2021 Lexus RX450h Drive Shafts and Axles

Keep Your 2021 Lexus RX450h in Top Shape with Quality Drive Shafts and Axles

Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2021 Lexus RX450h looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Drive and Prop Shaft Assemblies and Drive Shaft and Axles. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2021 Lexus RX450h Drive Shafts and Axle at Advance Auto Parts is around $485.99, with a range that starts at $119.99 and goes up to $851.99. With 2 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like New CV Axle Assembly and Drive Shaft: Not Greasable, Direct Replacement start at just $119.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Differentials and Spindles. At Advance Auto Parts, we’re here to help you keep your 2021 Lexus RX450h in peak condition, inside and out.

Essential 2021 Lexus RX450h Drive Shafts and Axles

Cardone – Drive Shaft: Not Greasable, Direct Replacement (Part No.65-5042)

Drive Shaft: Not Greasable, Direct Replacement

from

$851.99
CARDONE Remanufactured Prop Shafts are engineered using the most stringent quality processes to deliver smooth, consistent performance in any driving condition. Original designs are scrutinized for potential improvement, and where applicable, design upgrades are implemented to produce a more durable part than the original. All critical components are tested to ensure proper function. Additionally, all CARDONE Prop Shafts are 100 percent dynamically balanced, resulting in vibration-free performance at all speeds.

Product Features:
  • Built to match O.E. form, fit and function.
  • 100 percent NEW universal joints are installed to ensure proper fit and optimal performance.
  • All slip yokes are lubricated to prevent premature wear.
  • Units are 100 percent dynamically balanced at 3200 RPMs for vibration-free operation and increased joint life.
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Cardone – Drive Shaft: Not Greasable, Direct Replacement (Part No.65-5036)

Drive Shaft: Not Greasable, Direct Replacement

from

$1307.99
CARDONE Remanufactured Prop Shafts are engineered using the most stringent quality processes to deliver smooth, consistent performance in any driving condition. Original designs are scrutinized for potential improvement, and where applicable, design upgrades are implemented to produce a more durable part than the original. All critical components are tested to ensure proper function. Additionally, all CARDONE Prop Shafts are 100 percent dynamically balanced, resulting in vibration-free performance at all speeds.

Product Features:
  • Built to match O.E. form, fit and function.
  • 100 percent NEW universal joints are installed to ensure proper fit and optimal performance.
  • All slip yokes are lubricated to prevent premature wear.
  • Units are 100 percent dynamically balanced at 3200 RPMs for vibration-free operation and increased joint life.
See More

Carquest Premium – New CV Axle Assembly (Part No.NCV902651)

New CV Axle Assembly

from

$119.99
Manufactured to be an OE replacement, CV axles use 100% new materials and are engineered for ease of installation and long service.

Product Features:
  • All New Materials
  • Engineered for OE Fitment
  • -40 Degree Rated CV Boots
  • Moly-Blend Grease in inner and outer joints
  • New nut and mounting hardware included if required
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Most Popular Drive and Prop Shaft Assembly for 2021 Lexus RX450hs

Enhance your 2021 Lexus RX450h with this popular Drive and Prop Shaft Assembly we have in stock, for $851.99.

Cardone – Drive Shaft: Not Greasable, Direct Replacement (Part No.65-5042)

Drive Shaft: Not Greasable, Direct Replacement

from

$851.99
CARDONE Remanufactured Prop Shafts are engineered using the most stringent quality processes to deliver smooth, consistent performance in any driving condition. Original designs are scrutinized for potential improvement, and where applicable, design upgrades are implemented to produce a more durable part than the original. All critical components are tested to ensure proper function. Additionally, all CARDONE Prop Shafts are 100 percent dynamically balanced, resulting in vibration-free performance at all speeds.

Product Features:
  • Built to match O.E. form, fit and function.
  • 100 percent NEW universal joints are installed to ensure proper fit and optimal performance.
  • All slip yokes are lubricated to prevent premature wear.
  • Units are 100 percent dynamically balanced at 3200 RPMs for vibration-free operation and increased joint life.
See More

Best-Selling 2021 Lexus RX450h Drive Shaft and Axle

Upgrade your RX450h with our best-selling Drive Shaft and Axle.

Carquest Premium – New CV Axle Assembly (Part No.NCV902651)

New CV Axle Assembly

from

$119.99
Manufactured to be an OE replacement, CV axles use 100% new materials and are engineered for ease of installation and long service.

Product Features:
  • All New Materials
  • Engineered for OE Fitment
  • -40 Degree Rated CV Boots
  • Moly-Blend Grease in inner and outer joints
  • New nut and mounting hardware included if required
See More

FAQs for 2021 Lexus RX450h Drive Shafts and Axles

What are the best-selling Drive Shafts and Axles for 2021 Lexus RX450hs?

Out of 2 Drive Shafts and Axles that fit 2021 Lexus RX450hs, the following parts are the top sellers:

What’s the price range for 2021 Lexus RX450h Drive Shafts and Axles?

The prices of Drive Shafts and Axles for the 2021 Lexus RX450h range from $119.99 up to $851.99 for the most premium parts.

What is the average price of a Drive Shafts and Axle for a 2021 Lexus RX450h?

The average price for Drive Shafts and Axles for the 2021 Lexus RX450h is $485.99. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drive Shafts and Axles for other Lexus RX450h model years?

Yes, we carry Drive Shafts and Axles for 11 model years of Lexus RX450hs between 2010 and 2022. The following model years are the most popular for Drive Shafts and Axle purchases: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Drive Shafts and Axles for my 2021 Lexus RX450h?

The cheapest 2021 Lexus RX450h Drive Shafts and Axles we carry are:

Does Advance Auto Parts sell Drive Shafts and Axles for any other 2021 Lexus models?

Yes. We stock Drive Shafts and Axles for 8 other popular 2021 Lexus models. Some of the most popular are 2021 RX350 Drive Shafts and Axles, 2021 GX460 Drive Shafts and Axles, 2021 ES250 Drive Shafts and Axles, 2021 IS300 Drive Shafts and Axles, and 2021 IS350 Drive Shafts and Axles.

What types of Drive Shafts and Axles do you sell for my 2021 Lexus RX450h?

As of 11/2/25, these are some of the most in-demand types of Drive Shafts and Axles for a 2021 Lexus RX450h:

Can I get help with 2021 Lexus RX450h Drive Shafts and Axle orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Drive Shafts and Axles and more.

What is your return policy for Lexus RX450h Drive Shafts and Axles?

Advance Auto Parts keeps returns simple. For new Lexus RX450h Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.