2021 GMC Sierra 2500 HD Transmission Parts

Essential Transmission Parts for 2021 GMC Sierra 2500 HDs

ACDelco – AT Neutral Safety Sw (Part No.J4050485851ACD)

AT Neutral Safety Sw

from

$82.58
AT Neutral Safety Sw

ACDelco – Neutral Safety Switc (Part No.J4050351665ACD)

Neutral Safety Switc

from

$146.10
Neutral Safety Switc

Carquest Premium – Back Up Light Switch (Part No.NSE1016)

Back Up Light Switch

from

$81.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Dorman – Help – Transmission Oil Cooler Seal (Part No.66219)

Transmission Oil Cooler Seal

from

$11.49
This Dorman Automatic Transmission Oil Cooler Gasket eliminates leaks where the oil cooler line connects to the transmission. Gasket may break down over time, causing leaks, and should be replaced any time the oil cooler line and transmission are separated.

Product Features:
  • Durable construction – rubber over steel construction creates a positive seal and retains its shape.
  • Direct replacement – fits and functions like original equipment
  • Easy to install – direct-fit, no special tools required
  • Vehicle tested – has undergone on-vehicle testing to ensure proper fit and performance
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ATP – AT EXT HOUSING SEAL (Part No.JO-57)

AT EXT HOUSING SEAL

from

$7.99
AT EXT HOUSING SEAL

ACDelco – AT Extension Housing (Part No.J5071587500ACD)

AT Extension Housing

from

$8.37
AT Extension Housing

National – Multi Purpose Seal (Part No.2457)

Multi Purpose Seal

from

$31.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
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ACDelco – AT Valve Body Separa (Part No.J5028745013ACD)

AT Valve Body Separa

from

$35.04
AT Valve Body Separa

SKF – AT Rear Seal (Part No.J5071366796SKF)

AT Rear Seal

from

$24.83
AT Rear Seal

ACDelco – AT Rear Seal (Part No.J5071366796ACD)

AT Rear Seal

from

$35.49
AT Rear Seal

Driveworks – Auto Transmission Output Shaft Seal (Part No.S-4934)

Auto Transmission Output Shaft Seal

from

$8.49
Product Features:
  • Brand may vary by location
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ACDelco – AT Pan Gasket (Part No.J5040366488ACD)

AT Pan Gasket

from

$47.15
AT Pan Gasket

ATP – AT OIL PAN GASKET (Part No.JG-107)

AT OIL PAN GASKET

from

$9.99
AT OIL PAN GASKET

Mahle – AT Pan Gasket (Part No.J5040577055MAH)

AT Pan Gasket

from

$27.20
AT Pan Gasket

Felpro – Transmission Oil Pan Gasket 17 Bolt Hole One Piece Gasket (Part No.TOS 18698)

Transmission Oil Pan Gasket 17 Bolt Hole One Piece Gasket

from

$15.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Unsurpassed quality you can trust
  • Validated for fit, form and function
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
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Shift Pro by ETE – 1000/M74 Automatic Transmission Assembly (Part No.T281233)

1000/M74 Automatic Transmission Assembly

from

$4046.99
At Shift Pro Inc, fully remanufactured transmissions go beyond the name. So, what’s in that name to start? Pro Engineering: your transmission has been re-engineered to meet or exceed OE standards for tolerances, durability, and quality. Pro Performance: upgraded components and a fully remanufactured torque converter add to enhanced durability over your transmission’s lifetime. Pro Performance: hot-, cold-, load-, and simulated road-tested on custom dynamometers, your transmission is ready to go, wherever you’re headed.

Product Features:
  • Fully tested torque converter included. Shift Pro Inc tests for leaks, lock-up, concentricity, and balance to eliminate the possibilities of front seal leaks, premature bushing wear, and vibration.
  • All dynamometer testing is conducted with Shift Pro Inc’s custom testing program for at least 30 minutes.
  • During dynamometer testing, Shift Pro Inc transmissions are cold, hot, load, and road tested using a fully synthetic transmission fluid and filtration system.
  • All wear-prone valves in the completely remanufactured valve body are restored to stringent specifications and vacuum tested to verify proper function.
  • Shift Pro Inc’s quality control process includes build specification checks performed by four different specialized technicians during the remanufacturing process.
  • No paperwork or registration is required with Shift Pro Inc’s warranty. Each no-hassle warranty is attached to the vehicle VIN and transferrable with ownership.
  • Product might not be available in all states due to local laws.
See More

Shift Pro by ETE – 1000/M74 Automatic Transmission Assembly (Part No.T281212)

1000/M74 Automatic Transmission Assembly

from

$3122.99
At Shift Pro Inc, fully remanufactured transmissions go beyond the name. So, what’s in that name to start? Pro Engineering: your transmission has been re-engineered to meet or exceed OE standards for tolerances, durability, and quality. Pro Performance: upgraded components and a fully remanufactured torque converter add to enhanced durability over your transmission’s lifetime. Pro Performance: hot-, cold-, load-, and simulated road-tested on custom dynamometers, your transmission is ready to go, wherever you’re headed.

Product Features:
  • Fully tested torque converter included. Shift Pro Inc tests for leaks, lock-up, concentricity, and balance to eliminate the possibilities of front seal leaks, premature bushing wear, and vibration.
  • All dynamometer testing is conducted with Shift Pro Inc’s custom testing program for at least 30 minutes.
  • During dynamometer testing, Shift Pro Inc transmissions are cold, hot, load, and road tested using a fully synthetic transmission fluid and filtration system.
  • All wear-prone valves in the completely remanufactured valve body are restored to stringent specifications and vacuum tested to verify proper function.
  • Shift Pro Inc’s quality control process includes build specification checks performed by four different specialized technicians during the remanufacturing process.
  • No paperwork or registration is required with Shift Pro Inc’s warranty. Each no-hassle warranty is attached to the vehicle VIN and transferrable with ownership.
  • Product might not be available in all states due to local laws.
See More

Shift Pro by ETE – 1000/M74 Automatic Transmission Assembly (Part No.T281214)

1000/M74 Automatic Transmission Assembly

from

$4046.99
At Shift Pro Inc, fully remanufactured transmissions go beyond the name. So, what’s in that name to start? Pro Engineering: your transmission has been re-engineered to meet or exceed OE standards for tolerances, durability, and quality. Pro Performance: upgraded components and a fully remanufactured torque converter add to enhanced durability over your transmission’s lifetime. Pro Performance: hot-, cold-, load-, and simulated road-tested on custom dynamometers, your transmission is ready to go, wherever you’re headed.

Product Features:
  • Fully tested torque converter included. Shift Pro Inc tests for leaks, lock-up, concentricity, and balance to eliminate the possibilities of front seal leaks, premature bushing wear, and vibration.
  • All dynamometer testing is conducted with Shift Pro Inc’s custom testing program for at least 30 minutes.
  • During dynamometer testing, Shift Pro Inc transmissions are cold, hot, load, and road tested using a fully synthetic transmission fluid and filtration system.
  • All wear-prone valves in the completely remanufactured valve body are restored to stringent specifications and vacuum tested to verify proper function.
  • Shift Pro Inc’s quality control process includes build specification checks performed by four different specialized technicians during the remanufacturing process.
  • No paperwork or registration is required with Shift Pro Inc’s warranty. Each no-hassle warranty is attached to the vehicle VIN and transferrable with ownership.
  • Product might not be available in all states due to local laws.
See More

Shift Pro by ETE – 1000/M74 Automatic Transmission Assembly (Part No.T281211)

1000/M74 Automatic Transmission Assembly

from

$3122.99
At Shift Pro Inc, fully remanufactured transmissions go beyond the name. So, what’s in that name to start? Pro Engineering: your transmission has been re-engineered to meet or exceed OE standards for tolerances, durability, and quality. Pro Performance: upgraded components and a fully remanufactured torque converter add to enhanced durability over your transmission’s lifetime. Pro Performance: hot-, cold-, load-, and simulated road-tested on custom dynamometers, your transmission is ready to go, wherever you’re headed.

Product Features:
  • Fully tested torque converter included. Shift Pro Inc tests for leaks, lock-up, concentricity, and balance to eliminate the possibilities of front seal leaks, premature bushing wear, and vibration.
  • All dynamometer testing is conducted with Shift Pro Inc’s custom testing program for at least 30 minutes.
  • During dynamometer testing, Shift Pro Inc transmissions are cold, hot, load, and road tested using a fully synthetic transmission fluid and filtration system.
  • All wear-prone valves in the completely remanufactured valve body are restored to stringent specifications and vacuum tested to verify proper function.
  • Shift Pro Inc’s quality control process includes build specification checks performed by four different specialized technicians during the remanufacturing process.
  • No paperwork or registration is required with Shift Pro Inc’s warranty. Each no-hassle warranty is attached to the vehicle VIN and transferrable with ownership.
  • Product might not be available in all states due to local laws.
See More

Anchor – Transmission Mount: Rear, 1 Piece (Part No.2638)

Transmission Mount: Rear, 1 Piece

from

$23.49
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to CADI 99-14; CHEV 82-19; GMC 82-14; HUMMER 03-10; ISUZU 06-08; OLDS 91-94;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 1982-2019
  • Weight approx: 5 Lbs
  • STUDS: M10-150
  • INTERLOCK
  • BOLT HOLES CENTERLINE: 7.5 INCH / 190.5 MM
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Anchor – Transmission Mount: Rear, 1 Piece (Part No.3264)

Transmission Mount: Rear, 1 Piece

from

$42.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to CHEV 11-16; GMC 11-16;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2011-2016
  • Weight approx: 4 Lbs
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Anchor – Transmission Mount: Rear, 1 Piece (Part No.2811)

Transmission Mount: Rear, 1 Piece

from

$17.49
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to CADI 00-20; CHEV 91-21; GMC 91-21;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 1991-2021
  • Weight approx: 2 Lbs
  • MATERIAL: RUBBER, STEEL
  • HEIGHT: 2.06 INCH / 52.32 MM
  • STUD: M10x1.5 1.15 INCH / 29.21 MM
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Anchor – Transmission Mount: Rear, 1 Piece (Part No.3278)

Transmission Mount: Rear, 1 Piece

from

$52.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to CADI 21-22; CHEV 11-22; GMC 11-22;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2011-2022
  • Weight approx: 2 Lbs
See More

ACDelco – AT Torque Conv. Hous (Part No.J5090577062ACD)

AT Torque Conv. Hous

from

$26.02
AT Torque Conv. Hous

Upgrade your 2021 GMC Sierra 2500 HD with Top-Quality Transmission Parts

When it comes to maintaining or upgrading your 2021 GMC Sierra 2500 HD, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Transmission Parts are key to keeping your Sierra 2500 HD functioning at its best. At Advance Auto Parts, we offer a wide selection of 10 Transmission Parts for the 2021 GMC Sierra 2500 HD, designed to meet your needs without breaking the bank. From Automatic Transmission Pan and Gasket replacements to Transmission Mounts upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Transmission Parts for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Transmission Parts for your 2021 GMC Sierra 2500 HD at great prices. Our Transmission Parts inventory for this model ranges from just $8.37 to $2,974.99, with an average price of $251.03. Our 10 Transmission Parts in stock come from 5 trusted brands, so you’re sure to find the right part for your 2021 GMC Sierra 2500 HD without overspending.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Transmission Part upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 GMC Sierra 2500 HD is always ready to roll. We’re committed to providing you with everything you need to keep your Sierra 2500 HD in top shape, all in one place. Start shopping confidently below for your 2021 GMC Sierra 2500 HD!

Best-Selling Automatic Transmission Pan and Gaskets for 2021 GMC Sierra 2500 HDs

Enhance the driving experience in your GMC with 2 quality Automatic Transmission Pan and Gasket components, starting at $11.49.

Dorman – Help – Transmission Oil Cooler Seal (Part No.66219)

Transmission Oil Cooler Seal

from

$11.49
This Dorman Automatic Transmission Oil Cooler Gasket eliminates leaks where the oil cooler line connects to the transmission. Gasket may break down over time, causing leaks, and should be replaced any time the oil cooler line and transmission are separated.

Product Features:
  • Durable construction – rubber over steel construction creates a positive seal and retains its shape.
  • Direct replacement – fits and functions like original equipment
  • Easy to install – direct-fit, no special tools required
  • Vehicle tested – has undergone on-vehicle testing to ensure proper fit and performance
See More

ACDelco – AT Pan Gasket (Part No.J5040366488ACD)

AT Pan Gasket

from

$47.15
AT Pan Gasket

Most Popular 2021 GMC Sierra 2500 HD Transmission Mounts

Customize your GMC with 1 Transmission Mounts products like Transmission Mounts, all priced under $52.99.

Anchor – Transmission Mount: Rear, 1 Piece (Part No.3278)

Transmission Mount: Rear, 1 Piece

from

$52.99
The purpose of the mount is to support the engine and transmission on the chassis and dampen vibration and noise from reverberating to the rest of the vehicle. Engine and Transmission Mounts are engineered and manufactured to meet or exceed OEM specifications using the latest CAD/CAM engineering process to ensure superior quality, form, fit and function. Only premium quality materials are used in the manufacturing process to guarantee precise performance and maximum durability. Applicable to CADI 21-22; CHEV 11-22; GMC 11-22;. Please verify your application.

Product Features:
  • MAXIMUM LIFE & PERFORMANCE: Both natural and SBR (Styrene Butadiene) rubber provide good abrasion resistance and aging stability to ensure maximum life and performance.
  • MEETS OR EXCEEDS DUROMETER MEASUREMENTS: All rubber material is manufactured to specific Durometer (hardness) measurements based on the vehicle’s application requirements.
  • HARDENED STEEL FASTENERS: All fasteners are made of hardened steel with heat treated Grade #5 bolts.
  • SUPERIOR BOND: A special Chemlock® bonding agent is used to ensure a superior rubber-to-metal bond.
  • HYDRAULIC MOUNT DESIGN: Hydraulic Mounts (applicable where OE) are designed for most front wheel drive vehicles because transverse drive train mounting.
  • For Years: 2011-2022
  • Weight approx: 2 Lbs
See More

Top Picks for 2021 GMC Sierra 2500 HD Transmission Seals

Upgrade GMC Sierra 2500 HDs with top-quality Transmission Seals parts, including 3 OEM and aftermarket selections for your 2021 model.

SKF – AT Rear Seal (Part No.J5071366796SKF)

AT Rear Seal

from

$24.83
AT Rear Seal

ACDelco – AT Rear Seal (Part No.J5071366796ACD)

AT Rear Seal

from

$35.49
AT Rear Seal

ACDelco – AT Extension Housing (Part No.J5071587500ACD)

AT Extension Housing

from

$8.37
AT Extension Housing

In-Demand Automatic Transmission Parts for 2021 GMC Sierra 2500 HDs

Select from 2 premium Automatic Transmission Parts parts for your 2021 GMC Sierra 2500 HD, with prices ranging from $35.04 to $2,974.99.

Shift Pro by ETE – 6L90 Automatic Transmission Assembly (Part No.T282139)

6L90 Automatic Transmission Assembly

from

$2974.99
At Shift Pro Inc, fully remanufactured transmissions go beyond the name. So, what’s in that name to start? Pro Engineering: your transmission has been re-engineered to meet or exceed OE standards for tolerances, durability, and quality. Pro Performance: upgraded components and a fully remanufactured torque converter add to enhanced durability over your transmission’s lifetime. Pro Performance: hot-, cold-, load-, and simulated road-tested on custom dynamometers, your transmission is ready to go, wherever you’re headed.

Product Features:
  • Fully tested torque converter included. Shift Pro Inc tests for leaks, lock-up, concentricity, and balance to eliminate the possibilities of front seal leaks, premature bushing wear, and vibration.
  • All dynamometer testing is conducted with Shift Pro Inc’s custom testing program for at least 30 minutes.
  • During dynamometer testing, Shift Pro Inc transmissions are cold, hot, load, and road tested using a fully synthetic transmission fluid and filtration system.
  • All wear-prone valves in the completely remanufactured valve body are restored to stringent specifications and vacuum tested to verify proper function.
  • Shift Pro Inc’s quality control process includes build specification checks performed by four different specialized technicians during the remanufacturing process.
  • No paperwork or registration is required with Shift Pro Inc’s warranty. Each no-hassle warranty is attached to the vehicle VIN and transferrable with ownership.
  • Product might not be available in all states due to local laws.
See More

ACDelco – AT Valve Body Separa (Part No.J5028745013ACD)

AT Valve Body Separa

from

$35.04
AT Valve Body Separa

Most Sold 2021 GMC Sierra 2500 HD Torque Converter and Related Products

Explore our best-selling GMC parts for the 2021 Sierra 2500 HD among 1 OEM and aftermarket options starting from $26.02.

ACDelco – AT Torque Conv. Hous (Part No.J5090577062ACD)

AT Torque Conv. Hous

from

$26.02
AT Torque Conv. Hous

FAQs for 2021 GMC Sierra 2500 HD Transmission Parts

Which Transmission Parts are best-sellers for 2021 GMC Sierra 2500 HDs?

Out of 10 Transmission Parts that fit 2021 GMC Sierra 2500 HDs, the following parts are the top sellers:

What’s the price range for 2021 GMC Sierra 2500 HD Transmission Parts?

Transmission Part prices for the 2021 GMC Sierra 2500 HD start at $8.37 and go up to $2,974.99 for the most premium parts.

What’s the average price of a Transmission Part for a 2021 GMC Sierra 2500 HD?

The average price for Transmission Parts for the 2021 GMC Sierra 2500 HD is $251.03. Keep in mind the variety of part types within our Transmission Part category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Transmission Parts for other GMC Sierra 2500 HD model years?

Yes, we currently carry Transmission Parts for 22 model years of GMC Sierra 2500 HDs between 2001 and 2024. Transmission Parts are bought most frequently for the following model years: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Transmission Parts for my 2021 GMC Sierra 2500 HD?

The cheapest 2021 GMC Sierra 2500 HD Transmission Parts we carry in stock are:

What types of Transmission Parts do you sell for my 2021 GMC Sierra 2500 HD?

Can I get help with 2021 GMC Sierra 2500 HD Transmission Part orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Transmission Parts and more.

What is your return policy for GMC Sierra 2500 HD Transmission Parts?

Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Transmission Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.