GMC Sierra 2500 HD Engine Gaskets and Seals

Your One-Stop Shop For Trusted GMC Sierra 2500 HD Engine Gaskets and Seals

If you’re in search of GMC Sierra 2500 HD Engine Gaskets and Seals aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 66 Engine Gaskets and Seals from top brands with prices ranging from $3.99 to $489.99.

Beyond great prices, we stock trusted brands manufacturing all types of Engine Gaskets and Seals for your GMC Sierra 2500 HD.

And don’t forget to read customer reviews across all Engine Gaskets and Seals categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Engine Gaskets and Seals have to cost top dollar, and we prove it. Browse our top GMC Sierra 2500 HD Engine Gaskets and Seals below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential GMC Sierra 2500 HD Engine Gaskets and Seals

GM Genuine Parts – Oil Pan Cover Gasket: Nitrile Coated SS (Part No.12611384)

Oil Pan Cover Gasket: Nitrile Coated SS

from

$9.99
GM Genuine Parts Engine Oil Pan Cover Gasket are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Dorman – Help – Coolant Bypass Seals (Part No.56390)

Coolant Bypass Seals

from

$11.49
This engine coolant water bypass gasket is designed to match the fit and function of the original gasket on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this engine coolant water bypass gasket is designed to match the fit and function of the original gasket on specified vehicles
  • Restores functionality – this gasket is made to fit and fully restore functionality after the original part fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Main Seal Cover Kit (Part No.635-518)

Main Seal Cover Kit

from

$83.99
This direct replacement rear main seal cover kit matches the fit and function of the original equipment cover for a reliable repair. This part has undergone extensive testing to ensure adherence to precise design standards.

Product Features:
  • Direct replacement – this rear main seal cover kit matches the factory design, and includes a new gasket, installation hardware, and an updated seal design for superior leak prevention
  • Durable construction – the timing cover in this kit is made of die-cast aluminum for a leak-free fit and durability
  • Convenient solution – this kit includes a new gasket and installation hardware for a complete repair
  • Quality tested – this part has undergone extensive testing to ensure a quality fit and long service life
See More

Felpro – Engine Oil Filler Cap Seal (Part No.73193)

Engine Oil Filler Cap Seal

from

$5.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

Felpro – Engine Lifter Valley Cover Gasket Set (Part No.MS 92465)

Engine Lifter Valley Cover Gasket Set

from

$42.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for repair applications
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
  • Includes all parts needed to complete the repair
See More

Melling – Engine Oil Strainer Gasket Set (Part No.M29517)

Engine Oil Strainer Gasket Set

from

$3.99
Made In USA. Installing an oil pump screen can often cause damage to the protective gaskets and O Rings if the screen assembly is not properly installed. In the event that the original seals are damaged or accidently discarded Melling offers a replacement gasket set for oil pump screen installations covering the LS oil pumps. Each package conveniently contains both replacement O Rings needed to complete the oil pump screen installation. These gasket sets can be used for the M295, M295HV, M355, M365, 10295, 10296 and 10355 oil pumps.
See More

Felpro – Engine Oil Pan Gasket Set – High-temperature Rubber-coated fiber (Part No.OS 30748)

Engine Oil Pan Gasket Set - High-temperature Rubber-coated fiber

from

$20.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL – Manufactured with rubber compounds to ensure a consistent and long-life seal across the entire oil pan
  • PREVENTS OVERTIGHTENING – Torque limiters help eliminate overtightening and gasket splitting and extruding (where applicable)
  • OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • ENGINEERING EXPERTISE – Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
  • ENGINEERING EXPERTISE – Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
See More

Carquest Premium – Automatic Transmission Fluid Temperature Sensor (Part No.SBE2079)

Automatic Transmission Fluid Temperature Sensor

from

$107.99
The Automatic Transmission Fluid Temperature Sensor provides an input to the transmission control module as to the operating temperature of the automatic transmission fluid under the many operating conditions. The transmission control module will provide the transmission hydraulic circuits the optimal fluid pressure for current temperature conditions.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • Lead frame terminal size and location determined using image dimension measuring system or 3D laser scanner.
  • Application matched components ensures system operation in like new condition.
See More

Felpro – Engine Valve Stem Oil Seal Set (Part No.SS 72551)

Engine Valve Stem Oil Seal Set

from

$57.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • RIGHT TYPE – Valve stem seals designs are application-specific for the repair occasion using either deflector (umbrella) seals, O-ring style or positive seals
  • QUALITY MATERIALS – Each valve stem seal features materials based on the specific application for your vehicle repair
  • ENGINEERING EXPERTISE – Parts are reviewed, validated and approved by Fel-Pro engineers through rigorous research, development and testing
  • INSTALLATION AID – Installation tool included to protect inner lip of seal from damage during seal installation
  • COVERAGE – Available for domestic and foreign nameplate vehicles
See More

Felpro – Engine Timing Cover Gasket Set (Part No.TCS 45055)

Engine Timing Cover Gasket Set

from

$88.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered for the sealing repair environment
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
  • Includes all the parts necessary to complete the repair unless otherwise noted
See More

Felpro – Engine Timing Cover Gasket Set (Part No.TCS 46007)

Engine Timing Cover Gasket Set

from

$40.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Timing cover set includes gaskets and seals necessary for timing chain/belt replacement job
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
See More

Felpro – Engine Conversion Gasket Set (Part No.CS 9284-1)

Engine Conversion Gasket Set

from

$318.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
See More

Felpro – Engine Conversion Gasket Set (Part No.CS 26269)

Engine Conversion Gasket Set

from

$142.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Conversion Sets (CS) provide every gasket for lower engine work – add a Head Set (HS) for complete engine overhaul work
  • Application specific design to ensure a perfect fit
  • Meets or exceeds all original equipment specifications
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
  • Includes all the parts necessary to complete the repair unless otherwise noted
  • Includes all the parts necessary to complete the repair unless otherwise noted
See More

MAHLE Original – Fuel Injection Plenum Gasket (Part No.G31915)

Fuel Injection Plenum Gasket

from

$4.49
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • For engines having a plenum chamber (upper intake manifold).
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Victor Reinz – Fuel Injection Plenum Gasket (Part No.71-14603-00)

Fuel Injection Plenum Gasket

from

$5.29
Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
  • Meets or exceeds OE specifications
See More

Dorman – Silicon Valve Cover Gasket Set: Exact Fit, 25 Pieces (Part No.615-203)

Silicon Valve Cover Gasket Set: Exact Fit, 25 Pieces

from

$85.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.

Product Features:
  • Direct replacement – this valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles
  • Ideal solution – engineered to help ensure a secure seal when an original gasket is due for service or damaged
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
  • Contents: 1 Valve Cover Gasket; 8 Injector Cup O Rings; 4 Valve Cover Bolts; 7 Assorted Fuel Line Gaskets; 4 Injector Seal O Rings; 1 Coolant Outlet O Ring
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50504 R-1)

Engine Valve Cover Gasket Set

from

$37.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
  • SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Felpro – Engine Oil Cooler Gasket Set (Part No.ES 73231)

Engine Oil Cooler Gasket Set

from

$42.99
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Includes all parts needed to complete the repair
See More

Felpro – Engine Gasket Set (Part No.260-1956)

Engine Gasket Set

from

$469.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Includes all parts needed to complete the repair
See More

Sealed Power – Engine Gasket Set (Part No.260-3154)

Engine Gasket Set

from

$469.99
Sealed Power parts provide innovative designs, use leading-edge materials and utilize ISO & QS certified manufacturing in order to deliver top quality products that meet the rigorous demands of today’s modern engines.

Product Features:
  • Each 260 gasket set includes Fel-Pro gaskets (Number 1 brand of gaskets)
  • Provides the exact gaskets the application requires.
  • State-of-the-art manufacturing
  • Exacting tolerances
  • Meets or exceeds OEM specifications
See More

Felpro – Fuel Pump Mounting Gasket (Part No.73158)

Fuel Pump Mounting Gasket

from

$5.99
Fuel Pump Mounting Gasket

National – Multi-Purpose Seal (Part No.4333N)

Multi-Purpose Seal

from

$20.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Oil Seal (Part No.S-4333N)

Oil Seal

from

$13.49
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

Engine Gaskets and Seals Brands You Can Trust For Your GMC Sierra 2500 HD

11 trusted brands of Engine Gaskets and Seals line our shelves, ready to help keep your GMC Sierra 2500 HD running smooth. Below are some of the most popular brands and their top Engine Gaskets and Seals offerings:

Popular Dorman Engine Gaskets and Seals

Dorman products for the GMC Sierra 2500 HD span several categories. Some of the highest-rated Dorman Engine Gaskets and Seals that will fit your GMC Sierra 2500 HD are:
Main Seal Cover Kit
from $83.99
(19)
Main Seal Cover Kit
Rear Main Seal Sets
Coolant Bypass Seals
from $11.49
(3)
Coolant Bypass Seals
Water Connection Gaskets

Most Purchased GMC Sierra 2500 HD Engine Gaskets and Seals from Felpro

When you buy the most frequently purchased Felpro brand Engine Gaskets and Seals, you can be confident it will be the right part for your GMC Sierra 2500 HD. Here are the Felpro Engine Gaskets and Seals Advanced Auto customers buy the most:
Engine Oil Pan Gasket Set - PermaDry molded rubber
from $67.99
(74)
Engine Oil Pan Gasket Set – PermaDry molded rubber
Oil Pan Gaskets
Engine Valve Cover Gasket Set
from $37.99
(68)
Engine Valve Cover Gasket Set
Valve Cover Gaskets
Main Seal Cover Kit
from $83.99
(19)
Main Seal Cover Kit
Rear Main Seal Sets

FAQs for GMC Sierra 2500 HD Engine Gaskets and Seals

What are the most purchased Engine Gaskets and Seals for the GMC Sierra 2500 HD?

Out of 66 Engine Gaskets and Seals for the GMC Sierra 2500 HD, the most popular in our inventory are:
Engine Valve Cover Gasket Set
from $26.99
(18)
Engine Valve Cover Gasket Set
Valve Cover Gaskets
Engine Lifter Valley Cover Gasket Set
from $42.99
(20)
Engine Lifter Valley Cover Gasket Set
Engine Lifter Valley Cover Gasket Sets
Multi-Purpose Seal
from $20.99
(15)
Multi-Purpose Seal
Power Take Off Shaft Seal

What are the top-rated GMC Sierra 2500 HD Engine Gaskets and Seals?

Top-rated Engine Gaskets and Seals for your GMC Sierra 2500 HD based on customer reviews/ratings are:
Oil Seal
from $13.49
(4)
Oil Seal
“worked great”
Engine Valve Stem Oil Seal Set
from $37.99
(3)
Engine Valve Stem Oil Seal Set
“easy to install fit well.”
Engine Valve Stem Oil Seal Set
from $32.99
(2)
Engine Valve Stem Oil Seal Set
“Valve stem seals worked out great, used on heads,cam corvette z06.”