2021 Lexus ES250 Lubricants

Please Select your Vehicle to See Exact Fit Parts

Keep Your 2021 Lexus ES250 in Top Shape with Quality Lubricants

Whether you’re repairing or upgrading your Lubricant, using high-quality parts is key to keeping your 2021 Lexus ES250 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Gear Oil and Final Drive Oil. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2021 Lexus ES250 Lubricant at Advance Auto Parts is around $26.32, with a range that starts at $11.99 and goes up to $37.99. With 3 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like LIQUI MOLY 75W-90 Full Synthetic Gear Oil, Ensures Maximum Wear Protection, 1 Liter, 22090, Pennzoil 5W-30 Full Synthetic Motor Oil, Helps Prevent Sludge Build-Up, 5 Quart, 550058602, and Pennzoil Full Synthetic 5W-30 Motor Oil, Go Farther Between Oil Changes, 1 Quart, 550058600 start at just $11.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Lubricant, don’t forget to check out other key components like Motor Oil. At Advance Auto Parts, we’re here to help you keep your 2021 Lexus ES250 in peak condition, inside and out.

Essential 2021 Lexus ES250 Lubricants

LIQUI MOLY – LIQUI MOLY 75W-90 Full Synthetic Gear Oil, Ensures Maximum Wear Protection, 1 Liter, 22090 (Part No.22090)

LIQUI MOLY 75W-90 Full Synthetic Gear Oil, Ensures Maximum Wear Protection, 1 Liter, 22090

from

$28.99
75W-90 Full Synthetic Gear Oil is engineered for high-performance applications, delivering exceptional reliability even under extreme loads and demanding operating conditions. Its fully synthetic composition ensures maximum wear protection, safeguarding critical components and extending the lifespan of your vehicle’s gear system. Designed to perform seamlessly across a wide temperature range, this gear oil promotes precise functionality, making it ideal for both everyday use and challenging environments. With industry-leading specifications and approvals, including API GL4, API GL5, and API MT-1, it meets rigorous standards for quality and compatibility. The advanced formula also enables longer oil change intervals, reducing maintenance frequency and providing excellent value for your investment. Perfect for drivers seeking durability, efficiency, and superior performance in a single solution.
See More

Valvoline – Valvoline High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon, 773732 (Part No.773732)

Valvoline High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon, 773732

from

$36.99
Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the No: 1 gear oil brand. Volume: 1 gallon.
See More

Valvoline – Valvoline High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Quart, VV831 (Part No.VV831)

Valvoline High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Quart, VV831

from

$13.99
Valvoline High Performance Gear Oil is an extreme pressure gear lubricant formulated with quality base oils and superior additives that helps protect against severe temperatures, shock loads, scuffing, scouring, corrosion and pitting in high speed, high load, high torque and high horsepower conditions. Volume: 1 quart.
See More

Castrol – Castrol GTX High Mileage 10W-30 Synthetic Blend Motor Oil, 1 Quart, 149D6C (Part No.149D6C)

Castrol GTX High Mileage 10W-30 Synthetic Blend Motor Oil, 1 Quart, 149D6C

from

$10.99
Castrol GTX High Mileage 10W-30 is specially formulated for vehicles with over 75,000 miles. It’s a synthetic blend engine oil formulated to provide Superior Protection in 7 Critical Areas including corrosion prevention, sludge control, timing and friction wear and unique protection for your emission system. As your vehicle ages, it becomes more prone to catalytic converter failure, one of the most common and costliest problems faced by higher mileage vehicles. All motor oil contains phosphorus to prevent engine wear, but phosphorus is known to be effectively poisonous to catalytic converters. Castrol GTX High Mileage 10W-30 is formulated with Phosphorous Replacement Technology, a proprietary additive that reduces the level of harmful phosphorus to protect the catalytic converter and preserve the life of your emission system. It also includes specialized additives to reduce leaks, oil burn off and power robbing deposits. Castrol GTX High Mileage 10W-30 provides maximum protection to help extend the life of your high mileage car. Volume: 1 quart.
See More

Castrol – Castrol EDGE High Mileage 10W-40 Advanced Full Synthetic Motor Oil, 1 Quart, 15989F (Part No.15989F)

Castrol EDGE High Mileage 10W-40 Advanced Full Synthetic Motor Oil, 1 Quart, 15989F

from

$13.99
Castrol EDGE High Mileage 10W-40 is the natural choice for drivers who demand maximum performance from their high mileage car. It’s been engineered to provide Superior Protection in 7 Crtitical Areas including corrosion prevention, sludge control, timing and friction wear and unique protection for your emission system. As your vehicle ages, it becomes more prone to catalytic converter failure. Castrol EDGE High Mileage is formulated with a with Phosphorous Replacement Technology, a proprietary additive that reduces the level of harmful phosphorus to protect the catalytic converter and preserve the life of your emission system. It’s full synthetic formula provides enhanced protection against extreme internal temperatures and also includes specialized additives to reduce leaks, oil burn off and power robbing deposits. Castrol EDGE High Mileage helps your car defy its miles and extend maximum performance. Volume: 1 quart.
See More

Mobil 1 – Mobil 1 High Mileage Full Synthetic Motor Oil 10W-30, 1 Quart, 14992 (Part No.14992)

Mobil 1 High Mileage Full Synthetic Motor Oil 10W-30, 1 Quart, 14992

from

$13.49
Mobil 1 High Mileage motor oil utilizes our signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles of all ages. Specialty components in synthetic oil extend engine life by reducing the friction that causes deposits and sludge buildup – keeping critical engine parts clean and protected for up to 15,000 miles between oil changes.(1) Mobil 1 High Mileage motor oil meets ILSAC GF-7 standards, offering superior oxidation control, enhanced protection against pre-ignition and timing chain wear, and excellent cold-start and low-temperature performance. Mobil 1 is the No. 1 selling motor oil in America at retail,(2) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR(R). Volume: 1 quart.
See More

Castrol – Castrol EDGE Euro 5W-30 A3/B4 Advanced Full Synthetic Motor Oil, 5 Quarts, 15D453 (Part No.15D453)

Castrol EDGE Euro 5W-30 A3/B4 Advanced Full Synthetic Motor Oil, 5 Quarts, 15D453

from

$44.99
Castrol EDGE Euro 5W-30 A3/B4 is an advanced full synthetic motor oil engineered to exceed manufacturer test limits ensuring the highest level of protection and maximum performance for European cars. European car manufacturers create unique motor oil specifications to ensure the lubricant can withstand the intense pressure, heat and friction generated in a high output engine. To ensure compliance, rigorous engine tests are developed, with approval granted only when the oil achieves the minimum values required in each test. Castrol EDGE Euro Car fluids are formulated to exceed these requirements and deliver maximum protection and performance. Volume: 5 quarts.
See More

Mobil 1 – Mobil 1 High Mileage Full Synthetic Motor Oil 5W-30, 5 Quart, 120769 (Part No.120769)

Mobil 1 High Mileage Full Synthetic Motor Oil 5W-30, 5 Quart, 120769

from

$42.99
Mobil 1 High Mileage motor oil utilizes our signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles of all ages. Specialty components in synthetic oil extend engine life by reducing the friction that causes deposits and sludge buildup – keeping critical engine parts clean and protected for up to 15,000 miles between oil changes.(1) Mobil 1 High Mileage motor oil meets ILSAC GF-7 standards, offering superior oxidation control, enhanced protection against pre-ignition and timing chain wear, and excellent cold-start and low-temperature performance. Mobil 1 is the No. 1 selling motor oil in America at retail,(2) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR(R). Volume: 5 quarts.
See More

Pennzoil – Pennzoil 5W-30 Full Synthetic Motor Oil, Helps Prevent Sludge Build-Up, 5 Quart, 550058602 (Part No.550058602)

Pennzoil 5W-30 Full Synthetic Motor Oil, Helps Prevent Sludge Build-Up, 5 Quart, 550058602

from

$37.99
Pennzoil 5W-30 Full Synthetic motor oil is designed to let you go farther between oil changes. It provides better engine protection and is backed by a 10,000-mile protection guarantee to give you peace of mind that your engine is protected now and for all the miles ahead. Pennzoil Full Synthetic motor oil is formulated for longer drain intervals than conventional and synthetic blend motor oils, offers enhanced wear protection in high and low temperatures, provides excellent resistance to oil breakdown in severe environments, and helps prevent sludge and deposit build-up. Suitable for both new and old engines. (Compared to Pennzoil motor oil. Pennzoil Full Synthetic Lubrication Limited Warranty: Protection for up to 10,000 miles or one year, whichever comes first. Use an oil filter designed for longer oil change intervals and follow OEM manual and vehicles oil life sensor to maintain OEM warranty. Excludes severe driving conditions, including racing and commercial use. Your engine must have fewer than 125,000 miles and have been manufactured in the past 72 months. Enrollment required. Other conditions apply. See pennzoil.com/warranty to enroll and for full details and terms.) Volume: 5 quarts.
See More

Castrol – Castrol GTX 10W-30 Premium Conventional Motor Oil, 5 Quarts, 15B7AA (Part No.15B7AA)

Castrol GTX 10W-30 Premium Conventional Motor Oil, 5 Quarts, 15B7AA

from

$35.99
Castrol GTX 10W-30 provides superior sludge protection to help extend engine life. Severe driving conditions such as heavy traffic, poor fuel quality, harsh driving conditions and exceeding oil change intervals can all cause the build-up of a thick, tar like substance called sludge. Sludge can block your engine’s vital oilways like cholesterol and if untreated, can rob an engine of its power and ultimately its life. Castrol GTX is specially engineered to prevent harmful build-up of sludge while protecting against new oil splatter formation better than tough industry standards. Volume: 5 quarts.
See More

Castrol – Castrol EDGE High Mileage 10W-30 Advanced Full Synthetic Motor Oil,1 Quart, 15979B (Part No.15979B)

Castrol EDGE High Mileage 10W-30 Advanced Full Synthetic Motor Oil,1 Quart, 15979B

from

$13.99
Castrol EDGE High Mileage 10W-30 is the natural choice for drivers who demand maximum performance from their high mileage car. It’s been engineered to provide Superior Protection in 7 Crtitical Areas including corrosion prevention, sludge control, timing and friction wear and unique protection for your emission system. As your vehicle ages, it becomes more prone to catalytic converter failure. Castrol EDGE High Mileage is formulated with a with Phosphorous Replacement Technology, a proprietary additive that reduces the level of harmful phosphorus to protect the catalytic converter and preserve the life of your emission system. It’s full synthetic formula provides enhanced protection against extreme internal temperatures and also includes specialized additives to reduce leaks, oil burn off and power robbing deposits. Castrol EDGE High Mileage helps your car defy its miles and extend maximum performance. Volume: 1 quart.
See More

Mobil 1 – Mobil 1 Advanced Full Synthetic Motor Oil 5W-30, 5 Quart, 44899 (Part No.44899)

Mobil 1 Advanced Full Synthetic Motor Oil 5W-30, 5 Quart, 44899

from

$42.99
Mobil 1 motor oil utilizes our signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles of all ages. Specialty components in synthetic oil extend engine life by reducing the friction that causes deposits and sludge buildup – keeping critical engine parts clean and protected for up to 15,000 miles between oil changes.(1) Mobil 1 motor oil meets ILSAC GF-7 standards, offering superior oxidation control, enhanced protection against pre-ignition and timing chain wear, and excellent cold-start and low-temperature performance. Mobil 1 is the No. 1 selling motor oil in America at retail,(2) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR(R). (1)Protects for 15,000 miles or 1 year, whichever comes first (2)Source: Circana/ Retail Tracking Service/ Dollar Sales/ 52 weeks ending February 1, 2025 Volume: 5 quarts.
See More

Quaker State – Quaker State Full Synthetic 0W-20 Motor Oil, Maximizes Horsepower, 1 Quart, 550046176 (Part No.550046176)

Quaker State Full Synthetic 0W-20 Motor Oil, Maximizes Horsepower, 1 Quart, 550046176

from

$9.49
Quaker State Full Synthetic 0W-20 motor oil provides strong engine performance for today€™s technologically advanced engines and high-performance vehicles. It’s if you exclusively use Quaker State Full Synthetic and Quaker State motor oils. Quaker State is the only warranty program that pays back the Kelley Blue Book trade-in value of your car for up to 3,000 dollars. Volume: 1 quart.
See More

Castrol – Castrol TranSynd 668 Full Synthetic Automatic Transmission Fluid, 1 Gallon, 15E2E1 (Part No.15E2E1)

Castrol TranSynd 668 Full Synthetic Automatic Transmission Fluid, 1 Gallon, 15E2E1

from

$59.99
TranSynd 668 Full Synthetic Transmission Fluid is engineered to deliver exceptional performance and durability for your vehicle’s transmission system. Designed with advanced features, it ensures improved gear protection and extended clutch-friction durability, making it ideal for both general-duty and severe-duty transmissions. With the ability to support extended drain intervals of up to 300,000 miles or 48 months in general-duty use and up to 150,000 miles or 48 months in severe-duty conditions, this fluid offers outstanding value and reduced maintenance downtime. Its excellent shear stability maintains consistent viscosity, providing reliable wear protection throughout the drain interval. Additionally, the fluid’s superior thermal and oxidation stability minimizes deposit formation, while its full-synthetic base ensures optimal performance across a wide temperature range. Enhanced corrosion and foaming resistance further contribute to the longevity and efficiency of your transmission system. Packaged in a convenient 1-gallon container, TranSynd 668 is the ultimate choice for those seeking high-performance, long-lasting transmission fluid. Volume: 1 gallon.
See More

Pennzoil – Pennzoil Full Synthetic 5W-30 Motor Oil, Go Farther Between Oil Changes, 1 Quart, 550058600 (Part No.550058600)

Pennzoil Full Synthetic 5W-30 Motor Oil, Go Farther Between Oil Changes, 1 Quart, 550058600

from

$11.99
Pennzoil 5W-30 Full Synthetic motor oil is designed to let you go farther between oil changes. It provides better engine protection and is backed by a 10,000-mile protection guarantee to give you peace of mind that your engine is protected now and for all the miles ahead. Pennzoil Full Synthetic motor oil is formulated for longer drain intervals than conventional and synthetic blend motor oils, offers enhanced wear protection in high and low temperatures, provides excellent resistance to oil breakdown in severe environments, and helps prevent sludge and deposit build-up. Suitable for both new and old engines. (Compared to Pennzoil motor oil. Pennzoil Full Synthetic Lubrication Limited Warranty: Protection for up to 10,000 miles or one year, whichever comes first. Use an oil filter designed for longer oil change intervals and follow OEM manual and vehicles oil life sensor to maintain OEM warranty. Excludes severe driving conditions, including racing and commercial use. Your engine must have fewer than 125,000 miles and have been manufactured in the past 72 months. Enrollment required. Other conditions apply. See pennzoil.com/warranty to enroll and for full details and terms.) Volume: 1 quart.
See More

Most Popular Gear Oil for 2021 Lexus ES250s

Enhance your 2021 Lexus ES250 with one of the 2 Gear Oil we have in stock, starting at just $11.99.

Pennzoil – Pennzoil 5W-30 Full Synthetic Motor Oil, Helps Prevent Sludge Build-Up, 5 Quart, 550058602 (Part No.550058602)

Pennzoil 5W-30 Full Synthetic Motor Oil, Helps Prevent Sludge Build-Up, 5 Quart, 550058602

from

$37.99
Pennzoil 5W-30 Full Synthetic motor oil is designed to let you go farther between oil changes. It provides better engine protection and is backed by a 10,000-mile protection guarantee to give you peace of mind that your engine is protected now and for all the miles ahead. Pennzoil Full Synthetic motor oil is formulated for longer drain intervals than conventional and synthetic blend motor oils, offers enhanced wear protection in high and low temperatures, provides excellent resistance to oil breakdown in severe environments, and helps prevent sludge and deposit build-up. Suitable for both new and old engines. (Compared to Pennzoil motor oil. Pennzoil Full Synthetic Lubrication Limited Warranty: Protection for up to 10,000 miles or one year, whichever comes first. Use an oil filter designed for longer oil change intervals and follow OEM manual and vehicles oil life sensor to maintain OEM warranty. Excludes severe driving conditions, including racing and commercial use. Your engine must have fewer than 125,000 miles and have been manufactured in the past 72 months. Enrollment required. Other conditions apply. See pennzoil.com/warranty to enroll and for full details and terms.) Volume: 5 quarts.
See More

Pennzoil – Pennzoil Full Synthetic 5W-30 Motor Oil, Go Farther Between Oil Changes, 1 Quart, 550058600 (Part No.550058600)

Pennzoil Full Synthetic 5W-30 Motor Oil, Go Farther Between Oil Changes, 1 Quart, 550058600

from

$11.99
Pennzoil 5W-30 Full Synthetic motor oil is designed to let you go farther between oil changes. It provides better engine protection and is backed by a 10,000-mile protection guarantee to give you peace of mind that your engine is protected now and for all the miles ahead. Pennzoil Full Synthetic motor oil is formulated for longer drain intervals than conventional and synthetic blend motor oils, offers enhanced wear protection in high and low temperatures, provides excellent resistance to oil breakdown in severe environments, and helps prevent sludge and deposit build-up. Suitable for both new and old engines. (Compared to Pennzoil motor oil. Pennzoil Full Synthetic Lubrication Limited Warranty: Protection for up to 10,000 miles or one year, whichever comes first. Use an oil filter designed for longer oil change intervals and follow OEM manual and vehicles oil life sensor to maintain OEM warranty. Excludes severe driving conditions, including racing and commercial use. Your engine must have fewer than 125,000 miles and have been manufactured in the past 72 months. Enrollment required. Other conditions apply. See pennzoil.com/warranty to enroll and for full details and terms.) Volume: 1 quart.
See More

Best-Selling 2021 Lexus ES250 Final Drive Oil

Upgrade your ES250 with our best-selling Final Drive Oil.

LIQUI MOLY – LIQUI MOLY 75W-90 Full Synthetic Gear Oil, Ensures Maximum Wear Protection, 1 Liter, 22090 (Part No.22090)

LIQUI MOLY 75W-90 Full Synthetic Gear Oil, Ensures Maximum Wear Protection, 1 Liter, 22090

from

$28.99
75W-90 Full Synthetic Gear Oil is engineered for high-performance applications, delivering exceptional reliability even under extreme loads and demanding operating conditions. Its fully synthetic composition ensures maximum wear protection, safeguarding critical components and extending the lifespan of your vehicle’s gear system. Designed to perform seamlessly across a wide temperature range, this gear oil promotes precise functionality, making it ideal for both everyday use and challenging environments. With industry-leading specifications and approvals, including API GL4, API GL5, and API MT-1, it meets rigorous standards for quality and compatibility. The advanced formula also enables longer oil change intervals, reducing maintenance frequency and providing excellent value for your investment. Perfect for drivers seeking durability, efficiency, and superior performance in a single solution.
See More

FAQs for 2021 Lexus ES250 Lubricants

What are the best-selling Lubricants for 2021 Lexus ES250s?

What’s the price range for 2021 Lexus ES250 Lubricants?

The prices of Lubricants for the 2021 Lexus ES250 range from $11.99 up to $37.99 for the most premium parts.

What is the average price of a Lubricant for a 2021 Lexus ES250?

The average price for Lubricants for the 2021 Lexus ES250 is $26.32. Keep in mind the variety of part types within our Lubricant category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Lubricants for other Lexus ES250 model years?

Yes, we carry Lubricants for 5 model years of Lexus ES250s between 1990 and 2025. The following model years are the most popular for Lubricant purchases: 1991, 1990, 2025, 2023, 2024, and 2022.

What are the cheapest Lubricants for my 2021 Lexus ES250?

Does Advance Auto Parts sell Lubricants for any other 2021 Lexus models?

Yes. We stock Lubricants for 11 other popular 2021 Lexus models. Some of the most popular are 2021 GX460 Lubricants, 2021 IS300 Lubricants, 2021 IS350 Lubricants, 2021 RC350 Lubricants, and 2021 RC300 Lubricants.

What types of Lubricants do you sell for my 2021 Lexus ES250?

As of 8/2/26, these are some of the most in-demand types of Lubricants for a 2021 Lexus ES250:

Can I get help with 2021 Lexus ES250 Lubricant orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Lubricants and more.

What is your return policy for Lexus ES250 Lubricants?

Advance Auto Parts keeps returns simple. For new Lexus ES250 Lubricants and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.