2022 Mercedes-Benz E350 Engine Oils

Enhance and Protect Your 2022 Mercedes-Benz E350 with Quality Engine Oils

Maintaining the performance of your 2022 Mercedes-Benz E350 starts with choosing the right parts, and high-quality Engine Oil help ensure a reliable and efficient vehicle. At Advance Auto Parts, we offer Engine Oils specifically for the 2022 Mercedes-Benz E350, ensuring a perfect fit and lasting durability. Choosing to shop with Advance Auto Parts means you’re making a smart decision to prioritize both quality and reliability for your vehicle.

Affordable and Reliable Engine Oils for Every Budget

Finding affordable, quality Engine Oil is easy at Advance Auto Parts. With prices starting as low as $7.49 and an average price of $41.68, you can choose one that fits your budget while delivering the quality you expect. Our Engine Oils are competitively priced, ranging from $7.49 to $154.99, so you get value without compromising on strength or reliability.
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Engine Oils for Your 2022 Mercedes-Benz E350

Mobil 1 – Advanced 0W-30 Full Synthetic Motor Oil, Reduces Deposits, 1 Quart (Part No.47104)

Advanced 0W-30 Full Synthetic Motor Oil, Reduces Deposits, 1 Quart

from

$11.99
Mobil 1 ESP 0W-30 is an advanced full synthetic oil specially formulated for passenger car diesels that have the latest diesel particulate filters (DPFs) and gasoline catalytic converters (CATs). The proprietary full synthetic motor oil is designed to help deliver outstanding performance and protection in conjunction with potential fuel economy benefits. Mobil 1 ESP has active cleaning agents that help to reduce deposits and sludge buildup for a cleaner engines. Helps to reduce oil aging with outstanding oxidation stability for extended drain interval protection. Low ash, sulfur, and phosphorous content help to reduce particulate buildup in DPFs and reduce poisoning of CATs. Excellent low temperature capabilities for quick cold-weather starting and ultra-fast protection. Mobil 1 is America’s leading synthetic motor oil brand at retail (1) , recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR. ((1) Source: The NPD Group/ Retail Tracking Service/ Dollar Sales/ PCMO Full Synthetic/ 52 weeks ending July 1, 2023)

Product Features:
  • Mobil 1 ESP X2 full synthetic motor oil 0W-30 provides outstanding protection to keep your engine running like new.
  • Low ash, sulfur, and phosphorous content help to reduce particulate build up in DPFs
  • Active cleaning agents that help to reduce deposits and sludge buildup for a cleaner engine
  • Helps to reduce oil aging with outstanding oxidation stability for extended drain interval protection
  • Excellent low temperature capabilities for quick cold-weather starting and ultra-fast protection
  • Manufacturer Part Number: 124547
  • Advanced Full Synthetic Formula: Mobil 1 ESP 0W-30 is specially formulated for passenger car diesels with the latest diesel particulate filters (DPFs) and gasoline catalytic converters (CATs).
  • Outstanding Performance and Protection: Designed to deliver exceptional performance and protection, this motor oil also offers potential fuel economy benefits.
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FRAM – 0W-40 Full Synthetic Motor Oil, Exceptional Film Strength, 1 Quart (Part No.F904)

0W-40 Full Synthetic Motor Oil, Exceptional Film Strength, 1 Quart

from

$7.49
FRAM Engine Oil Full Synthetic SAE 0W-40 is a premium full synthetic motor oil formulated employing the latest additive technology to provide the ultimate protection for your engine. It is designed to deliver increased fuel efficiency and deposit protection even under severe service conditions. This engine oil meets the performance requirements of American, Japanese or European gasoline or diesel-fueled passenger cars, light trucks and sport utility vehicles, including gasoline-electric hybrids. FRAM Engine Oil Full Synthetic SAE 0W-40 exceeds the demanding engine performance requirements of today’s modern, higher revving sports, performance, and luxury vehicles. It helps maximize engine performance and improve engine efficiency while protecting turbochargers and emission control system catalysts. FRAM Engine Oil Full Synthetic 0W-40 meets the requirements of ACEA A3/B4 and API SP.

Product Features:
  • Exceptional Film Strength.
  • Excellent Protection for Metal Components from Rust, Corrosion and Wear.
  • Superior Oxidation Stability.
  • Outstanding Shear Stability.
  • Improved fuel economy.
  • Reduces fuel costs without sacrificing engine protection.
  • LSPI (Low Speed Pre-Ignition) Protection Throughout the Drain Interval.
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE OIL FOR YOUR ENGINE.
  • Ultimate Engine Protection: Formulated with the latest additive technology, FRAM Engine Oil Full Synthetic SAE 0W-40 provides superior protection for your engine, ensuring longevity and reliability.
  • Superior Performance Under Severe Conditions: This engine oil offers exceptional deposit protection and performance even under severe service conditions, making it ideal for high-stress driving environments.
  • Versatile Compatibility: Meets the performance requirements of American, Japanese, and European gasoline or diesel-fueled passenger cars, light trucks, sport utility vehicles, and gasoline-electric hybrids.
  • Exceeds Modern Engine Standards: Exceeds the demanding engine performance requirements of today’s modern, higher revving sports, performance, and luxury vehicles, while also protecting turbochargers and emission control system catalysts.
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Valvoline – European Vehicle 5W-30 Full Synthetic Motor Oil, Ultimate Protection, 5 Gallon (Part No.881058)

European Vehicle 5W-30 Full Synthetic Motor Oil, Ultimate Protection, 5 Gallon

from

$154.99
Valvoline European Vehicle Full Synthetic motor oil is specially formulated to provide the ultimate protection for European gas and diesel engines. Through its advanced formulation, Valvoline European Vehicle Full Synthetic provides extra detergents and dispersants that provide maximum sludge and deposit protection, along with premium additives that hold up to high temperatures and resist motor oil breakdown under severe driving conditions. Approved/ Licensed for most European applications including VW, BMW, Mercedes-Benz, Audi and Porsche vehicles.

Product Features:


Product Features:
  • Full synthetic formula for exceptional high and low temperature protection
  • Extra wear protection designed to keep engine parts like new
  • Extra detergents fight sludge and deposits that reduce engine life
  • American Owned and Operated
  • Approved for use in a wide range of European vehicles, including VW, BMW, Mercedes-Benz, Audi, and Porsche, ensuring compatibility with premium automotive brands.
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LIQUI MOLY – Top Tec 6600 0W-20 Full Synthetic Motor Oil, Improves Engine Efficiency, 5 Liter (Part No.22046)

Top Tec 6600 0W-20 Full Synthetic Motor Oil, Improves Engine Efficiency, 5 Liter

from

$68.99
Top Tec 6600 0W-20 Full Synthetic Motor Oil is engineered for superior performance and efficiency. Its low-friction, fully synthetic formula ensures smooth engine operation, outstanding cleanliness, and excellent wear protection. The 0W-20 viscosity grade delivers exceptional cold start performance, enhancing engine efficiency while reducing fuel consumption. Designed with innovative additive technology, this oil provides high lubrication reliability, greater oxidation stability, and extended engine life. Ideal for use with extended oil change intervals as recommended by the manufacturer, it offers unmatched value for modern engines. Perfectly suited for drivers seeking top-tier protection and performance in a 5-liter package.

Product Features:


Product Features:
  • Smooth engine running
  • Outstanding engine cleanliness
  • Excellent wear protection
  • High lubrication reliability
  • Enhanced cold start performance for improved engine efficiency and reduced fuel consumption.
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Mobil 1 – ESP 0W-30 Full Synthetic Motor Oil, Reduces Oil Aging, 5 Quart (Part No.47115)

ESP 0W-30 Full Synthetic Motor Oil, Reduces Oil Aging, 5 Quart

from

$37.99
Mobil 1 ESP 0W-30 is an advanced full synthetic oil specially formulated for passenger car diesels that have the latest diesel particulate filters (DPFs) and gasoline catalytic converters (CATs). The proprietary full synthetic motor oil is designed to help deliver outstanding performance and protection in conjunction with potential fuel economy benefits. Mobil 1 ESP has active cleaning agents that help to reduce deposits and sludge buildup for a cleaner engine. Helps to reduce oil aging with outstanding oxidation stability for extended drain interval protection. Low ash, sulfur, and phosphorous content help to reduce particulate buildup in DPFs and reduce poisoning of CATs. Excellent low temperature capabilities for quick cold-weather starting and ultra-fast protection. Mobil 1 is America’s leading synthetic motor oil brand at retail, recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR. (Source: The NPD Group/ Retail Tracking Service/ Dollar Sales/ PCMO Full Synthetic/ 52 weeks ending July 1, 2023)

Product Features:
  • Mobil 1 esp 0w-30 full synthetic oil is formulated for passenger car diesels with diesel particulate filters (dpfs ) and gasoline catalytic converters (CATs).
  • Low ash, sulfur, and phosphorous content help to reduce particulate build up in DPFs
  • Active cleaning agents that help to reduce deposits and sludge buildup for a cleaner engine
  • Helps to reduce oil aging with outstanding oxidation stability for extended drain interval protection
  • Excellent low temperature capabilities for quick cold-weather starting and ultra-fast protection
  • Manufacturer part number: 126609
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LIQUI MOLY – Top Tec 6600 0W-20 Full Synthetic Motor Oil, Improves Engine Efficiency, 1 Liter (Part No.22044)

Top Tec 6600 0W-20 Full Synthetic Motor Oil, Improves Engine Efficiency, 1 Liter

from

$20.49
Top Tec 6600 0W-20 Full Synthetic Motor Oil is engineered for superior performance, offering low friction and exceptional cold start behavior to enhance engine efficiency and reduce fuel consumption. Its advanced additive technology ensures outstanding wear protection, superb engine cleanliness, and greater oxidation stability, making it ideal for modern engines. With a low viscosity formula, this motor oil promotes smooth engine running and high lubrication reliability, even under demanding conditions. Designed for use with extended oil change intervals as specified by the manufacturer, it delivers long-lasting value and optimal engine care. Perfect for drivers seeking reliability and efficiency, this 1-liter solution is a smart choice for maintaining peak engine performance.

Product Features:


Product Features:
  • Smooth engine running
  • Outstanding engine cleanliness
  • Excellent wear protection
  • High lubrication reliability
  • Enhanced cold start performance for improved engine efficiency and reduced fuel consumption.
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LIQUI MOLY – Top Tec 0W-30 Full Synthetic Motor Oil, Highest Fuel Economy, 1 Liter (Part No.22156)

Top Tec 0W-30 Full Synthetic Motor Oil, Highest Fuel Economy, 1 Liter

from

$19.49
Top Tec 0W-30 Full Synthetic Motor Oil is engineered to deliver exceptional performance and efficiency for your engine. This low-SAPS motor oil minimizes friction, ensuring the highest fuel economy while providing optimum lubrication under all operating conditions. Its full synthetic composition and 0W-30 SAE weight make it ideal for extended oil change intervals, as recommended by manufacturers. Designed for compatibility with numerous Volkswagen and Audi vehicles, it is also suitable for select BMW diesel, Mercedes-Benz, and specific Porsche models. Whether you’re driving in extreme temperatures or under heavy loads, this oil ensures your engine operates at peak efficiency, offering long-lasting protection and reliability. Choose this premium motor oil for unmatched durability and value, keeping your engine running smoothly mile after mile.

Product Features:


Product Features:
  • Minimizes friction
  • Highest fuel economy
  • Optimum lubrication under all operating conditions
  • Compatible with a wide range of premium vehicle brands, ensuring versatility and reliability for diverse engine types.
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Mobil 1 – ESP X2 0W-20 Full Synthetic Motor Oil, Reduces Deposits & Sludge, 1 Quart (Part No.47114)

ESP X2 0W-20 Full Synthetic Motor Oil, Reduces Deposits & Sludge, 1 Quart

from

$11.99
Mobil 1 ESP X2 full synthetic motor oil 0W-20 is designed to provide outstanding engine cleanliness, wear protection, and advanced fuel economy (1) to keep your engine running like new. This proprietary motor oil has been engineered to help prolong the life and maintain the efficiency of emission systems in new emerging diesel and gasoline-powered European vehicles that require SAE 0W-20 viscosity grades. Mobil 1 ESP has active cleaning agents that help to reduce deposits and sludge buildup for a cleaner engine. This technologically advanced formula helps to reduce oil aging with excellent oxidation stability for extended oil drain interval protection and offers low-temperature protection for quick cold-weather starting and ultra-fast protection. Mobil 1 ESP X2 0W-20 combines durability and protection with a low viscosity, low friction motor oil that was designed in cooperation with key European Original Equipment Manufacturers (OEMs). Mobil 1 is America’s leading synthetic motor oil brand at retail (1) , recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR. To learn about the Mobil 1 Limited Warranty, visit Mobil.US. ((1) Compared to Mobil 1 ESP Formula 5W-30. (2) Source: The NPD Group/ Retail Tracking Service/ Dollar Sales/ PCMO Full Synthetic/ 52 weeks ending July 1, 2023)

Product Features:
  • Mobil 1 ESP 0W-20 full synthetic oil is formulated for passenger car diesels with diesel particulate filters (DPFs) and gasoline catalytic converters (CATs).
  • Engineered to help prolong the life and maintain the efficiency of emission systems in diesel and gasoline-powered European vehicles
  • Low viscosity, low friction motor oil designed with key European Original Equipment Manufacturers to ensure durability and protection
  • Active cleaning agents that help to reduce deposits and sludge buildup for a cleaner engines
  • Excellent low temperature protection for quick cold-weather starting and ultra-fast protection
  • Manufacturer Part Number: 125386
  • Outstanding Engine Cleanliness and Wear Protection: Mobil 1 ESP X2 0W-20 is designed to keep your engine running like new by providing exceptional engine cleanliness and wear protection.
  • Advanced Fuel Economy: This full synthetic motor oil helps improve fuel economy, making it an efficient choice for your vehicle.
  • Excellent Oxidation Stability: The advanced formula helps reduce oil aging with excellent oxidation stability, allowing for extended oil drain intervals and providing low-temperature protection for quick cold-weather starts.
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FAQs for 2022 Mercedes-Benz E350 Engine Oils

Which Engine Oils are the top sellers for the 2022 Mercedes-Benz E350?

Out of 8 Engine Oils that fit 2022 Mercedes-Benz E350s, the following parts are the top sellers:
0W-40 Full Synthetic Motor Oil, Exceptional Film Strength, 1 Quart
from $7.49
This product is not rated
0W-40 Full Synthetic Motor Oil, Exceptional Film Strength, 1 Quart
Engine Oil
Top Tec 0W-30 Full Synthetic Motor Oil, Highest Fuel Economy, 1 Liter
from $19.49
This product is not rated
Top Tec 0W-30 Full Synthetic Motor Oil, Highest Fuel Economy, 1 Liter
Engine Oil

How can I make sure that a part will be compatible with my 2022 Mercedes-Benz E350?

Our Mercedes-Benz E350 aftermarket and OEM parts are designed specifically for the 2022 model. You can always find your specific fitment and compatibility for your 2022 Mercedes-Benz on an individual product page.

What is the price range for 2022 Mercedes-Benz E350 Engine Oils?

The range of prices of Engine Oils for the 2022 Mercedes-Benz E350 goes from $7.49 up to $154.99 for the most premium parts.

What is the average price of 2022 Mercedes-Benz E350 Engine Oils?

2022 Mercedes-Benz E350 Engine Oils average $41.68 for our selection of OEM and aftermarket parts.

Does Advance Auto Parts sell Engine Oils for other Mercedes-Benz E350 model years?

Yes, we currently stock Engine Oils for 13 model years of Mercedes-Benz E350s, from 2006 to 2023. Model years 2023, 2021, 2020, 2016, 2015, 2014, 2013, 2012, and 2011 are the most popular for Engine Oils purchases.

Can I get help with 2022 Mercedes-Benz E350 Engine Oils orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Engine Oils and more.

What is your return policy for Mercedes-Benz E350 Engine Oils?

Advance Auto Parts keeps returns simple. For new Mercedes-Benz E350 Engine Oils and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.