Yukon Dura Grip ONLY.

Product Features:

Spider gear kit
Fits GM 9.5″ with Dura Grip positraction
Includes two side gears, four pinion gears, cross pin shaft, roll pin and spider gear thrust washers.

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$8.29

Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered for the sealing repair environment
Validated for fit, form and function
Unsurpassed quality you can trust

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$46.99

This direct replacement differential cover matches the fit and function of the original equipment diff cover for a reliable, leak-free repair. It features a durable design, made to strict specifications, to help ensure reliable service life.

Product Features:

Direct replacement – this differential cover matches the fit and function of the original equipment diff cover on select vehicles
Reliable repair – the smart solution for fixing an existing cover that’s rusted, damaged or leaking differential fluid
Durable construction – this differential cover is made according to strict engineering standards to help ensure dependability
Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience

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$31.99

11.5″ GM standard Open side gear Thrust washer.

Product Features:

Side gear thrust washer
Fits GM 11.5″

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$37.99

Product Features:

Pinion nut for GM and Chrysler 11.5″
12 point 36mm socket

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$7.99

Differential Cover B

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$29.99

9.5″ GM differential carrier Supershim kit.

Product Features:

Super carrier shim kit for GM 9.5″
Interlocking design makes installation much easier

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$28.49

Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

Product Features:

PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
SMOOTH ROTATION – Crowned raceways for even load distribution
OE-STYLE DESIGN – Engineered to meet OE specifications
COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on

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$32.99

Adjuster lock bolt for left hand case half of 7.2″ and 9.25″ GM IFS.

Product Features:

Side adjuster lock bolt
Fits GM 7.2″ IFS and 9.25″ IFS

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$401.99

This axle shaft directly replaces the original equipment on certain vehicles, complete with all necessary application-specific installation components.

Product Features:

Direct replacement – this axle shaft replaces the original equipment on specific vehicle years, makes and models
Complete kit – each shaft includes critical installation hardware and components needed for specific vehicle applications
Durable construction – designed to rigorous standards and tested to ensure performance
Trustworthy solution – backed by team of engineers and quality control specialists in the United States

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$594.99

USA Standard Master Overhaul kits let you finish your install with confidence. This kit uses Koyo bearings and races. Included are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), threading locking compound, marking compound with brush and gasket.

Product Features:

Fits 2010 and down GM 9.25″ IFS
Uses Koyo bearings and races
Included are carrier bearings and races, pinion bearings and races, pinion seal, axle seals, complete shim kit, ring gear bolts, pinion nut, crush sleeve, thread locker, marking compound with brush and silicone.

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$581.99

Fits 2010 and down GM and Chrysler 11.5″
Uses Koyo bearings and races
Included are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, pinion nut, crush sleeve, thread locker, marking compound with brush and silicone.

Popular 2001 GMC Sierra 2500 HD Differentials Categories

Differential Oil

Rear Differential Cover Gaskets

Differential Open Unit and Components

Differential Covers

Differential Pinion Shaft Lock Bolts

Differential Bearings

Differential Axle Shafts

Differential Pinion Pilot Bearings

Differential Cover Bolts

Differential Carriers

Differential Bearing Kits

Front Differential Pinion Bearings

Differential Spider Gear Kits

Differential Rebuild Kits

Differential Carrier Shim Kits

Differential Pinion Seals

Differential Clutch Packs

Differential Ring and Pinions

Differential Cases

Differential End Yokes

Differential Lock Assemblies

Rear Differential Pinion Bearings

Differential Spools

Differential Carrier Bearing Adjusters

Rear Housing Cover Gaskets

Differential Pinion Bearing Kits

Differential Ring Gear Bolts

Differential Crush Sleeves

Differential Side Bearing Spacers

Differential Pinion Shims

Differential Pinion Shaft Nuts

Differential Gear Install Kits

Differential Cross Pins

Differential Housing O-Rings

Differential Side Gear Thrust Washers

Differential Pinion Gear Thrust Washers

Differential Drive Pinion Gear Bearing Retainer Bolts

Differential Ring and Pinion Kits

Limited Slip Differential Assemblies

Differential Spider and Pinion Gear Kits

Differential Bearing Adjuster Nut Lock Bolts

Most Popular Differential Bearings for 2001 GMC Sierra 2500 HDs

Enhance your 2001 GMC Sierra 2500 HD with one of the 4 Differential Bearings we have in stock, starting at just $13.99.

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$13.99

Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

Product Features:

PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
SMOOTH ROTATION – Crowned raceways for even load distribution
OE-STYLE DESIGN – Engineered to meet OE specifications
COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on

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$15.49

Value-priced bearing meets all cataloged application requirements.

Product Features:

Brand may vary by location

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$48.99

Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.

Product Features:

PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
OE-STYLE DESIGN – Engineered to meet OE specifications
COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on

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$20.79

With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:

High-precision and High-quality components used in all KITs
Coverage of classic and new high-tech solutions for the best system coverage

Best-Selling 2001 GMC Sierra 2500 HD Differential Covers

Upgrade your Sierra 2500 HD with one of our 12 best-selling Differential Covers, earning an average 4.83 stars rating across 28 reviews.

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$63.99

Direct replacement – this differential cover matches the fit and function of the original equipment diff cover on select vehicles
Reliable repair – the smart solution for fixing an existing cover that’s rusted, damaged or leaking differential fluid
Durable construction – this differential cover is made according to strict engineering standards to help ensure dependability
Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience

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$89.99

Direct replacement – this differential cover matches the fit and function of the original equipment diff cover on select vehicles
Reliable repair – the smart solution for fixing an existing cover that’s rusted, damaged or leaking differential fluid
Durable construction – this differential cover is made according to strict engineering standards to help ensure dependability
Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience

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$46.99

Direct replacement – this differential cover matches the fit and function of the original equipment diff cover on select vehicles
Reliable repair – the smart solution for fixing an existing cover that’s rusted, damaged or leaking differential fluid
Durable construction – this differential cover is made according to strict engineering standards to help ensure dependability
Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience

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$146.99

Product Features:

Fits GM and Chrysler 11.5″
Steel

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$389.99

Product Features:

Fits Chrysler and GM 11.5″
Finned aluminum

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$92.99

Product Features:

Fits GM 10.5″ 14 bolt truck
Steel

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$59.99

Chrome cover for GM 14T.

Product Features:

Fits GM 10.5″ 14 bolt truck
Chrome

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$40.99

DIFF COVER KIT

Hi-Tek Aluminum Differential Cover for AAM 11.5 - Black

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$506.99

Our engineers designed the line of Hi-Tek differential covers to not only look good but address a number of weaknesses of the factory-stamped steel covers. First, they started by constructing the covers of thick A356.0-T6 aluminum, which dissipates heat much faster than the factory steel unit keeping the fluid temperature lower under high-stress loads vs. a steel cover. Then for added durability, we added a reinforced center bar for extra strength along with load bolts to help prevent bearing cap deflection under severe loads. The internal shape of the cover retains the smooth round back internally to help keep the fluid flow going over the ring gear to properly lubricate the gears and bearings. Additional features include a magnetic drain plug for catching ferrous metal particles, MIL-Spec (MIL-A-8625) black anodized finish, machined B&M logo, all necessary hardware, and easy-to-follow detailed instructions for a quick and simple installation you can do at home.

Product Features:

Load Bolts for Additional Support for Bearing Caps
Magnetic Drain Plug for Easy Servicing
A356.0-T6 Aluminum Construction
Over 65 Years of B&M Quality
Limited Warranty
Additional Fluid Capacity
Black Anodized Finish
Machined B&M Logo

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$354.99

aFe Power’s new rear differential cover brings performance engineering to the protection of your axle’s differential. This differential cover is constructed out of durable cast aluminum with reinforced ribs for maximum strength. This cover comes with all necessary hardware for easy installation. Pro Series differential covers include an oil level sight glass and magnetic deep reach fill plug. This cover is finished with black powder-coating and machined fins for a distinctive look. Increased Oil Capacity: This cover has an increased oil capacity over stock for better performance over a longer duration. Built-in Internal/External Fins: Built-in internal and external fins transfer heat from the oil to the outside air for maximum cooling. Magnetic Plugs: This system incorporates a magnetic drain and deep reach fill plug to capture loose particles for maximum protection. Calibration Plug: Calibration plug set to the factory oil level to eliminate overfilling. Oil Level Sight Glass: A pre-installed oil level sight glass allows quick and easy oil inspection. When it comes to engineering for power, performance, protection and value, aFe Power is the only choice.

Product Features:

Durable Cast Aluminum
Magnetic Drain and Fill Plugs Capture Loose Particles
Calibration Plug Set to Factory Fill Level Eliminates Overfilling
Oil Level Sight Glass for Quick/Easy Inspection

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$354.99

aFe Power’s new rear differential cover brings performance engineering to the protection of your axle’s differential. This differential cover is constructed out of durable A356-T6 cast aluminum with reinforcing ribs for maximum strength. Mounting hardware is included for a hassle-free installation. An oil level sight glass and calibration plug set to the factory level prevents overfilling of the differential. A magnetic drain plug and a deep reach magnetic fill plug are provided for maximum protection. This cover is finished in black powder-coating with machined fins for a distinctive look. 4 Quart Gear Oil Capacity: This cover has about a 4 quart gear oil capacity at the factory fill level, factory cover holds about 3 quarts. Built-in External Fins: Built-in external fins transfer heat from the fluid to the outside air for maximum cooling. Magnetic Drain/Fill Plug: This system incorporates a magnetic drain and deep reach fill plug that captures loose particles for maximum rear-end protection. Oil Level Sight Glass: Large oil level sight glass with 1/8” NPT calibration plug set to the factory fluid level to eliminate overfilling. When it comes to engineering for power, performance, protection and value, aFe Power is the only choice.

Product Features:

Constructed of Durable A356 Die Cast Aluminum
Reinforcing Ribs and Black Powder coating w/Machined Fins
Magnetic Drain and Fill Plugs Capture Loose Particles
Large Oil Level Sight Glass w/ Calibration Plug

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$298.99

aFe Power’s new rear differential cover brings performance engineering to the protection of your axle’s differential. This differential cover is constructed out of durable A356-T6 cast aluminum with reinforcing ribs for maximum strength. Mounting hardware is included for a hassle-free installation. A calibration plug set to the factory level prevents overfilling of the differential. A magnetic drain plug and a deep reach magnetic fill plug are provided for maximum protection. This cover has a raw finish with machined fins for a distinctive look. 4 Quart Gear Oil Capacity: This cover has about a 4 quart gear oil capacity at the factory fill level, factory cover holds about 3 quarts. Built-in External Fins: Built-in external fins transfer heat from the fluid to the outside air for maximum cooling. Magnetic Drain/Fill Plug: This system incorporates a magnetic drain and deep reach fill plug that captures loose particles for maximum rear-end protection. Oil Level calibration plug: A 1/8″ NPT calibration plug is set to the factory fluid level which eliminates accidental overfilling. When it comes to engineering for power, performance, protection and value, aFe Power is the only choice.

Product Features:

Constructed of Durable A356-T6 Cast Aluminum
Reinforcing Ribs w/ a Raw Finish and Machined Fins
Magnetic Drain and Fill Plugs Capture Loose Particles
Calibration Plug Set to Factory Fluid Level

Top-Quality Rear Differential Cover Gaskets for 2001 GMC Sierra 2500 HDs

Choose a high-quality OEM or aftermarket Rear Differential Cover Gasket for GMC Sierra 2500 HDs and enjoy top-notch performance from $3.99.

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from

$8.99

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered for the sealing repair environment
Validated for fit, form and function
Unsurpassed quality you can trust

from

$44.99

11.5″ Chrysler & GM cover gasket.

Product Features:

Cover gasket
Fits GM and Chrysler 11.5″

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$13.99

14T cover gasket.

Product Features:

Cover gasket
Fits GM 10.5″ 14 bolt truck

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$3.99

Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:

Meets or exceeds OE specifications

Top Picks for 2001 GMC Sierra 2500 HD Rear Housing Cover Gaskets

Invest in one of our 2 durable Rear Housing Cover Gaskets for your 2001 GMC, knowing you’re getting trusted brands and expert craftsmanship.

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$15.99

Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Unsurpassed quality you can trust
Validated for fit, form and function
Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes

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$8.29

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered for the sealing repair environment
Validated for fit, form and function
Unsurpassed quality you can trust

Top-Rated Differential Oil for 2001 GMC Sierra 2500 HDs

Make a smart move for your 2001 GMC Sierra 2500 HD with products all priced from $28.99 to $148.99.

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$35.99

Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life. Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, Ford MERCON LV, Toyota/Lexus Type T, T-II, T-IV, WS, Honda/Acura, ATF-Z1, Nissan/Infiniti Matic-D, Matic-J, Matric-K, Matic-S, Hyundai/Kia SP-II, SP-III, SP-IV, SPH-IV, BMW 7045E, ETL 8072B, LA2634, LT71141, Allison C-4, Mercedes Benz NAG-1, Volvo 1161521, 1161540, 97340, 1273.41, and VW/Audi G-052-025-A2, G-052-162-A1. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:

Formulated with full-synthetic base oils and long life friction modifiers to help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
Developed with anti-wear technology to help improve transmission durability
Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures

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$57.99

3 Qt. Penzoil 80W90 conventional gear Oil. W/ bottle of Posi additive.

Product Features:

Includes three quarts of conventional oil and one 4oz bottle of Yukon positraction additive

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$44.99

3 Qt. Penzoil 80W90 conventional gear Oil.

Product Features:

Includes three quarts of conventional oil

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$148.99

Redline Synthetic “Shock Proof” Oil with positraction Additive. 4 Quarts.

Product Features:

Includes four quarts of Redline Shockproof oil and one 4oz bottle of Yukon positraction additive

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$99.99

Redline Synthetic “Shock Proof” Oil. 3 Quarts.

Product Features:

Includes three quarts of Redline Shockproof oil

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$137.99

Redline Synthetic “Shock Proof” Oil. 4 Quarts.

Product Features:

Includes four quarts of Redline Shockproof oil

from

$28.99

Castrol® Transmax® ATF/CVT Universal is a premium full-synthetic transmission fluid engineered for exceptional performance in both traditional step-shifting automatic transmissions and modern continuously variable transmissions (CVTs). Featuring Castrol Smooth Drive® Technology, it ensures enhanced friction durability for seamless gear shifts and superior high-temperature protection to resist oxidation. This advanced formulation offers unmatched protection against copper corrosion, extending the life of your transmission system. Its broad compatibility covers a wide range of ATF and CVT applications, including Dexron VI, Mercon LV, Toyota WS, Honda DW-1, Nissan Matic S, and many more, making it ideal for diverse vehicle types, including hybrids. Designed to improve workshop efficiency and simplify inventory management, this fluid is a versatile solution for professional mechanics and DIY enthusiasts alike. Packaged in a convenient 1-gallon size, it delivers outstanding value and reliability for maintaining optimal transmission performance.

Product Features:

Enhanced friction durability for smooth transmission performance
Superior high temperature protection to effectively resist oxidation
Unsurpassed protection against copper corrosion
Broad scope of vehicle applications improves workshop efficiency and inventory management
ATF Applications: Dexron VI (Dexron III, Dexron), Mercon LV (Mercon SP, Mercon V, Mercon), JASO 1A (03), JASO 1A LV (13), Toyota T IV, Toyota T III, Toyota WS, Honda/Acura DW 1/Z 1, Nissan Matic D, Matic J, Matic S, Hyundai/Kia SP IV, SP III
ATF Applications: Mazda ATF M-V, M-III, FZ, Mitsubishi SP IV, SP III, IIM, II, PA, J3, VW/Audi (6, 8 & 9 speed automatics), BMW/Mini (6, 8 and 9 speed automatics), Jaguar/Land Rover (6, 8 & 9 speed automatics), Porsche (6, 8 & 9 speed automatics)
ATF Applications: Volvo (6, 8 and 9 speed automatics), Volvo Transmission Oil 97342, AT102, Mercedes-Benz (7 and 9 speed automatics)
CVT Applications: Toyota CVT Fluid TC, Toyota CVT Fluid FE , Nissan CVT Fluid NS-1, Nissan CVT Fluid NS-2, Nissan CVT Fluid NS-3, Subaru i-CVT Fluid, Subaru i-CVT FG, Subaru Lineartronic High Torque Chain CVTF, Honda HCF-2

Top-Rated Differential Brands For Your 2001 GMC Sierra 2500 HD

When it comes to finding the perfect Differential for your 2001 GMC Sierra 2500 HD, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 17 trusted brands. We carry the most popular Differential brands including Felpro, National, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $8.29. Purchasing a Differential from us here at Advance Auto Parts is a smart move for both you and your 2001 GMC Sierra 2500 HD, providing peace of mind with parts that meet or exceed OEM standards.

Popular Felpro 2001 GMC Sierra 2500 HD Differentials

If you’re looking for a top-quality Differential for your 2001 GMC Sierra 2500 HD, Advance Auto Parts has exactly what you need with our selection of Felpro Differentials. We have 3 Felpro Differentials in stock for this fitment, all known for their durability and precision fit. With prices starting at just $8.29 and an average cost of $11.09, you’ll find the perfect Differential for your needs and budget. Felpro Differentials for the 2001 GMC Sierra 2500 HD come highly rated, with over 35 customer reviews and an impressive average rating of 4.6 stars. Choosing a Felpro Differential from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.

from $8.99

(20)

Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket

“Perfect fit”

from $8.29

(13)

Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket

“works good”

from $15.99

(2)

Axle Housing Cover Gasket Irregular Shaped 14 Bolt Hole Gasket

“fel pro is best gasket for my purposes”

Top-Quality National 2001 GMC Sierra 2500 HD Differentials

For those in search of a high-quality Differential for their 2001 GMC Sierra 2500 HD, Advance Auto Parts offers a great selection of National Differentials. With 3 National Differentials in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Differentials start at just $13.99, with an average price of $28.99, giving you a range of options to suit your budget. Backed by over 13 customer ratings and an average rating of 4.3 stars, National Differentials provide both reliability and excellent performance. Choosing a National Differential from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.

from $43.99

(2)

Shaft Repair Sleeve

“As a mechanic I dont have time or money to waste on inferior products, which this is not. Great product,great price”

from $28.99

(5)

Multi-Purpose Seal

“How do you fix a leaking rear end? You seal it. That’s why I bought this seal.”

from $13.99

(6)

Bearing Race

“Fit perfectly. No difficulty replacing my old ones.”

FAQs for 2001 GMC Sierra 2500 HD Differentials

What are the best-selling Differentials for 2001 GMC Sierra 2500 HDs?

Out of 257 Differentials that fit 2001 GMC Sierra 2500 HDs, the following parts are the top sellers:

Taper Bearing Cone (5051614) – $15.49
Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket (5723531) – $8.29
Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket (3215601) – $8.99

What’s the price range for 2001 GMC Sierra 2500 HD Differentials?

The prices of Differentials for the 2001 GMC Sierra 2500 HD range from $2.99 up to $4,070.00 for the most premium parts.

What is the average price of a Differential for a 2001 GMC Sierra 2500 HD?

The average price for Differentials for the 2001 GMC Sierra 2500 HD is $489.22. Keep in mind the variety of part types within our Differential category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Differentials for other GMC Sierra 2500 HD model years?

Yes, we carry Differentials for 24 model years of GMC Sierra 2500 HDs between 2002 and 2026. The following model years are the most popular for Differential purchases: 2023, 2022, 2021, 2020, 2019, 2018, 2017, 2016, and 2015.

What are the cheapest Differentials for my 2001 GMC Sierra 2500 HD?

The cheapest 2001 GMC Sierra 2500 HD Differentials we carry are:

Differential Crush Sleeve (20520169) – $2.99
Differential Cover Gasket (10282461) – $3.99
Differential Crush Sleeve (10593146) – $3.99
DiffrlPinSupportBolt (12018054) – $5.99
Differential Cover B (11777896) – $5.99

Does Advance Auto Parts sell Differentials for any other 2001 GMC models?

Yes. We stock Differentials for 19 other popular 2001 GMC models. Some of the most popular are 2001 Yukon Differentials, 2001 Sierra 1500 Differentials, 2001 Yukon XL 1500 Differentials, 2001 Yukon XL 2500 Differentials, and 2001 Savana 1500 Differentials.

What types of Differentials do you sell for my 2001 GMC Sierra 2500 HD?

As of 3/1/26, these are some of the most in-demand types of Differentials for a 2001 GMC Sierra 2500 HD:

Can I get help with 2001 GMC Sierra 2500 HD Differential orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about GMC Differentials and more.

What is your return policy for GMC Sierra 2500 HD Differentials?

Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2001 GMC Sierra 2500 HD Differentials

Yukon Gear – 3 Qt – Penzoil 80W90 Conventional Gear Oil (Part No.15002)

Motive Gear – Differential Carrier (Part No.6258336)

Dorman – Help – Differential Shaft Lock Bolt (Part No.81048)

Yukon Gear – Grizzly Locker For GM & Chrysler 11.5" With 38 Spline Axles (Part No.28014)

Yukon Gear – DiffrlPinSupportBolt (Part No.33582)

Yukon Gear – 11.5" GM & Chrysler Crush Sleeve (Part No.33098)

Pro-King – Differential Cover Gasket (Part No.743B303)

Yukon Gear – Cross Pin Shaft For GM 9.5", Fits Standard & Dura Grip Or Eaton Posi Carrier (Part No.33205)

Yukon Gear – 11.5" Chrysler & GM Helical Gear Type Positraction (Part No.32244)

Yukon Gear – Pinion Install Kit For ’99 & Newer 10.5" GM 14 Bolt Truck Differential (Part No.13106)

Yukon Gear – 10.5" & 11.5" GM & Dodge Pinion Seal (Part No.30281)

Powertrax – Lock Right Locker (Part No.1950-LR)

Yukon Gear – Steel Spool For GM 14 Bolt Truck With 30 Spline Axles, 4.10 & Down (Part No.32048)

Dorman – Differential Pinion Yoke Assembly (Part No.697-551)

Yukon Gear – GM 9.25" IFS Side Adjuster, ’11 & Up (Part No.33358)

Dorman – Differential Ring and Pinion Set (Part No.697-323)

Yukon Gear – Spider Gear Set For GM 9.5" Gura Drip Posi (Part No.16166)

Felpro – Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket (Part No.RDS 55063)

Dorman – Differential Cover (Part No.697-703)

Yukon Gear – 11.5" GM Standard Open Side Gear Thrust Washer (Part No.33387)

Yukon Gear – 11.5" GM & Chrysler Pinion Nut (Part No.33151)

Yukon Gear – Differential Cover B (Part No.33572)

Yukon Gear – Super Carrier Shim Kit For GM 9.5" (Part No.55003)

National – Bearing Race (Part No.HM903210)

Yukon Gear – Adjuster Lock Bolt For Left Hand Case Half Of 7.2" And 9.25" GM IFS (Part No.33244)

Dorman – Axle Shaft (Part No.630-148)

USA Standard Gear – Master Overhaul Kit for the ’10 & Down GM 9.25" IFS Front Differential (Part No.37061)

USA Standard Gear – Master Overhaul Kit for 2010 & Down GM & Chrysler 11.5" AAM Differential (Part No.37041)

National – Bearing Race (Part No.382A)

Driveworks – Taper Bearing Cone (Part No.S-LM-102949)

National – Tapered Roller Bearing Cone (Part No.28580)

Schaeffler – Cup (Part No.382A)

Dorman – Differential Cover (Part No.697-711)

Dorman – Differential Cover (Part No.697-712)

Dorman – Differential Cover (Part No.697-703)

Yukon Gear – Steel Cover For Chrysler & GM 11.5", With O Fill Plug (Part No.32330)

Yukon Gear – Finned Aluminum Cover For Dodge & GM 11.5" Aam Rear Axle (Part No.32346)

Yukon Gear – Steel Cover For GM 10.5" 14 Bolt Truck (Part No.32345)

Yukon Gear – Chrome Cover For 10.5" GM 14 Bolt Truck (Part No.32013)

ATP – DIFF COVER KIT (Part No.111104)

B & M – Hi-Tek Aluminum Differential Cover for AAM 11.5 – Black (Part No.11317)

aFe POWER – Differential Cover (Part No.46-71060B)

aFe POWER – Differential Cover (Part No.46-70372)

aFe POWER – Differential Cover (Part No.46-70370)

Felpro – Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket (Part No.RDS 55387)

Yukon Gear – 11.5" Chrysler & GM Cover Gasket (Part No.23013)

Yukon Gear – GM 10.5′ 14 Bolt Truck Cover Gasket (Part No.23016)

Pro-King – Differential Cover Gasket (Part No.743B303)

Felpro – Axle Housing Cover Gasket Irregular Shaped 14 Bolt Hole Gasket (Part No.RDS 55478)

Felpro – Axle Housing Cover Gasket: Irregular Shaped 14 Bolt Hole Gasket (Part No.RDS 55063)

Valvoline – MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.773775)

Yukon Gear – 3 Qt – 80W90 Conventional Gear Oil With Posi Additive (Part No.15003)

Yukon Gear – 3 Qt – Penzoil 80W90 Conventional Gear Oil (Part No.15002)

Yukon Gear – Redline Synthetic "Shock Proof" Oil With Positraction Additive – 4 Quarts (Part No.15005)

Yukon Gear – Redline Synthetic "Shock Proof" Oil – 3 Quarts (Part No.15000)

Yukon Gear – Redline Synthetic "Shock Proof" Oil – 4 Quarts (Part No.15004)

Castrol – Transmax ATF/CVT Universal Transmission Fluid, Smooth Performance, 1 Gallon (Part No.15E0C8)