2021 GMC Sierra 2500 HD Engine Parts

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Essential Engine Parts for 2021 GMC Sierra 2500 HDs

Felpro – Felpro Engine Oil Dipstick Tube O-Ring, 73889 (Part No.73889)

Felpro Engine Oil Dipstick Tube O-Ring, 73889

from

$0.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Anchor – Anchor Engine Mount, 3588 (Part No.3588)

Anchor Engine Mount, 3588

from

$68.99
Anchor Engine Mount, 3588. DRIVELINE PARTS AND MOUNTS>MOUNTS>ENGINE MOUNTS>ENGINE MOUNTS from Anchor
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NTK – NTK Engine Camshaft Position Sensor, EC0099 (Part No.EC0099)

NTK Engine Camshaft Position Sensor, EC0099

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$65.99
The Camshaft Position Sensor plays a vital role in your engine’s operation, to determine the exact position and speed of the camshaft(s) to the ECM. The ECM uses this information to determine fuel and spark timing as well as VVT operation. A failed sensor can result in a check engine light, hard starting or failure to start, increased vehicle emissions and engine misfire. Camshaft Position Sensors are a premium quality product with outstanding support and leading innovation bred from our OE heritage.
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Carquest Premium – Carquest New Map Sensor, ECC1082 (Part No.ECC1082)

Carquest New Map Sensor, ECC1082

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$111.99
CARQUEST MAP sensors are manufactured with critical OEM components to ensure that your engine runs efficiently to reach the best gas mileage on your vehicle.
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ACDelco – ACDelco Air Pressure Sensor, 12711681 (Part No.12711681)

ACDelco Air Pressure Sensor, 12711681

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$76.99
ACDelco GM Original Equipment Multi Purpose Sensors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.
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ARP Auto Racing – ARP Auto Racing ARP Harmonic Damper Bolt Kit, 234-2503 (Part No.234-2503)

ARP Auto Racing ARP Harmonic Damper Bolt Kit, 234-2503

from

$53.99
As the crankshaft flexes and twists, the balancer absorbs incredible amounts of kinetic energy. To ensure that the balancer is locked in place, ARP has developed these ultra-strong 200,000 psi bolts that let you exert maximum clamping force. Special features include 1/4′ thick, wide area washer and an extra tall 12-point head that accepts a deep socket and eliminates the worry of stripping the head.
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Cloyes Gear – Cloyes Gear Engine Timing Crankshaft Sprocket, S1111 (Part No.S1111)

Cloyes Gear Engine Timing Crankshaft Sprocket, S1111

from

$80.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems. As a critical component of the engine’s timing system, the crankshaft sprockets work in unison with the timing chain, tensioners, guides and other sprockets, to ensure precise timing. Cloyes engine timing crankshaft sprockets are precision-tooled with exact tooth geometry and a perfectly matched bore, off-set and timing index for superior fit, reliability, and long-term performance. To ensure total timing system integrity, Cloyes recommends replacing the chain along with the tensioners, guides, and sprockets during service. Trusted by professionals for over a century & backed by an industry-leading Warranty (limited) and technical support. 
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Victor Reinz – Victor Reinz Engine Oil Cooler Gasket, 71-13509-00 (Part No.71-13509-00)

Victor Reinz Engine Oil Cooler Gasket, 71-13509-00

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$8.29
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.
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Cloyes Gear – Cloyes Gear Engine Timing Components, Camshaft Timing Kit, Crankshaft Timing Kit, Timing Set with Sprockets, Timing Drive Assembly, C-3222 (Part No.C-3222)

Cloyes Gear Engine Timing Components, Camshaft Timing Kit, Crankshaft Timing Kit, Timing Set with Sprockets, Timing Drive Assembly, C-3222

from

$68.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems delivering premium-quality solutions. Cloyes engine timing sets are engineered for precision, durability, and optimal engine performance. Sets includes crankshaft sprocket, camshaft sprocket and chain. To ensure total timing system integrity, Cloyes recommends replacing all engine timing components. Trusted by professionals for over a century & backed by an industry-leading warranty and technical support.
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K&N – K&N Oil Catch Can, 81-0812 (Part No.81-0812)

K&N Oil Catch Can, 81-0812

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$157.99
The K&N Air Oil Separator protects the engine and intake tract from blowby by capturing the oil in our industry leading high capacity reservoir. This helps prevent power loss and possible engine damage caused by blowby. The K&N Air Oil Separator is quick and easy to install in about 30 minutes with basic tools and uses factory-style hose connections to quickly snap on and off. The oil separator replaces the factory line from the crank case allowing the oil separator to be mounted to a coinvent location in your engine bay. No tools are needed to check and empty the oil collector reservoir. Each unit is engineered specifically for your vehicle and is backed by our No-Hassle Limited Warranty.
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Felpro – Felpro Engine Crankshaft Seal Kit, TCS 46193 (Part No.TCS 46193)

Felpro Engine Crankshaft Seal Kit, TCS 46193

from

$42.99
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Felpro – Felpro Engine Cylinder Head Bolt Set, ES 73121 (Part No.ES 73121)

Felpro Engine Cylinder Head Bolt Set, ES 73121

from

$57.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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INA US – INA US Engine Timing Chain Kit, ZC-9-4205SB (Part No.ZC-9-4205SB)

INA US Engine Timing Chain Kit, ZC-9-4205SB

from

$132.99
INA timing chain kits include all essential components to ensure that the repair is done right the first time. Each kit contains all necessary chains, tensioners, and guides. In certain applications the kit also contains the necessary gears and sprockets, along with a specially formulated, high performance, chain additive uniquely made for Schaeffler by Liqui Moly. The chain additive helps reduce friction during the break in period and reduces run-in wear by up to twenty percent.
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Cloyes Gear – Cloyes Gear Engine Timing Chain, 9-4194 (Part No.9-4194)

Cloyes Gear Engine Timing Chain, 9-4194

from

$43.99
Pre-Stressed And Heat-Treated For Increased Durability. Precision Cut Plates And Rollers With Smooth Finish. Precision Pitch Control For Proper Chain To Sprocket Tooth Fit.
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Melling Select Performance – Melling Select Performance Valve Train Set Up Spring, VTSS100 (Part No.VTSS100)

Melling Select Performance Valve Train Set Up Spring, VTSS100

from

$11.79
Melling Performance valvetrain checking springs feature a low-tension design that allows them to be installed by hand for measuring piston-to-valve clearance, rocker arm ratio, and degreeing in a camshaft.
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Felpro – Felpro Engine Camshaft Thrust Plate, ES 73115 (Part No.ES 73115)

Felpro Engine Camshaft Thrust Plate, ES 73115

from

$43.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
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Carquest Premium – Carquest Engine Oil Filler Cap: Twist-Lock, Direct Fit, Provides Tight Seal, 1 Pack, 10099 (Part No.10099)

Carquest Engine Oil Filler Cap: Twist-Lock, Direct Fit, Provides Tight Seal, 1 Pack, 10099

from

$11.99
Manufactured from high quality components by an OE Supplier. Proper fit and sealing prevents oil loss. Designed to OEM specifications. High quality finish is designed to compliment the engine compartment appearance.
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aFe POWER – "aFe POWER BladeRunner 3"" Aluminum Hot Charge Pipe, Black, 46-20448-B" (Part No.46-20448-B)

"aFe POWER BladeRunner 3"" Aluminum Hot Charge Pipe, Black, 46-20448-B"

from

$415.99
Smooth transitions in the mandrel-bent aluminum pipes decrease turbulence and minimize pressure loss, increasing horsepower and torque. This kit includes high-quality, stainless-steel, spring-loaded T-bolt clamps and heavy-duty, 5-ply, polyester reinforced silicone couplings for superior strength and durability. Finished in wrinkle black powder coating with a unique laser-etched aFe POWER logo for a custom look.
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Rotomaster – Rotomaster Turbocharger Oil Line, A1372229N (Part No.A1372229N)

Rotomaster Turbocharger Oil Line, A1372229N

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$108.99
The Rotomaster Turbocharger Oil Lines supports proper turbocharger lubrication by maintaining consistent oil flow to and from the turbocharger. Built for high-heat environments, it helps protect turbo bearings and seals while reducing the risk of oil-related failures.
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Felpro – Felpro Fuel Pump Mounting Gasket, 73158 (Part No.73158)

Felpro Fuel Pump Mounting Gasket, 73158

from

$5.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Encore Automotive – Encore Automotive Engine Valve Lifter, VL-D20004 (Part No.VL-D20004)

Encore Automotive Engine Valve Lifter, VL-D20004

from

$20.99
Encore Automotive Valve Lifter is a steel cylinder designed to maintain zero valve clearance in a combustion engine.
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Dorman – Dorman Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces, 904-380 (Part No.904-380)

Dorman Silicone Valve Cover Gasket Set: Exact Fit, 2 Pieces, 904-380

from

$101.99
This valve cover gasket is designed to match the fit, function and performance of an original equipment gasket on specified vehicles. Made of durable materials, it is engineered to help ensure a long-lasting seal under extreme underhood conditions.
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Dorman – Dorman Turbocharger Coolant Return Line, 667-167 (Part No.667-167)

Dorman Turbocharger Coolant Return Line, 667-167

from

$22.29
This turbocharger coolant line is designed to match the fit and function of the original line on specified vehicles. Made of quality materials, it is engineered for reliable performance and durability.
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GM Genuine Parts – GM Genuine Parts Oil Pan Seal, 12621086 (Part No.12621086)

GM Genuine Parts Oil Pan Seal, 12621086

from

$15.49
GM Genuine Parts Engine Oil Pan Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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GM Genuine Parts – GM Genuine Parts Non-hydraulic Eng Timing Damper Kit: Exact Fit, W/ Tensioner, Bolts, & Retainers, 12626407 (Part No.12626407)

GM Genuine Parts Non-hydraulic Eng Timing Damper Kit: Exact Fit, W/ Tensioner, Bolts, & Retainers, 12626407

from

$52.99
ACDelco GM Original Equipment Engine Timing Damper Kits remove unnecessary slack from the timing chain to help prevent chain rattle and excessive component wear, and are GM-recommended replacements for your vehicle’s original components. These original equipment engine timing damper kits contain components that will provide the same performance, durability, and service life you expect from General Motors.
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GM Genuine Parts – GM Genuine Parts Oil Pan Cover Gasket: Nitrile Coated SS, 12611384 (Part No.12611384)

GM Genuine Parts Oil Pan Cover Gasket: Nitrile Coated SS, 12611384

from

$9.99
GM Genuine Parts Engine Oil Pan Cover Gasket are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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Carquest Premium – Carquest Engine Crankshaft Position Sensor, CSA1439 (Part No.CSA1439)

Carquest Engine Crankshaft Position Sensor, CSA1439

from

$109.99
Carquest Premium crankshaft position sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium crankshaft and camshaft sensors are engineered with technology that provides increased output accuracy through a stronger, more consistent signal. Our sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium crankshaft and camshaft position sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.
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Carquest Premium – Carquest Engine Oil Level Sensor, SBC3719 (Part No.SBC3719)

Carquest Engine Oil Level Sensor, SBC3719

from

$49.99
The engine lubrication system is critical to engine operation and long life. On some vehicle applications, the engine control module monitors the engine oil level to ensure lubrication is not lost.
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Upgrade your 2021 GMC Sierra 2500 HD with Top-Quality Engine Parts

When it comes to maintaining or upgrading your 2021 GMC Sierra 2500 HD, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Engine Parts are key to keeping your Sierra 2500 HD functioning at its best. At Advance Auto Parts, we offer a wide selection of 47 Engine Parts for the 2021 GMC Sierra 2500 HD, designed to meet your needs without breaking the bank. From Valve Cover and Cylinder Head replacements to Engine Gaskets and Seals upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Engine Parts for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Engine Parts for your 2021 GMC Sierra 2500 HD at great prices. Our Engine Parts inventory for this model ranges from just $0.99 to $689.99, with an average price of $70.97. Our 47 Engine Parts in stock come from 13 trusted brands, so you’re sure to find the right part for your 2021 GMC Sierra 2500 HD without overspending.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Engine Part upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 GMC Sierra 2500 HD is always ready to roll. We’re committed to providing you with everything you need to keep your Sierra 2500 HD in top shape, all in one place. Start shopping confidently below for your 2021 GMC Sierra 2500 HD!

Best-Selling Valve Cover and Cylinder Heads for 2021 GMC Sierra 2500 HDs

Enhance the driving experience in your GMC with 5 quality Valve Cover and Cylinder Head components, starting at $11.79.

Sealed Power – Sealed Power Engine Valve Lifter, HT-2148A (Part No.HT-2148A)

Sealed Power Engine Valve Lifter, HT-2148A

from

$28.49
Sealed Power® Vintage components provide coverage for applications over 35 years old, restoring classics with like new performance. Leading edge materials, ISO & QS certified manufacturing ensures performance and longevity for treasured engine rebuilds.
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GM Genuine Parts – GM Genuine Parts Gen III/IV Lifter Guide, 12595365 (Part No.12595365)

GM Genuine Parts Gen III/IV Lifter Guide, 12595365

from

$15.79
GM Genuine Parts Engine Valve Lifter Guide are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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Felpro – Felpro Engine Cylinder Head Bolt Set, ES 73121 (Part No.ES 73121)

Felpro Engine Cylinder Head Bolt Set, ES 73121

from

$57.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Felpro – Felpro Engine Cylinder Head Bolt Set, ES 73121-1 (Part No.ES 73121-1)

Felpro Engine Cylinder Head Bolt Set, ES 73121-1

from

$57.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
See More

Melling Select Performance – Melling Select Performance Valve Train Set Up Spring, VTSS100 (Part No.VTSS100)

Melling Select Performance Valve Train Set Up Spring, VTSS100

from

$11.79
Melling Performance valvetrain checking springs feature a low-tension design that allows them to be installed by hand for measuring piston-to-valve clearance, rocker arm ratio, and degreeing in a camshaft.
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Most Popular 2021 GMC Sierra 2500 HD Engine Gaskets and Seals

Customize your GMC with 5 Engine Gaskets and Seals products like Valve Cover Gaskets, Oil Pan Gaskets, and Fuel Pump Gaskets, all priced under $42.99.

Felpro – Felpro Engine Valve Cover Gasket Set, VS 50907 R (Part No.VS 50907 R)

Felpro Engine Valve Cover Gasket Set, VS 50907 R

from

$26.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
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Victor Reinz – Victor Reinz Engine Oil Pan Gasket Set, 10-10318-01 (Part No.10-10318-01)

Victor Reinz Engine Oil Pan Gasket Set, 10-10318-01

from

$42.99
Built to meet or exceed the standards of original equipment manufacturers around the world and avoid comebacks Victor Reinz oil pan gaskets deliver the seal that prevents drops on the driveway. Victor Reinz engineers select the best designs and materials for the specific application. The level of sophistication in oil pan gasket form and function has jumped greatly in recent years, with the gasket often being an integral part of the manufacturers efforts to control engine noise, vibration, and harshness (NVH). Only a company with innovative gasket technology can supply the right gasket for every application, new or old.
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Victor Reinz – Victor Reinz REINZOSIL RTV Silicone, 70-31414-10 (Part No.70-31414-10)

Victor Reinz REINZOSIL RTV Silicone, 70-31414-10

from

$8.49
Victor Reinz Reinzosil is a permanently elastic, universal silicone sealing compound that is resistant to extreme temperatures, mineral oils, numerous synthetic oils, lubricants, gasoline, diesel/biodiesel fuels, greases, hot and cold water, detergents, sunlight, ozone, and salt water. Its durability, flexibility, and versatility make it a favourite among import car repair specialists. Reinzosil is the RTV sealant of choice in Europe; now, Victor Reinz brings this exceptional, in-demand product to the North American aftermarket. Reinzosil is so versatile that it can replace a dozen or more other varieties of RTV, eliminating excessive SKUs and saving valuable inventory space., Victor Reinz Reinzosil is a permanently elastic, universal silicone sealing compound that is resistant to extreme temperatures, mineral oils, numerous synthetic oils, lubricants, gasoline, diesel/biodiesel fuels, greases, hot and cold water, detergents, sunlight, ozone, and salt water. Its durability, flexibility, and versatility make it a favourite among import car repair specialists. Reinzosil is the RTV sealant of choice in Europe; now, Victor Reinz brings this exceptional, in-demand product to the North American aftermarket. Reinzosil is so versatile that it can replace a dozen or more other varieties of RTV, eliminating excessive SKUs and saving valuable inventory space.
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GM Genuine Parts – GM Genuine Parts Oil Pan Gasket, 12666993 (Part No.12666993)

GM Genuine Parts Oil Pan Gasket, 12666993

from

$7.99
GM Genuine Parts Engine Oil Pan Gaskets are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).
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Felpro – Felpro Fuel Pump Mounting Gasket, 73158 (Part No.73158)

Felpro Fuel Pump Mounting Gasket, 73158

from

$5.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
See More

Top Picks for 2021 GMC Sierra 2500 HD Engine Mounts

Upgrade GMC Sierra 2500 HDs with top-quality Engine Mounts parts, including 2 OEM and aftermarket selections for your 2021 model.

Anchor – Anchor Engine Mount, 3587 (Part No.3587)

Anchor Engine Mount, 3587

from

$79.99
Anchor Engine Mount, 3587. DRIVELINE PARTS AND MOUNTS>MOUNTS>ENGINE MOUNTS>ENGINE MOUNTS from Anchor
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Anchor – Anchor Engine Mount, 3588 (Part No.3588)

Anchor Engine Mount, 3588

from

$68.99
Anchor Engine Mount, 3588. DRIVELINE PARTS AND MOUNTS>MOUNTS>ENGINE MOUNTS>ENGINE MOUNTS from Anchor
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In-Demand Camshafts for 2021 GMC Sierra 2500 HDs

Select from 5 premium Camshafts parts for your 2021 GMC Sierra 2500 HD, with prices ranging from $25.99 to $43.99.

GM Genuine Parts – GM Genuine Parts Engine Camshaft Position Sensor, 12636947 (Part No.12636947)

GM Genuine Parts Engine Camshaft Position Sensor, 12636947

from

$42.99
ACDelco GM Original Equipment Engine Camshaft Position Sensors monitor the rotational position of the camshaft(s), and are GM-recommended replacements for your vehicle’s original components. They provide a signal to the engine control module which compares the camshaft position with the crankshaft position to determine ignition and fuel injection timing. These original equipment engine camshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
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GM Genuine Parts – GM Genuine Parts Engine Camshaft Position Sensor, 12623093 (Part No.12623093)

GM Genuine Parts Engine Camshaft Position Sensor, 12623093

from

$26.99
ACDelco GM Original Equipment Engine Camshaft Position Sensors monitor the rotational position of the camshaft(s), and are GM-recommended replacements for your vehicle’s original components. They provide a signal to the engine control module which compares the camshaft position with the crankshaft position to determine ignition and fuel injection timing. These original equipment engine camshaft position sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
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Felpro – Felpro Engine Camshaft Thrust Plate, ES 73115 (Part No.ES 73115)

Felpro Engine Camshaft Thrust Plate, ES 73115

from

$43.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
See More

Carquest Premium – Carquest Engine Camshaft Position Sensor, CSA4435 (Part No.CSA4435)

Carquest Engine Camshaft Position Sensor, CSA4435

from

$38.49
Carquest Premium camshaft position sensors are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium crankshaft and camshaft sensors are engineered with technology that provides increased output accuracy through a stronger, more consistent signal. Our sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Carquest Premium crankshaft and camshaft position sensors undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.
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Dorman – Dorman Magnetic Camshaft Position Sensor, 962-277 (Part No.962-277)

Dorman Magnetic Camshaft Position Sensor, 962-277

from

$25.99
This engine camshaft position sensor is designed to match the fit and function of an original sensor to help ensure the engine control unit receives proper inputs when an original sensor has failed from heat or internal component damage.
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Most Sold 2021 GMC Sierra 2500 HD Engine Timing Parts

Explore our best-selling GMC parts for the 2021 Sierra 2500 HD among 8 OEM and aftermarket options starting from $31.99.

Cloyes Gear – Cloyes Gear Engine Timing Chain, 9-4205 (Part No.9-4205)

Cloyes Gear Engine Timing Chain, 9-4205

from

$45.49
Since 1921, Cloyes has been the trusted leader in automotive timing systems. Our timing chains are built to synchronize crankshaft and camshaft rotation with absolute accuracy, ensuring precise valve timing and long-term engine performance. Available as stand-alone chains or in complete kits, Cloyes timing chains are manufactured from premium materials, heat-treated, pre-stressed and engineered for a perfect chain-to-sprocket tooth fit €” delivering quiet operation, durability, and OE-level performance you can count on. To ensure total timing system integrity, Cloyes recommends replacing the chain along with the tensioners, guides, and sprockets during service. Trusted by professionals for over a century & backed by an industry-leading warranty and technical support.
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ACDelco – ACDelco Timing Chain, 12646386 (Part No.12646386)

ACDelco Timing Chain, 12646386

from

$75.99
ACDelco GM Original Equipment Engine Timing Chains synchronize the rotation of the crankshaft and camshaft(s) in an internal combustion engine. They help ensure that the engine’s valves open and close at the proper time during each cylinder’s intake and exhaust strokes, and are GM-recommended replacements for your vehicle’s original components. These original equipment timing chains have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.
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Cloyes Performance – Cloyes Performance High Performance Timing Set, 9-3678X5Z (Part No.9-3678X5Z)

Cloyes Performance High Performance Timing Set, 9-3678X5Z

from

$264.99
“Cloyes Performance Tensioner Elimination GM LT Engine Timing “”Z”” chain det eliminates the factory tensioner while maintaining tunable accurate timing for VVT-equipped LT engines. By removing the factory tensioner, this kit eliminates chain slack and potential failure. The “”Z”” chain offers superior strength and durability for VVT LT engines, reducing the risk of chain stretch or fatigue. The combination of Cloyes TRUE Roller “”Z”” Chain and precision-machined sprockets ensures a center distance corrected timing drive for extreme performance on VVT-equipped LT engines.”
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Cloyes Performance – Cloyes Performance High Performance Timing Set, 9-3678X5 (Part No.9-3678X5)

Cloyes Performance High Performance Timing Set, 9-3678X5

from

$139.99
Cloyes Performance Tensioner Elimination GM LT Engine Timing Set eliminates the factory tensioner while maintaining tunable accurate timing for VVT-equipped LT engines. By removing the factory tensioner, this kit eliminates chain slack and potential failure. The combination of Cloyes TRUE Roller chain, and precision-machined sprockets ensures a center distance corrected timing drive for reliable performance on VVT-equipped LT engines.
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Cloyes Gear – Cloyes Gear Engine Timing Chain Kit, 9-4205SC (Part No.9-4205SC)

Cloyes Gear Engine Timing Chain Kit, 9-4205SC

from

$125.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems delivering premium-quality solutions. Cloyes engine timing chain kits are engineered for precision, durability, and optimal engine performance. Kits include all chains, sprockets, tensioners, chain guides, and chain tensioner guides – respective to application and kit selection. To ensure total timing system integrity, Cloyes recommends replacing all engine timing components. Trusted by professionals for over a century & backed by an industry-leading warranty and technical support.
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Cloyes Gear – Cloyes Gear Engine Timing Crankshaft Sprocket, S1111 (Part No.S1111)

Cloyes Gear Engine Timing Crankshaft Sprocket, S1111

from

$80.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems. As a critical component of the engine’s timing system, the crankshaft sprockets work in unison with the timing chain, tensioners, guides and other sprockets, to ensure precise timing. Cloyes engine timing crankshaft sprockets are precision-tooled with exact tooth geometry and a perfectly matched bore, off-set and timing index for superior fit, reliability, and long-term performance. To ensure total timing system integrity, Cloyes recommends replacing the chain along with the tensioners, guides, and sprockets during service. Trusted by professionals for over a century & backed by an industry-leading Warranty (limited) and technical support. 
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Cloyes Gear – Cloyes Gear Engine Timing Chain Kit, 9-4205SCX (Part No.9-4205SCX)

Cloyes Gear Engine Timing Chain Kit, 9-4205SCX

from

$67.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems delivering premium-quality solutions. Cloyes engine timing chain kits are engineered for precision, durability, and optimal engine performance. Kits include all chains, sprockets, tensioners, chain guides, and chain tensioner guides – respective to application and kit selection. To ensure total timing system integrity, Cloyes recommends replacing all engine timing components. Trusted by professionals for over a century & backed by an industry-leading warranty and technical support.
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Cloyes Gear – Cloyes Gear Engine Timing Chain Tensioner, 9-5977 (Part No.9-5977)

Cloyes Gear Engine Timing Chain Tensioner, 9-5977

from

$31.99
Since 1921, Cloyes has been the trusted leader in automotive timing systems, delivering premium-quality solutions. A timing chain tensioner maintains appropriate tension in the timing chain. Depending on design and application, Cloyes engine timing chain tensioners can use spring tension or hydraulic pressure to properly tension the chain for optimal performance. To ensure total timing system integrity, Cloyes recommends replacing the chain along with the tensioners, guides, and sprockets during service. Trusted by professionals for over a century & backed by an industry-leading Warranty (limited) and technical support.
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FAQs for 2021 GMC Sierra 2500 HD Engine Parts

Which Engine Parts are best-sellers for 2021 GMC Sierra 2500 HDs?

Out of 47 Engine Parts that fit 2021 GMC Sierra 2500 HDs, the following parts are the top sellers:

What’s the price range for 2021 GMC Sierra 2500 HD Engine Parts?

Engine Part prices for the 2021 GMC Sierra 2500 HD start at $0.99 and go up to $689.99 for the most premium parts.

What’s the average price of a Engine Part for a 2021 GMC Sierra 2500 HD?

The average price for Engine Parts for the 2021 GMC Sierra 2500 HD is $70.97. Keep in mind the variety of part types within our Engine Part category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Parts for other GMC Sierra 2500 HD model years?

Yes, we currently carry Engine Parts for 24 model years of GMC Sierra 2500 HDs between 2001 and 2026. Engine Parts are bought most frequently for the following model years: 2023, 2022, 2020, 2019, 2018, 2017, 2016, 2015, and 2014.

What are the cheapest Engine Parts for my 2021 GMC Sierra 2500 HD?

The cheapest 2021 GMC Sierra 2500 HD Engine Parts we carry in stock are:

Can I get help with 2021 GMC Sierra 2500 HD Engine Part orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Engine Parts and more.

What is your return policy for GMC Sierra 2500 HD Engine Parts?

Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Engine Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.