2001 GMC C6500 Topkick Fuel and Emissions Systems

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Essential Fuel and Emissions Systems for 2001 GMC C6500 Topkicks

Carquest Premium – Fuel Pump Strainer (Part No.FS260354)

Fuel Pump Strainer

from

$9.99
CARQUEST Premium electric fuel pumps are built to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our CARQUEST Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. CARQUEST Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
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Carquest Premium – Multi-Use Connector (Part No.PTA1761)

Multi-Use Connector

from

$59.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Carquest Premium – Multi-Use Connector (Part No.PTA1107)

Multi-Use Connector

from

$29.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • WVE electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Delphi – Fuel Injector (Part No.EX634762)

Fuel Injector

from

$724.99
Delphi knows OE technology and how to service diesel systems. For more than 60 years, we have partnered with 25 OEM’s to bring our OE diesel powertrain knowledge and expertise to the aftermarket. Delphi diesel systems operate at high performance to meet today’s tough emissions standards and are built to OE specifications for the fit, form, and function technicians expect. Trust Delphi for an unrivalled, cost-effective diesel program to help build your business.

Product Features:
  • 100% O Ring replacement
  • All Delphi injectors are tested utilizing OE methodologies
  • Delphi injectors are produced in a Delphi ISO 9001:2008 certified facility
  • No internal seal rings equals minimized leakage
  • Recessed fuel exit minimizing possible plugging
  • Reduced spray variation, accurate fuel spray pattern mean better emissions and cold start capabilities
  • Thermally isolates fuel from engine by drawing manifold heat away from the fuel rail eliminating engine hesitation due to vapor lock
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Dorman – Fuel Tank Strap (Part No.578-434)

Fuel Tank Strap

from

$413.99
Recommended for replacement whenever the fuel tank is replaced or serviced, this strap is a direct replacement for the original. Manufactured from durable materials to withstand harsh road and weather conditions.

Product Features:
  • Direct replacement – this fuel tank strap matches the fit, function and performance of the original part
  • Ideal solution – recommended for replacement when the fuel tank is serviced or replaced
  • Durable construction – manufactured from quality materials for superior service and reliability
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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Carquest Premium – Fuel Pump Pulsator (Part No.A3541776)

Fuel Pump Pulsator

from

$25.99
CARQUEST Premium electric fuel pumps are built to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our CARQUEST Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. CARQUEST Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
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GM Genuine Parts – Fuel Injector Retainer Kit with Clip (Part No.12570620)

Fuel Injector Retainer Kit with Clip

from

$13.79
GM Genuine Parts Fuel Injector and Insulator Retainer Kits are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Multi-Port Fuel Injector O-Ring Kit with 16 O-Ring (Part No.217-1533)

Multi-Port Fuel Injector O-Ring Kit with 16 O-Ring

from

$31.99
GM Genuine Parts Fuel Injector Seal Kits are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help provide liquid-tight connections between the fuel injector and related components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps provide a seal to prevent fuel leaks
  • Helps seal combustion chamber from the elements
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Fuel Injection Pressure Regulator Kit with Clip and Snap Ring (Part No.217-3073)

Fuel Injection Pressure Regulator Kit with Clip and Snap Ring

from

$112.99
ACDelco GM Original Equipment Fuel Injection Pressure Regulators are mechanical valves that control fuel pressure in the fuel injector rail, and are GM-recommended replacements for your vehicle’s original components. Their spring-loaded valves return excess fuel back to the fuel tank. These original equipment fuel injection pressure regulators have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Helps provide constant fuel pressure to the injectors
  • Assists in cold engine starts
  • Helps maintain stable engine idle
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest Premium – Fuel Pump: Includes Wiring Harness (Part No.E219652)

Fuel Pump: Includes Wiring Harness

from

$72.99
Carquest Premium electric fuel pumps are engineered by Carter Fuel Systems or Agility Auto Parts to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our Carquest Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. Carquest Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
See More

Carquest Premium – Multi-Use Connector (Part No.PTA1252)

Multi-Use Connector

from

$35.49
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • WVE electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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GM Genuine Parts – Multi-Purpose Fuel Line O-Ring (Part No.19258137)

Multi-Purpose Fuel Line O-Ring

from

$3.99
GM Genuine Parts Multi Purpose Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – 2-Way Female Black Multi-Purpose Pigtail (Part No.PT288)

2-Way Female Black Multi-Purpose Pigtail

from

$59.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest Premium – New Mass Air Flow Sensor – Complete Assembly (Part No.MQ7202)

New Mass Air Flow Sensor - Complete Assembly

from

$92.99
Carquest Premium mass air flow (MAF) sensors are built to meet the original equipment (OE) specifications for each application. Our MAF sensors are built by a manufacturer that meets IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium mass air flow sensors are 100% new and undergo extensive validation testing to ensure long-lasting performance and reliability.

Product Features:
  • Designed to meet OE specifications for fit, form and function
  • 100% new unit with no core charge
  • Advanced micro-controlled technology delivers more accurate output in extreme temperatures
  • Extensive validation testing to ensure precision output for better performance and reliability
  • O-rings or gaskets included where applicable
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GM Genuine Parts – 3-Way Female Black Multi-Purpose Pigtail (Part No.PT420)

3-Way Female Black Multi-Purpose Pigtail

from

$41.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Manifold Absolute Pressure (MAP) Sensor (Part No.213-1545)

Manifold Absolute Pressure (MAP) Sensor

from

$85.99
ACDelco GM Original Equipment Manifold Absolute Pressure Sensors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.

Product Features:
  • This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
  • Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional
  • ACDelco GM Original Equipment parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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NTK – Air Charge Temperature Sensor (Part No.AJ0003)

Air Charge Temperature Sensor

from

$29.99
Building upon a foundation of premium full-line products established under NGK ignition and oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. is the only OE supplier with a full line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:
  • The Air Charge Temperature Sensor is used by the Engine Control Unit (ECU) to measure air density for fuel mixture control, which allows it to make continuous adjustments to the engine’s air or fuel mixture for maximum fuel efficiency.
  • NTK’s Air Charge Temperature Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function to ensure proper monitoring of air temperature entering the engine.
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Carquest Premium – Multi-Use Connector (Part No.PTA1142)

Multi-Use Connector

from

$46.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
See More

GM Genuine Parts – Multi-Purpose Relay (Part No.19118886)

Multi-Purpose Relay

from

$51.99
GM Genuine Parts Wiring Relays are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These relays help connect or disconnect power to a vehicle accessory when it receives a low voltage signal from a switch. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps connect or disconnect power to vehicle accessories
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Carquest Premium – EGR Valve (Part No.EGC1022)

EGR Valve

from

$146.99
Carquest Premium exhaust gas recirculation (EGR) valves are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Our Carquest Premium EGR valves are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium EGR valves undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium EGR valves are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • Precision engineering and robust design to withstand harsh under hood environment
  • Gaskets or seals are included if required for installation
  • Extensive design validation testing and 100% end-of-line tested
  • Where applicable stainless-steel sleeves used over cold rolled sleeves providing smooth EGR pintle operation under all operating conditions.
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Carquest Premium – Wiring Harness (Part No.WH3000)

Wiring Harness

from

$17.99
Carquest wiring harnesses are designed to replace worn, damaged, or corroded electrical connections, delivering reliable performance and long life.

Product Features:
  • Provides worry-free electrical performance
  • Designed to meet or exceed OE specifications
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Dorman – Body Bolt with Washer – M6-1.0 X 25mm (sold by each) (Part No.700-251)

Body Bolt with Washer - M6-1.0 X 25mm (sold by each)

from

$1.49
These nuts are manufactured using durable materials and corrosion tested to ensure required strength and Longevity.

Product Features:
  • Durable materials – manufactured to specific thread tolerance standards
  • Corrosion tested – hardware undergoes salt spray testing to ensure corrosion resistance
  • Multipurpose usefulness – can be used in a variety of applications, from auto to home
  • Trustworthy quality – backed by team of professional engineers and quality control specialists in the United States
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Felpro – Exhaust Gas Recirculation (EGR) Valve Gasket (Part No.70978)

Exhaust Gas Recirculation (EGR) Valve Gasket

from

$3.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered for the sealing repair environment
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
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Felpro – Exhaust Gas Recirculation (EGR) Valve Gasket (Part No.70783)

Exhaust Gas Recirculation (EGR) Valve Gasket

from

$4.29
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered for the sealing repair environment
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
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GM Genuine Parts – Fuel Tank Sending Unit Lock Ring (Part No.TR11)

Fuel Tank Sending Unit Lock Ring

from

$9.99
GM Genuine Parts Fuel Tank Lock Rings are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

GM Genuine Parts – Fuel Tank Sending Unit Lock Ring (Part No.TR9)

Fuel Tank Sending Unit Lock Ring

from

$18.99
GM Genuine Parts Fuel Tank Lock Rings are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Carquest Premium – Multi-Use Connector (Part No.PTA1096)

Multi-Use Connector

from

$44.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • WVE electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
See More

Upgrade your 2001 GMC C6500 Topkick with Top-Quality Fuel and Emissions Systems

When it comes to maintaining or upgrading your 2001 GMC C6500 Topkick, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Fuel and Emissions Systems are key to keeping your C6500 Topkick functioning at its best. At Advance Auto Parts, we offer a wide selection of 30 Fuel and Emissions Systems for the 2001 GMC C6500 Topkick, designed to meet your needs without breaking the bank. From Fuel Pump replacements to Oxygen Sensors upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Fuel and Emissions Systems for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Fuel and Emissions Systems for your 2001 GMC C6500 Topkick at great prices. Our Fuel and Emissions Systems inventory for this model ranges from just $1.49 to $413.99, with an average price of $72.22. Our 30 Fuel and Emissions Systems in stock come from 8 trusted brands, so you’re sure to find the right part for your 2001 GMC C6500 Topkick without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2001 GMC C6500 Topkick, we stock popular OEM and aftermarket Fuel and Emissions Systems from top names like Felpro, GM Genuine, Carquest Premium, and more. Felpro Fuel and Emissions Systems start at just $4.29 and boast an impressive 4.6 stars average rating from customers. GM Genuine and Carquest Premium also bring quality to the table, with Fuel and Emissions Systems available starting at $29.99, and at an average 4.5 stars rating. With 28 customer reviews and counting, our 2001 GMC C6500 Topkick Fuel and Emissions Systems have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Fuel and Emissions System upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2001 GMC C6500 Topkick is always ready to roll. We’re committed to providing you with everything you need to keep your C6500 Topkick in top shape, all in one place. Start shopping confidently below for your 2001 GMC C6500 Topkick!

Best-Selling Fuel Pumps for 2001 GMC C6500 Topkicks

Enhance the driving experience in your GMC with 6 quality Fuel Pump components, starting at $9.99.

Carquest Premium – Wiring Harness (Part No.WH3000)

Wiring Harness

from

$17.99
Carquest wiring harnesses are designed to replace worn, damaged, or corroded electrical connections, delivering reliable performance and long life.

Product Features:
  • Provides worry-free electrical performance
  • Designed to meet or exceed OE specifications
See More

Delphi – Electric Fuel Pump: Hose Clips, Hose Piece, Insulating Sleeve, Isolator, Seals (Part No.FE0114)

Electric Fuel Pump: Hose Clips, Hose Piece, Insulating Sleeve, Isolator, Seals

from

$124.99
Delphi is a Tier 1 supplier to the majority of global vehicle manufacturers and has been a manufacturer of dependable fuel pumps and fuel delivery parts for over 80 years. With over 30 OE-proprietary innovations and 150 patents in fuel technologies, Delphi is regarded as a market leader in North American fuel management with sales coverage at over 95%. Learn more about our expert-led training programs and tech hotline at 1-877-463-3574. Visit our Resource Center for helpful tips and tricks on fuel pumps, technologies, and more: https://www.delphiautoparts.com/usa/en-US/resource-center.

Product Features:
  • Delphi is a global OE manufacturer and all fuel pumps are built to Delphi’s OE standards
  • Delphi pumps are designed to operate under extreme temperatures with quick engine starts
  • Improved pump performance as a result of Delphi’s innovative design and durability
  • Restores fast pressure performance and system integrity, translating to better pumping through less energy
  • Part is validated, tested and matched to the right vehicle application
  • Lower amperage draws less load on vehicle’s electrical system
  • Always be sure to check and clean fuel tank to avoid unnecessary returns
  • Always replace the fuel strainer when doing a fuel pump repair
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Carquest Premium – Fuel Pump: Includes Wiring Harness (Part No.E219657)

Fuel Pump: Includes Wiring Harness

from

$48.99
Carquest Premium electric fuel pumps are engineered by Carter Fuel Systems or Agility Auto Parts to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our Carquest Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. Carquest Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
See More

Carquest Premium – Fuel Pump Strainer (Part No.FS260354)

Fuel Pump Strainer

from

$9.99
CARQUEST Premium electric fuel pumps are built to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our CARQUEST Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. CARQUEST Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
See More

Carquest Premium – Fuel Pump: Includes Strainer (Part No.E2541177)

Fuel Pump: Includes Strainer

from

$134.99
Carquest Premium electric fuel pumps are engineered by Carter Fuel Systems or Agility Auto Parts to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our Carquest Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. Carquest Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
See More

Carquest Premium – Fuel Pump Pulsator (Part No.A3541776)

Fuel Pump Pulsator

from

$25.99
CARQUEST Premium electric fuel pumps are built to meet or exceed Original Equipment (OE) specifications for fit, form and function. Our CARQUEST Premium fuel pumps are built to be installed in the Original Equipment module or assembly. We have invested in industry-leading quality upgrades, like upgraded turbine impellers and 100% carbon commutators, to deliver greater reliability. CARQUEST Premium electric fuel pumps are engineered with superior quality components to provide the longest life and reliable performance.

Product Features:
  • Meets or exceeds OE specifications for fit, form and function
  • 100% carbon commutators provide resistance to aggressive fuels and double the life expectancy of the pump
  • OE upgraded turbine impellers greatly reduce fuel pulsation
  • All fuel pumps are 100% performance tested
See More

Most Popular 2001 GMC C6500 Topkick Oxygen Sensors

Customize your GMC with 1 Oxygen Sensors products like Oxygen Sensor Connectors, all priced under $43.99.

Carquest Premium – Multi-Use Connector (Part No.PTA3163)

Multi-Use Connector

from

$43.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
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Top Picks for 2001 GMC C6500 Topkick Air Flow Sensors

Upgrade GMC C6500 Topkicks with top-quality Air Flow Sensors parts, including 4 OEM and aftermarket selections for your 2001 model.

NTK – Manifold Absolute Pressure Sensor (Part No.MA0097)

Manifold Absolute Pressure Sensor

from

$81.99
Building upon a foundation of premium full-line products established under NGK ignition and oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. is the only OE supplier with a full line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:
  • The Manifold Absolute Pressure Sensor (MAP) provides manifold pressure information to the Engine Control Unit (ECU). The data is used to determine the air mass flow rate and required fuel for optimum combustion and ignition timing.
  • NTK’s Manifold Absolute Pressure Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function to ensure proper manifold pressure, fuel metering and ignition timing.
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NTK – Air Charge Temperature Sensor (Part No.AJ0003)

Air Charge Temperature Sensor

from

$29.99
Building upon a foundation of premium full-line products established under NGK ignition and oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. is the only OE supplier with a full line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:
  • The Air Charge Temperature Sensor is used by the Engine Control Unit (ECU) to measure air density for fuel mixture control, which allows it to make continuous adjustments to the engine’s air or fuel mixture for maximum fuel efficiency.
  • NTK’s Air Charge Temperature Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function to ensure proper monitoring of air temperature entering the engine.
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Dorman – Body Bolt with Washer – M6-1.0 X 25mm (sold by each) (Part No.700-251)

Body Bolt with Washer - M6-1.0 X 25mm (sold by each)

from

$1.49
These nuts are manufactured using durable materials and corrosion tested to ensure required strength and Longevity.

Product Features:
  • Durable materials – manufactured to specific thread tolerance standards
  • Corrosion tested – hardware undergoes salt spray testing to ensure corrosion resistance
  • Multipurpose usefulness – can be used in a variety of applications, from auto to home
  • Trustworthy quality – backed by team of professional engineers and quality control specialists in the United States
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Carquest Premium – Multi-Use Connector (Part No.PTA1107)

Multi-Use Connector

from

$29.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • WVE electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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In-Demand Fuel Injectors for 2001 GMC C6500 Topkicks

Select from 7 premium Fuel Injectors parts for your 2001 GMC C6500 Topkick, with prices ranging from $13.79 to $139.99.

GM Genuine Parts – Fuel Injector O-Ring Kit with Assorted O-Rings (Part No.217-1588)

Fuel Injector O-Ring Kit with Assorted O-Rings

from

$29.99
GM Genuine Parts Fuel Injector Seal Kits are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help provide liquid-tight connections between the fuel injector and related components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps provide a seal to prevent fuel leaks
  • Helps seal combustion chamber from the elements
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – New Mass Air Flow Sensor – Complete Assembly (Part No.MQ7202)

New Mass Air Flow Sensor - Complete Assembly

from

$92.99
Carquest Premium mass air flow (MAF) sensors are built to meet the original equipment (OE) specifications for each application. Our MAF sensors are built by a manufacturer that meets IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium mass air flow sensors are 100% new and undergo extensive validation testing to ensure long-lasting performance and reliability.

Product Features:
  • Designed to meet OE specifications for fit, form and function
  • 100% new unit with no core charge
  • Advanced micro-controlled technology delivers more accurate output in extreme temperatures
  • Extensive validation testing to ensure precision output for better performance and reliability
  • O-rings or gaskets included where applicable
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GM Genuine Parts – Fuel Injection Pressure Regulator Kit with Clip and Snap Ring (Part No.217-3073)

Fuel Injection Pressure Regulator Kit with Clip and Snap Ring

from

$112.99
ACDelco GM Original Equipment Fuel Injection Pressure Regulators are mechanical valves that control fuel pressure in the fuel injector rail, and are GM-recommended replacements for your vehicle’s original components. Their spring-loaded valves return excess fuel back to the fuel tank. These original equipment fuel injection pressure regulators have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Helps provide constant fuel pressure to the injectors
  • Assists in cold engine starts
  • Helps maintain stable engine idle
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Wells Vehicle Electronics – Fuel Injection Pressure Regulator (Part No.5G1070)

Fuel Injection Pressure Regulator

from

$94.99
WVE is a leading source of advanced vehicle electronics components for replacement applications in the automotive aftermarket and original equipment applications. WVE offers high-technology manufacturing along with innovative solutions and improvements to OE designs. Every component either matches or improves on the OE design to ensure fast, easy installation, superior performance and reliability.

Product Features:
  • Application matched components ensure fuel injection system meets all emission regulations.
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
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Carquest Premium – Multi-Use Connector (Part No.PTA1096)

Multi-Use Connector

from

$44.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • WVE electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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GM Genuine Parts – Fuel Injector Retainer Kit with Clip (Part No.12570620)

Fuel Injector Retainer Kit with Clip

from

$13.79
GM Genuine Parts Fuel Injector and Insulator Retainer Kits are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Delphi – Fuel Injector (Part No.FJ10494)

Fuel Injector

from

$139.99
Delphi’s history is one of OE heritage and quality. Our global technical requirements include design specifications and validation testing based on over 100 years of OE experience. Our material selections, material thickness, and material types are built from OE specifications to exceed aftermarket expectations. We put in place strict manufacturing processes to ensure quality control in every part we make. Delphi’s pioneering spirit delivers innovative solutions designed to support the aftermarket in servicing the vehicles of today, and tomorrow.

Product Features:
  • 100% O Ring replacement
  • All Delphi injectors are tested utilizing OE methodologies
  • Delphi injectors are produced in a Delphi ISO 9001:2008 certified facility
  • No internal seal rings equals minimized leakage
  • Recessed fuel exit minimizing possible plugging
  • Reduced spray variation, accurate fuel spray pattern mean better emissions and cold start capabilities
  • Thermally isolates fuel from engine by drawing manifold heat away from the fuel rail eliminating engine hesitation due to vapor lock
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Most Sold 2001 GMC C6500 Topkick Fuel Tanks

Explore our best-selling GMC parts for the 2001 C6500 Topkick among 3 OEM and aftermarket options starting from $9.99.

Carquest Premium – Fuel Tank Lock Ring (Part No.LO1582929)

Fuel Tank Lock Ring

from

$16.99
Carquest Premium fuel tank lock rings are built by Carter Fuel Systems and Agility Auto Parts, industry leaders in high-quality fuel system components. Carquest Premium offers a complete line of fuel tank lock rings covering a wide variety of North American vehicle applications. Carquest Premium fuel tank lock rings are engineered to meet or exceed all OEM specifications. Carquest Premium fuel tank lock rings are precision stamped and are treated with a rust proof finish to ensure durability and strength.

Product Features:
  • Engineered to meet or exceed all OEM specifications.
  • Precision stamped and are treated with a rust proof finish to ensure durability and strength.
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Dorman – Fuel Tank Strap (Part No.578-434)

Fuel Tank Strap

from

$413.99
Recommended for replacement whenever the fuel tank is replaced or serviced, this strap is a direct replacement for the original. Manufactured from durable materials to withstand harsh road and weather conditions.

Product Features:
  • Direct replacement – this fuel tank strap matches the fit, function and performance of the original part
  • Ideal solution – recommended for replacement when the fuel tank is serviced or replaced
  • Durable construction – manufactured from quality materials for superior service and reliability
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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GM Genuine Parts – Fuel Tank Sending Unit Lock Ring (Part No.TR11)

Fuel Tank Sending Unit Lock Ring

from

$9.99
GM Genuine Parts Fuel Tank Lock Rings are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Top-Rated Fuel and Emissions Systems Brands For Your 2001 GMC C6500 Topkick

Shop for the best-rated brands offering Fuel and Emissions Systems and other products for your 2001 GMC C6500 Topkicks. Below you’ll find some of our best rated Fuel and Emissions Systems from Felpro, GM Genuine, and Carquest Premium, and more. Fuel and Emissions Systems from these brands that fit a 2001 C6500 Topkick start at just $4.29 and are rated as high as 4.6 stars. OEM and aftermarket Fuel and Emissions Systems don’t get more top quality, durable, and affordable than from the brands below.

Popular Felpro 2001 GMC C6500 Topkick Fuel and Emissions Systems

When it comes to maintaining or upgrading your 2001 GMC C6500 Topkick, using quality Fuel and Emissions Systems is essential to ensure durability and a perfect fit. Felpro ticks all of those boxes. We offer a wide selection of Felpro Fuel and Emissions Systems, specifically designed for the 2001 GMC C6500 Topkick. With over 1 Felpro brand Fuel and Emissions Systems in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $4.29. Plus, with over 4 customer reviews and an average rating of 4.6 stars, you can trust that our Felpro Fuel and Emissions Systems will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
Exhaust Gas Recirculation (EGR) Valve Gasket
from $4.29
(4)
Exhaust Gas Recirculation (EGR) Valve Gasket
“Fits perfect”

Popular GM Genuine 2001 GMC C6500 Topkick Fuel and Emissions Systems

GM Genuine auto parts is one of the highest quality Fuel and Emissions System brands in the market. Any 2001 GMC C6500 Topkick owner should feel confident when installing genuine GM Genuine parts in their vehicle. To ensure the best fit and performance for your 2001 C6500 Topkick, Advance Auto Parts carries a full inventory of 1 GM Genuine Fuel and Emissions Systems. Plus you will be keeping your GMC in peak condition while saving money because prices on these GM Genuine Fuel and Emissions Systems range up to $29.99, plus, with more than 1 customer reviews and an impressive 4.5 stars average rating, you can be confident the Fram Fuel and Emissions Systems below will deliver on both quality and value.
Fuel Injector O-Ring Kit with Assorted O-Rings
from $29.99
(1)
Fuel Injector O-Ring Kit with Assorted O-Rings
“Exactly what my son needed!! Awesome FREE home delivery option via DoorDash!!”

FAQs for 2001 GMC C6500 Topkick Fuel and Emissions Systems

Which Fuel and Emissions Systems are best-sellers for 2001 GMC C6500 Topkicks?

Out of 30 Fuel and Emissions Systems that fit 2001 GMC C6500 Topkicks, the following parts are the top sellers:

What’s the price range for 2001 GMC C6500 Topkick Fuel and Emissions Systems?

Fuel and Emissions System prices for the 2001 GMC C6500 Topkick start at $1.49 and go up to $413.99 for the most premium parts.

What’s the average price of a Fuel and Emissions System for a 2001 GMC C6500 Topkick?

The average price for Fuel and Emissions Systems for the 2001 GMC C6500 Topkick is $72.22. Keep in mind the variety of part types within our Fuel and Emissions System category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Fuel and Emissions Systems for other GMC C6500 Topkick model years?

Yes, we currently carry Fuel and Emissions Systems for 11 model years of GMC C6500 Topkicks between 1997 and 2009. Fuel and Emissions Systems are bought most frequently for the following model years: 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2002, and 2000.

What are the cheapest Fuel and Emissions Systems for my 2001 GMC C6500 Topkick?

The cheapest 2001 GMC C6500 Topkick Fuel and Emissions Systems we carry in stock are:

What are the top-rated Fuel and Emissions Systems that fit the 2001 GMC C6500 Topkick?

Out of 28 reviews by customers, our 2001 GMC C6500 Topkick Fuel and Emissions Systems have an average customer rating of . These are some of the highest-rated Fuel and Emissions System types for the 2001 GMC C6500 Topkick and their top-rated products:

What types of Fuel and Emissions Systems do you sell for my 2001 GMC C6500 Topkick?

Can I get help with 2001 GMC C6500 Topkick Fuel and Emissions System orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Fuel and Emissions Systems and more.

What is your return policy for GMC C6500 Topkick Fuel and Emissions Systems?

Advance Auto Parts keeps returns simple. For new GMC C6500 Topkick Fuel and Emissions Systems and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.