2022 GMC Sierra 2500 HD Drive Shafts and Axles
Keep Your 2022 GMC Sierra 2500 HD in Top Shape with Quality Drive Shafts and Axles
Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2022 GMC Sierra 2500 HD looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Axle Shaft Seals and Axle Flange Gaskets. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.
Competitive Prices and Extensive Inventory
The average price for a 2022 GMC Sierra 2500 HD Drive Shafts and Axle at Advance Auto Parts is around $40.74, with a range that starts at $21.49 and goes up to $59.99. With 2 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like Axle Shaft Seal and Axle Flange Gasket Kit start at just $21.49 and offer a great balance of form and function.
Explore Related Parts
While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Transfer Cases and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2022 GMC Sierra 2500 HD in peak condition, inside and out.
Find Your Specific 2022 GMC Sierra 2500 HD Drive Shafts and Axles
Looking for the perfect Drive Shafts and Axle for your 2022 GMC Sierra 2500 HD? You’re in the right place. Below, you’ll find links to various types of Drive Shafts and Axles that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Drive Shafts and Axles, ensuring durability and a precise fit for your GMC Sierra 2500 HD. Whether you’re driving a 2022 model or another popular model year like
2014,
2015,
2016,
2017,
2018,
2019,
2020,
2021, and
2023, we’ve got you covered. Purchasing Drive Shafts and Axles from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Drive Shafts and Axles that fit your vehicle.
Essential 2022 GMC Sierra 2500 HD Drive Shafts and Axles
Dorman – Axle Flange Gasket Kit (Part No.926-573)
from
$21.49
Ensure a leak-free repair when servicing axle bearings or parking brake shoes. This axle shaft flange seal is a direct replacement for the original gasket and should be replaced every time work is performed at the axle flange.
Product Features:
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Product Features:
- Ideal replacement – this axle shaft flange seal directly replaces the original gasket without having to visit the dealer
- Required for routine service – this gasket should be replaced every time work is performed at the axle flange
- Durable construction – this axle shaft flange gasket is made of tough, durable materials for leak-free performance
- Quality tested – this flange gasket has been designed and tested for a guaranteed fit
Felpro – Drive Axle Shaft Flange Gasket 8 Bolt Hole Gasket, 2.719 Inch Inside Diameter, 4.438 Inch Outside Diameter (Part No.55350)
from
$5.79
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Unsurpassed quality you can trust
- Validated for fit, form and function
- Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
Yukon Gear – Full-Floating Axle Seal For GM 14T (Part No.30018)
from
$13.99
Full-floating axle seal for GM 14T.Yukon Mighty seal.
Product Features:
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Product Features:
- Rear axle seal
- Fits GM 10.5″ 14 bolt truck
Yukon Gear – GM 9.25 IFS Side Seal, 1998 & Up (Part No.30161)
from
$24.99
GM 9.25 IFS side seal, 1998 & up.Yukon Mighty seal.
Product Features:
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Product Features:
- Stub axle seal
- Fits 1998 and up GM 9.25″ IFS
- 2.40″ O.D.
National – Drive Axle Shaft Seal (Part No.710926)
from
$73.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
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Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -40 Deg. F to 400 Deg. F / -40 Deg. C to 204 Deg. C
- Excellent high temperature capabilities
- Compatible with wide range of fluids
- Delivers quality and reliable performance for every type of repair
Yukon Gear – Inner Stub Axle Side Seal For GM 9.25" IFS (Part No.30146)
from
$17.99
Inner stub axle side seal for GM 9.25″ IFS.Yukon Mighty seal.
Product Features:
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Product Features:
- Inner stub axle seal
- Fits GM 9.25″ IFS
National – Multi-Purpose Seal (Part No.710497)
from
$17.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
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Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
- Resistance to EP lubricants
- Low swell in hydrocarbon fluids
- Delivers quality and reliable performance for every type of repair
FAG US – Shaft Seal (Part No.SS2678)
from
$20.49
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.
Product Features:
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Product Features:
- High-precision and High-quality components used in all KITs
- Coverage of classic and new high-tech solutions for the best system coverage
GM Genuine Parts – Axle Shaft Seal (Part No.291-336)
from
$59.99
GM Genuine Parts Axle Shaft Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help keep dirt and water out of your axle shaft assembly and seal in lubricant. They conform to the rotating surface to help provide leak-free operation. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Helps keep dirt and water out of your axle shaft assembly
- Conforms to the rotating surface to help provide leak-free operation
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Popular 2022 GMC Sierra 2500 HD Drive Shafts and Axles Categories
Most Popular Axle Shaft Seal for 2022 GMC Sierra 2500 HDs
Enhance your 2022 GMC Sierra 2500 HD with this popular Axle Shaft Seal we have in stock, for $59.99.
GM Genuine Parts – Axle Shaft Seal (Part No.291-336)
from
$59.99
GM Genuine Parts Axle Shaft Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help keep dirt and water out of your axle shaft assembly and seal in lubricant. They conform to the rotating surface to help provide leak-free operation. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
See More
Product Features:
- Helps keep dirt and water out of your axle shaft assembly
- Conforms to the rotating surface to help provide leak-free operation
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Best-Selling 2022 GMC Sierra 2500 HD Axle Flange Gasket
Upgrade your Sierra 2500 HD with our best-selling Axle Flange Gasket.
Dorman – Axle Flange Gasket Kit (Part No.926-573)
from
$21.49
Ensure a leak-free repair when servicing axle bearings or parking brake shoes. This axle shaft flange seal is a direct replacement for the original gasket and should be replaced every time work is performed at the axle flange.
Product Features:
See More
Product Features:
- Ideal replacement – this axle shaft flange seal directly replaces the original gasket without having to visit the dealer
- Required for routine service – this gasket should be replaced every time work is performed at the axle flange
- Durable construction – this axle shaft flange gasket is made of tough, durable materials for leak-free performance
- Quality tested – this flange gasket has been designed and tested for a guaranteed fit
FAQs for 2022 GMC Sierra 2500 HD Drive Shafts and Axles
What are the best-selling Drive Shafts and Axles for 2022 GMC Sierra 2500 HDs?
Out of 2 Drive Shafts and Axles that fit 2022 GMC Sierra 2500 HDs, the following parts are the top sellers:
- Axle Shaft Seal (11403343) – $59.99
- Axle Flange Gasket Kit (12351842) – $21.49
What’s the price range for 2022 GMC Sierra 2500 HD Drive Shafts and Axles?
The prices of Drive Shafts and Axles for the 2022 GMC Sierra 2500 HD range from $21.49 up to $59.99 for the most premium parts.
What is the average price of a Drive Shafts and Axle for a 2022 GMC Sierra 2500 HD?
The average price for Drive Shafts and Axles for the 2022 GMC Sierra 2500 HD is $40.74. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Drive Shafts and Axles for other GMC Sierra 2500 HD model years?
What are the cheapest Drive Shafts and Axles for my 2022 GMC Sierra 2500 HD?
The cheapest 2022 GMC Sierra 2500 HD Drive Shafts and Axles we carry are:
- Axle Flange Gasket Kit (12351842) – $21.49
- Axle Shaft Seal (11403343) – $59.99
Does Advance Auto Parts sell Drive Shafts and Axles for any other 2022 GMC models?
Yes. We stock Drive Shafts and Axles for 7 other popular 2022 GMC models. Some of the most popular are 2022 Sierra 3500 HD Drive Shafts and Axles, 2022 Terrain Drive Shafts and Axles, 2022 Acadia Drive Shafts and Axles, 2022 Savana 3500 Drive Shafts and Axles, and 2022 Savana 4500 Drive Shafts and Axles.
What types of Drive Shafts and Axles do you sell for my 2022 GMC Sierra 2500 HD?
As of 11/2/25, these are some of the most in-demand types of Drive Shafts and Axles for a 2022 GMC Sierra 2500 HD:
Can I get help with 2022 GMC Sierra 2500 HD Drive Shafts and Axle orders?
Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about GMC Drive Shafts and Axles and more.
What is your return policy for GMC Sierra 2500 HD Drive Shafts and Axles?
Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.