2021 GMC Sierra 2500 HD Engine Parts
Find Your Specific 2021 GMC Sierra 2500 HD Engine Parts
Below you will find various in-demand GMC Engine Parts, components and accessories for your 2021 Sierra 2500 HD. Advance Auto Parts has popular Sierra 2500 HD parts like Valve Cover and Cylinder Heads, Engine Gaskets and Seals, Engine Mounts and more. You’ll also find aftermarket and OEM Engine Parts for other Sierra 2500 HD model years including
2014,
2015,
2016,
2017,
2018,
2019,
2020,
2022,
2023 and more. Select a category of 2021 GMC Sierra 2500 HD Engine Parts below and start saving instantly.
Popular 2021 GMC Sierra 2500 HD Engine Parts Categories
Essential Engine Parts for 2021 GMC Sierra 2500 HDs
Spartan – Engine Long Block; GM 6.0 LS 11-13 HD Engine (Part No.VCT23HD)
from
$4279.99
Your remanufactured engine is tested in several specific ways after being assembled; Multiple Pressure tests. Each component is carefully checked after being cleaned to see if cracks or other defects exist in the casting. After being assembled, we pressure
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- Each engine we remanufacture is essentially reverse engineered – in part to discover original factory deficiencies. If possible, our seasoned R&D personnel & QC experts make improvements. Why shouldn’t our engine last longer than your First !
- Engines come with installation gasket set & oil pump unless noted otherwise. If we have important installation information it will be included on tags or in the paperwork packaged with your engine.
- Engines are securely packaged in a recyclable container that will also protect your core on the return trip. Our nationwide warehouse network means speedy delivery.
- Each engine is remanufactured with quality OE level components not “white” box generic parts that may or may not satisfy your needs and expectations. When you use the best you get the best results and satisfaction.
Carquest Premium – Manifold Absolute Pressure Sensor (Part No.WTA1591)
from
$49.99
Pressure sensors are used within several operating systems on the vehicle. Subjects in this category measure the pressure of both liquid and air to include air in a positive pressure and negative pressure range. Pressure sensors report out as the result of an electrical device called a strain gauge which produces an analog or digital signal output dependent on the needs of the circuit. Pressures may be very low such as barometric pressure, or extremely high such as in a high-pressure fuel injection system.
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- Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
- Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
- Robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
- Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
- 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
- 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
Felpro – Engine Oil Cooler Gasket (Part No.72435)
from
$7.49
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered and manufactured specifically for the repair environment
- Unsurpassed quality you can trust
- Includes all parts needed to complete the repair
Spartan – Engine Cylinder Head; Chevrolet 6.6 06-10 DRMX Head (Part No.2CX7)
from
$1134.99
Remanufactured Cylinder Heads are complete rebuild & include new valve stem seals, soft plugs & verified camshafts. All threads are checked and repaired if necessary. Cylinder Heads are packaged in heavy plastic to protect the unit.
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- All cylinder heads are both vacuum and pressure tested to verify valve seating, & integrity of water passages.
- All cylinder heads are packaged in environmentally safe and recyclable containers that are the perfect size for returning your original core
- All threads and machined surfaces are and repaired with technology that exceeds the original metal
- Non-sealing iron surfaces painted to prevent oxidization
Carquest Premium – Camshaft Sensor (Part No.CSC1064)
from
$63.99
A leader in vehicle electronic solutions, each premium product meets or exceeds OE specifications in appearance, fit, and function, ensuring easy installation and excellent performance. The product has been tested under extreme environments.
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- Reliable circuit board and product structure design, 3D proofing, and field test verification to ensure correct signal output at all speeds.
- Manufactured in an anti-static environment to ensure reliability and stability.
- Extreme temperature and salt spray tests simulate real-world vehicle conditions to ensure durability and reliability.
- Providing this premium product line, we meet the service professionals needs with the highest quality product every time the part comes out of the box.
Anchor – Engine Mount Front Left, Front Right (Part No.3211)
from
$91.99
Anchor 3211 This mount supports the engine and dampen vibration. Each mount is specifically engineered and designed to OE standards. Natural and SBR rubber provide maximum life and performance. Steel fasteners are heat treated grade 5 bolts. A special bonding agent is used to ensure a rubber to metal bond. Rubber material is mixed to specific Durometer, hardness.
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aFe POWER – Charge Pipe Kit (Part No.46-20114-B)
from
$545.99
BladeRunner charge tubes are designed to replace the factory intercooler tubes with a larger diameter and smoother flow path to reduce resistance and improve airflow. In addition, these tube upgrades incorporate NPT fittings for sensors and auxiliary input options.
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- Mandrel-bent powder-coated charge pipes improve performance and appeal
- Includes high-temp couplings and stainless steel t-bolt clamps
- Hassle Free Installation
- Works w/Stock Intercooler
Felpro – Fuel Pump Mounting Gasket (Part No.73158)
from
$5.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered for the sealing repair environment
- Unsurpassed quality you can trust
- Validated for fit, form, and function
Cloyes Performance – High Performance Timing Chain (Part No.9-131)
from
$88.99
High Performance 3/8″ Pitch Double Roller Replacement TRUE Roller Chain. 0.250″ Roller Diameter. Heat Treated and Processed Links to Maximize Ultimate Breaking Strength while Remaining Ductile for Toughness. Pre-stressed to Increase Fatigue Life.
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- A timing chain synchronizes the rotation of the crankshaft and camshaft(s), ensuring proper timing of the engines valve events for each cylinder
- Our chains are engineered and manufactured with precision pitch control for proper chain-to-sprocket tooth fitment
- From stock replacement to high performance, Cloyes has the most complete timing chain catalog
- Cloyes parts are CAD designed and manufactured using premium materials. Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
- Cloyes recommends the chain tensioner(s), sprocket(s), and guide(s) also be replaced when the chain is replaced as these components play a vital role in system stability and accurate timing
- Refer to our online catalog for detailed application-specific information
- Keep your engines valvetrain in perfect time with Cloyes, the world leader in timing drive systems
GM Genuine Parts – Gen III/IV Lifter Guide (Part No.12595365)
from
$14.99
GM Genuine Parts Engine Valve Lifter Guide are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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Product Features:
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
GM Genuine Parts – Oil Pan Seal (Part No.12621086)
from
$15.49
GM Genuine Parts Engine Oil Pan Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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Product Features:
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Carquest Premium – Engine Oil Level Sensor (Part No.SBC3719)
from
$50.99
The engine lubrication system is critical to engine operation and long life. On some vehicle applications, the engine control module monitors the engine oil level to ensure lubrication is not lost.
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- Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
- Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
- Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
- Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
- 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
- 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
Victor Reinz – Engine Oil Pan Gasket Set (Part No.10-10238-01)
from
$33.99
Built to meet or exceed the standards of original equipment manufacturers around the world and avoid comebacks Victor Reinz oil pan gaskets deliver the seal that prevents drops on the driveway. Victor Reinz engineers select the best designs and materials for the specific application. The level of sophistication in oil pan gasket form and function has jumped greatly in recent years, with the gasket often being an integral part of the manufacturers efforts to control engine noise, vibration, and harshness (NVH). Only a company with innovative gasket technology can supply the right gasket for every application, new or old.
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- Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
- Dana engineering-approved for fit, form and function.
- Meets or exceeds OE specifications.
Victor Reinz – Engine Cylinder Head Bolt Set (Part No.14-10117-01)
from
$102.99
Using new head bolts when performing a cylinder head installation is always a good idea however, on late-model engines that came from the factory with TTY (torque-to yield) head bolts, replacement is an absolute necessity. TTY bolts are designed to exert the maximum clamping force for a tight head gasket seal, however they permanently stretched and could fail if re-used.
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- Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
- Head bolt replacement recommended.
- Torque-to-yield bolts are designed so that they can be elongated beyond their elastic limit into the plastic region without problems.
- When a specific tightening torque has been reached, the bolts are turned further through a defined angle, which pre-loads them into the plastic region. Consequently, no retorquing is necessary.
Cloyes Gear – Engine Timing Crankshaft Sprocket (Part No.S837)
from
$32.99
Sprocket Made From High Alloy Material. Sprocket Teeth Are Heat Treated. Precision Tooth Form To Assure Proper Chain Engagement, And Precise Keyway To Tooth Timing.
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- Featuring precision-tooled or machined tooth form and precision-machined bore for true fit, timing chain sprockets offer reliability and dependability for engine rebuilds and typical replacement jobs
- Recommended that the chain tensioner(s), sprocket(s), and guide(s) also be replaced when the chain is replaced, as these components play a vital role in system stability and accurate timing
- CAD designed and manufactured using premium materials
- Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
- Refer to our online catalog for detailed application-specific information
Felpro – Engine Oil Dipstick Tube O-Ring (Part No.73889)
from
$0.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered for the sealing repair environment
- Validated for fit, form and function
- Unsurpassed quality you can trust
K&N – Oil Catch Can (Part No.81-0812)
from
$157.99
The K&N Air Oil Separator protects the engine and intake tract from blowby by capturing the oil in our industry leading high capacity reservoir. This helps prevent power loss and possible engine damage caused by blowby. The K&N Air Oil Separator is quick and easy to install in about 30 minutes with basic tools and uses factory-style hose connections to quickly snap on and off. The oil separator replaces the factory line from the crank case allowing the oil separator to be mounted to a coinvent location in your engine bay. No tools are needed to check and empty the oil collector reservoir. Each unit is engineered specifically for your vehicle and is backed by our No-Hassle Limited Warranty.
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Felpro – Engine Valve Cover Gasket Set (Part No.VS 50813 R)
from
$112.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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- DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
- ENGINEERED TO PERFORM – Proprietary cork-rubber formulation
- SUPERIOR SEAL – Highly conformable to accommodate for the imperfect sealing surfaces
- EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
- REAL WORLD TESTED – Parts are tested on-vehicle and validated to ensure optimal performance on the road
Felpro – Engine Camshaft Thrust Plate (Part No.ES 73115)
from
$42.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
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- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered for the sealing repair environment
- Validated for fit, form and function
- Unsurpassed quality you can trust
Cloyes Performance – High Performance Timing Set (Part No.9-3658TX3)
from
$215.99
Billet Crankshaft Sprocket Has Three Keyways for +/- 4 Degrees Adjustability. Both Billet Steel Sprockets are Heat Treated for Durability. TRUE Roller 0.250″ Roller Diameter Chain for Reduced Friction. Includes Captured Needle Camshaft Sprocket Thrust Bearing to Minimize Block Thrust Surface Friction. 3-Piece Sets Hand-Matched to Qualify the Correct Center Distance and Minimize Runout.
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- The complete kits, which meet or exceed OEM performance requirements, ensure a quiet and maintenance-free experience
- Cloyes parts are CAD designed and manufactured using premium materials. Each part is extensively tested and measured for function, fitment, and durability to ensure optimal performance
- Cloyes Timing Kits may include camshaft sprockets, crankshaft sprockets, timing chains, tensioners, and guides
- Refer to our online catalog for detailed application-specific information
- Keep your engine’s valve train in perfect time with Cloyes, the world leader in timing drive systems.
Melling Select Performance – Valve Train Set Up Spring (Part No.VTSS100)
from
$11.79
Melling Performance valvetrain checking springs feature a low-tension design that allows them to be installed by hand for measuring piston-to-valve clearance, rocker arm ratio, and degreeing in a camshaft.
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Victor Reinz – Engine Crankshaft Seal Kit (Part No.19-10080-01)
from
$45.49
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- Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
- Direct OEM replacement rotating shaft seal and edge molded metal plate retainer gasket
- Includes all components required to complete the repair.
- Dana engineering-approved for fit, form and function.
ACDelco – Air Pressure Sensor (Part No.12711681)
from
$76.99
ACDelco GM Original Equipment Multi Purpose Sensors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.
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- Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional
- ACDelco GM Original Equipment parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Sealed Power – Engine Valve Lifter (Part No.HT-2148A)
from
$24.99
Sealed Power® Vintage components provide coverage for applications over 35 years old, restoring classics with like new performance. Leading edge materials, ISO & QS certified manufacturing ensures performance and longevity for treasured engine rebuilds.
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- Unsurpassed quality that you can trust
- Uses leading edge materials
- State-of-the-art manufacturing
- Exacting tolerances
- Meets or exceeds OEM specifications
- New OEM riveted pin retaining design
Encore Automotive – Engine Valve Lifter (Part No.VL-D20004)
from
$20.99
Encore Automotive Valve Lifter is a steel cylinder designed to maintain zero valve clearance in a combustion engine.
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- Precisely tapered and machined to fit the specific application
- Designed to conserve energy by reducing heat escape
- Designed to conserve energy by reducing heat escapeáá
Carquest Premium – Crankshaft Sensor (Part No.CSC1052)
from
$79.99
A leader in vehicle electronic solutions, each premium product meets or exceeds OE specifications in appearance, fit, and function, ensuring easy installation and excellent performance. The product has been tested under extreme environments.
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Product Features:
- Reliable circuit board and product structure design, 3D proofing, and field test verification to ensure correct signal output at all speeds.
- Manufactured in an anti-static environment to ensure reliability and stability.
- Extreme temperature and salt spray tests simulate real-world vehicle conditions to ensure durability and reliability.
- Providing this premium product line, we meet the service professionals needs with the highest quality product every time the part comes out of the box.
GM Genuine Parts – Engine Crankshaft Position Sensor (Part No.12669636)
from
$39.99
ACDelco GM Original Equipment Engine Crankshaft Position Sensors monitor the position and rotational speed of the crankshaft, and are GM-recommended replacements for your vehicle’s original components. The signal from the crankshaft position sensor is used by the engine control module to determine fuel injection and ignition timing. These original equipment engine crankshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
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- This part requires programming and/or special setup procedures. GM Service Information describes the procedures and special tools needed to ensure proper operation in the vehicle
- Helps keep engine timing and fuel injection running in sync
- Helps provide proper alignment, positioning, and spacing for easy installation
- Synchronizes engine valves and pistons for excellent engine performance
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Carquest Premium – Engine Crankshaft Position Sensor (Part No.CSA1502)
from
$99.99
Carquest Premium crankshaft position sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium crankshaft and camshaft sensors are engineered with technology that provides increased output accuracy through a stronger, more consistent signal. Our sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium crankshaft and camshaft position sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.
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- Engineered with technology that provides increased accuracy with a stronger, more consistent signal
- Sensors are based on proven hall effect and variable reluctance technology
- Includes OE-style brackets, hold downs, hardware, or spacers as needed for each application.
- O-rings and seals are included if required.
- Weather-tight connectors prevent leaks and corrosion for better reliability.
- Extensive design validation testing and 100% end-of-line tested.
- Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
Upgrade your 2021 GMC Sierra 2500 HD with Top-Quality Engine Parts
When it comes to maintaining or upgrading your 2021 GMC Sierra 2500 HD, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Engine Parts are key to keeping your Sierra 2500 HD functioning at its best. At Advance Auto Parts, we offer a wide selection of 39 Engine Parts for the 2021 GMC Sierra 2500 HD, designed to meet your needs without breaking the bank.
From
Valve Cover and Cylinder Head
replacements to
Engine Gaskets and Seals
upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.
Affordable Prices and Wide Selection
Shopping for Engine Parts for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Engine Parts for your 2021 GMC Sierra 2500 HD at great prices.
Our Engine Parts inventory for this model
ranges from just $0.99 to $9,646.00, with
an average price of $827.75.
Our 39 Engine Parts in stock come from 14 trusted brands, so you’re sure to find the right part for your 2021 GMC Sierra 2500 HD without overspending.
Explore Related Parts and More
While you’re here, don’t forget to check out other essential categories that go hand in hand with Engine Part upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants
and more to make sure your 2021 GMC Sierra 2500 HD is always ready to roll. We’re committed to providing you with everything you need to keep your Sierra 2500 HD in top shape, all in one place.
Start shopping confidently below for your 2021 GMC Sierra 2500 HD!
Best-Selling Valve Cover and Cylinder Heads for 2021 GMC Sierra 2500 HDs
Enhance the driving experience in your GMC with 4 quality Valve Cover and Cylinder Head components, starting at $11.79.
GM Genuine Parts – Gen III/IV Lifter Guide (Part No.12595365)
from
$14.99
GM Genuine Parts Engine Valve Lifter Guide are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Felpro – Engine Cylinder Head Bolt Set (Part No.ES 73121)
from
$56.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Avoid risk associated with re-use of T-T-Y (torque to yield) head bolts
- Validated for fit, form and function
- Unsurpassed quality you can trust
Spartan – GM 6.6 OHV L8T Head (Part No.2CT31)
from
$427.99
GM 6.6 OHV L8T Head
Melling Select Performance – Valve Train Set Up Spring (Part No.VTSS100)
from
$11.79
Melling Performance valvetrain checking springs feature a low-tension design that allows them to be installed by hand for measuring piston-to-valve clearance, rocker arm ratio, and degreeing in a camshaft.
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Most Popular 2021 GMC Sierra 2500 HD Engine Gaskets and Seals
Customize your GMC with 5 Engine Gaskets and Seals products
like Valve Cover Gaskets,
Oil Pan Gaskets, and
Fuel Pump Gaskets, all
priced under $26.99.
Felpro – Engine Valve Cover Gasket Set (Part No.VS 50907 R)
from
$26.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- DESIGNED FOR IMPERFECT SEALING SURFACES – Engineered and manufactured specifically for the repair environment to help seal imperfect sealing surfaces
- SUPERIOR SEAL – Manufactured with rubber compounds to help ensure a consistent and long-life seal
- PRECISE DESIGN – Engineered to work with the embossed cover and pan flanges
- PREVENTS OVERTIGHTENING – Features compression limiters incorporated into the design to help eliminate overtightening (application specific)
- OE-STYLE REPLACEMENT GASKET – Engineered for OE-style molded rubber gasket replacement
- EVERY PART FOR THE REPAIR – Fel-Pro gasket sets include every part needed for the repair unless otherwise noted
Victor Reinz – REINZOSIL RTV Silicone (Part No.70-31414-10)
from
$8.49
Victor Reinz Reinzosil is a permanently elastic, universal silicone sealing compound that is resistant to extreme temperatures, mineral oils, numerous synthetic oils, lubricants, gasoline, diesel/biodiesel fuels, greases, hot and cold water, detergents, sunlight, ozone, and salt water. Its durability, flexibility, and versatility make it a favourite among import car repair specialists. Reinzosil is the RTV sealant of choice in Europe; now, Victor Reinz brings this exceptional, in-demand product to the North American aftermarket. Reinzosil is so versatile that it can replace a dozen or more other varieties of RTV, eliminating excessive SKUs and saving valuable inventory space., Victor Reinz Reinzosil is a permanently elastic, universal silicone sealing compound that is resistant to extreme temperatures, mineral oils, numerous synthetic oils, lubricants, gasoline, diesel/biodiesel fuels, greases, hot and cold water, detergents, sunlight, ozone, and salt water. Its durability, flexibility, and versatility make it a favourite among import car repair specialists. Reinzosil is the RTV sealant of choice in Europe; now, Victor Reinz brings this exceptional, in-demand product to the North American aftermarket. Reinzosil is so versatile that it can replace a dozen or more other varieties of RTV, eliminating excessive SKUs and saving valuable inventory space.
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Product Features:
- Resistant to temperatures from -58 Deg F to 608 Deg F (-50 Deg C to 320 Deg C)
- Insignificant shrinkage and loss of mass even in high-heat environments.
- Fast-curing, low-odor, noncorrosive (pH neutral, non-acidic, non-oxidizing), and will not harm oxygen sensors
- Sealing gap 0.006 in (0.15 mm)
GM Genuine Parts – Oil Pan Gasket (Part No.12666993)
from
$7.99
GM Genuine Parts Engine Oil Pan Gaskets are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
Product Features:
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Product Features:
- Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
- GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
- GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
- GM regularly updates production and service part designs to integrate new materials and technologies
Felpro – Fuel Pump Mounting Gasket (Part No.73158)
from
$5.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered for the sealing repair environment
- Unsurpassed quality you can trust
- Validated for fit, form, and function
Felpro – Engine Oil Dipstick Tube O-Ring (Part No.73889)
from
$0.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered for the sealing repair environment
- Validated for fit, form and function
- Unsurpassed quality you can trust
Top Picks for 2021 GMC Sierra 2500 HD Engine Mounts
Upgrade GMC Sierra 2500 HDs with top-quality Engine Mounts parts, including 2 OEM and aftermarket selections for your 2021 model.
Anchor – Engine Mount (Part No.3587)
from
$79.99
Product Features:
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- This mount supports the engine and dampens vibration.
- Natural and SBR rubber provide maximum life and performance.
- Steel fasteners are heat treated grade 5 bolts.
- A special bonding agent is used to ensure a rubber to metal bond.
- Rubber material is mixed to specific Durometer, hardness.
- Limited Warranty.
- All mounts are specifically engineered and designed to OE standards using the latest CAD/CAM engineering process ensuring the highest consistency and quality.
- Only natural and Styrene Butadiene rubber is used to provide premium abrasion resistance and aging stability to ensure maximum life and performance.
- Any included fasteners are hardened steel with heat treated Grade No. 5 bolts.
- Chemlock bonding agent is used to ensure a superior rubber-to-metal bond.
- All Rubber material is manufactured to specific Durometer (hardness) measurements based on vehicle application requirements.
- Hydraulic Mounts, applicable where OE, are specifically engineered for high vibration and torque applications and are filled with special hydraulic fluid to dampen excess noise and vibration.
Anchor – Engine Mount (Part No.3588)
from
$68.99
Product Features:
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- This mount supports the engine and dampens vibration.
- Natural and SBR rubber provide maximum life and performance.
- Steel fasteners are heat treated grade 5 bolts.
- A special bonding agent is used to ensure a rubber to metal bond.
- Rubber material is mixed to specific Durometer, hardness.
- Limited Warranty.
- All mounts are specifically engineered and designed to OE standards using the latest CAD/CAM engineering process ensuring the highest consistency and quality.
- Only natural and Styrene Butadiene rubber is used to provide premium abrasion resistance and aging stability to ensure maximum life and performance.
- Any included fasteners are hardened steel with heat treated Grade No. 5 bolts.
- Chemlock bonding agent is used to ensure a superior rubber-to-metal bond.
- All Rubber material is manufactured to specific Durometer (hardness) measurements based on vehicle application requirements.
- Hydraulic Mounts, applicable where OE, are specifically engineered for high vibration and torque applications and are filled with special hydraulic fluid to dampen excess noise and vibration.
In-Demand Camshafts for 2021 GMC Sierra 2500 HDs
Select from 6 premium Camshafts parts for your 2021 GMC Sierra 2500 HD, with prices ranging from $22.49 to $42.99.
Sealed Power – Engine Valve Lifter (Part No.HT-2148A)
from
$24.99
Sealed Power® Vintage components provide coverage for applications over 35 years old, restoring classics with like new performance. Leading edge materials, ISO & QS certified manufacturing ensures performance and longevity for treasured engine rebuilds.
Product Features:
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Product Features:
- Unsurpassed quality that you can trust
- Uses leading edge materials
- State-of-the-art manufacturing
- Exacting tolerances
- Meets or exceeds OEM specifications
- New OEM riveted pin retaining design
GM Genuine Parts – Engine Camshaft Position Sensor (Part No.12636947)
from
$42.99
ACDelco GM Original Equipment Engine Camshaft Position Sensors monitor the rotational position of the camshaft(s), and are GM-recommended replacements for your vehicle’s original components. They provide a signal to the engine control module which compares the camshaft position with the crankshaft position to determine ignition and fuel injection timing. These original equipment engine camshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
Product Features:
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Product Features:
- Helps keep engine timing and fuel injection running in sync
- Helps provide proper alignment, positioning, and spacing for easy installation
- Synchronizes engine valves and pistons for excellent engine performance
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
GM Genuine Parts – Engine Camshaft Position Sensor (Part No.12623093)
from
$26.99
ACDelco GM Original Equipment Engine Camshaft Position Sensors monitor the rotational position of the camshaft(s), and are GM-recommended replacements for your vehicle’s original components. They provide a signal to the engine control module which compares the camshaft position with the crankshaft position to determine ignition and fuel injection timing. These original equipment engine camshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
Product Features:
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Product Features:
- Helps keep engine timing and fuel injection running in sync
- Helps provide proper alignment, positioning, and spacing for easy installation
- Synchronizes engine valves and pistons for excellent engine performance
- GM-recommended replacement part for your GM vehicle’s original factory component
- Offering the quality, reliability, and durability of GM OE
- Manufactured to GM OE specification for fit, form, and function
Felpro – Engine Camshaft Thrust Plate (Part No.ES 73115)
from
$42.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered for the sealing repair environment
- Validated for fit, form and function
- Unsurpassed quality you can trust
Carquest Premium – Engine Camshaft Position Sensor (Part No.CSA4435)
from
$39.99
Carquest Premium camshaft position sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium crankshaft and camshaft sensors are engineered with technology that provides increased output accuracy through a stronger, more consistent signal. Our sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium crankshaft and camshaft position sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.
Product Features:
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Product Features:
- Engineered with technology that provides increased accuracy with a stronger, more consistent signal
- Sensors are based on proven hall effect and variable reluctance technology
- Includes OE-style brackets, hold downs, hardware, or spacers as needed for each application.
- O-rings and seals are included if required.
- Weather-tight connectors prevent leaks and corrosion for better reliability.
- Extensive design validation testing and 100% end-of-line tested.
- Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
Dorman – Magnetic Camshaft Position Sensor (Part No.962-277)
from
$22.49
This engine camshaft position sensor is designed to match the fit and function of an original sensor to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.
Product Features:
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Product Features:
- Direct replacement – this engine camshaft position sensor is designed to match the fit and function of an original sensor on specified vehicles
- Ideal solution – engineered to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage
- Durable construction – designed and manufactured to strict specifications for reliable performance
- Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
Most Sold 2021 GMC Sierra 2500 HD Engine Timing Parts
Explore our best-selling GMC parts for the 2021 Sierra 2500 HD among 3 OEM and aftermarket options starting from $44.49.
Cloyes Gear – Engine Timing Chain (Part No.9-4205)
from
$44.49
Since 1921, Cloyes has been the trusted leader in automotive timing systems. Our timing chains are built to synchronize crankshaft and camshaft rotation with absolute accuracy, ensuring precise valve timing and long-term engine performance. Available as stand-alone chains or in complete kits, Cloyes timing chains are manufactured from premium materials, heat-treated, pre-stressed and engineered for a perfect chain-to-sprocket tooth fit ¿ delivering quiet operation, durability, and OE-level performance you can count on. To ensure total timing system integrity, Cloyes recommends replacing the chain along with the tensioners, guides, and sprockets during service. Trusted by professionals for over a century & backed by an industry-leading warranty and technical support.
Product Features:
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Product Features:
- Pre-stressed and heat-treated steel construction for increased strength, and wear resistance, delivering long-term durability even in high-stress environments.
- Cloyes chains are engineered and manufactured with precision pitch control to ensure optimal chain-to-sprocket fit reducing noise, minimizing fatigue, and maintaining accurate timing.
- Designed in the USA and manufactured using premium materials for OE-level fit and function, allowing for smooth installation and reliable performance.
- Each part is extensively tested for function, fitment, and durability to ensure consistent quality and optimal performance, reducing the risk of comebacks.
- Available in application-specific kit or as a stand-alone chain, offering installation flexibility and convenience.
- .
Cloyes Performance – High Performance Timing Set (Part No.9-3678X5)
from
$139.99
Cloyes Performance Tensioner Elimination GM LT Engine Timing Set eliminates the factory tensioner while maintaining tunable accurate timing for VVT-equipped LT engines. By removing the factory tensioner, this kit eliminates chain slack and potential failure. The combination of Cloyes TRUE¿ Roller chain, and precision-machined sprockets ensures a center distance corrected timing drive for reliable performance on VVT-equipped LT engines.
Product Features:
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Product Features:
- Billet 5-keyway crank sprocket for ±4° adjustability with 2 custom diamond-impregnated friction washers for front and thrust hubs. Precision oil pump spline drive for durable, reliable oil pressure delivery.
- Billet 5-keyway crank sprocket for ▒4░ adjustability with 2 custom diamond-impregnated friction washers for front and thrust hubs. Precision oil pump spline drive for durable, reliable oil pressure delivery.
- Premium Cloyes TRUE¿ roller chain (0.250¿) for reduced friction and smooth operation.
- Premium Cloyes TRUE┐ roller chain (0.250┐) for reduced friction and smooth operation.
- Tensioner elimination guide provided to simplify installation and ensure proper lubrication and chain stability.
- Center distance corrected to eliminate chain slack for accurate tunable VVT phaser operation.
- Made in Paris, Arkansas, USA: all machined billet parts proudly manufactured in the USA.
Cloyes Gear – Engine Timing Crankshaft Sprocket (Part No.S1111)
from
$80.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems. As a critical component of the engine’s timing system, the crankshaft sprockets work in unison with the timing chain, tensioners, guides and other sprockets, to ensure precise timing. Cloyes engine timing crankshaft sprockets are precision-tooled with exact tooth geometry and a perfectly matched bore, off-set and timing index for superior fit, reliability, and long-term performance. To ensure total timing system integrity, Cloyes recommends replacing the chain along with the tensioners, guides, and sprockets during service. Trusted by professionals for over a century & backed by an industry-leading limited Warranty and technical support.
Product Features:
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Product Features:
- Features precision-tooled tooth form, bore, off-set and timing index for superior fit, reliability, and long-term performance in engine timing repairs
- CAD designed and manufactured using premium materials and heat-treated for OE-level fit and function, allowing for smooth installation and reliable performance
- Each part is extensively tested for function, fitment, and durability to ensure consistent quality and optimal performance, reducing the risk of comebacks
- Available in application-specific kit or as a stand-alone product, offering installation flexibility and convenience
FAQs for 2021 GMC Sierra 2500 HD Engine Parts
Which Engine Parts are best-sellers for 2021 GMC Sierra 2500 HDs?
Out of 39 Engine Parts that fit 2021 GMC Sierra 2500 HDs, the following parts are the top sellers:
- Engine Valve Lifter (12486346) – $24.99
- Gen III/IV Lifter Guide (11949076) – $14.99
- Engine Timing Chain (12152365) – $44.49
What’s the price range for 2021 GMC Sierra 2500 HD Engine Parts?
Engine Part prices for the 2021 GMC Sierra 2500 HD start at $0.99 and go up to $9,646.00 for the most premium parts.
What’s the average price of a Engine Part for a 2021 GMC Sierra 2500 HD?
The average price for Engine Parts for the 2021 GMC Sierra 2500 HD is $827.75. Keep in mind the variety of part types within our Engine Part category so you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Engine Parts for other GMC Sierra 2500 HD model years?
What are the cheapest Engine Parts for my 2021 GMC Sierra 2500 HD?
The cheapest 2021 GMC Sierra 2500 HD Engine Parts we carry in stock are:
- Engine Oil Dipstick Tube O-Ring (50251306) – $0.99
- Fuel Pump Mounting Gasket (50251311) – $5.99
- Oil Pan Gasket (12515458) – $7.99
- Engine Oil Cooler Gasket (50233897) – $8.39
- REINZOSIL RTV Silicone (12588189) – $8.49
What types of Engine Parts do you sell for my 2021 GMC Sierra 2500 HD?
As of 6/2/26, these are some of the most in-demand types of Engine Parts for a 2021 GMC Sierra 2500 HD:
Can I get help with 2021 GMC Sierra 2500 HD Engine Part orders?
Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Engine Parts and more.
What is your return policy for GMC Sierra 2500 HD Engine Parts?
Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Engine Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.
