2021 Ram 2500 Drive Shafts and Axles

Keep Your 2021 Ram 2500 in Top Shape with Quality Drive Shafts and Axles

Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2021 Ram 2500 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Axle Shaft Universal Joints, Center Support Bearings, and Axle Shaft Seals. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Explore Related Parts

While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Differentials and Spindles. At Advance Auto Parts, we’re here to help you keep your 2021 Ram 2500 in peak condition, inside and out.

Essential 2021 Ram 2500 Drive Shafts and Axles

Yukon Gear – 9.25" Aam Front Solid Axle Inner Axle Seal, 2003 & Up Dodge Ram 2500/3500 (Part No.30236)

9.25" Aam Front Solid Axle Inner Axle Seal, 2003 & Up Dodge Ram 2500/3500

from

$44.99
9.25″ AAM front solid axle inner axle seal, 2003 & up Dodge Ram 2500/3500.Yukon Mighty seal.

Product Features:
  • Front inner axle seal
  • Fits Chrysler 9.25″ front
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National – Drive Axle Shaft Seal (Part No.710874)

Drive Axle Shaft Seal

from

$33.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: springless; multi-lip
  • Temperature range: -40 Deg. F to 400 Deg. F / -40 Deg. C to 204 Deg. C
  • Excellent high temperature capabilities
  • Compatible with wide range of fluids
  • Delivers quality and reliable performance for every type of repair
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Spicer – Universal Joint (Part No.5-1350X)

Universal Joint

from

$45.99
You expect a lot from your vehicle, and Spicer Life Series (SPL) universal joints deliver. SPL universal joints consistently outperform competitors, so you can hit the road or trail with confidence. Check out the difference that SPL universal joints can make in your vehicle, and make sure you are getting the longer life, increased bearing capacity and lower maintenance costs that Spicer Life Series (SPL) can provide.
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Spicer – Drive Axle Shaft Universal Joint (Part No.5-3212X)

Drive Axle Shaft Universal Joint

from

$76.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.
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Yukon Gear – UniversalJoint (Part No.42026)

UniversalJoint

from

$125.99
UniversalJoint

Spicer – Universal Joint, Greaseable 1410 Series (Part No.5-160X)

Universal Joint, Greaseable 1410 Series

from

$45.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.

Product Features:
  • OE engineering and field tested experience is why the Spicer brand is the most trusted in the industry.
  • Forged with high-quality steel, these u-joints are heat treated and case-hardened with precision to specific levels, ensuring optimal strength and durability.
  • The process of precision grinding the seal and bearing surfaces helps to improve the life of the seal and bearing.
  • Zerk allows for lubricating at regular intervals to help extend the life of the part.
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Spicer – Universal Joint, Greaseable 1350 Series (Part No.5-178X)

Universal Joint, Greaseable 1350 Series

from

$44.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.

Product Features:
  • OE engineering and field tested experience is why the Spicer brand is the most trusted in the industry.
  • Forged with high-quality steel, these u-joints are heat treated and case-hardened with precision to specific levels, ensuring optimal strength and durability.
  • The process of precision grinding the seal and bearing surfaces helps to improve the life of the seal and bearing.
  • Zerk allows for lubricating at regular intervals to help extend the life of the part.
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Driveworks – Universal Joint (Part No.DW-331BL)

Universal Joint

from

$15.99
Driveworks Universal Joints are designed to meet or exceed OE fit, form, and function. These universal joints are set to provide superior quality and easy installation. Driveworks Universal Joints are constructed from quality materials for extended durability. Driveworks Universal Joints are pre-lubricated with premium grease to provide a longer service life. The grease fittings are pre-installed to allow for easy maintenance (where applicable).

Product Features:
  • The cross is hot forged for the higher torque and horsepower
  • The bearing cups are made by cold forging, having higher strength and better rigidity
  • Bearing cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
  • Lubrication grooves are designed to ensure grease penetration to entire journal and needle bearings
  • Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
  • Snap rings are held to strict tolerances to ensure proper cup position and retention
  • Nitrile rubber seals to optimize grease retention and reduce contamination
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Spicer – Universal Joint (Part No.5-1350-1X)

Universal Joint

from

$49.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.
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Anchor – Center Support Bearing Motor Mount: Rear, 1 Piece (Part No.6139)

Center Support Bearing Motor Mount: Rear, 1 Piece

from

$143.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to FORD 17-21; RAM 19-21;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 2017-2021
  • Weight approx: 5 Lbs
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Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6110)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$79.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to DODGE 10-10; RAM 11-12;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 2010-2012
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.48 INCH / 63 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: HORSESHOE
  • ALUMINUM ALLOY
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Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6109)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$141.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to DODGE 06-10; RAM 11-11;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 2006-2011
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.00 INCH / 51 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: ROUND FRAME
  • WITH WINGS
  • WITHOUT STUDS
  • COLLAR FACES TRANSFER CASE
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Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6079)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$79.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to CHEV 92-05; DODGE 84-10; GMC 92-05; RAM 11-20;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1984-2020
  • Weight approx: 4 Lbs
  • BEARING ID / BORE: 1.3780 INCH / 35 MM
  • CENTERLINE: 2.28 INCH / 58 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: SQUARE FRAME
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Dorman – Center Support Bearing (Part No.934-030)

Center Support Bearing

from

$213.99
This drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles
  • Restores functionality – this bearing is made to fit and fully restore part functionality after the original bearing fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Most Popular Axle Shaft Universal Joints for 2021 Ram 2500s

Enhance your 2021 Ram 2500 with one of the 2 Axle Shaft Universal Joints we have in stock, starting at just $76.99.

Yukon Gear – UniversalJoint (Part No.42026)

UniversalJoint

from

$125.99
UniversalJoint

Spicer – Drive Axle Shaft Universal Joint (Part No.5-3212X)

Drive Axle Shaft Universal Joint

from

$76.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.
See More

Best-Selling 2021 Ram 2500 Center Support Bearing

Upgrade your 2500 with our best-selling Center Support Bearing.

Anchor – Center Support Bearing Motor Mount: Rear, 1 Piece (Part No.6139)

Center Support Bearing Motor Mount: Rear, 1 Piece

from

$143.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to FORD 17-21; RAM 19-21;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 2017-2021
  • Weight approx: 5 Lbs
See More

Top-Quality Axle Shaft Seals for 2021 Ram 2500s

Choose a high-quality OEM or aftermarket Axle Shaft Seal for Ram 2500s and enjoy top-notch performance from $44.99.

Yukon Gear – 9.25" Aam Front Solid Axle Inner Axle Seal, 2003 & Up Dodge Ram 2500/3500 (Part No.30236)

9.25" Aam Front Solid Axle Inner Axle Seal, 2003 & Up Dodge Ram 2500/3500

from

$44.99
9.25″ AAM front solid axle inner axle seal, 2003 & up Dodge Ram 2500/3500.Yukon Mighty seal.

Product Features:
  • Front inner axle seal
  • Fits Chrysler 9.25″ front
See More

FAQs for 2021 Ram 2500 Drive Shafts and Axles

What are the best-selling Drive Shafts and Axles for 2021 Ram 2500s?

Out of 4 Drive Shafts and Axles that fit 2021 Ram 2500s, the following parts are the top sellers:

What’s the price range for 2021 Ram 2500 Drive Shafts and Axles?

The prices of Drive Shafts and Axles for the 2021 Ram 2500 range from $44.99 up to $143.99 for the most premium parts.

What is the average price of a Drive Shafts and Axle for a 2021 Ram 2500?

The average price for Drive Shafts and Axles for the 2021 Ram 2500 is $97.99. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drive Shafts and Axles for other Ram 2500 model years?

Yes, we carry Drive Shafts and Axles for 12 model years of Ram 2500s between 2011 and 2024. The following model years are the most popular for Drive Shafts and Axle purchases: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Drive Shafts and Axles for my 2021 Ram 2500?

The cheapest 2021 Ram 2500 Drive Shafts and Axles we carry are:

Does Advance Auto Parts sell Drive Shafts and Axles for any other 2021 Ram models?

What types of Drive Shafts and Axles do you sell for my 2021 Ram 2500?

As of 11/2/25, these are some of the most in-demand types of Drive Shafts and Axles for a 2021 Ram 2500:

Can I get help with 2021 Ram 2500 Drive Shafts and Axle orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ram Drive Shafts and Axles and more.

What is your return policy for Ram 2500 Drive Shafts and Axles?

Advance Auto Parts keeps returns simple. For new Ram 2500 Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.