2022 Lexus IS300 Cooling and Climate Controls

Below you will find various in-demand Lexus Cooling and Climate Controls, components and accessories for your 2022 IS300. Advance Auto Parts has popular IS300 parts like Engine Cooling Parts, Blower Motor and Related Products, Air Conditioning Parts and more. You’ll also find aftermarket and OEM Cooling and Climate Controls for other IS300 model years including 2004, 2005, 2016, 2017, 2018, 2019, 2020, 2021, 2023 and more. Select a category of 2022 Lexus IS300 Cooling and Climate Controls below and start saving instantly.

Please Select your Vehicle to See Exact Fit Parts

Popular 2022 Lexus IS300 Cooling and Climate Controls Categories

Radiators

AC Compressor With Clutch

Blower Motors

Thermostats

Radiator Fan Motors

Coolant Temperature Sensors

Coolant Reservoir Caps

Air Conditioning Relays

Accumulator and Receiver Driers

AC Refrigerant Pressure Sensors

Essential Cooling and Climate Controls for 2022 Lexus IS300s

from

$21.99

Relay

Product Features:

Lifecycle lasts up to 10 times longer than the competitor’s
Flux free micro arc welding versus competitors that solder
High conductive material that does not corrode
Shortest path for the electrical current improves efficiency
Offered by world’s largest relay manufacturer

from

$21.99

Relays are electrical switches used to convert a small electrical load into a circuit capable of handling a high amperage load. Computers and small switches are not designed to carry the higher amperage requirement of a circuit that may have an electric motor, solenoid, or high amperage lighting fixture. Within a relay are contacts that are controlled with electromagnetism, when the circuit switch commands the device on or off, magnetism will pull or release the contact arm closing or opening the contacts within the relay that carry the voltage.

Product Features:

Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
100% end-of-line tested to ensure accurate signal output providing product reliability, every time.

from

$10.99

Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:

Maintains proper cooling system pressure
Easy installation and removal
100% tested to ensure proper pressure and longevity
Meets all OEM specifications

from

$114.99

Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$17.29

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$64.99

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$511.99

New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications.

Product Features:

Every unit is 100% function and leak tested
Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
Very low friction coating used on swash plate to improve durability
PTFE coated pistons improve performance and reduce wear
Rubber dampened clutch plate ensures smooth clutch engagement and reduces wear
Matched high-quality needle-roller bearing ensures low friction and high load capability
Limited Warranty when following warranty requirements: Flush A/C System, replace accumulator/receiver dryer, replace orifice tube/expansion device, and filling with correct oil and refrigerant
New Compressors meet or exceed OE specifications
New Compressors are validated for the equivalent of 100,000 miles
New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications
New Compressors come with direct fit connectors for ease of installation and to help eliminate splicing
New Compressors come with the R12/R134A/1234yf required O-rings /sealing washers to install the compressor

from

$615.99

Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.

Product Features:

Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
All new compressors must pass a helium leak test and pump up function test prior to packaging.
O-Rings and gaskets necessary for installation are included.

from

$722.99

As one of the world’s largest OE suppliers of A/C compressors DENSO units are specified by most major vehicle manufacturers. DENSO First Time Fit A/C compressors are manufactured and tested to the strictest OE standards for unparalleled performance. At DENSO we bring together everything we know as an air conditioning systems manufacturer to bring you the highest quality line of factory-new compressors available. When it comes to new compressors you can’t do better than going with a unit manufactured by the OE supplier. At DENSO we know these units better than anyone because we originally designed them. Our compressors are built to meet DENSO’s unsurpassed reputation for technological superiority. You can relax knowing DENSO will give you the right part and the right fit the first time.

Product Features:

DENSO is the world’s largest OE supplier of A/C compressors
Each compressor is precision manufactured for exact replacement
Designed for high output and extended durability
Highest quality in the Aftermarket

from

$453.99

This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:

Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
Complete package – assembly is designed with the same materials and components as the original part
Quality assured – motors are tested in laboratory settings to ensure performance
Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership

from

$23.99

Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:

All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
All accumulators and receiver driers are helium leak tested prior to packaging.
O-Rings necessary for installation are included.

from

$156.99

Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor

from

$347.99

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Functionally Equivalent to OE Design
Magnetic size and properties compare or exceed OEM
Hermetically Sealed & Thermally Protected Electronics

from

$32.99

Carquest Premium coolant temperature sensors and switches are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry, Carquest Premium coolant temperature sensors and switches undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium coolant temperature sensors and switches are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:

Designed to meet or exceed OE specifications for fit, form and function
100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
OE precision matched thermistor ensuring sensors match OE output resistances across all temperature positions
O-rings, seals or thread sealant are included if required
Weather-tight connectors prevent leaks and corrosion for longer life
Extensive design validation testing and 100% end-of-line tested
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

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$34.05

High quality OE replacement part with all components needed to complete the job

Product Features:

Contains gaskets, O-rings, or seals to properly replace the product
Brass construction for accurate temperature sensing
Color coded for easy identification
Zinc coated terminal to resist corrosion

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$65.99

Product Features:

Designed to meet or exceed OE specifications for fit, form and function
100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
O-rings, seals or thread sealant are included if required
Weather-tight connectors prevent leaks and corrosion for longer life
Extensive design validation testing and 100% end-of-line tested
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$41.49

Delphi’s history is one of OE heritage and quality. Our global technical requirements include design specifications and validation testing based on over 100 years of OE experience. Our material selections, material thickness, and material types are built from OE specifications to exceed aftermarket expectations. We put in place strict manufacturing processes to ensure quality control in every part we make. Delphi’s pioneering spirit delivers innovative solutions designed to support the aftermarket in servicing the vehicles of today, and tomorrow.

Product Features:

Delphi temperature sensors deliver accurate readings and optimal performance
Delphi’s 1 piece design and automated production process eliminates internal connectors and failure points
Each sensor is electrically insulated to eliminate interference from other components in the vehicle
Delphi temperature sensors are impervious to electrical noise and interference

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$36.99

TEMPERATURE SENSOR

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$128.99

The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:

Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
All units are tested using automated end-of-line testing equipment that pressurizes the sensor and checks full-spectrum functionality and electrical output to ensure each part meets manufacturing specifications before packaging.

from

$297.99

Carquest Premium Radiators offer one of the largest product ranges in the aftermarket, covering more than 95% of the popular automotive and light truck applications. Carquest Premium Radiators meet or exceed original equipment specifications, ensuring that products fit and perform just as well or better than the original parts, providing you peace of mind.

Product Features:

Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
Our fin edges are folded for increased stability and heat disbursement properties.
Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.

from

$285.99

Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
Our fin edges are folded for increased stability and heat disbursement properties.
Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.

from

$178.99

Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
Our fin edges are folded for increased stability and heat disbursement properties.
Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.

Upgrade your 2022 Lexus IS300 with Top-Quality Cooling and Climate Controls

When it comes to maintaining or upgrading your 2022 Lexus IS300, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Cooling and Climate Controls are key to keeping your IS300 functioning at its best. At Advance Auto Parts, we offer a wide selection of 16 Cooling and Climate Controls for the 2022 Lexus IS300, designed to meet your needs without breaking the bank. From Engine Cooling Part replacements to Blower Motor and Related Products upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2022 Lexus IS300 at great prices. Our Cooling and Climate Controls inventory for this model ranges from just $10.99 to $511.99, with an average price of $154.04. Our 16 Cooling and Climate Controls in stock come from 4 trusted brands, so you’re sure to find the right part for your 2022 Lexus IS300 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2022 Lexus IS300, we stock popular OEM and aftermarket Cooling and Climate Controls from top names like Carquest Premium, and more. Carquest Premium Cooling and Climate Controls start at just $10.99 and boast an impressive 4.4 stars average rating from customers. With 8 customer reviews and counting, our 2022 Lexus IS300 Cooling and Climate Controls have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2022 Lexus IS300 is always ready to roll. We’re committed to providing you with everything you need to keep your IS300 in top shape, all in one place. Start shopping confidently below for your 2022 Lexus IS300!

Best-Selling Engine Cooling Parts for 2022 Lexus IS300s

Enhance the driving experience in your Lexus with 11 quality Engine Cooling Part components, starting at $10.99.

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from

$10.99

Maintains proper cooling system pressure
Easy installation and removal
100% tested to ensure proper pressure and longevity
Meets all OEM specifications

from

$32.99

Designed to meet or exceed OE specifications for fit, form and function
100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
OE precision matched thermistor ensuring sensors match OE output resistances across all temperature positions
O-rings, seals or thread sealant are included if required
Weather-tight connectors prevent leaks and corrosion for longer life
Extensive design validation testing and 100% end-of-line tested
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$285.99

Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
Our fin edges are folded for increased stability and heat disbursement properties.
Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.

from

$453.99

Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
Complete package – assembly is designed with the same materials and components as the original part
Quality assured – motors are tested in laboratory settings to ensure performance
Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership

from

$317.99

A global leader in the manufacture and distribution of aftermarket cooling products for automotive, heavy truck, and industrial applications. Specialized in the production of OE-quality Radiators, Condensers, and Charge Air Coolers for US and international markets, covering over 10,000 part numbers worldwide. Reach Cooling is headquartered in Miami, Florida, with additional distribution centers in Los Angeles, California and a manufacturing plant in Shanghai, China.

Product Features:

Our B-type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
Our fin edges are folded for increased stability and heat disbursement properties.
Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Thermal expansion cuts allow for longer life and reduce failure rates by allowing improved core expansion and contraction during normal heat cycles.
We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.

from

$114.99

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$99.99

DENSO’s engine coolant temperatures sensors are manufactured to the strictest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.

Product Features:

OE technology adapted for the aftermarket
Reduces emissions, increased performance
Delivers the highest reliability and detection accuracy

from

$65.99

Product Features:

Designed to meet or exceed OE specifications for fit, form and function
100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
O-rings, seals or thread sealant are included if required
Weather-tight connectors prevent leaks and corrosion for longer life
Extensive design validation testing and 100% end-of-line tested
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$64.99

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$48.99

TEMPERATURE SENSOR

from

$36.99

TEMPERATURE SENSOR

Most Popular 2022 Lexus IS300 Blower Motor and Related Products

Customize your Lexus with 1 Blower Motor and Related Products products like Blower Motors, all priced under $347.99.

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from

$347.99

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Functionally Equivalent to OE Design
Magnetic size and properties compare or exceed OEM
Hermetically Sealed & Thermally Protected Electronics

Top Picks for 2022 Lexus IS300 Air Conditioning Parts

Upgrade Lexus IS300s with top-quality Air Conditioning Parts parts, including 4 OEM and aftermarket selections for your 2022 model.

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from

$21.99

Relay

Product Features:

Lifecycle lasts up to 10 times longer than the competitor’s
Flux free micro arc welding versus competitors that solder
High conductive material that does not corrode
Shortest path for the electrical current improves efficiency
Offered by world’s largest relay manufacturer

from

$128.99

Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
All units are tested using automated end-of-line testing equipment that pressurizes the sensor and checks full-spectrum functionality and electrical output to ensure each part meets manufacturing specifications before packaging.

from

$511.99

New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications.

Product Features:

Every unit is 100% function and leak tested
Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
Very low friction coating used on swash plate to improve durability
PTFE coated pistons improve performance and reduce wear
Rubber dampened clutch plate ensures smooth clutch engagement and reduces wear
Matched high-quality needle-roller bearing ensures low friction and high load capability
Limited Warranty when following warranty requirements: Flush A/C System, replace accumulator/receiver dryer, replace orifice tube/expansion device, and filling with correct oil and refrigerant
New Compressors meet or exceed OE specifications
New Compressors are validated for the equivalent of 100,000 miles
New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications
New Compressors come with direct fit connectors for ease of installation and to help eliminate splicing
New Compressors come with the R12/R134A/1234yf required O-rings /sealing washers to install the compressor

from

$23.99

All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
All accumulators and receiver driers are helium leak tested prior to packaging.
O-Rings necessary for installation are included.

Top-Rated Cooling and Climate Controls Brands For Your 2022 Lexus IS300

Shop for the best-rated brands offering Cooling and Climate Controls and other products for your 2022 Lexus IS300s. Below you’ll find some of our best rated Cooling and Climate Controls from Carquest Premium, and more. Cooling and Climate Controls from these brands that fit a 2022 IS300 start at just $10.99 and are rated as high as 4.4 stars. OEM and aftermarket Cooling and Climate Controls don’t get more top quality, durable, and affordable than from the brands below.

Popular Carquest Premium 2022 Lexus IS300 Cooling and Climate Controls

When it comes to maintaining or upgrading your 2022 Lexus IS300, using quality Cooling and Climate Controls is essential to ensure durability and a perfect fit. Carquest Premium ticks all of those boxes. We offer a wide selection of Carquest Premium Cooling and Climate Controls, specifically designed for the 2022 Lexus IS300. With over 1 Carquest Premium brand Cooling and Climate Controls in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $10.99. Plus, with over 4 customer reviews and an average rating of 4.4 stars, you can trust that our Carquest Premium Cooling and Climate Controls will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

from $10.99

(4)

Engine Coolant Reservoir Cap

“I had a difficult time finding a coolant reservoir cap for a Toyota Prius. Advance was the only place in town that carried them.”

FAQs for 2022 Lexus IS300 Cooling and Climate Controls

Which Cooling and Climate Controls are best-sellers for 2022 Lexus IS300s?

Out of 16 Cooling and Climate Controls that fit 2022 Lexus IS300s, the following parts are the top sellers:

Coolant Temperature Sensor (12422776) – $32.99
Relay (10129604) – $21.99
Air Conditioner Refrigerant Pressure Sensor (12541539) – $128.99

What’s the price range for 2022 Lexus IS300 Cooling and Climate Controls?

Cooling and Climate Control prices for the 2022 Lexus IS300 start at $10.99 and go up to $511.99 for the most premium parts.

What’s the average price of a Cooling and Climate Control for a 2022 Lexus IS300?

The average price for Cooling and Climate Controls for the 2022 Lexus IS300 is $154.04. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Cooling and Climate Controls for other Lexus IS300 model years?

Yes, we currently carry Cooling and Climate Controls for 13 model years of Lexus IS300s between 2001 and 2025. Cooling and Climate Controls are bought most frequently for the following model years: 2023, 2021, 2020, 2019, 2018, 2017, 2016, 2005, and 2004.

What are the cheapest Cooling and Climate Controls for my 2022 Lexus IS300?

The cheapest 2022 Lexus IS300 Cooling and Climate Controls we carry in stock are:

Engine Coolant Reservoir Cap (15480044) – $10.99
Relay (10129604) – $21.99
A/C Receiver Drier / Desiccant Element Header and Filter (11842042) – $23.99
Coolant Temperature Sensor (12422776) – $32.99
TEMPERATURE SENSOR (50260680) – $36.99

What are the top-rated Cooling and Climate Controls that fit the 2022 Lexus IS300?

Out of 8 reviews by customers, our 2022 Lexus IS300 Cooling and Climate Controls have an average customer rating of . These are some of the highest-rated Cooling and Climate Control types for the 2022 Lexus IS300 and their top-rated products:

Engine Cooling Parts
- Engine Coolant Reservoir Cap (15480044) – $10.99

What types of Cooling and Climate Controls do you sell for my 2022 Lexus IS300?

As of 3/1/26, these are some of the most in-demand types of Cooling and Climate Controls for a 2022 Lexus IS300:

Can I get help with 2022 Lexus IS300 Cooling and Climate Control orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Cooling and Climate Controls and more.

What is your return policy for Lexus IS300 Cooling and Climate Controls?

Advance Auto Parts keeps returns simple. For new Lexus IS300 Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2022 Lexus IS300 Cooling and Climate Controls

DENSO – Relay (Part No.567-0004)

Carquest Premium – Multi-Purpose Relay, 30 Amp (Part No.RAA1238)

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)

Carquest Premium – Standard Thermostat: 180 Degrees (Part No.1065-180)

Carquest Premium – Standard Thermostat: 180 Degrees (Part No.14108)

Carquest Premium – Standard Thermostat: 172 Degrees (Part No.1064-172)

Carquest Premium – New Compressor (Part No.T168367)

Carquest Premium – A/C Compressor, New, with Clutch, with 7SBU16H Compressor (Part No.T78371)

DENSO – A/C Compressor with Clutch – New (Part No.471-1361)

Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-498)

Carquest Premium – A/C Receiver Drier / Desiccant Element Header and Filter (Part No.T83233)

Carquest Premium – Blower Motor: with Wheel (Part No.76937)

Carquest Premium – Blower Motor: With Wheel (Part No.76526)

Carquest Premium – Coolant Temperature Sensor (Part No.WTC1005)

Factory Air – Coolant Temp Sensor Switch (Part No.36424)

Carquest Premium – Coolant Temperature Sensor 1TS1172 (Part No.WTC2071)

Delphi – Engine Coolant Temperature Sensor (Part No.TS10198)

AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8001)

Carquest Premium – Air Conditioner Refrigerant Pressure Sensor (Part No.ACA1745)

Carquest Premium – Radiator (Part No.432635)

Carquest Premium – Radiator (Part No.813612)

Carquest Premium – Radiator (Part No.813477)

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)

Carquest Premium – Coolant Temperature Sensor (Part No.WTC1005)

Carquest Premium – Radiator (Part No.813612)

Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-498)

Carquest Premium – Radiator (Part No.4113912)

Carquest Premium – Standard Thermostat: 180 Degrees (Part No.1065-180)

DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)

Carquest Premium – Coolant Temperature Sensor 1TS1172 (Part No.WTC2071)

Carquest Premium – Standard Thermostat: 172 Degrees (Part No.1064-172)

AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8003)

AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8001)

Carquest Premium – Blower Motor: With Wheel (Part No.76526)

DENSO – Relay (Part No.567-0004)

Carquest Premium – Air Conditioner Refrigerant Pressure Sensor (Part No.ACA1745)

Carquest Premium – New Compressor (Part No.T168367)

Carquest Premium – A/C Receiver Drier / Desiccant Element Header and Filter (Part No.T83233)