GMC Sierra 2500 HD Ignition Wires

Your One-Stop Shop For Trusted GMC Sierra 2500 HD Ignition Wires

If you’re in search of GMC Sierra 2500 HD Ignition Wires aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 23 Ignition Wires from top brands with prices ranging from $60.29 to $271.27.

Beyond great prices, we stock trusted brands manufacturing all types of Ignition Wires for your GMC Sierra 2500 HD. Of the 9 OEM and aftermarket parts brands we carry, some of the most popular are Carquest Premium, ACDelco, and MSD Ignition.

And don’t forget to read customer reviews across all Ignition Wires categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Ignition Wires have to cost top dollar, and we prove it. Browse our top GMC Sierra 2500 HD Ignition Wires below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential GMC Sierra 2500 HD Ignition Wires

MSD Ignition – Wire Set; Super Conductor; LS-1 Truck Engines; 99 (Part No.32829)

Wire Set; Super Conductor; LS-1 Truck Engines; 99

from

$109.99
The MSD 8.5mm super conductor wire is the performance wire. Engineered from the inside out, the 8.5 offers everything you have ever wanted in a wire; incredibly low resistance without electronic interference. In a single 12 inch length of super conductor wire there is only 40 – 50 ohms of resistance. That is the lowest resistance of any helically wound wire. To accomplish this, we use a copper alloy conductor due to it’s great voltage carrying capabilities. The low resistance results in less loss in spark energy so more reaches the spark plug. The conductor is wound extremely tight around a special center core. So tight in fact, that there is over 40 feet of conductor wrapped into a single foot of plug wire. This winding procedure, combined with a ferro-magnetic impregnated center core, produces an extremely effective electro magnetic interference (EMI) or choke. This choke, or suppression capability, keeps the EMI inside the wire where it cannot interfere with other electronics on your vehicle. The outer sleeve that surrounds the conductor assembly is just as impressive. A proprietary blend of silicone and synthetic material produce a sleeve that is highly resistant to high heat as well as abrasion and tears. Available in universal kits and bulk lengths.

Product Features:
  • Bolt-on Performance
  • Custom Fit For Make And Model Listed
  • Wires Are Pre-Cut To Exact Specifications
  • Conductor core features DuPont Kevlar material for increased tensile strength
  • Durable outer sleeve is a proprietary compound for resistance to high heat or abrasion
  • Stainless steel terminals feature dual crimp tabs to grip wire conductor and outer jacket separately
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MSD Ignition – Wire Set; Black Super Conductor; LS-1 Truck Engines; 99-on (Part No.32823)

Wire Set; Black Super Conductor; LS-1 Truck Engines; 99-on

from

$109.99
The MSD 8.5mm super conductor wire is the performance wire. Engineered from the inside out, the 8.5 offers everything you have ever wanted in a wire; incredibly low resistance without electronic interference. In a single 12 inch length of super conductor wire there is only 40 – 50 ohms of resistance. That is the lowest resistance of any helically wound wire. To accomplish this, we use a copper alloy conductor due to it’s great voltage carrying capabilities. The low resistance results in less loss in spark energy so more reaches the spark plug. The conductor is wound extremely tight around a special center core. So tight in fact, that there is over 40 feet of conductor wrapped into a single foot of plug wire. This winding procedure, combined with a ferro-magnetic impregnated center core, produces an extremely effective electro magnetic interference (EMI) or choke. This choke, or suppression capability, keeps the EMI inside the wire where it cannot interfere with other electronics on your vehicle. The outer sleeve that surrounds the conductor assembly is just as impressive. A proprietary blend of silicone and synthetic material produce a sleeve that is highly resistant to high heat as well as abrasion and tears. Available in universal kits and bulk lengths.

Product Features:
  • Bolt-on Performance
  • Custom Fit For Make And Model Listed
  • Wires Are Pre-Cut To Exact Specifications
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DENSO – Spark Plug Wire Set: Carbon Core, 8 Wire Set (Part No.671-8161)

Spark Plug Wire Set: Carbon Core, 8 Wire Set

from

$97.99
DENSO First Time Fit Ignition Wire Sets are identical in form fit color and performance to the factory-installed wire sets. Every part of each wire sets construction meets or exceeds OE/OES standards.

Product Features:
  • Each wire is pre-cut to exact length so the wire set is ready to install right out of the box
  • Identical OE end caps are designed to “click” into place for easy installation and a secure fit
  • Strong connections – through a patented process, the terminals are attached to provide an extremely strong connection, ensuring the cable and boot will not separate during removal and installation
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Carquest Premium – Spark Plug Wire Set: 8 Wires, Increased performance, Designed for direct fit (Part No.35-8157)

Spark Plug Wire Set: 8 Wires, Increased performance, Designed for direct fit

from

$80.99
Product Features:
  • SAEJ2031 Class E cable resist heat (428 Deg. F), cold (-104 Deg. F), electrical interference, abrasion and oil.
  • Stainless steel magnetic winding delivers maximum voltage to the spark plug for more powerful, and longer spark resulting in optimum engine performance while reducing the chance for misfire, and eliminating radio static.
  • 100% Pure silicone external insulation resists oil penetration, for lifetime protection against wire set failure.
  • EPDM inner insulation stops power-robbing voltage leaks.
  • With Magnetic-impregnated Kevlar internal conductors – durable and break resistant
  • Engineered to meet OEM tolerances using variable pitch wire winding, creating better resistance to electric magnetic interference (E.M.I resistance).
  • Excellent interference suppression and consistent performance
  • Easy lock terminals for more convenient installation.
  • Thick silicon outer jacket for excellent heat resistance. Insulating EPDM based compound inner jacket helps minimize voltage drop and enhance durability.
  • Broad coverage available for most vehicles on the road today
  • Include grease pack to ensure easy installation and removal
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ACDelco – Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core (Part No.9748KK)

Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core

from

$73.99
ACDelco Professional Spark Plug Wire Sets consist of a set of wires, encased in an insulating material, connectors, and insulating boots, and are a high quality replacement for many vehicles on the road today. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plugs. These premium aftermarket replacement components are manufactured to meet your expectations for fit, form, and function.

Product Features:
  • Professional, premium aftermarket replacement
  • Provides the performance and dependability you expect from ACDelco
  • Manufactured to meet expectations for fit, form, and function
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Autopart International Inc – Ignition Wire Set (Part No.F10202008591API)

Ignition Wire Set

from

$83.88
Ignition Wire Set

Karlyn – Ignition Wire Set (Part No.F10202140926KAR)

Ignition Wire Set

from

$73.47
The Karlyn Ignition Wire Set incorporates two layers of high grade silicone for superior heat and voltage protection. The double extruded Silicone-over-Silicone wire contains 19 strands of tinned copper core which provides super conductivity and corrosion resistance.

Product Features:
  • OE-Equivalent.
  • OEM style connectors for easy Installation.
  • Resistant to high temperatures, corrosion and vibration.
  • Ignition noise suppressed.
  • Includes O.E. Type Connectors, Looms, Sensors and Harness Clips when required
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NGK – NGK Wire Set (Part No.51436)

NGK Wire Set

from

$78.99
NGK ultra-low resistance mag core wire sets provide outstanding performance and durability. High-temp premium silicone outer jacket and inner EPDM/silicone insulation contain high voltage currents for excellent dielectric strength. Stainless steel winding

Product Features:
  • PERFECT FIT FOR YOUR VEHICLE: Built to OEM tolerances with OE quality or better materials
  • BUILT TO LAST: Outer Jacket built to withstand temperatures greater than 250 degrees C, inner insulation EPDM or silicone for best dielectric strength
  • STAINLESS STEEL TERMINALS: Provide the highest possible retention to ensure positive connections through the life of the set
  • CYLINDER LEAD ID: Cylinder lead identification tags where possible make installation easier
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MSD Ignition – Wire Set; Street Fire; GM Truck; 4.8L; 5.3L; 6.0L; 98-05 (Part No.5574)

Wire Set; Street Fire; GM Truck; 4.8L; 5.3L; 6.0L; 98-05

from

$60.29
The street fire spark plug wires feature a low resistance conductor that’s wrapped in a sleek and durable black sleeve. The terminals are covered in black boots that protect the conductor from engine heat to ensure spark delivery.

Product Features:
  • Helically Wound Conductor
  • Suppresses Electro And Radio Noise
  • Great Strength And Durability
  • Heavy Duty Terminals For Secure Connection
  • 8mm Silicone/Synthetic Jacket Resists Heat
  • Improved Spark Delivery And Power
  • Silicone Boots Protect Against High Exhaust Temps
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Carquest Premium – Spark Plug Wire Set: 8 Wires, Increased performance, Designed for direct fit (Part No.35-8158)

Spark Plug Wire Set: 8 Wires, Increased performance, Designed for direct fit

from

$73.99
Product Features:
  • SAEJ2031 Class E cable resist heat (428 Deg. F), cold (-104 Deg. F), electrical interference, abrasion and oil.
  • Stainless steel magnetic winding delivers maximum voltage to the spark plug for more powerful, and longer spark resulting in optimum engine performance while reducing the chance for misfire, and eliminating radio static.
  • 100% Pure silicone external insulation resists oil penetration, for lifetime protection against wire set failure.
  • EPDM inner insulation stops power-robbing voltage leaks.
  • With Magnetic-impregnated Kevlar internal conductors – durable and break resistant
  • Engineered to meet OEM tolerances using variable pitch wire winding, creating better resistance to electric magnetic interference (E.M.I resistance).
  • Excellent interference suppression and consistent performance
  • Easy lock terminals for more convenient installation.
  • Thick silicon outer jacket for excellent heat resistance. Insulating EPDM based compound inner jacket helps minimize voltage drop and enhance durability.
  • Broad coverage available for most vehicles on the road today
  • Include grease pack to ensure easy installation and removal
See More

ACDelco – Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core (Part No.9748FF)

Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core

from

$90.99
ACDelco Professional Spark Plug Wire Sets consist of a set of wires, encased in an insulating material, connectors, and insulating boots, and are a high quality replacement for many vehicles on the road today. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plugs. These premium aftermarket replacement components are manufactured to meet your expectations for fit, form, and function.

Product Features:
  • Professional, premium aftermarket replacement
  • Provides the performance and dependability you expect from ACDelco
  • Manufactured to meet expectations for fit, form, and function
See More

Accel – Pc Wire Set 98-08 GM 8-Cyl (Part No.118063)

Pc Wire Set 98-08 GM 8-Cyl

from

$66.99
Pc Wire Set 98-08 GM 8-Cyl

ACDelco – Professional Ignition Wire Set (Part No.F1020575905ACD)

Professional Ignition Wire Set

from

$110.61
Built to match the Original Equipment in length and fit, ACDelco Professional Ignition Wire Sets also offer a performance advantage over many aftermarket products.

Product Features:
  • Designed to match Original Equipment wire sets in critical areas such as cable length and diameter, terminal design and insulator position.
  • Have broad coverage available for most vehicles on the road today from 1980 to present.
  • Provide a high degree of Radio Frequency Interference (RFI) suppression.
  • Are designed to offer fit, form and function for optimum performance.
  • Kevlar®-reinforced fiberglass core in select sets for increased strength.
  • Core sheathed in radio-static-absorbent material for increased RFI suppression.
  • Wire-wound, stainless-steel alloy conductor for maximum spark delivery and RFI suppression on most applications.
  • A layer of conductive heat-resistant latex for added durability.
  • Insulating rubber-based compound inner jacket helps minimize voltage drop and enhance durability.
  • Thick silicone outer jacket for excellent heat resistance.
See More

NGK – NGK Wire Set (Part No.51440)

NGK Wire Set

from

$75.99
NGK ultra-low resistance mag core wire sets provide outstanding performance and durability. High-temp premium silicone outer jacket and inner EPDM/silicone insulation contain high voltage currents for excellent dielectric strength. Stainless steel winding

Product Features:
  • PERFECT FIT FOR YOUR VEHICLE: Built to OEM tolerances with OE quality or better materials
  • BUILT TO LAST: Outer Jacket built to withstand temperatures greater than 250 degrees C, inner insulation EPDM or silicone for best dielectric strength
  • STAINLESS STEEL TERMINALS: Provide the highest possible retention to ensure positive connections through the life of the set
  • CYLINDER LEAD ID: Cylinder lead identification tags where possible make installation easier
See More

ACDelco – Professional Ignition Wire Set (Part No.F1020575903ACD)

Professional Ignition Wire Set

from

$115.93
Built to match the Original Equipment in length and fit, ACDelco Professional Ignition Wire Sets also offer a performance advantage over many aftermarket products.

Product Features:
  • Designed to match Original Equipment wire sets in critical areas such as cable length and diameter, terminal design and insulator position.
  • Have broad coverage available for most vehicles on the road today from 1980 to present.
  • Provide a high degree of Radio Frequency Interference (RFI) suppression.
  • Are designed to offer fit, form and function for optimum performance.
  • Kevlar®-reinforced fiberglass core in select sets for increased strength.
  • Core sheathed in radio-static-absorbent material for increased RFI suppression.
  • Wire-wound, stainless-steel alloy conductor for maximum spark delivery and RFI suppression on most applications.
  • A layer of conductive heat-resistant latex for added durability.
  • Insulating rubber-based compound inner jacket helps minimize voltage drop and enhance durability.
  • Thick silicone outer jacket for excellent heat resistance.
See More

NGK – NGK Wire Set (Part No.51430)

NGK Wire Set

from

$67.99
NGK ultra-low resistance mag core wire sets provide outstanding performance and durability. High-temp premium silicone outer jacket and inner EPDM/silicone insulation contain high voltage currents for excellent dielectric strength. Stainless steel winding

Product Features:
  • PERFECT FIT FOR YOUR VEHICLE: Built to OEM tolerances with OE quality or better materials
  • BUILT TO LAST: Outer Jacket built to withstand temperatures greater than 250 degrees C, inner insulation EPDM or silicone for best dielectric strength
  • STAINLESS STEEL TERMINALS: Provide the highest possible retention to ensure positive connections through the life of the set
  • CYLINDER LEAD ID: Cylinder lead identification tags where possible make installation easier
See More

Accel – Pc Wire Set 99-11 GM 8-Cyl (Part No.118064)

Pc Wire Set 99-11 GM 8-Cyl

from

$68.99
Pc Wire Set 99-11 GM 8-Cyl

Autopart International Inc – Ignition Wire Set (Part No.F10202047981API)

Ignition Wire Set

from

$65.22
Ignition Wire Set

ACDelco – GM Original Equipment Ignition Wire Set (Part No.F1020340076ACD)

GM Original Equipment Ignition Wire Set

from

$271.27
Built to match the original equipment in length and fit, ACDelco OES Ignition Wire Sets also offer a performance advantage over many aftermarket products.

Product Features:
  • ACDelco OES wire sets are designed to be like Original in critical areas such as cable length and diameter, terminal design and insulator position
  • Have broad coverage available for most vehicles on the road today from 1980 to present
  • Provide a high degree of Radio Frequency Interference (RFI) suppression
  • Are designed to offer fit, form and function for optimum performance
  • Kevlar reinforced fiberglass core in select sets for increased strength
  • Core sheathed in radio-static absorbent material for increased RFI suppression
  • Wire-wound, stainless steel alloy conductor for maximum spark delivery and RFI suppression on most applications
  • A layer of conductive heat-resistant latex for added durability
  • Insulating rubber-based compound inner jacket helps minimize voltage drop and enhance durability
  • Thick silicone outer jacket for excellent heat resistance
  • Limited lifetime warranty*
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Accel – Chevy/GM 04-01 3/4/1Ton 8.1L-Black (Part No.9065CK)

Chevy/GM 04-01 3/4/1Ton 8.1L-Black

from

$194.99
ACCEL now offers the cure for burnt spark plug boots with Extreme 9000 Ceramic wire kits. The 8mm Ferro-Spiral core wire now has black ceramic boots on the spark plug end of the wires. Ceramic boots withstand up to 2,000 degrees. Great for running headers with close tolerances, an engine bay with little room, or an RV with boots that melt because of heat. Ultra high temperature double silicone construction wire rated at 600 degrees fahrenheit peak. 500 ohms/ft Ferro-Spiral core developed for performance use. Excellent energy delivery to the spark plugs, while providing the highest level of RFI/EMI suppression. Stainless steel spark plug terminals for maximum spark energy to the plugs. Pre-made to factory lengths for a perfect fit.

Product Features:
  • Ceramic boots withstand up to 2,000░ Fahrenheit
  • Ceramic boots withstand up to 2,000° Fahrenheit
  • 8mm double silicone construction black wire rated at 600░ F rated
  • 8mm double silicone construction black wire rated at 600° F rated
  • 500 Ohms/foot ferro sprial core offers the highest level of RFI/EMI suppression
  • Stainless Steel Plug Terminals
  • Black ceramic for good looks
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ACDelco – Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core (Part No.9748UU)

Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core

from

$72.99
ACDelco Professional Spark Plug Wire Sets consist of a set of wires, encased in an insulating material, connectors, and insulating boots, and are a high quality replacement for many vehicles on the road today. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plugs. These premium aftermarket replacement components are manufactured to meet your expectations for fit, form, and function.

Product Features:
  • Professional, premium aftermarket replacement
  • Provides the performance and dependability you expect from ACDelco
  • Manufactured to meet expectations for fit, form, and function
See More

Ignition Wires Brands You Can Trust For Your GMC Sierra 2500 HD

9 trusted brands of Ignition Wires line our shelves, ready to help keep your GMC Sierra 2500 HD running smooth. Below are some of the most popular brands and their top Ignition Wires offerings:

Most Purchased GMC Sierra 2500 HD Ignition Wires from Carquest Premium

When you buy the most frequently purchased Carquest Premium brand Ignition Wires, you can be confident it will be the right part for your GMC Sierra 2500 HD. Here are the Carquest Premium Ignition Wires Advanced Auto customers buy the most:
Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core
from $72.99
This product is not rated
Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core
Standard Spark Plug Wires

FAQs for GMC Sierra 2500 HD Ignition Wires

What are the most purchased Ignition Wires for the GMC Sierra 2500 HD?

Out of 23 Ignition Wires for the GMC Sierra 2500 HD, the most popular in our inventory are:
Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core
from $72.99
This product is not rated
Specific FitSpark Plug Wire Set: Fiberglass Reinforced Latex Graphite Core
Standard Spark Plug Wires
Wire Set; Street Fire; GM Truck; 4.8L; 5.3L; 6.0L; 98-05
from $60.29
(5)
Wire Set; Street Fire; GM Truck; 4.8L; 5.3L; 6.0L; 98-05
Standard Spark Plug Wires
Wire Set; Super Conductor; LS-1 Truck Engines; 99
from $109.99
(10)
Wire Set; Super Conductor; LS-1 Truck Engines; 99
Optional Spark Plug Wires

What are the top-rated GMC Sierra 2500 HD Ignition Wires?

Top-rated Ignition Wires for your GMC Sierra 2500 HD based on customer reviews/ratings are:
Wire Set; Black Super Conductor; LS-1 Truck Engines; 99-on
from $109.99
(11)
Wire Set; Black Super Conductor; LS-1 Truck Engines; 99-on
“I replaced my old Wires in my 2006 Silverado 93k miles with these. They do fit even though it says its not compatible. This is my second set & they ar”
Spark Plug Wire Set: Carbon Core, 8 Wire Set
from $97.99
(1)
Spark Plug Wire Set: Carbon Core, 8 Wire Set
“2008 chevy siiverado 6.0 liter.Truck has 90,000 mile’s thought it was time to change plug’s and wire’s. truck may run a little smoother at idle.”