Mercedes-Benz E350 Engine Cooling Parts

Your One-Stop Shop For Trusted Mercedes-Benz E350 Engine Cooling Parts

If you’re in search of Mercedes-Benz E350 Engine Cooling Parts aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 42 Engine Cooling Parts from top brands with prices ranging from $1.49 to $862.99.

Beyond great prices, we stock trusted brands manufacturing all types of Engine Cooling Parts for your Mercedes-Benz E350.

And don’t forget to read customer reviews across all Engine Cooling Parts categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Engine Cooling Parts have to cost top dollar, and we prove it. Browse our top Mercedes-Benz E350 Engine Cooling Parts below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Please Select your Vehicle to See Exact Fit Parts

Essential Mercedes-Benz E350 Engine Cooling Parts

Rein – Coolant Drain Plug (Part No.HWB0114)

Coolant Drain Plug

from

$11.99
Product Features:
  • Ensures proper function of engine cooling system.
  • Designed as direct-fit replacement to ensure trouble-free proper installations.
  • Manufactured to strict engineering standards and specifications in materials and tolerances.
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Motorad – Integrated Thermostat Housing: With Sensor, With Seal, 217 Degrees (Part No.785-217)

Integrated Thermostat Housing: With Sensor, With Seal, 217 Degrees

from

$262.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Rein – Cap-Expansion Tank (Part No.CPE0029P)

Cap-Expansion Tank

from

$32.99
Rein Automotive OE Quality expansion tank caps are designed to be direct replacements for OE caps. Rein caps are designed to match or exceed the OE materials used and are produced to the highest standards to ensure long service life. Rein Automotive OE quality expansion tank caps keep the coolant system at the proper pressure just like the OE cap.

Product Features:
  • Manufactured to strict engineering standards/specifications in materials and tolerances.
  • Direct fit.
  • Meets or exceeds pressure specifications demanded by the OE manufacturer.
  • Produced by an original equipment supplier.
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KAI – Radiator Support Tie Bar (Part No.MB1225144)

Radiator Support Tie Bar

from

$32.99
New Standard Replacement Radiator Support Upper Tie Bar, Sedan And Wagon, Made Of High Strength Steel

Product Features:
  • Sedan And Wagon, Made Of High Strength Steel
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Motorad – Integrated Thermostat Housing: With Sensor, Spring Clip, Seal, 212 Degrees (Part No.785-212)

Integrated Thermostat Housing: With Sensor, Spring Clip, Seal, 212 Degrees

from

$263.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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URO Parts – Thermostat Assembly w/o temp sensor (Part No.2762000515)

Thermostat Assembly w/o temp sensor

from

$73.99
For European vehicles, A.P.A. manufactures the URO Parts brand of quality replacement parts, which meet or exceed OEM specifications. URO Parts components are ideal for both professional and DIY vehicle repair, and are often the exclusive aftermarket alternative to overpriced ¿Genuine¿ components. By reducing deferred maintenance with URO Parts, you will increase the bottom line of your business. With its URO Premium line, A.P.A. offers problem-solving upgraded components that are superior to failure-prone OEM parts in design and/or materials. A.P.A. is so confident in the longevity and reliability of URO Premium products, . URO Parts also specializes in accurate reproduction parts for classic vehicles, including a huge variety of items that are no longer available from the dealer.

Product Features:
  • Guaranteed fitment
  • High-flow OE-style design for optimal engine cooling performance
  • Thermostat housing assembly is manufactured to factory housing dimensions for easy bolt-on installation and reliable hose connections
  • Includes temperature sensor where applicable
  • High-quality alloy or composite material is temperature-stable to resist warping or cracking that can lead to coolant leakage
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Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3128)

Engine Water Pump: New, Gasket/Seals Included

from

$204.99
This premium water pump uses new high-quality components and is designed to meet or exceed OE specifications. This pump is 100% tested to ensure quality. Bearings, gaskets, seals, impeller, hub and housing are all designed for long-lasting service life. All necessary gaskets and seals are included.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
  • Additional Notes: Includes gasket
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Dorman – Auxiliary Coolant Pump (Part No.902-065)

Auxiliary Coolant Pump

from

$215.99
This engine auxiliary water pump is designed to match the fit and function of the original pump on specified applications, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this engine auxiliary water pump is designed to match the fit and function of the original pump on specified applications
  • Restores functionality – reliable replacement for an original pump that has failed to provide sufficient water flow
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Radiator Fan Assembly: Single, with Controller, Cost Effective and Reliable (Part No.621-373)

Radiator Fan Assembly: Single, with Controller, Cost Effective and Reliable

from

$513.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
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KAI – Radiator (Part No.RAD2868)

Radiator

from

$169.99
New Platinum Pro Radiator, 3.2 And 3.5 Liter Engines, Without PZEV Emissions Package

Product Features:
  • 3.2 And 3.5 Liter Engines, Without PZEV Emissions Package, Made Of Plastic and Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Warranty: 5 Year, Limited
  • Radiator Cap Not Included
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – Radiator (Part No.813162)

Radiator

from

$276.99
Carquest Premium Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Carquest Premium Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.

Product Features:
  • Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
  • Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
  • Our fin edges are folded for increased stability and heat disbursement properties.
  • Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
  • Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
  • We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
  • We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
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MAHLE Original – Engine Coolant Thermostat Gasket (Part No.C31964)

Engine Coolant Thermostat Gasket

from

$1.49
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
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Victor Reinz – Engine Coolant Thermostat Gasket (Part No.41-76159-00)

Engine Coolant Thermostat Gasket

from

$18.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Felpro – Engine Coolant Thermostat Housing Gasket (Part No.36241)

Engine Coolant Thermostat Housing Gasket

from

$3.79
Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered for the sealing repair environment
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
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MAHLE Original – Engine Coolant Thermostat Housing Gasket (Part No.C31967)

Engine Coolant Thermostat Housing Gasket

from

$3.99
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

URO Parts – EAC Temperature Sensor (Part No.221905560080)

EAC Temperature Sensor

from

$119.99
For European vehicles, A.P.A. manufactures the URO Parts brand of quality replacement parts, which meet or exceed OEM specifications. URO Parts components are ideal for both professional and DIY vehicle repair, and are often the exclusive aftermarket alternative to overpriced ¿Genuine¿ components. By reducing deferred maintenance with URO Parts, you will increase the bottom line of your business. With its URO Premium line, A.P.A. offers problem-solving upgraded components that are superior to failure-prone OEM parts in design and/or materials. A.P.A. is so confident in the longevity and reliability of URO Premium products, . URO Parts also specializes in accurate reproduction parts for classic vehicles, including a huge variety of items that are no longer available from the dealer.

Product Features:
  • Guaranteed fitment
  • Direct-fit OE replacement design restores proper factory cooling fan sensor function
  • Easy plug-and-play connection
  • Manufactured using high-quality materials to withstand intense engine compartment and cooling system heat
  • Alloy conductors minimize electrical resistance for accurate operation
  • Designed and tested for reliability and long life
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Carquest Premium – Coolant Temperature Sensor 1TS1049 (Part No.WTC1122)

Coolant Temperature Sensor 1TS1049

from

$21.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
  • O-rings, seals or thread sealant are included if required
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Felpro – Engine Water Pump Gasket (Part No.36220)

Engine Water Pump Gasket

from

$14.99
Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered for the sealing repair environment
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
See More

Victor Reinz – Engine Water Pump Gasket (Part No.71-37719-00)

Engine Water Pump Gasket

from

$7.79
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Rein – Radiator Mount (Part No.AVM0699)

Radiator Mount

from

$22.99
Anti-vibration parts dampen vibration harmonics from the engine and drive line components to rest of the vehicle. This in turn reduces vibration and noise which can be felt and heard while the vehicle is in operation. Rein Automotive anti-vibration parts are application specific and match the design and function of the OE parts.

Product Features:
  • Rubber components match the shore hardness of the original equipment bushing to ensure maximum performance and product longevity.
  • Part has a high corrosion resistance for maximum life.
  • Produced with high quality materials to ensure maximum life and a smooth ride.
  • Made by the OE manufacturer.
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Rein – RADIATOR MOUNT (Part No.AVM0738)

RADIATOR MOUNT

from

$4.99
Anti-vibration parts dampen vibration harmonics from the engine and drive line components to rest of the vehicle. This in turn reduces vibration and noise which can be felt and heard while the vehicle is in operation. Rein Automotive anti-vibration parts are application specific and match the design and function of the OE parts.

Product Features:
  • Rubber components match the shore hardness of the original equipment bushing to ensure maximum performance and product longevity.
  • Part has a high corrosion resistance for maximum life.
  • Produced with high quality materials to ensure maximum life and a smooth ride.
  • Made by the OE manufacturer.
See More

Dorman – Radiator Fan Assembly (Part No.620-937)

Radiator Fan Assembly

from

$862.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
See More

URO Parts – Expansion Tank (Part No.2045000749)

Expansion Tank

from

$23.99
For European vehicles, A.P.A. manufactures the URO Parts brand of quality replacement parts, which meet or exceed OEM specifications. URO Parts components are ideal for both professional and DIY vehicle repair, and are often the exclusive aftermarket alternative to overpriced ¿Genuine¿ components. By reducing deferred maintenance with URO Parts, you will increase the bottom line of your business. With its URO Premium line, A.P.A. offers problem-solving upgraded components that are superior to failure-prone OEM parts in design and/or materials. A.P.A. is so confident in the longevity and reliability of URO Premium products, . URO Parts also specializes in accurate reproduction parts for classic vehicles, including a huge variety of items that are no longer available from the dealer.

Product Features:
  • Guaranteed fitment
  • Precision-molded to OE dimensions to ensure compatibility with original sensors and connections
  • Quality materials resist engine heat and harsh cooling system environment
  • Factory pressure-tested
See More

Rein – Expansion Tank (Part No.EPT0132)

Expansion Tank

from

$63.99
Rein Automotive OE quality expansion tanks, install, fit and perform the way the original manufacturer intended. These tanks are designed to match or exceed the OE materials used and are produced from virgin plastic with no regrind to prevent cracking from heat cycles and ensure the plastic is durable and will have a long service life.

Product Features:
  • Produced from virgin plastic meeting/exceeding OE specifications and ensuring long life
  • Resistant to cracking and wear from heat cycles preventing coolant loss
  • Direct fitment allows easy installation
  • Manufactured to strict engineering standards/specifications in materials and tolerances
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Dorman – Pressurized Coolant Reservoir: Black and Clear, Plastic, Original Equipment Replacement (Part No.603-257)

Pressurized Coolant Reservoir: Black and Clear, Plastic, Original Equipment Replacement

from

$65.99
This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part.

Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part
  • Ideal solution – engineered for a seamless installation
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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Engine Cooling Parts Brands You Can Trust For Your Mercedes-Benz E350

9 trusted brands of Engine Cooling Parts line our shelves, ready to help keep your Mercedes-Benz E350 running smooth. Below are some of the most popular brands and their top Engine Cooling Parts offerings:

Most Purchased Mercedes-Benz E350 Engine Cooling Parts from Motorad

When you buy the most frequently purchased Motorad brand Engine Cooling Parts, you can be confident it will be the right part for your Mercedes-Benz E350. Here are the Motorad Engine Cooling Parts Advanced Auto customers buy the most:
Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees
from $117.99
(6)
Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees
Thermostat and Water Outlet Assemblies
Radiator
from $249.99
(1)
Radiator
Radiators
Engine Water Pump: New, Gasket/Seals Included
from $204.99
This product is not rated
Engine Water Pump: New, Gasket/Seals Included
Water Pumps

FAQs for Mercedes-Benz E350 Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the Mercedes-Benz E350?

Out of 42 Engine Cooling Parts for the Mercedes-Benz E350, the most popular in our inventory are:
Standard Reservoir Cap: 21 PSI
from $19.99
(1)
Standard Reservoir Cap: 21 PSI
Coolant Reservoir Caps
Pressurized Coolant Reservoir: Black and White, Plastic, Original Equipment Replacement
from $72.99
This product is not rated
Pressurized Coolant Reservoir: Black and White, Plastic, Original Equipment Replacement
Coolant Reservoirs
Radiator
from $249.99
(1)
Radiator
Radiators

What are the top-rated Mercedes-Benz E350 Engine Cooling Parts?

Top-rated Engine Cooling Parts for your Mercedes-Benz E350 based on customer reviews/ratings are:
Engine Water Pump: New
from $265.99
(2)
Engine Water Pump: New
“Wonderful after market part for my mercedes Benz. Perfect fit. Very very reasonable price”