2022 Mercedes-Benz Sprinter 2500 Engine Cooling Parts

Keep Your 2022 Mercedes-Benz Sprinter 2500 in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2022 Mercedes-Benz Sprinter 2500 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Water Pumps, Thermostat and Water Outlet Assemblies, and Coolant Temperature Sensors. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium. For example, Carquest Premium Engine Cooling Parts start at just $19.99 with an average 4.4 star rating. With over 3 reviews and a solid 5 star average, you can shop with confidence knowing other Mercedes-Benz Sprinter 2500 owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Part at Advance Auto Parts is around $110.74, with a range that starts at $19.99 and goes up to $422.99. With 7 options in stock from 3 trusted brands, finding the right fit is easy. Popular picks like Coolant Temperature Sensor 1TS1049, Integrated Thermostat Housing: With Seal, 189 Degrees, and Engine Water Pump: New, Gasket/Seals Included start at just $21.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Air Conditioning Parts. At Advance Auto Parts, we’re here to help you keep your 2022 Mercedes-Benz Sprinter 2500 in peak condition, inside and out.

Essential 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Parts

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T2288)

Engine Water Pump: New, Gasket/Seals Included

from

$179.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
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Carquest Premium – Universal Fan Clutch (Part No.216085)

Universal Fan Clutch

from

$213.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
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Carquest Premium – Universal Fan Clutch (Part No.216084)

Universal Fan Clutch

from

$422.99
Universal Fan Clutch

Carquest Premium – Coolant Temperature Sensor 1TS1049 (Part No.WTC1122)

Coolant Temperature Sensor 1TS1049

from

$21.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
  • O-rings, seals or thread sealant are included if required
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
See More

Carquest Premium – Standard Reservoir Cap: 21 PSI (Part No.10253)

Standard Reservoir Cap: 21 PSI

from

$19.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Rein – Cap-Expansion Tank (Part No.CPE0040)

Cap-Expansion Tank

from

$17.99
Rein Automotive OE quality caps fit european vehicles the way the original manufacturer intended. Designed to be direct replacement for the OE cap. Rein caps are designed to match or exceed the OE materials used and are produced to the highest standards to ensure long service life.

Product Features:
  • Prevents moisture and debris from entering and contaminating the system
  • Direct fit
  • Manufactured to strict engineering standards/specifications in materials and tolerances
  • Produced by an original equipment supplier
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Carquest Premium – Reservoir Cap (Part No.T90)

Reservoir Cap

from

$28.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.
See More

Dorman – Thermostat Assembly: Includes Gasket, Housing, and Thermostat (Part No.902-5183)

Thermostat Assembly: Includes Gasket, Housing, and Thermostat

from

$45.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 198 Degrees (Part No.902-5850)

Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 198 Degrees

from

$103.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Integrated Thermostat Housing: With Seal, 189 Degrees (Part No.623-189)

Integrated Thermostat Housing: With Seal, 189 Degrees

from

$61.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable

Product Features:


    Product Features:
    • High grade stainless steel and copper construction
    • Meets or exceeds OEM standards
    • Consistent and precise response to cooling system needs
    • Original equipment design for worry-free direct fit replacement
    • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: 198 Degrees (Part No.962-198)

Integrated Thermostat Housing: 198 Degrees

from

$98.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Most Popular Water Pump for 2022 Mercedes-Benz Sprinter 2500s

Enhance your 2022 Mercedes-Benz Sprinter 2500 with this popular Water Pump we have in stock, for $179.99.

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T2288)

Engine Water Pump: New, Gasket/Seals Included

from

$179.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
See More

Best-Selling 2022 Mercedes-Benz Sprinter 2500 Thermostat and Water Outlet Assemblies

Upgrade your Sprinter 2500 with one of our 2 best-selling Thermostat and Water Outlet Assemblies.

Motorad – Integrated Thermostat Housing: With Seal, 189 Degrees (Part No.623-189)

Integrated Thermostat Housing: With Seal, 189 Degrees

from

$61.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable

Product Features:


Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 198 Degrees (Part No.902-5850)

Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 198 Degrees

from

$103.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Top-Quality Coolant Temperature Sensors for 2022 Mercedes-Benz Sprinter 2500s

Choose a high-quality OEM or aftermarket Coolant Temperature Sensor for Mercedes-Benz Sprinter 2500s and enjoy top-notch performance from $21.99.

Carquest Premium – Coolant Temperature Sensor 1TS1049 (Part No.WTC1122)

Coolant Temperature Sensor 1TS1049

from

$21.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
  • O-rings, seals or thread sealant are included if required
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
See More

Top Picks for 2022 Mercedes-Benz Sprinter 2500 Radiator Fan Clutch

Invest in one of our 2 durable Radiator Fan Clutch for your 2022 Mercedes-Benz, knowing you’re getting trusted brands and expert craftsmanship.

Carquest Premium – Universal Fan Clutch (Part No.216084)

Universal Fan Clutch

from

$422.99
Universal Fan Clutch

Carquest Premium – Universal Fan Clutch (Part No.216085)

Universal Fan Clutch

from

$213.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
See More

Our Top-Rated Coolant Reservoir Caps for 2022 Mercedes-Benz Sprinter 2500s

Make a smart move for your 2022 Mercedes-Benz Sprinter 2500 with our Coolant Reservoir Cap for $19.99.

Carquest Premium – Standard Reservoir Cap: 21 PSI (Part No.10253)

Standard Reservoir Cap: 21 PSI

from

$19.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Top-Rated Engine Cooling Part Brands For Your 2022 Mercedes-Benz Sprinter 2500

When it comes to finding the perfect Engine Cooling Part for your 2022 Mercedes-Benz Sprinter 2500, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 3 trusted brands. We carry the most popular Engine Cooling Part brands including Carquest Premium, and more, all known for their exceptional customer ratings (average brand rating of 4.4 stars) and competitive prices, as low as $19.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2022 Mercedes-Benz Sprinter 2500, providing peace of mind with parts that meet or exceed OEM standards.

Popular Carquest Premium 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2022 Mercedes-Benz Sprinter 2500, Advance Auto Parts has exactly what you need with our selection of Carquest Premium Engine Cooling Parts. We have 1 Carquest Premium Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $19.99, you’ll find the perfect Engine Cooling Part for your needs and budget. Carquest Premium Engine Cooling Parts for the 2022 Mercedes-Benz Sprinter 2500 come highly rated, with over 1 customer reviews and an impressive average rating of 4.4 stars. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Standard Reservoir Cap: 21 PSI
from $19.99
(1)
Standard Reservoir Cap: 21 PSI
“Works well, looks identical to OEM!”

FAQs for 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2022 Mercedes-Benz Sprinter 2500s?

Out of 7 Engine Cooling Parts that fit 2022 Mercedes-Benz Sprinter 2500s, the following parts are the top sellers:

What’s the price range for 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2022 Mercedes-Benz Sprinter 2500 range from $19.99 up to $422.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2022 Mercedes-Benz Sprinter 2500?

The average price for Engine Cooling Parts for the 2022 Mercedes-Benz Sprinter 2500 is $110.74. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Mercedes-Benz Sprinter 2500 model years?

Yes, we carry Engine Cooling Parts for 14 model years of Mercedes-Benz Sprinter 2500s between 2010 and 2025. The following model years are the most popular for Engine Cooling Part purchases: 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Engine Cooling Parts for my 2022 Mercedes-Benz Sprinter 2500?

The cheapest 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2022 Mercedes-Benz models?

Yes. We stock Engine Cooling Parts for 15 other popular 2022 Mercedes-Benz models. Some of the most popular are 2022 E350 Engine Cooling Parts, 2022 Sprinter 3500 Engine Cooling Parts, 2022 C300 Engine Cooling Parts, 2022 Metris Engine Cooling Parts, and 2022 S500 Engine Cooling Parts.

What are the top-rated Engine Cooling Parts that fit the 2022 Mercedes-Benz Sprinter 2500?

The one 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Part we have in stock is the Standard Reservoir Cap: 21 PSI. It is rated 5 stars and costs $19.99.

What types of Engine Cooling Parts do you sell for my 2022 Mercedes-Benz Sprinter 2500?

As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2022 Mercedes-Benz Sprinter 2500:

Can I get help with 2022 Mercedes-Benz Sprinter 2500 Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Engine Cooling Parts and more.

What is your return policy for Mercedes-Benz Sprinter 2500 Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Mercedes-Benz Sprinter 2500 Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.