2021 Lexus IS300 Engine Cooling Parts
Keep Your 2021 Lexus IS300 in Top Shape with Quality Engine Cooling Parts
Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2021 Lexus IS300 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Thermostats, Coolant Reservoir Caps, and Coolant Temperature Sensors. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.
Top-Rated Engine Cooling Parts from Trusted Brands
Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium. For example, Carquest Premium Engine Cooling Parts start at just $10.99 with an average 4.4 star rating. With over 8 reviews and a solid 4 star average, you can shop with confidence knowing other Lexus IS300 owners approve.
Competitive Prices and Extensive Inventory
The average price for a 2021 Lexus IS300 Engine Cooling Part at Advance Auto Parts is around $161.89, with a range that starts at $10.99 and goes up to $453.99. With 9 options in stock from 4 trusted brands, finding the right fit is easy. Popular picks like Radiator, Standard Thermostat: 172 Degrees, and Radiator Fan Assembly: Dual, Cost Effective and Reliable start at just $64.99 and offer a great balance of form and function.
Explore Related Parts
While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Air Conditioning Parts and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2021 Lexus IS300 in peak condition, inside and out.
Find Your Specific 2021 Lexus IS300 Engine Cooling Parts
Looking for the perfect Engine Cooling Part for your 2021 Lexus IS300? You’re in the right place. Below, you’ll find links to various types of Engine Cooling Parts that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Engine Cooling Parts, ensuring durability and a precise fit for your Lexus IS300. Whether you’re driving a 2021 model or another popular model year like
2003,
2004,
2005,
2016,
2017,
2018,
2019,
2020, and
2022, we’ve got you covered. Purchasing Engine Cooling Parts from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Engine Cooling Parts that fit your vehicle.
Essential 2021 Lexus IS300 Engine Cooling Parts
Carquest Premium – Aux Water Pump (Part No.T1725)
from
$429.99
Aux Water Pump
Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-498)
from
$453.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.
Product Features:
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Product Features:
- Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
- Complete package – assembly is designed with the same materials and components as the original part
- Quality assured – motors are tested in laboratory settings to ensure performance
- Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)
from
$10.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.
Product Features:
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Product Features:
- Maintains proper cooling system pressure
- Easy installation and removal
- 100% tested to ensure proper pressure and longevity
- Meets all OEM specifications
Carquest Premium – Radiator Cap: 16 PSI (Part No.10242)
from
$16.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.
Product Features:
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Product Features:
- Maintains proper cooling system pressure
- Easy installation and removal
- 100% tested to ensure proper pressure and longevity
- Meets all OEM specifications
Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.432635)
from
$297.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.
Product Features:
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Product Features:
- Thermal tested under real-life temperature simulations
- High tensile strength aluminum for maximum crimp strength
- Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
- Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
Carquest Premium – Radiator (Part No.813477)
from
$178.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.
Product Features:
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Product Features:
- Thermal tested under real-life temperature simulations
- High tensile strength aluminum for maximum crimp strength
- Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
- Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
Factory Air – Coolant Temp Sensor Switch (Part No.36424)
from
$34.05
High quality OE replacement part with all components needed to complete the job
Product Features:
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Product Features:
- Contains gaskets, O-rings, or seals to properly replace the product
- Brass construction for accurate temperature sensing
- Color coded for easy identification
- Zinc coated terminal to resist corrosion
Delphi – Engine Coolant Temperature Sensor (Part No.TS10198)
from
$41.49
Delphi’s history is one of OE heritage and quality. Our global technical requirements include design specifications and validation testing based on over 100 years of OE experience. Our material selections, material thickness, and material types are built from OE specifications to exceed aftermarket expectations. We put in place strict manufacturing processes to ensure quality control in every part we make. Delphi’s pioneering spirit delivers innovative solutions designed to support the aftermarket in servicing the vehicles of today, and tomorrow.
Product Features:
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Product Features:
- Delphi temperature sensors deliver accurate readings and optimal performance
- Delphi’s one-piece design and automated production process eliminates internal connectors and failure points
- Each sensor is electrically insulated to eliminate interference from other components in the vehicle
- Delphi temperature sensors are impervious to electrical noise and interference
DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)
from
$99.99
DENSO’s engine coolant temperatures sensors are manufactured to the strictest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.
Product Features:
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Product Features:
- OE technology adapted for the aftermarket
- Reduces emissions, increased performance
- Delivers the highest reliability and detection accuracy
Carquest Premium – Coolant Temperature Sensor 1TS1172 (Part No.WTC2071)
from
$65.99
Product Features:
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- Designed to meet or exceed OE specifications for fit, form and function
- 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
- OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
- O-rings, seals or thread sealant are included if required
- Weather-tight connectors prevent leaks and corrosion for longer life
- Extensive design validation testing and 100% end-of-line tested
- Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8001)
from
$36.99
TEMPERATURE SENSOR
AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8003)
from
$48.99
TEMPERATURE SENSOR
Motorad UltraStats – UltraStat Thermostat: 180 Degrees (Part No.5298-180)
from
$28.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.
Product Features:
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Product Features:
- Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
- Heavy gauge stainless steel components offer increased reliability and long-lasting durability
- Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
- AccuSpring Design for stable temperature control and increased cabin comfort
Carquest Premium – Standard Thermostat: 180 Degrees (Part No.14108)
from
$17.29
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: 180 Degrees (Part No.1065-180)
from
$114.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: 172 Degrees (Part No.1064-172)
from
$64.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: 140 Degrees (Part No.298-140)
from
$25.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
See More
Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Popular 2021 Lexus IS300 Engine Cooling Parts Categories
Most Popular Thermostats for 2021 Lexus IS300s
Enhance your 2021 Lexus IS300 with one of the 2 Thermostats we have in stock, starting at just $64.99.
Carquest Premium – Standard Thermostat: 180 Degrees (Part No.1065-180)
from
$114.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
See More
Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: 172 Degrees (Part No.1064-172)
from
$64.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
See More
Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Best-Selling 2021 Lexus IS300 Coolant Reservoir Cap
Upgrade your IS300 with our best-selling Coolant Reservoir Cap with a 4 Starts rating across 4 reviews.
Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)
from
$10.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.
Product Features:
See More
Product Features:
- Maintains proper cooling system pressure
- Easy installation and removal
- 100% tested to ensure proper pressure and longevity
- Meets all OEM specifications
Top-Quality Coolant Temperature Sensors for 2021 Lexus IS300s
Choose a high-quality OEM or aftermarket Coolant Temperature Sensor for Lexus IS300s and enjoy top-notch performance from $48.99.
DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)
from
$99.99
DENSO’s engine coolant temperatures sensors are manufactured to the strictest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.
Product Features:
See More
Product Features:
- OE technology adapted for the aftermarket
- Reduces emissions, increased performance
- Delivers the highest reliability and detection accuracy
Carquest Premium – Coolant Temperature Sensor 1TS1172 (Part No.WTC2071)
from
$65.99
Product Features:
See More
- Designed to meet or exceed OE specifications for fit, form and function
- 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
- OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
- O-rings, seals or thread sealant are included if required
- Weather-tight connectors prevent leaks and corrosion for longer life
- Extensive design validation testing and 100% end-of-line tested
- Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8003)
from
$48.99
TEMPERATURE SENSOR
Our Top Pick for a 2021 Lexus IS300 Radiator Fan Motor
Invest in a
durable Radiator Fan Motor for your 2021 Lexus, knowing you’re getting trusted brands and expert craftsmanship.
Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-498)
from
$453.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.
Product Features:
See More
Product Features:
- Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
- Complete package – assembly is designed with the same materials and components as the original part
- Quality assured – motors are tested in laboratory settings to ensure performance
- Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
Our Radiators for 2021 Lexus IS300s
Make a smart move for your 2021 Lexus IS300 with our Radiator for $317.99.
Carquest Premium – Radiator (Part No.4113912)
from
$317.99
A global leader in the manufacture and distribution of aftermarket cooling products for automotive, heavy truck, and industrial applications. Specialized in the production of OE-quality Radiators, Condensers, and Charge Air Coolers for US and international markets, covering over 10,000 part numbers worldwide.
Product Features:
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Product Features:
- We design and manufacture all our radiators to meet or even exceed Original Equipment specifications. We take pride in producing the most reliable replacement parts in the market.
- Thermal expansion cuts allow for longer life and reduced failure rates by allowing improved core expansion and contraction during normal heat cycles.
- Our B-Type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
- We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
- Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
- Our fin edges are folded for increased stability and heat disbursement properties.
- Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Top-Rated Engine Cooling Part Brands For Your 2021 Lexus IS300
When it comes to finding the perfect Engine Cooling Part for your 2021 Lexus IS300, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 4 trusted brands. We carry the most popular Engine Cooling Part brands including Carquest Premium, and more, all known for their exceptional customer ratings (average brand rating of 4.4 stars) and competitive prices, as low as $10.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2021 Lexus IS300, providing peace of mind with parts that meet or exceed OEM standards.
Popular Carquest Premium 2021 Lexus IS300 Engine Cooling Parts
If you’re looking for a top-quality Engine Cooling Part for your 2021 Lexus IS300, Advance Auto Parts has exactly what you need with our selection of Carquest Premium Engine Cooling Parts. We have 1 Carquest Premium Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $10.99, you’ll find the perfect Engine Cooling Part for your needs and budget. Carquest Premium Engine Cooling Parts for the 2021 Lexus IS300 come highly rated, with over 4 customer reviews and an impressive average rating of 4.4 stars. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
from
$10.99
(4)
Engine Coolant Reservoir Cap
“I had a difficult time finding a coolant reservoir cap for a Toyota Prius. Advance was the only place in town that carried them.”
FAQs for 2021 Lexus IS300 Engine Cooling Parts
What are the best-selling Engine Cooling Parts for 2021 Lexus IS300s?
Out of 9 Engine Cooling Parts that fit 2021 Lexus IS300s, the following parts are the top sellers:
- Radiator (50301871) – $317.99
- Standard Thermostat: 172 Degrees (50042442) – $64.99
- Radiator Fan Assembly: Dual, Cost Effective and Reliable (11438686) – $453.99
What’s the price range for 2021 Lexus IS300 Engine Cooling Parts?
The prices of Engine Cooling Parts for the 2021 Lexus IS300 range from $10.99 up to $453.99 for the most premium parts.
What is the average price of an Engine Cooling Part for a 2021 Lexus IS300?
The average price for Engine Cooling Parts for the 2021 Lexus IS300 is $161.89. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Engine Cooling Parts for other Lexus IS300 model years?
What are the cheapest Engine Cooling Parts for my 2021 Lexus IS300?
The cheapest 2021 Lexus IS300 Engine Cooling Parts we carry are:
- Engine Coolant Reservoir Cap (15480044) – $10.99
- TEMPERATURE SENSOR (50260645) – $48.99
- Standard Thermostat: 172 Degrees (50042442) – $64.99
- Coolant Temperature Sensor 1TS1172 (12422985) – $65.99
- Engine Coolant Temperature Sensor (10888028) – $99.99
Does Advance Auto Parts sell Engine Cooling Parts for any other 2021 Lexus models?
Yes. We stock Engine Cooling Parts for 11 other popular 2021 Lexus models. Some of the most popular are 2021 ES350 Engine Cooling Parts, 2021 RX350 Engine Cooling Parts, 2021 GX460 Engine Cooling Parts, 2021 ES250 Engine Cooling Parts, and 2021 IS350 Engine Cooling Parts.
What types of Engine Cooling Parts do you sell for my 2021 Lexus IS300?
As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2021 Lexus IS300:
Can I get help with 2021 Lexus IS300 Engine Cooling Part orders?
Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Engine Cooling Parts and more.
What is your return policy for Lexus IS300 Engine Cooling Parts?
Advance Auto Parts keeps returns simple. For new Lexus IS300 Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.