2021 Mercedes-Benz E350 Fluids

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Keep Your 2021 Mercedes-Benz E350 in Top Shape with Quality Fluids

Whether you’re repairing or upgrading your Fluid, using high-quality parts is key to keeping your 2021 Mercedes-Benz E350 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Brake Fluids, Transfer Case Fluids, and Electric Vehicle (EV) Reduction Gear Fluid. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Fluids from Trusted Brands

Looking for a reliable Fluid? We’ve got you covered with options from brands you know and trust like LIQUI MOLY, Valvoline, and Pentosin. For example, LIQUI MOLY Fluids start at just $16.99 with an average 4.9 star rating. Valvoline and Pentosin offer similar pricing and quality, backed by strong customer feedback. With over 1,672 reviews and a solid 5 star average, you can shop with confidence knowing other Mercedes-Benz E350 owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2021 Mercedes-Benz E350 Fluid at Advance Auto Parts is around $26.10, with a range that starts at $7.99 and goes up to $72.99. With 14 options in stock from 4 trusted brands, finding the right fit is easy. Popular picks like Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart, Pentosin Super Dot 4 5L, and Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil, Smooth Engine Running, 1 Liter start at just $17.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Fluid, don’t forget to check out other key components like Coolant/Antifreeze and Transmission Fluids. At Advance Auto Parts, we’re here to help you keep your 2021 Mercedes-Benz E350 in peak condition, inside and out.

Essential 2021 Mercedes-Benz E350 Fluids

Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.889785)

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

from

$18.99
We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:
  • FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations.
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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Valvoline – Restore & Protect Automatic Transmission Fluid 1 Ga (Part No.913033)

Restore & Protect Automatic Transmission Fluid 1 Ga

from

$37.99
Most transmissions are automatic. Now, so is choosing an ATF. Introducing Valvoline Restore & Protect Automatic Transmission Fluid, a premium full synthetic ATF suitable for use in 95% of vehicles. Leveraging innovation from our groundbreaking Valvoline Restore & Protect Motor Oil, the same trusted technology is now available in transmission care. Restore & Protect ATF provides up to 97% deposit removal with Active Dissolve Technology, so there’s no need to add a transmission cleaner. Valvoline’s full synthetic formula outperforms conventional ATF with outstanding protection against friction, thermal stability and transmission breakdown. The high performance multi-vehicle protection revitalizes, defends and maximizes automatic transmission life. Whether it’s a Ford, GM, Toyota, Honda, Hyundai, Subaru, BMW, Mercedes, VW and more, you get exceptional performance in any driving condition. For unsurpassed deposit removal and smoother shifting, trust Valvoline Restore & Protect Full Synthetic Automatic Transmission Fluid, from the number 1 ATF brand.

Product Features:
  • Removes up to 97% of damaging deposits with Active Dissolve Technology, so you can skip the transmission cleaner
  • The number 1 ATF brand brings the same innovation from Valvoline Restore & Protect Motor Oil to its groundbreaking automatic transmission fluid technology
  • Valvoline Restore & Protect Automatic Transmission Fluid is suitable for use in more than 95% of ATF vehicles in operation with US registered light duty applications
  • Premium full synthetic formula with advanced additive chemistry fights harmful friction and thermal breakdown to help prevent costly transmission repairs
  • Proven to maximize transmission life, the high performance protection revitalizes, defends, minimizes deposits and ensures smooth shifting
  • Recommended For Use In Applications Requiring Dexron 6, Dexron 3, Dexron 2, Mercon Lv, And Jaso M315-2013 1A-Lv
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Valvoline – Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon (Part No.882505)

Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon

from

$59.99
Valvoline SAE 75W-90 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our detergent package-based formulation contains Full Synthetic base stocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance. Protect your gears with Valvoline, the No. 1 gear oil brand.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION , ranging from -30 Deg F to 300 Deg F
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTIONá, ranging from -30 Deg F to 300 Deg F
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALS where APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALSáwhere APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS THE PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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Castrol – Edge 5W-30 Full Synthetic Motor Oil, Maximizes Motor Performance, 1 Quart (Part No.15D452)

Edge 5W-30 Full Synthetic Motor Oil, Maximizes Motor Performance, 1 Quart

from

$12.49
EDGE 5W-30 Full Synthetic Motor Oil is expertly designed to meet the demands of highly tuned four-cylinder and advanced technology engines that operate at elevated temperatures. With its full synthetic composition, this oil delivers exceptional lubrication to critical engine components, ensuring smooth operation from the valve train to the bearings. Classified as standard with an SAE oil weight of 5W-30, it provides the strength and stability needed to maximize engine performance, even under high-temperature conditions. Its advanced formulation helps maintain optimal lubrication, reducing wear and enhancing the longevity of your engine. Packaged in a convenient 1-quart size, it’s perfect for quick top-offs or completing a full oil change, offering both reliability and ease of use.

Product Features:


    Product Features:
    • Expertly formulated for highly tuned four-cylinder and latest technology engines that operate at higher temperatures.
    • Full synthetic composition ensures exceptional lubrication for all engine components, from the valve train to the bearings.
    • Classified as standard with an SAE oil weight of 5W-30, providing the strength needed for maximum engine performance.
    • Helps maximize engine performance by maintaining optimal lubrication under high-temperature conditions.
    • Comes in a convenient 1 QT size, perfect for top-offs or completing oil changes.
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LIQUI MOLY – Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil, Smooth Engine Running, 1 Liter (Part No.2038)

Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil, Smooth Engine Running, 1 Liter

from

$17.99
Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil is expertly crafted for diesel engines, particularly those equipped with diesel particulate filters (DPF). This low SAPS formula ensures smooth engine running and is ideal for use with turbochargers and catalytic converters, delivering excellent wear protection and extending engine service life. Its advanced composition guarantees fast oil penetration, optimizing performance and reliability even under demanding conditions. Designed for extended oil change intervals as per manufacturer recommendations, this 5W-30 oil supports long-term efficiency while maintaining superior protection. Made in Germany, it reflects precision engineering and quality, making it a dependable choice for diesel engine care.

Product Features:


    Product Features:
    • smooth engine running
    • ideal with turbochargers and catalytic converters
    • long engine service life
    • Excellent wear protection
    • Ensures fast oil penetration of the engine
    • Made in Germany
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Idemitsu – Type TLS Automatic Transmission Fluid, 1 Quart (Part No.30040093-75000C)

Type TLS Automatic Transmission Fluid, 1 Quart

from

$14.49
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of ATF T-IV. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF T-IV is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. Idemitsu is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. Idemitsu application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Provides superior cleanliness, maintaining the transmission free of sludge and varnish deposits
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
  • Advanced anti-wear technology provides maximum protection to gears and bearings
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
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LIQUI MOLY – Special Tec LL 5W-30 Full Synthetic Motor Oil, Reduces Frictional Loss, 1 Liter (Part No.2248)

Special Tec LL 5W-30 Full Synthetic Motor Oil, Reduces Frictional Loss, 1 Liter

from

$16.99
All-year oil for gasoline and diesel engines. Modern multi-purpose low-friction motor oil developed according to the latest technology. Unconventional base oils based on HC synthetic technology were combined with the most modern additive technology. The low-viscosity and high sheer stability of the motor oil guarantees optimal cleanliness, reduces frictional loss in the engine and provides outstanding protection against wear. The results are savings in fuel and an extended service life for the engine. Tested for turbochargers and catalytic converters.

Product Features:
  • High-tech low-viscosity engine oil
  • Advance wear protection formula
  • Fastest cold start oiling during start up
  • Provides ideal oil pressure under all operating conditions
  • Keep oil consumption low
  • Made in germany
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LIQUI MOLY – Longtime High Tech 5W-30 Full Synthetic Engine Oil, Excellent Wear Protection, 5 Liter (Part No.2039)

Longtime High Tech 5W-30 Full Synthetic Engine Oil, Excellent Wear Protection, 5 Liter

from

$49.99
Longtime High Tech 5W-30 Full Synthetic Engine Oil is expertly crafted for diesel engines, offering exceptional performance and protection. Designed with Low SAPS technology, it is ideal for vehicles equipped with diesel particulate filters (DPF), ensuring compatibility with modern emission systems. This premium 5W-30 oil promotes smooth engine operation, making it perfect for engines with turbochargers and catalytic converters. Its advanced formula delivers excellent wear protection, prolonging engine service life while supporting extended oil change intervals as recommended by manufacturers. Engineered for fast oil penetration, it ensures optimal lubrication from the moment you start your vehicle. Made in Germany, this full synthetic oil is a reliable choice for maintaining peak engine performance and efficiency.

Product Features:


    Product Features:
    • Smooth engine running
    • Ideal with turbochargers and catalytic converters
    • Long engine service life
    • Excellent wear protection
    • Ensures fast oil penetration of the engine
    • Made in Germany
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Valvoline – Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.898795)

Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant ¿ from the brand trusted for over 150 years.

Product Features:
  • Full synthetic hybrid ATF with Copper Care Technology, from the No. 1 ATF brand
  • Enhanced protection against corrosion that can result in hybrid transmission failure
  • Protects electrical systems maximizing transmission efficiency
  • Increased heat transfer capabilities to protect against higher temperatures produced by hybrids
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LIQUI MOLY – Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter (Part No.2004)

Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter

from

$16.99
High-tech low-friction motor oil based on synthetic technology. Ensures excellent engine cleanliness and exceeds even the strictest test requirements of well-known vehicle manufacturers. Reduces the build-up of troublesome deposits in direct-injection gasoline and diesel engines (FSI, TDI, common rail, etc.) and keeps oil consumption low. Assures reliable operation and maximizes the operating life of the diesel particulate filter (DPF). Specifically for vehicles with extremely long oil change intervals (WIV, etc.). Outstanding protection against wear, reduces oil and fuel consumption and ensures fast oil penetration of the engine.

Product Features:
  • Outstanding protection against wear
  • Reduces oil and fuel consumption
  • Ensure fast oil penetration of the engine
  • High tech low friction based on synthetic technology
  • Made in germany
  • Full Synthetic Oil Composition
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LIQUI MOLY – Special Tec LL 5W-30 Full Synthetic Engine Oil, High Lubrication Reliability, 5 Liter (Part No.2249)

Special Tec LL 5W-30 Full Synthetic Engine Oil, High Lubrication Reliability, 5 Liter

from

$46.99
Special Tec LL 5W-30 Full Synthetic Engine Oil is engineered to deliver exceptional performance and long-lasting engine protection for both gasoline and diesel vehicles without particulate filters. This premium, fully synthetic oil is designed to meet and exceed the stringent requirements of major manufacturers, making it ideal for modern engines equipped with turbochargers and catalytic converters. With its high lubrication reliability, outstanding engine cleanliness, and optimum stability to aging, this oil ensures your engine runs smoothly under all conditions. Its advanced formulation helps keep oil consumption low while supporting extended oil change intervals as recommended by your vehicle’s manufacturer. Made in Germany, this SAE 5W-30 oil offers superior all-season performance, ensuring your engine stays protected and efficient year-round.

Product Features:


    Product Features:
    • ideal with turbochargers and catalytic converters
    • high lubrication reliability
    • outstanding engine cleanliness
    • optimum stability to aging
    • Keep oil consumption low
    • Made in germany
See More

Valvoline – Restore & Protect Automatic Transmission Fluid 1 Qt (Part No.913031)

Restore & Protect Automatic Transmission Fluid 1 Qt

from

$14.99
Most transmissions are automatic. Now, so is choosing an ATF. Introducing Valvoline Restore & Protect Automatic Transmission Fluid, a premium full synthetic ATF suitable for use in 95% of vehicles. Leveraging innovation from our groundbreaking Valvoline Restore & Protect Motor Oil, the same trusted technology is now available in transmission care. Restore & Protect ATF provides up to 97% deposit removal with Active Dissolve Technology, so there’s no need to add a transmission cleaner. Valvoline’s full synthetic formula outperforms conventional ATF with outstanding protection against friction, thermal stability and transmission breakdown. The high performance multi-vehicle protection revitalizes, defends and maximizes automatic transmission life. Whether it’s a Ford, GM, Toyota, Honda, Hyundai, Subaru, BMW, Mercedes, VW and more, you get exceptional performance in any driving condition. For unsurpassed deposit removal and smoother shifting, trust Valvoline Restore & Protect Full Synthetic Automatic Transmission Fluid, from the number 1 ATF brand.

Product Features:
  • Removes up to 97% of damaging deposits with Active Dissolve Technology, so you can skip the transmission cleaner
  • The number 1 ATF brand brings the same innovation from Valvoline Restore & Protect Motor Oil to its groundbreaking automatic transmission fluid technology
  • Valvoline Restore & Protect Automatic Transmission Fluid is suitable for use in more than 95% of ATF vehicles in operation with US registered light duty applications
  • Premium full synthetic formula with advanced additive chemistry fights harmful friction and thermal breakdown to help prevent costly transmission repairs
  • Proven to maximize transmission life, the high performance protection revitalizes, defends, minimizes deposits and ensures smooth shifting
  • Recommended For Use In Applications Requiring Dexron 6, Dexron 3, Dexron 2, Mercon Lv, And Jaso M315-2013 1A-Lv
See More

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$9.99
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA

Product Features:
  • FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
  • HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
  • IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
  • ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
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Pentosin – Pentosin Super Dot 4 5L (Part No.1204204)

Pentosin Super Dot 4 5L

from

$72.99
Pentosin Super DOT 4 is a brake fluid of superior quality for universal use in modern brake systems and ideal for vehicles with ABS systems. Pentosin Super DOT 4 offers safety against vapor lock; it has excellent resistance to absorbing and retaining water and provides superior corrosion resistance.

Product Features:
  • Safety against vapor lock
  • Provides superior corrosion resistance
  • Long-term resistance to absorbing and retaining water.
See More

Prestone – MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 32 fl. oz. (Part No.AS810)

MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 32 fl. oz.

from

$15.49
Prestone MAX DOT 4 Motor Vehicle Brake Fluid is our highest grade formula, maximizing performance vs. DOT standard. Prestone MAX is our best brake fluid at protecting against overheating and brake fade. With 75,000 mile fluid life, our longest life fluid has 1.5X more miles between replacement than regular Prestone DOT 3. Prestone MAX has superior performance in severe braking conditions when compared to regular Prestone DOT 4, which means even more piece of mind about the braking system. This synthetic fluid starts with our highest dry boiling point giving our best protection against performance decline due to water absorption. Prestone MAX DOT 4 is safe to use in all DOT 4 braking systems, ABS, disc or drum, and can mix with any DOT 4 fluid. Mixing Prestone MAX with other fluids will lower the performance rating for miles and boil points, for best results replace completely with Prestone MAX DOT 4. It is recommended to only use the DOT fluid specified for your car. Using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 75,000 Mile Fluid Life
  • Prevent Overheating and Brake Fade with Our Highest Grade Formula. Prevents corrosion of all metals within the braking system.
  • Superior Protection in Extreme Braking Conditions
  • Synthetic, Long Life Formula – 1.5X Longer than regular Prestone DOT 4
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Prestone – DOT 4 Brake Fluid: Synthetic, High Grade, Prevents Overheating & Brake Fade, 50k miles, 32 oz. (Part No.AS801Y)

DOT 4 Brake Fluid: Synthetic, High Grade, Prevents Overheating & Brake Fade, 50k miles, 32 oz.

from

$13.49
Prestone DOT 4 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 4. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system.  This formula is safe to use in all DOT 4 braking systems (ABS, disc or drum) and can mix with any DOT 4 fluid.  It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 50,000 Mile Fluid Life
  • Prevent Overheating and Brake Fade with High Grade Formula
  • Protects against performance decline due to water absorption. Prevents corrosion of all metals within the braking system.
  • Synthetic, Extended Fluid Life Formula
See More

Prestone – MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 12 fl. oz. (Part No.AS815)

MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 12 fl. oz.

from

$7.99
Prestone® DOT 4 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 4. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system. This formula is safe to use in all DOT 4 braking systems (ABS, disc or drum) and can mix with any DOT 4 fluid. It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 50,000 Mile Fluid Life
  • Prevent Overheating & Brake Fade with High Grade Formula*
  • Protects against performance decline due to water absorption. Prevents corrosion of all metals within the braking system
  • Synthetic, Extended Fluid Life Formula
See More

Prestone – DOT 4 Brake Fluid: Synthetic, High Grade, 50,000 Mile, 12 fl. oz. (Part No.AS800Y)

DOT 4 Brake Fluid: Synthetic, High Grade, 50,000 Mile, 12 fl. oz.

from

$7.99
Prestone DOT 4 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 4. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system.  This formula is safe to use in all DOT 4 braking systems (ABS, disc or drum) and can mix with any DOT 4 fluid.  It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 50,000 Mile Fluid Life
  • Prevent Overheating and Brake Fade with High Grade Formula
  • Protects against performance decline due to water absorption. Prevents corrosion of all metals within the braking system.
  • Synthetic, Extended Fluid Life Formula
See More

Most Popular Brake Fluids for 2021 Mercedes-Benz E350s

Enhance your 2021 Mercedes-Benz E350 with one of the 5 Brake Fluids we have in stock, starting at just $7.99.

Pentosin – Pentosin Super Dot 4 5L (Part No.1204204)

Pentosin Super Dot 4 5L

from

$72.99
Pentosin Super DOT 4 is a brake fluid of superior quality for universal use in modern brake systems and ideal for vehicles with ABS systems. Pentosin Super DOT 4 offers safety against vapor lock; it has excellent resistance to absorbing and retaining water and provides superior corrosion resistance.

Product Features:
  • Safety against vapor lock
  • Provides superior corrosion resistance
  • Long-term resistance to absorbing and retaining water.
See More

Prestone – MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 32 fl. oz. (Part No.AS810)

MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 32 fl. oz.

from

$15.49
Prestone MAX DOT 4 Motor Vehicle Brake Fluid is our highest grade formula, maximizing performance vs. DOT standard. Prestone MAX is our best brake fluid at protecting against overheating and brake fade. With 75,000 mile fluid life, our longest life fluid has 1.5X more miles between replacement than regular Prestone DOT 3. Prestone MAX has superior performance in severe braking conditions when compared to regular Prestone DOT 4, which means even more piece of mind about the braking system. This synthetic fluid starts with our highest dry boiling point giving our best protection against performance decline due to water absorption. Prestone MAX DOT 4 is safe to use in all DOT 4 braking systems, ABS, disc or drum, and can mix with any DOT 4 fluid. Mixing Prestone MAX with other fluids will lower the performance rating for miles and boil points, for best results replace completely with Prestone MAX DOT 4. It is recommended to only use the DOT fluid specified for your car. Using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 75,000 Mile Fluid Life
  • Prevent Overheating and Brake Fade with Our Highest Grade Formula. Prevents corrosion of all metals within the braking system.
  • Superior Protection in Extreme Braking Conditions
  • Synthetic, Long Life Formula – 1.5X Longer than regular Prestone DOT 4
See More

Prestone – DOT 4 Brake Fluid: Synthetic, High Grade, Prevents Overheating & Brake Fade, 50k miles, 32 oz. (Part No.AS801Y)

DOT 4 Brake Fluid: Synthetic, High Grade, Prevents Overheating & Brake Fade, 50k miles, 32 oz.

from

$13.49
Prestone DOT 4 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 4. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system.  This formula is safe to use in all DOT 4 braking systems (ABS, disc or drum) and can mix with any DOT 4 fluid.  It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 50,000 Mile Fluid Life
  • Prevent Overheating and Brake Fade with High Grade Formula
  • Protects against performance decline due to water absorption. Prevents corrosion of all metals within the braking system.
  • Synthetic, Extended Fluid Life Formula
See More

Prestone – DOT 4 Brake Fluid: Synthetic, High Grade, 50,000 Mile, 12 fl. oz. (Part No.AS800Y)

DOT 4 Brake Fluid: Synthetic, High Grade, 50,000 Mile, 12 fl. oz.

from

$7.99
Prestone DOT 4 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 4. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system.  This formula is safe to use in all DOT 4 braking systems (ABS, disc or drum) and can mix with any DOT 4 fluid.  It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 50,000 Mile Fluid Life
  • Prevent Overheating and Brake Fade with High Grade Formula
  • Protects against performance decline due to water absorption. Prevents corrosion of all metals within the braking system.
  • Synthetic, Extended Fluid Life Formula
See More

Prestone – MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 12 fl. oz. (Part No.AS815)

MAX DOT 4 Brake Fluid, Synthetic, Highest Grade, 75,000 Mile, 12 fl. oz.

from

$7.99
Prestone® DOT 4 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 4. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system. This formula is safe to use in all DOT 4 braking systems (ABS, disc or drum) and can mix with any DOT 4 fluid. It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.

Product Features:
  • 50,000 Mile Fluid Life
  • Prevent Overheating & Brake Fade with High Grade Formula*
  • Protects against performance decline due to water absorption. Prevents corrosion of all metals within the braking system
  • Synthetic, Extended Fluid Life Formula
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Best-Selling 2021 Mercedes-Benz E350 Transfer Case Fluids

Upgrade your E350 with one of our 7 best-selling Transfer Case Fluids, earning an average 5 stars rating across 832 reviews.

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$9.99
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA

Product Features:
  • FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
  • HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
  • IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
  • ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
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Valvoline – Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon (Part No.882505)

Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon

from

$59.99
Valvoline SAE 75W-90 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our detergent package-based formulation contains Full Synthetic base stocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance. Protect your gears with Valvoline, the No. 1 gear oil brand.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION , ranging from -30 Deg F to 300 Deg F
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTIONá, ranging from -30 Deg F to 300 Deg F
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALS where APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALSáwhere APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS THE PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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LIQUI MOLY – Longtime High Tech 5W-30 Full Synthetic Engine Oil, Excellent Wear Protection, 5 Liter (Part No.2039)

Longtime High Tech 5W-30 Full Synthetic Engine Oil, Excellent Wear Protection, 5 Liter

from

$49.99
Longtime High Tech 5W-30 Full Synthetic Engine Oil is expertly crafted for diesel engines, offering exceptional performance and protection. Designed with Low SAPS technology, it is ideal for vehicles equipped with diesel particulate filters (DPF), ensuring compatibility with modern emission systems. This premium 5W-30 oil promotes smooth engine operation, making it perfect for engines with turbochargers and catalytic converters. Its advanced formula delivers excellent wear protection, prolonging engine service life while supporting extended oil change intervals as recommended by manufacturers. Engineered for fast oil penetration, it ensures optimal lubrication from the moment you start your vehicle. Made in Germany, this full synthetic oil is a reliable choice for maintaining peak engine performance and efficiency.

Product Features:


Product Features:
  • Smooth engine running
  • Ideal with turbochargers and catalytic converters
  • Long engine service life
  • Excellent wear protection
  • Ensures fast oil penetration of the engine
  • Made in Germany
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LIQUI MOLY – Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter (Part No.2004)

Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter

from

$16.99
High-tech low-friction motor oil based on synthetic technology. Ensures excellent engine cleanliness and exceeds even the strictest test requirements of well-known vehicle manufacturers. Reduces the build-up of troublesome deposits in direct-injection gasoline and diesel engines (FSI, TDI, common rail, etc.) and keeps oil consumption low. Assures reliable operation and maximizes the operating life of the diesel particulate filter (DPF). Specifically for vehicles with extremely long oil change intervals (WIV, etc.). Outstanding protection against wear, reduces oil and fuel consumption and ensures fast oil penetration of the engine.

Product Features:
  • Outstanding protection against wear
  • Reduces oil and fuel consumption
  • Ensure fast oil penetration of the engine
  • High tech low friction based on synthetic technology
  • Made in germany
  • Full Synthetic Oil Composition
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LIQUI MOLY – Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil, Smooth Engine Running, 1 Liter (Part No.2038)

Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil, Smooth Engine Running, 1 Liter

from

$17.99
Longtime High Tech 5W-30 Full Synthetic Diesel Engine Oil is expertly crafted for diesel engines, particularly those equipped with diesel particulate filters (DPF). This low SAPS formula ensures smooth engine running and is ideal for use with turbochargers and catalytic converters, delivering excellent wear protection and extending engine service life. Its advanced composition guarantees fast oil penetration, optimizing performance and reliability even under demanding conditions. Designed for extended oil change intervals as per manufacturer recommendations, this 5W-30 oil supports long-term efficiency while maintaining superior protection. Made in Germany, it reflects precision engineering and quality, making it a dependable choice for diesel engine care.

Product Features:


Product Features:
  • smooth engine running
  • ideal with turbochargers and catalytic converters
  • long engine service life
  • Excellent wear protection
  • Ensures fast oil penetration of the engine
  • Made in Germany
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Valvoline – Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.898795)

Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant ¿ from the brand trusted for over 150 years.

Product Features:
  • Full synthetic hybrid ATF with Copper Care Technology, from the No. 1 ATF brand
  • Enhanced protection against corrosion that can result in hybrid transmission failure
  • Protects electrical systems maximizing transmission efficiency
  • Increased heat transfer capabilities to protect against higher temperatures produced by hybrids
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Valvoline – Restore & Protect Automatic Transmission Fluid 1 Qt (Part No.913031)

Restore & Protect Automatic Transmission Fluid 1 Qt

from

$14.99
Most transmissions are automatic. Now, so is choosing an ATF. Introducing Valvoline Restore & Protect Automatic Transmission Fluid, a premium full synthetic ATF suitable for use in 95% of vehicles. Leveraging innovation from our groundbreaking Valvoline Restore & Protect Motor Oil, the same trusted technology is now available in transmission care. Restore & Protect ATF provides up to 97% deposit removal with Active Dissolve Technology, so there’s no need to add a transmission cleaner. Valvoline’s full synthetic formula outperforms conventional ATF with outstanding protection against friction, thermal stability and transmission breakdown. The high performance multi-vehicle protection revitalizes, defends and maximizes automatic transmission life. Whether it’s a Ford, GM, Toyota, Honda, Hyundai, Subaru, BMW, Mercedes, VW and more, you get exceptional performance in any driving condition. For unsurpassed deposit removal and smoother shifting, trust Valvoline Restore & Protect Full Synthetic Automatic Transmission Fluid, from the number 1 ATF brand.

Product Features:
  • Removes up to 97% of damaging deposits with Active Dissolve Technology, so you can skip the transmission cleaner
  • The number 1 ATF brand brings the same innovation from Valvoline Restore & Protect Motor Oil to its groundbreaking automatic transmission fluid technology
  • Valvoline Restore & Protect Automatic Transmission Fluid is suitable for use in more than 95% of ATF vehicles in operation with US registered light duty applications
  • Premium full synthetic formula with advanced additive chemistry fights harmful friction and thermal breakdown to help prevent costly transmission repairs
  • Proven to maximize transmission life, the high performance protection revitalizes, defends, minimizes deposits and ensures smooth shifting
  • Recommended For Use In Applications Requiring Dexron 6, Dexron 3, Dexron 2, Mercon Lv, And Jaso M315-2013 1A-Lv
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Top-Quality Electric Vehicle (EV) Reduction Gear Fluid for 2021 Mercedes-Benz E350s

Choose a high-quality OEM or aftermarket Electric Vehicle (EV) Reduction Gear Fluid for Mercedes-Benz E350s and enjoy top-notch performance from $37.99.

Valvoline – Restore & Protect Automatic Transmission Fluid 1 Ga (Part No.913033)

Restore & Protect Automatic Transmission Fluid 1 Ga

from

$37.99
Most transmissions are automatic. Now, so is choosing an ATF. Introducing Valvoline Restore & Protect Automatic Transmission Fluid, a premium full synthetic ATF suitable for use in 95% of vehicles. Leveraging innovation from our groundbreaking Valvoline Restore & Protect Motor Oil, the same trusted technology is now available in transmission care. Restore & Protect ATF provides up to 97% deposit removal with Active Dissolve Technology, so there’s no need to add a transmission cleaner. Valvoline’s full synthetic formula outperforms conventional ATF with outstanding protection against friction, thermal stability and transmission breakdown. The high performance multi-vehicle protection revitalizes, defends and maximizes automatic transmission life. Whether it’s a Ford, GM, Toyota, Honda, Hyundai, Subaru, BMW, Mercedes, VW and more, you get exceptional performance in any driving condition. For unsurpassed deposit removal and smoother shifting, trust Valvoline Restore & Protect Full Synthetic Automatic Transmission Fluid, from the number 1 ATF brand.

Product Features:
  • Removes up to 97% of damaging deposits with Active Dissolve Technology, so you can skip the transmission cleaner
  • The number 1 ATF brand brings the same innovation from Valvoline Restore & Protect Motor Oil to its groundbreaking automatic transmission fluid technology
  • Valvoline Restore & Protect Automatic Transmission Fluid is suitable for use in more than 95% of ATF vehicles in operation with US registered light duty applications
  • Premium full synthetic formula with advanced additive chemistry fights harmful friction and thermal breakdown to help prevent costly transmission repairs
  • Proven to maximize transmission life, the high performance protection revitalizes, defends, minimizes deposits and ensures smooth shifting
  • Recommended For Use In Applications Requiring Dexron 6, Dexron 3, Dexron 2, Mercon Lv, And Jaso M315-2013 1A-Lv
See More

Our Top Pick for a 2021 Mercedes-Benz E350 AWD Fluid

Invest in a durable AWD Fluid for your 2021 Mercedes-Benz, knowing you’re getting trusted brands and expert craftsmanship.

Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.889785)

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

from

$18.99
We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:
  • FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations.
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
See More

Top-Rated Fluid Brands For Your 2021 Mercedes-Benz E350

When it comes to finding the perfect Fluid for your 2021 Mercedes-Benz E350, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 4 trusted brands. We carry the most popular Fluid brands including LIQUI MOLY, Valvoline, and Pentosin, and more, all known for their exceptional customer ratings (average brand rating of 4.9 stars) and competitive prices, as low as $9.99. Purchasing a Fluid from us here at Advance Auto Parts is a smart move for both you and your 2021 Mercedes-Benz E350, providing peace of mind with parts that meet or exceed OEM standards.

Popular LIQUI MOLY 2021 Mercedes-Benz E350 Fluids

If you’re looking for a top-quality Fluid for your 2021 Mercedes-Benz E350, Advance Auto Parts has exactly what you need with our selection of LIQUI MOLY Fluids. We have 2 LIQUI MOLY Fluids in stock for this fitment, all known for their durability and precision fit. With prices starting at just $16.99 and an average cost of $33.49, you’ll find the perfect Fluid for your needs and budget. LIQUI MOLY Fluids for the 2021 Mercedes-Benz E350 come highly rated, with over 22 customer reviews and an impressive average rating of 4.9 stars. Choosing a LIQUI MOLY Fluid from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Longtime High Tech 5W-30 Full Synthetic Engine Oil, Excellent Wear Protection, 5 Liter
from $49.99
(21)
Longtime High Tech 5W-30 Full Synthetic Engine Oil, Excellent Wear Protection, 5 Liter
“A must for the longevity of your mini and a great oil all around”
Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter
from $16.99
(1)
Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter
“I use this oil in every oil change in my VW CC with the 2.0 tsi engine . Better yet if you have a engine with a turbo . This oil is great , with l”

Top-Quality Valvoline 2021 Mercedes-Benz E350 Fluids

For those in search of a high-quality Fluid for their 2021 Mercedes-Benz E350, Advance Auto Parts offers a great selection of Valvoline Fluids. With 2 Valvoline Fluids in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Fluids start at just $9.99, with an average price of $34.99, giving you a range of options to suit your budget. Backed by over 810 customer ratings and an average rating of 4.8 stars, Valvoline Fluids provide both reliability and excellent performance. Choosing a Valvoline Fluid from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.

FAQs for 2021 Mercedes-Benz E350 Fluids

What are the best-selling Fluids for 2021 Mercedes-Benz E350s?

Out of 14 Fluids that fit 2021 Mercedes-Benz E350s, the following parts are the top sellers:

What’s the price range for 2021 Mercedes-Benz E350 Fluids?

The prices of Fluids for the 2021 Mercedes-Benz E350 range from $7.99 up to $72.99 for the most premium parts.

What is the average price of a Fluid for a 2021 Mercedes-Benz E350?

The average price for Fluids for the 2021 Mercedes-Benz E350 is $26.10. Keep in mind the variety of part types within our Fluid category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Fluids for other Mercedes-Benz E350 model years?

Yes, we carry Fluids for 16 model years of Mercedes-Benz E350s between 2006 and 2026. The following model years are the most popular for Fluid purchases: 2023, 2022, 2020, 2016, 2015, 2014, 2013, 2012, and 2011.

Does Advance Auto Parts sell Fluids for any other 2021 Mercedes-Benz models?

Yes. We stock Fluids for 18 other popular 2021 Mercedes-Benz models. Some of the most popular are 2021 Sprinter 2500 Fluids, 2021 Sprinter 3500 Fluids, 2021 C300 Fluids, 2021 Metris Fluids, and 2021 S500 Fluids.

What are the top-rated Fluids that fit the 2021 Mercedes-Benz E350?

Based on 1,672 reviews by customers, our 2021 Mercedes-Benz E350 Fluids have an average customer rating of 5 stars. These are the highest-rated categories of Fluids for the 2021 Mercedes-Benz E350 and their top-rated products:

What types of Fluids do you sell for my 2021 Mercedes-Benz E350?

As of 3/1/26, these are some of the most in-demand types of Fluids for a 2021 Mercedes-Benz E350:

Can I get help with 2021 Mercedes-Benz E350 Fluid orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Fluids and more.

What is your return policy for Mercedes-Benz E350 Fluids?

Advance Auto Parts keeps returns simple. For new Mercedes-Benz E350 Fluids and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.