2022 Mercedes-Benz E350 Cooling and Climate Controls
Find Your Specific 2022 Mercedes-Benz E350 Cooling and Climate Controls
Below you will find various in-demand Mercedes-Benz Cooling and Climate Controls, components and accessories for your 2022 E350. Advance Auto Parts has popular E350 parts like Engine Cooling Parts Air Conditioning Parts and more. You’ll also find aftermarket and OEM Cooling and Climate Controls for other E350 model years including
2011,
2012,
2013,
2014,
2015,
2016,
2020,
2021,
2023 and more. Select a category of 2022 Mercedes-Benz E350 Cooling and Climate Controls below and start saving instantly.
Popular 2022 Mercedes-Benz E350 Cooling and Climate Controls Categories
Essential Cooling and Climate Controls for 2022 Mercedes-Benz E350s
Dorman – Pressurized Coolant Reservoir: Black And Clear, Plastic, Original Equipment Replacement (Part No.603-257)
from
$61.99
This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part.
Product Features:
See More
Product Features:
- Direct replacement – this engine coolant reservoir matches the fit and function of the original part.
- Ideal solution – engineered for a seamless installation.
- Durable construction – manufactured from quality materials to withstand underhood heat and vibration
- Trustworthy design – backed by 100 years of automotive aftermarket experience
Behr – Behr Expansion Tank (Part No.G1030461987BEH)
from
$54.53
The Behr expansion tank is made of the highest quality materials and is engineered to meet or exceed the OEM specifications for performance, fit and durability.
Product Features:
See More
Product Features:
- OE-Equivalent and Direct Fit for easy Installation.
- OE style connections and fittings.
- Made of highly durable materials.
- Resistant to thermal wear and cracking.
Carquest Premium – Coolant Temperature Sensor with O-Ring and Install Clip (Part No.WTC1122)
from
$19.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.
Product Features:
See More
Product Features:
- 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
- Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
- Brass sensor housing precision machined to meet or exceed OE thermal conductivity
- OE precision matched thermistor position for correct output parameters
- Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
Carquest Premium – A/C New, with Clutch, with 6SEU16C Compressor (Part No.T198379)
from
$409.99
Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.
Product Features:
See More
Product Features:
- Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
- New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
- The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
- All new compressors must pass a helium leak test and pump up function test prior to packaging.
- O-Rings and gaskets necessary for installation are included.
Carquest Premium – New Compressor with Clutch, Nippondenso 6SAS14C (Part No.T168324)
from
$448.99
High quality OE replacement part with all components needed to complete the job
Product Features:
See More
Product Features:
- Endurance tested the equivalent of 50k miles
- Includes specific electrical connector to eliminate splicing
- Charged with lubricant to reduce internal friction promoting enhanced system performance and longevity
- For ease of installation this compressor includes a direct fit OE style connector as well as all gaskets, O-rings, or seals needed to repair your car
- Each unit is individually leak, vacuum and pressure tested prior to packaging to ensure leak free performance
ACM – A/C Schrader Valve C (Part No.R1138570550ACM)
from
$2.92
A/C Schrader Valve C
Carquest Premium – A/C Filter Drier with Pad Mount (Part No.T83358)
from
$54.99
Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.
Product Features:
See More
Product Features:
- All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
- Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
- All accumulators and receiver driers are helium leak tested prior to packaging.
- O-Rings necessary for installation are included.
ACM – A/C Receiver Drier (Part No.R1040148374ACM)
from
$70.15
The ACM A/C Receiver Drier is manufactured to exact OEM specifications for quality fit and performance.
Product Features:
See More
Product Features:
- OE-Equivalent and Direct fit Application.
- Meets or exceeds the vehicle manufacturer specifications.
- Utilizes factory style fittings and connectors.
- Includes the required o-rings and associated hardware
Santech – A/C Schrader Valve C (Part No.R1138570551SII)
from
$8.05
A/C Schrader Valve C
Carquest Premium – Engine Coolant Reservoir Cap (Part No.10253)
from
$19.79
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.
Product Features:
See More
Product Features:
- Maintains proper cooling system pressure
- Easy installation and removal
- 100% tested to ensure proper pressure and longevity
- Meets all OEM specifications
Rein – Cap-Expansion Tank (Part No.CPE0029P)
from
$29.99
Rein Automotive OE Quality expansion tank caps are designed to be direct replacements for OE caps. Rein caps are designed to match or exceed the OE materials used and are produced to the highest standards to ensure long service life. Rein Automotive OE quality expansion tank caps keep the coolant system at the proper pressure just like the OE cap.
Product Features:
See More
Product Features:
- Manufactured to strict engineering standards/specifications in materials and tolerances.
- Direct fit.
- Meets or exceeds pressure specifications demanded by the OE manufacturer.
- Produced by an original equipment supplier.
ACM – Air Conditioning Evaporator Temperature Sensor (Part No.R1071421726ACM)
DENSO – First Time Fit A/C Conr (Part No.R1030270292ND)
from
$279.51
Like all DENSO First Time Fit® A/C components, our condensers are designed and manufactured to integrate seamlessly with the vehicle’s original air conditioning system. DENSO condensers match up to OE condensers at every benchmark. Multiflow, subcooling, and the latest Ssrpentine condenser styles are offered to provide the optimum configuration for each application. Premium aluminum construction improves reliability, resisting corrosion to avoid expensive system leaks, while the superior fin wave design offers higher heat transfer and maximum refrigerant condensation. Heat exchanger cores are specially designed to shed airborne material buildup, allowing the A/C system to operate at peak efficiency with minimal maintenance, assuring years of trouble-free service.
Product Features:
See More
Product Features:
- Zinc diffusion layer improves corrosion resistance
- Unique fin design to minimize airflow blockage
- High performance design reduces the required compressor power
- System Efficiency: Superior fin waves provide a higher heat transfer coefficient and full condensation.
- Engineered to Perfection: OE quality engineered for unparalleled performance
- Exact Fit: Condensers install with speed and ease
- Reduces required compressor power, resulting improved fuel economy
- Restores A/C performance to as-new condition
- First Time Fit® assures bolt-in replacement; no brackets or adapters
- Greater Durability: Pure aluminum construction provides greater resistance for corrosion
Nissens – Nissens A/C Condenser (Part No.R1030401132NSS)
from
$201.39
Nissens manufactures an A/C Condenser that is the same quality fit and performance of the OE Condenser it replaces.
Product Features:
See More
Product Features:
- OEM Quality Direct fit Application
- Utilizes fixed feeder tubes with no fault tolerance in length, diameter and bending angle, providing protection against leaks and loss of efficiency.
ACM – A/C Condenser (Part No.R1030401132ACM)
from
$304.04
The ACM A/C Condenser is manufactured to exact OEM specifications for quality fit and performance.
Product Features:
See More
Product Features:
- OE-Equivalent and Direct fit Application.
- Meet or exceed OEM specifications.
- Utilizes the factory style mounts, connectors and fittings.
- Compatible with R12 and R134a refrigerant.
- Applicable gaskets and O-rings supplied with each part.
Febi – Rivet (Part No.Q20011324407FEB)
from
$2.02
Rivet
ACM – Air Conditioning Pressure Switch (Part No.R1054445297ACM)
from
$69.77
ACM is a supplier of Original Equipment quality climate control products. 3 pin connector
See More
Rein – Radiator Mount (Part No.AVM0699)
from
$19.99
Anti-vibration parts dampen vibration harmonics from the engine and drive line components to rest of the vehicle. This in turn reduces vibration and noise which can be felt and heard while the vehicle is in operation. Rein Automotive anti-vibration parts are application specific and match the design and function of the OE parts.
Product Features:
See More
Product Features:
- Rubber components match the shore hardness of the original equipment bushing to ensure maximum performance and product longevity.
- Part has a high corrosion resistance for maximum life.
- Produced with high quality materials to ensure maximum life and a smooth ride.
- Made by the OE manufacturer.
Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA2004)
from
$41.99
The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.
Product Features:
See More
Product Features:
- Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
- Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
- All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
- All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging
Upgrade your 2022 Mercedes-Benz E350 with Top-Quality Cooling and Climate Controls
When it comes to maintaining or upgrading your 2022 Mercedes-Benz E350, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Mercedes-Benz or enhancing its overall performance, Cooling and Climate Controls are key to keeping your E350 functioning at its best. At Advance Auto Parts, we offer a wide selection of 17 Cooling and Climate Controls for the 2022 Mercedes-Benz E350, designed to meet your needs without breaking the bank.
From
Engine Cooling Part
replacements to
Air Conditioning Parts
upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.
Affordable Prices and Wide Selection
Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2022 Mercedes-Benz E350 at great prices.
Our Cooling and Climate Controls inventory for this model
ranges from just $2.92 to $448.99, with
an average price of $80.90.
Our 17 Cooling and Climate Controls in stock come from 9 trusted brands, so you’re sure to find the right part for your 2022 Mercedes-Benz E350 without overspending.
Explore Related Parts and More
While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Oil and Lubricants, Fluids and Chemicals
and more to make sure your 2022 Mercedes-Benz E350 is always ready to roll. We’re committed to providing you with everything you need to keep your E350 in top shape, all in one place.
Start shopping confidently below for your 2022 Mercedes-Benz E350!
Best-Selling Engine Cooling Parts for 2022 Mercedes-Benz E350s
Enhance the driving experience in your Mercedes-Benz with 7 quality Engine Cooling Part components, starting at $2.92.
Rein – Coolant Expansion Tank (Part No.G1030948962RIN)
from
$69.82
The Rein Engine Coolant Recovery Tank is designed for enduring use. It resists the expansion and cracking that extreme temperature fluctuations can cause. Plus, the virgin plastic construction prevents coolant fluid loss.
Product Features:
See More
Product Features:
- Includes Sensor and OE Cap (if applicable)
- Produced from virgin plastic meeting/exceeding OE specifications, ensuring long life
- Resistant to cracking and wear from heat cycles preventing coolant loss
- Direct fitment allows easy installation
Rein – Cap-Expansion Tank (Part No.CPE0029P)
from
$29.99
Rein Automotive OE Quality expansion tank caps are designed to be direct replacements for OE caps. Rein caps are designed to match or exceed the OE materials used and are produced to the highest standards to ensure long service life. Rein Automotive OE quality expansion tank caps keep the coolant system at the proper pressure just like the OE cap.
Product Features:
See More
Product Features:
- Manufactured to strict engineering standards/specifications in materials and tolerances.
- Direct fit.
- Meets or exceeds pressure specifications demanded by the OE manufacturer.
- Produced by an original equipment supplier.
Worldpac – EXPANSION TANK CAP (Part No.G10403566322BEH)
from
$20.03
EXPANSION TANK CAP
Rein – Radiator Mount (Part No.AVM0699)
from
$19.99
Anti-vibration parts dampen vibration harmonics from the engine and drive line components to rest of the vehicle. This in turn reduces vibration and noise which can be felt and heard while the vehicle is in operation. Rein Automotive anti-vibration parts are application specific and match the design and function of the OE parts.
Product Features:
See More
Product Features:
- Rubber components match the shore hardness of the original equipment bushing to ensure maximum performance and product longevity.
- Part has a high corrosion resistance for maximum life.
- Produced with high quality materials to ensure maximum life and a smooth ride.
- Made by the OE manufacturer.
Worldpac – WATER TEMP. SENSOR (Part No.C6020656996FAE)
from
$15.79
WATER TEMP. SENSOR
Febi – Radiator Mount (Part No.G10201334012FEB)
from
$9.76
Radiator Mount
Febi – Rivet (Part No.Q2001721547FEB)
from
$2.92
Rivet
Most Popular 2022 Mercedes-Benz E350 Air Conditioning Parts
Customize your Mercedes-Benz with 10 Air Conditioning Parts products
like AC Compressor With Clutch,
AC Condensers, and
Accumulator and Receiver Driers, all
priced under $448.99.
ACM – Air Conditioning Pressure Switch (Part No.R1054445297ACM)
from
$69.77
ACM is a supplier of Original Equipment quality climate control products. 3 pin connector
See More
Behr – A/C Condenser (Part No.R1030661038BEH)
from
$234.66
BEHR manufactures an OE-equivalent direct fit A/C Condenser that guarantees the same high quality, fit and performance of the OEM A/C condenser it replaces. BEHR produces brazed flat-tube condensers, delivering high power in spite of their small package size. This ensures rapid cooling of the vehicle cabin, thanks to optimum matching of heat transfer and pressure drop on the coolant side and air side.
Product Features:
See More
Product Features:
- OE-Equivalent and Direct fit Application.
- Advanced technology parallel flow, sub cool and serpentine design.
- Provides the fit, quality and performance of the original equipment.
- compliant for both R12 and R134A refrigerants.
Carquest Premium – New Compressor with Clutch, Nippondenso 6SAS14C (Part No.T168324)
from
$448.99
High quality OE replacement part with all components needed to complete the job
Product Features:
See More
Product Features:
- Endurance tested the equivalent of 50k miles
- Includes specific electrical connector to eliminate splicing
- Charged with lubricant to reduce internal friction promoting enhanced system performance and longevity
- For ease of installation this compressor includes a direct fit OE style connector as well as all gaskets, O-rings, or seals needed to repair your car
- Each unit is individually leak, vacuum and pressure tested prior to packaging to ensure leak free performance
Nissens – A/C Condenser (Part No.R1030926912NSS)
from
$271.20
Nissens manufactures an A/C Condenser that is the same quality fit and performance of the OE Condenser it replaces.
Product Features:
See More
Product Features:
- OEM Quality Direct fit Application
- Utilizes fixed feeder tubes with no fault tolerance in length, diameter and bending angle, providing protection against leaks and loss of efficiency.
KAI – A/C Condenser (Part No.CND4742)
from
$78.99
New Platinum Pro A/C Condenser
Product Features:
See More
Product Features:
- Made Of Aluminum
- Meets All Federal Motor Safety Standards
- No Drilling Needed For Installation
- No Modifications Needed For Installation
- Direct Fit Replacement For Your Vehicle
- Same Form Fit And Function As OE
- Check Out The Large Selection Of Parts Available For Your Vehicle
Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA2004)
from
$41.99
The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.
Product Features:
See More
Product Features:
- Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
- Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
- All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
- All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging
Carquest Premium – A/C Desiccant Bag Kit (Part No.T83380)
from
$29.99
Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.
Product Features:
See More
Product Features:
- All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
- Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
- All accumulators and receiver driers are helium leak tested prior to packaging.
- O-Rings necessary for installation are included.
ACM – Air Conditioning Evaporator Temperature Sensor (Part No.R1071421726ACM)
Santech – A/C Schrader Valve C (Part No.R1138570551SII)
from
$8.05
A/C Schrader Valve C
ACM – A/C Schrader Valve C (Part No.R1138570550ACM)
from
$2.92
A/C Schrader Valve C
FAQs for 2022 Mercedes-Benz E350 Cooling and Climate Controls
Which Cooling and Climate Controls are best-sellers for 2022 Mercedes-Benz E350s?
Out of 17 Cooling and Climate Controls that fit 2022 Mercedes-Benz E350s, the following parts are the top sellers:
- Air Conditioning Pressure Switch (10766886) – $69.77
- A/C Condenser (12049727) – $234.66
- A/C Condenser (11718313) – $78.99
What’s the price range for 2022 Mercedes-Benz E350 Cooling and Climate Controls?
Cooling and Climate Control prices for the 2022 Mercedes-Benz E350 start at $2.92 and go up to $448.99 for the most premium parts.
What’s the average price of a Cooling and Climate Control for a 2022 Mercedes-Benz E350?
The average price for Cooling and Climate Controls for the 2022 Mercedes-Benz E350 is $80.90. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Cooling and Climate Controls for other Mercedes-Benz E350 model years?
What are the cheapest Cooling and Climate Controls for my 2022 Mercedes-Benz E350?
The cheapest 2022 Mercedes-Benz E350 Cooling and Climate Controls we carry in stock are:
- Rivet (11990827) – $2.92
- A/C Schrader Valve C (11591429) – $2.92
- A/C Schrader Valve C (11591057) – $8.05
- Radiator Mount (12485838) – $9.76
- WATER TEMP. SENSOR (50222417) – $15.79
What types of Cooling and Climate Controls do you sell for my 2022 Mercedes-Benz E350?
As of 2/5/25, these are some of the most in-demand types of Cooling and Climate Controls for a 2022 Mercedes-Benz E350:
Can I get help with 2022 Mercedes-Benz E350 Cooling and Climate Control orders?
Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Cooling and Climate Controls and more.
What is your return policy for Mercedes-Benz E350 Cooling and Climate Controls?
Advance Auto Parts keeps returns simple. For new Mercedes-Benz E350 Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.
