GMC Sierra 2500 HD Window Regulators

Your GMC Sierra 2500 HD will be happy to know that the search for the right Window Regulators you’ve been looking for is over! Advance Auto Parts has 29 different Window Regulators for your vehicle, ready for shipping or in-store pick up. The best part is, our GMC Sierra 2500 HD Window Regulators start from as little as $48.99.

When it comes to your GMC Sierra 2500 HD, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Window Regulators brands so you can shop with complete confidence. Some of our top Window Regulators brands are Dorman and GM Genuine Parts. We’re sure you will get the right product to keep that Sierra 2500 HD running for a long time.

We even have reviews of our OEM and aftermarket Window Regulators products to help you buy with confidence. Hear from other customers via the 6,731 reviews on parts for your GMC Sierra 2500 HD.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Window Regulators for your Sierra 2500 HD, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 25 GMC Window Regulators

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-690)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$95.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-388)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$75.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-691)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$95.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.748-229)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$127.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-389)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$76.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-014)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$108.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Front Driver Side Window Regulator: Manual, 1 Pack (Part No.740-651)

Front Driver Side Window Regulator: Manual, 1 Pack

from

$55.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-015)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$99.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-890)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$133.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator: Power, 1 Pack (Part No.740-014)

Window Regulator: Power, 1 Pack

from

$44.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator: Power, 1 Pack (Part No.740-691)

Window Regulator: Power, 1 Pack

from

$82.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.748-264)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$87.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-578)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$73.99
The original equipment window regulator fails when the cable binds because it has poor tension. This Dorman OE FIX replacement regulator incorporates cable tension springs to resist cable reel binding.

Product Features:
  • Improved replacement – this window regulator and motor assembly features enhancements over the original design for greater reliability
  • Failure-resistant design – features cable tension springs to resist cable reel binding from insufficient tension
  • Simple replacement – no special tools are required to install this regulator assembly
  • Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
See More

Dorman – Front Passenger Side Window Regulator: Power, 1 Pack (Part No.740-645)

Front Passenger Side Window Regulator: Power, 1 Pack

from

$58.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.748-228)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$117.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

ACDelco – Professional Power Window Regulator and Motor Assembly (Part No.O3052578120ACD)

Professional Power Window Regulator and Motor Assembly

from

$159.05
Use an ACDelco Professional Window Regulator to replace your worn equipment. With a full line of regulator and motor assemblies available, you can find the right part for many of today’s most popular cars, trucks and SUV’s.

Product Features:
  • Motors are direct fit with connectors provided
  • All Motors are new, not remanufactured
  • Designed and built to meet or exceed OE performance
See More

Dorman – Window Regulator: Power, 1 Pack (Part No.740-644)

Window Regulator: Power, 1 Pack

from

$48.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.741-892)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$164.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Front Passenger Side Window Regulator: Manual, 1 Pack (Part No.740-518)

Front Passenger Side Window Regulator: Manual, 1 Pack

from

$73.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models. Every Dorman part is backed by over 100 years of experience, along with a dedicated team of product experts, automotive engineers and technical support specialists based in the United States. We are passionate about giving repair professionals and vehicle owners greater freedom to fix cars and trucks, which is why we have more than 100,000 parts in our catalog today and promise to never stop driving new solutions.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Front Driver Side Window Regulator: Manual, 1 Pack (Part No.740-517)

Front Driver Side Window Regulator: Manual, 1 Pack

from

$68.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models. Every Dorman part is backed by over 100 years of experience, along with a dedicated team of product experts, automotive engineers and technical support specialists based in the United States. We are passionate about giving repair professionals and vehicle owners greater freedom to fix cars and trucks, which is why we have more than 100,000 parts in our catalog today and promise to never stop driving new solutions.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator: Power, 1 Pack (Part No.740-655)

Window Regulator: Power, 1 Pack

from

$45.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator & Motor Assembly: Power, 1 Pack (Part No.751-724)

Window Regulator & Motor Assembly: Power, 1 Pack

from

$151.99
This replacement power window motor and regulator assembly is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
  • Reliable design – engineered in North America and backed by long history of automotive aftermarket experience
See More

Dorman – Window Regulator: Manual, 1 Pack (Part No.749-260)

Window Regulator: Manual, 1 Pack

from

$36.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

Dorman – Window Regulator: Power, 1 Pack (Part No.740-515)

Window Regulator: Power, 1 Pack

from

$61.99
This replacement window regulator is precision-engineered and extensively tested to match the exact fit, function and performance of the stock window regulator on specific vehicle years, makes and models.

Product Features:
  • Trustworthy replacement – engineered and tested to match the fit, function and performance of the original window regulator on specified vehicles
  • Quality assured – extensively tested by cycling thousands of times in an actual vehicle door to ensure a long, trouble-free service life
  • Reliable design – engineered in the USA and backed by long history of automotive aftermarket experience
  • Easy installation – reverse-engineered to match the original equipment shape and dimensions to provide a direct, seamless fit
See More

GM Genuine Parts – Rear Power Sliding Window Regulator and Motor Assembly (Part No.25980205)

Rear Power Sliding Window Regulator and Motor Assembly

from

$158.99
GM Genuine Parts Power Sliding Window Regulators are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

FAQs for GMC Sierra 2500 HD Window Regulators

What are the most popular Window Regulators for the GMC Sierra 2500 HD?

With 7 brands you can trust, our most popular Window Regulators for the GMC Sierra 2500 HD are:
Window Regulator & Motor Assembly: Power, 1 Pack
from $73.99
(28)
Window Regulator & Motor Assembly: Power, 1 Pack
Window Regulators
Window Regulator: Power, 1 Pack
from $48.99
(15)
Window Regulator: Power, 1 Pack
Window Regulators
Window Regulator & Motor Assembly: Power, 1 Pack
from $75.99
(5)
Window Regulator & Motor Assembly: Power, 1 Pack
Window Regulators

What are the best aftermarket Window Regulators for the GMC Sierra 2500 HD?

See what past customers had to say about our highest-rated Window Regulators for the GMC Sierra 2500 HD:
Window Regulator & Motor Assembly: Power, 1 Pack
from $76.99
(5)
Window Regulator & Motor Assembly: Power, 1 Pack
“Looks like they improved the design from OEM (gone through 2 OEM already). Can’t beat the life time warrantee and fits my extended cab rear power wind”
Front Driver Side Window Regulator: Manual, 1 Pack
from $68.99
(2)
Front Driver Side Window Regulator: Manual, 1 Pack
“Passenger side fit great but had to return the driver side. Driver side appeared to be the same except instead of threaded mount holes it had threaded”
Front Passenger Side Window Regulator: Manual, 1 Pack
from $73.99
(1)
Front Passenger Side Window Regulator: Manual, 1 Pack
“Passenger side fit great but had to return the driver side. Driver side appeared to be the same except instead of threaded mount holes it had threaded”