2025 GMC Sierra 2500 HD Engine Parts

Essential 2025 GMC Sierra 2500 HD Engine Parts

GM Genuine Parts – Oil Pan Seal (Part No.12621086)

Oil Pan Seal

from

$13.99
GM Genuine Parts Engine Oil Pan Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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ACDelco – GM Original Equipment Engine Oil Pan Gasket (Part No.A6130659422ACD)

GM Original Equipment Engine Oil Pan Gasket

from

$16.16
ACDelco GM Original Equipment Engine Oil Pan Gasket is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Gen III/IV Lifter Guide (Part No.12595365)

Gen III/IV Lifter Guide

from

$14.99
GM Genuine Parts Engine Valve Lifter Guide are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Felpro – Lower Oil Pan Gasket Set: High-Temperature Rubber-Coated Fiber, 1 Piece Set (Part No.OS 30838)

Lower Oil Pan Gasket Set: High-Temperature Rubber-Coated Fiber, 1 Piece Set

from

$18.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Victor Reinz – Engine Oil Pan Gasket Set (Part No.10-10437-01)

Engine Oil Pan Gasket Set

from

$58.99
Built to meet or exceed the standards of original equipment manufacturers around the world and avoid comebacks Victor Reinz oil pan gaskets deliver the seal that prevents drops on the driveway. Victor Reinz engineers select the best designs and materials for the specific application. The level of sophistication in oil pan gasket form and function has jumped greatly in recent years, with the gasket often being an integral part of the manufacturers efforts to control engine noise, vibration, and harshness (NVH). Only a company with innovative gasket technology can supply the right gasket for every application, new or old.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

GM Genuine Parts – Oil Pan Gasket (Part No.12612350)

Oil Pan Gasket

from

$64.99
GM Genuine Parts Engine Oil Pan Gaskets are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Felpro – Oil Pan Gasket Set: PermaDry Molded Rubber, 1 Piece Set (Part No.OS 30714 R)

Oil Pan Gasket Set: PermaDry Molded Rubber, 1 Piece Set

from

$37.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Felpro – Upper Oil Pan Gasket Set: PermaDry Molded Rubber, 1 Piece Set (Part No.OS 30693 R)

Upper Oil Pan Gasket Set: PermaDry Molded Rubber, 1 Piece Set

from

$66.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL — Manufactured with rubber compounds to ensure a consistent and long-life seal across the entire oil pan
  • PREVENTS OVERTIGHTENING — Torque limiters help eliminate overtightening and gasket splitting and extruding (where applicable)
  • OE-STYLE REPLACEMENT GASKET — Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • ENGINEERING EXPERTISE — Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
  • ENGINEERING EXPERTISE — Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
See More

MAHLE Original – OIL PAN SET (Part No.OS32364)

OIL PAN SET

from

$35.99
MAHLE gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • Oil pan gasket set contains all gaskets required.
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Felpro – OIL PAN GASKET SET (Part No.OS 30748)

OIL PAN GASKET SET

from

$19.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL — Manufactured with rubber compounds to ensure a consistent and long-life seal across the entire oil pan
  • PREVENTS OVERTIGHTENING — Torque limiters help eliminate overtightening and gasket splitting and extruding (where applicable)
  • OE-STYLE REPLACEMENT GASKET — Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • ENGINEERING EXPERTISE — Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
  • ENGINEERING EXPERTISE — Parts are designed, tested, validated and approved by Fel-Pro engineers through rigorous research and development
See More

ACDelco – GM Original Equipment Engine Oil Pan Gasket (Part No.A6130205054ACD)

GM Original Equipment Engine Oil Pan Gasket

from

$35.24
ACDelco GM Original Equipment Engine Oil Pan Gasket is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
See More

Victor Reinz – Engine Oil Pan Gasket Set (Part No.10-10238-01)

Engine Oil Pan Gasket Set

from

$33.49
Built to meet or exceed the standards of original equipment manufacturers around the world and avoid comebacks Victor Reinz oil pan gaskets deliver the seal that prevents drops on the driveway. Victor Reinz engineers select the best designs and materials for the specific application. The level of sophistication in oil pan gasket form and function has jumped greatly in recent years, with the gasket often being an integral part of the manufacturers efforts to control engine noise, vibration, and harshness (NVH). Only a company with innovative gasket technology can supply the right gasket for every application, new or old.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

ACDelco – GM Original Equipment Engine Oil Pan Gasket (Part No.A6130409907ACD)

GM Original Equipment Engine Oil Pan Gasket

from

$79.06
ACDelco GM Original Equipment Engine Oil Pan Gasket is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50622 R)

Engine Valve Cover Gasket Set

from

$71.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50907 R)

Engine Valve Cover Gasket Set

from

$21.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • SUPERIOR SEAL — Manufactured with rubber compounds to help ensure a consistent and long-life seal
  • PRECISE DESIGN — Engineered to work with the embossed cover and pan flanges
  • PREVENTS OVERTIGHTENING — Features compression limiters incorporated into the design to help eliminate overtightening (application specific)
  • OE-STYLE REPLACEMENT GASKET — Engineered for OE-style molded rubber gasket replacement
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
See More

MAHLE Original – Valve Cover Gasket Set (Part No.VS50551)

Valve Cover Gasket Set

from

$287.99
MAHLE gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • Valve cover gasket set contains all the gaskets required – may also contain spark plug tube seals and grommets if necessary.
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50684 R)

Engine Valve Cover Gasket Set

from

$93.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

MAHLE Original – Valve Cover Gasket Set (Part No.VS50549)

Valve Cover Gasket Set

from

$113.99
MAHLE gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • Valve cover gasket set contains all the gaskets required – may also contain spark plug tube seals and grommets if necessary.
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50822 R)

Engine Valve Cover Gasket Set

from

$82.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Dorman – Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces (Part No.904-380)

Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces

from

$91.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.

Product Features:
  • Direct replacement – this valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles
  • Ideal solution – engineered to help ensure a secure seal when an original gasket is due for service or damaged
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

ACDelco – GM Original Equipment Valve Cover Gasket (Part No.A8030432024ACD)

GM Original Equipment Valve Cover Gasket

from

$33.19
The ACDelco GM Original Equipment Valve Cover Gasket is a GM-recommended replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
See More

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50504 R)

Engine Valve Cover Gasket Set

from

$25.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Dorman – Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces (Part No.904-171)

Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces

from

$136.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.

Product Features:
  • Direct replacement – this valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles
  • Ideal solution – engineered to help ensure a secure seal when an original gasket is due for service or damaged
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

ACDelco – Valve Cover Gasket (Part No.A8030580015ACD)

Valve Cover Gasket

from

$7.96
Valve Cover Gasket

Felpro – Engine Valve Cover Gasket Set (Part No.VS 50554 R)

Engine Valve Cover Gasket Set

from

$28.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Victor Reinz – Molded Rubber Valve Cover Gasket Set: Direct Fit, Includes Grommets, 50 Pieces (Part No.15-10414-01)

Molded Rubber Valve Cover Gasket Set: Direct Fit, Includes Grommets, 50 Pieces

from

$93.99
Oil drops on the driveway are a distant memory thanks to sophisticated engine valve cover and gasket designs. Victor Reinz is at the forefront of engineering the latest sealing technology. Although the primary task of valve cover gaskets is to seal oil and oil spray, they must withstand high temperatures brought on by nearby exhaust manifolds, exhaust crossovers in the cylinder heads, and EGR systems. Victor Reinz valve cover gaskets deliver the quality materials you demand. Where appropriate, Victor Reinz valve cover gaskets are designed with compression limiters to prevent over-torquing, splitting, or the need to retorque.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
  • Meets or exceeds OE specifications
  • Zero engine leakage for late model vehicles.
See More

Felpro – VALVE COVER GASKET SET (Part No.VS 50821 R)

VALVE COVER GASKET SET

from

$203.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • DESIGNED FOR IMPERFECT SEALING SURFACES — Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
  • ENGINEERED TO PERFORM — Proprietary cork-rubber formulation
  • SUPERIOR SEAL — Highly conformable to accommodate for the imperfect sealing surfaces
  • EVERY PART FOR THE REPAIR — Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
  • REAL-WORLD TESTED — Parts are tested on-vehicle and validated to ensure optimal performance on the road
See More

Dorman – Silicon Valve Cover Gasket Set: Exact Fit, 25 Pieces (Part No.615-203)

Silicon Valve Cover Gasket Set: Exact Fit, 25 Pieces

from

$69.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.

Product Features:
  • Direct replacement – this valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles
  • Ideal solution – engineered to help ensure a secure seal when an original gasket is due for service or damaged
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

2025 GMC Sierra 2500 HD Engine Parts

You count on your 2025 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Engine Parts. With 4 Engine Parts ranging in price from $5.49 to $21.49, you’re sure to find everything you need for your 2025 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Engine Parts brand, we stock 2 different brands like GM Genuine and Felpro. 2025 GMC Sierra 2500 HD Engine Parts start as low as $5.49!

Did we mention you can order your Engine Parts from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Engine Parts inventory for your 2025 GMC Sierra 2500 HD below to get started!

FAQs for 2025 GMC Sierra 2500 HD Engine Parts

What are the most purchased Engine Parts for the 2025 GMC Sierra 2500 HD?

Out of 4 Engine Parts for the 2025 GMC Sierra 2500 HD, the most popular in our inventory are:
Gen III/IV Lifter Guide
from $14.99
This product is not rated
Gen III/IV Lifter Guide
Engine Valve Lifter Guides
Engine Valve Cover Gasket Set
from $21.49
This product is not rated
Engine Valve Cover Gasket Set
Valve Cover Gaskets
Oil Pan Gasket
from $5.49
This product is not rated
Oil Pan Gasket
Oil Pan Gaskets