2016 Mercedes-Benz E250 Drivetrains
Find Your Specific 2016 Mercedes-Benz E250 Drivetrains
Below you will find various in-demand Mercedes-Benz Drivetrains, components and accessories for your 2016 E250. Advance Auto Parts has popular E250 parts like Spindles, Differentials, Transfer Cases and more. You’ll also find aftermarket and OEM Drivetrains for other E250 model years including
2014
2015 and more. Select a category of 2016 Mercedes-Benz E250 Drivetrains below and start saving instantly.
Popular 2016 Mercedes-Benz E250 Drivetrains Categories
Essential Drivetrains for 2016 Mercedes-Benz E250s
National – Differential Pinion Seal (Part No.710996)
from
$20.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -30 Deg. F to 325 Deg. F / -34 Deg. C to 163 Deg. C
- Superior thermal and chemical resistance
- Good abrasion and dry running capability
- Delivers quality and reliable performance for every type of repair
Carquest Premium – CV Axle Assembly (Part No.NCV48068)
from
$174.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
Product Features:
See More
Product Features:
- Designed to meet or exceed OE specifications for fit, form and function
- 100% new axle and components
- New axle nut or attaching hardware included when applicable
- Bearings, races and housings are heat-treated for longer life
- Precision-engineered seal mating surfaces for leak-free performance
- High moly CV joint grease with stainless-steel boot bands
Carquest Premium – CV Axle Assembly (Part No.NCV48022)
from
$188.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
Product Features:
See More
Product Features:
- Designed to meet or exceed OE specifications for fit, form and function
- 100% new axle and components
- New axle nut or attaching hardware included when applicable
- Bearings, races and housings are heat-treated for longer life
- Precision-engineered seal mating surfaces for leak-free performance
- High moly CV joint grease with stainless-steel boot bands
Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)
from
$12.49
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA
Product Features:
See More
Product Features:
- FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
- HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
- IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
- ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
Dorman – Spindle Nut M26-1.50 – Hex Size 32mm (sold by each) (Part No.615-261)
from
$78.99
Spindle Nut M26-1.50 – Hex Size 32mm (sold by each)
MOOG Hub Assemblies – Wheel Hub Repair Kit (Part No.520001)
from
$367.99
By constantly introducing design enhancements that extend product life and simplify installation and replacement, MOOG has earned its reputation as the chassis industry’s Problem Solver.
Product Features:
See More
Product Features:
- MOOG hub assemblies are performance proven, quality tested and are available for a broad range of foreign and domestic vehicles.
- Engineered to overcome problems and deliver smooth, reliable performance.
- Application specific design
- MOOG is the official steering and suspension of NASCAR
Rein – Drive Shaft Support Bearing (Part No.BEM0039P)
from
$16.99
Drive Shaft Support Bearing
National – Multi-Purpose Bearing (Part No.106-CC)
from
$23.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.
Product Features:
See More
Product Features:
- BUILT TO LAST — Advanced heat treatment process for strength
- PREMIUM MATERIALS — Precision manufactured using premium-grade steel for lasting performance and extended bearing life
- RELIABLE PERFORMANCE — Element size and quantity are engineered to meet or exceed the load rating of OE bearings
- COMPREHENSIVE COVERAGE — Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING — Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Driveworks – Wheel Bearing and Hub Assembly: Includes Spindle Hub + Wheel Bearing (pre-pressed) (Part No.NT520001)
from
$129.99
Driveworks wheel hub assemblies are made with high precision through state-of-the-art technology and manufactured with strict quality-control criteria. Every wheel hub assembly is specifically designed to fit the designated applications and may be used as a direct replacement for the original part. Each part is engineered using OE data and measurements to ensure fitment, performance, and longevity.
Product Features:
See More
Product Features:
- Fitment and function are ensured by precision machining, rigorous testing, and meticulous inspection of material and components.
- Driveworks wheel hub assemblies are designed to meet stringent fatigue requirements in order to reduce premature failure.
- Reinforced seal design material allows for optimal performance in harsh environments.
- Driveworks wheel hub assemblies undergo heat treatment and cold-forming processes that harden the surface ensuring high-temperature resistance and durability.
- Where applicable, pre-installed speed sensors will automatically sync to the vehicle’s anti-lock braking system upon successful installation and provide accurate speed-reading data.
- Brand may vary by location
National – Multi-Purpose Bearing (Part No.206)
from
$24.99
Designed to meet or exceed OE quality, premium-quality bearings from National are manufactured to exacting standards to deliver lasting performance and extended bearing life.
Product Features:
See More
Product Features:
- BUILT TO LAST: Advanced heat treatment process for strength
- PREMIUM MATERIALS: Precision manufactured using premium-grade steel for lasting performance and extended bearing life
- RELIABLE PERFORMANCE: Element size and quantity are engineered to meet or exceed the load rating of OE bearings
- COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Rein – Driveshaft Boot (Part No.BKD0066R)
from
$6.99
Boot kits protect a joint in the car that would be destroyed by dirt, sand and other particles if left exposed, even under normal conditions so it’s important that they be properly maintained and in good condition. Rein Automotive provides application specific driveshaft boot kits that come guaranteed to fit the first time.
See More
Upgrade your 2016 Mercedes-Benz E250 with Top-Quality Drivetrains
When it comes to maintaining or upgrading your 2016 Mercedes-Benz E250, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Mercedes-Benz or enhancing its overall performance, Drivetrains are key to keeping your E250 functioning at its best. At Advance Auto Parts, we offer a wide selection of 11 Drivetrains for the 2016 Mercedes-Benz E250, designed to meet your needs without breaking the bank.
From
Spindle
replacements to
Differentials
upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.
Affordable Prices and Wide Selection
Shopping for Drivetrains for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Drivetrains for your 2016 Mercedes-Benz E250 at great prices.
Our Drivetrains inventory for this model
ranges from just $6.99 to $367.99, with
an average price of $68.47.
Our 11 Drivetrains in stock come from 7 trusted brands, so you’re sure to find the right part for your 2016 Mercedes-Benz E250 without overspending.
Top Brands and High Customer Satisfaction
Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2016 Mercedes-Benz E250, we stock popular OEM and aftermarket Drivetrains from top names
like Valvoline, and more.
Valvoline Drivetrains
start at just $12.49 and boast an impressive 4.8 stars average rating from customers.
With 892 customer reviews and counting, our 2016 Mercedes-Benz E250 Drivetrains have a strong track record of reliability, ensuring you can trust your purchase.
Explore Related Parts and More
While you’re here, don’t forget to check out other essential categories that go hand in hand with Drivetrain upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants
and more to make sure your 2016 Mercedes-Benz E250 is always ready to roll. We’re committed to providing you with everything you need to keep your E250 in top shape, all in one place.
Start shopping confidently below for your 2016 Mercedes-Benz E250!
Best-Selling Spindles for 2016 Mercedes-Benz E250s
Enhance the driving experience in your Mercedes-Benz with 1 quality Spindle components, starting at $78.99.
Dorman – Spindle Nut M26-1.50 – Hex Size 32mm (sold by each) (Part No.615-261)
from
$78.99
Spindle Nut M26-1.50 – Hex Size 32mm (sold by each)
Most Popular 2016 Mercedes-Benz E250 Differentials
Customize your Mercedes-Benz with 2 Differentials products
like Differential Oil and
Differential Pinion Seals, all
priced under $20.79.
Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)
from
$12.49
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA
Product Features:
See More
Product Features:
- FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
- HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
- IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
- ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
National – Differential Pinion Seal (Part No.710996)
from
$20.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
Product Features:
See More
Product Features:
- Design type: spring loaded; multi-lip
- Temperature range: -30 Deg. F to 325 Deg. F / -34 Deg. C to 163 Deg. C
- Superior thermal and chemical resistance
- Good abrasion and dry running capability
- Delivers quality and reliable performance for every type of repair
Top Picks for 2016 Mercedes-Benz E250 Transfer Cases
Upgrade Mercedes-Benz E250s with top-quality Transfer Cases parts, including 1 OEM and aftermarket selections for your 2016 model.
National – Multi-Purpose Bearing (Part No.206)
from
$24.99
Designed to meet or exceed OE quality, premium-quality bearings from National are manufactured to exacting standards to deliver lasting performance and extended bearing life.
Product Features:
See More
Product Features:
- BUILT TO LAST: Advanced heat treatment process for strength
- PREMIUM MATERIALS: Precision manufactured using premium-grade steel for lasting performance and extended bearing life
- RELIABLE PERFORMANCE: Element size and quantity are engineered to meet or exceed the load rating of OE bearings
- COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
In-Demand Drive Shafts and Axles for 2016 Mercedes-Benz E250s
Select from 5 premium Drive Shafts and Axles parts for your 2016 Mercedes-Benz E250, with prices ranging from $6.99 to $188.99.
National – Multi-Purpose Bearing (Part No.106-CC)
from
$23.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.
Product Features:
See More
Product Features:
- BUILT TO LAST — Advanced heat treatment process for strength
- PREMIUM MATERIALS — Precision manufactured using premium-grade steel for lasting performance and extended bearing life
- RELIABLE PERFORMANCE — Element size and quantity are engineered to meet or exceed the load rating of OE bearings
- COMPREHENSIVE COVERAGE — Industry-leading coverage for domestic and import applications
- RIGOROUS TESTING — Comprehensive testing throughout design and development processes by National engineers for quality you can count on
Rein – Drive Shaft Support Bearing (Part No.BEM0039P)
from
$16.99
Drive Shaft Support Bearing
Rein – Driveshaft Boot (Part No.BKD0066R)
from
$6.99
Boot kits protect a joint in the car that would be destroyed by dirt, sand and other particles if left exposed, even under normal conditions so it’s important that they be properly maintained and in good condition. Rein Automotive provides application specific driveshaft boot kits that come guaranteed to fit the first time.
See More
Carquest Premium – CV Axle Assembly (Part No.NCV48022)
from
$188.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
Product Features:
See More
Product Features:
- Designed to meet or exceed OE specifications for fit, form and function
- 100% new axle and components
- New axle nut or attaching hardware included when applicable
- Bearings, races and housings are heat-treated for longer life
- Precision-engineered seal mating surfaces for leak-free performance
- High moly CV joint grease with stainless-steel boot bands
Carquest Premium – CV Axle Assembly (Part No.NCV48068)
from
$174.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
Product Features:
See More
Product Features:
- Designed to meet or exceed OE specifications for fit, form and function
- 100% new axle and components
- New axle nut or attaching hardware included when applicable
- Bearings, races and housings are heat-treated for longer life
- Precision-engineered seal mating surfaces for leak-free performance
- High moly CV joint grease with stainless-steel boot bands
Most Sold 2016 Mercedes-Benz E250 Hubs and Hub Assemblies
Explore our best-selling Mercedes-Benz parts for the 2016 E250 among 2 OEM and aftermarket options starting from $129.99.
MOOG Hub Assemblies – Wheel Hub Repair Kit (Part No.520001)
from
$367.99
By constantly introducing design enhancements that extend product life and simplify installation and replacement, MOOG has earned its reputation as the chassis industry’s Problem Solver.
Product Features:
See More
Product Features:
- MOOG hub assemblies are performance proven, quality tested and are available for a broad range of foreign and domestic vehicles.
- Engineered to overcome problems and deliver smooth, reliable performance.
- Application specific design
- MOOG is the official steering and suspension of NASCAR
Driveworks – Wheel Bearing and Hub Assembly: Includes Spindle Hub + Wheel Bearing (pre-pressed) (Part No.NT520001)
from
$129.99
Driveworks wheel hub assemblies are made with high precision through state-of-the-art technology and manufactured with strict quality-control criteria. Every wheel hub assembly is specifically designed to fit the designated applications and may be used as a direct replacement for the original part. Each part is engineered using OE data and measurements to ensure fitment, performance, and longevity.
Product Features:
See More
Product Features:
- Fitment and function are ensured by precision machining, rigorous testing, and meticulous inspection of material and components.
- Driveworks wheel hub assemblies are designed to meet stringent fatigue requirements in order to reduce premature failure.
- Reinforced seal design material allows for optimal performance in harsh environments.
- Driveworks wheel hub assemblies undergo heat treatment and cold-forming processes that harden the surface ensuring high-temperature resistance and durability.
- Where applicable, pre-installed speed sensors will automatically sync to the vehicle’s anti-lock braking system upon successful installation and provide accurate speed-reading data.
- Brand may vary by location
Top-Rated Drivetrains Brands For Your 2016 Mercedes-Benz E250
Shop for the best-rated brands offering Drivetrains and other products for your 2016 Mercedes-Benz E250s. Below you’ll find some of our best rated Drivetrains from Valvoline, and more. Drivetrains from these brands that fit a 2016 E250 start at just $12.49 and are rated as high as 4.8 stars. OEM and aftermarket Drivetrains don’t get more top quality, durable, and affordable than from the brands below.
Popular Valvoline 2016 Mercedes-Benz E250 Drivetrains
When it comes to maintaining or upgrading your 2016 Mercedes-Benz E250, using quality Drivetrains is essential to ensure durability and a perfect fit. Valvoline ticks all of those boxes. We offer a wide selection of Valvoline Drivetrains, specifically designed for the 2016 Mercedes-Benz E250. With over 1 Valvoline brand Drivetrains in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $12.49. Plus, with over 446 customer reviews and an average rating of 4.8 stars, you can trust that our Valvoline Drivetrains will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
from
$12.49
(446)
MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart
“seems to be ok”
FAQs for 2016 Mercedes-Benz E250 Drivetrains
Which Drivetrains are best-sellers for 2016 Mercedes-Benz E250s?
Out of 11 Drivetrains that fit 2016 Mercedes-Benz E250s, the following parts are the top sellers:
- Multi-Purpose Bearing (3273024) – $24.99
- Multi-Purpose Bearing (3272109) – $23.99
- Driveshaft Boot (11325016) – $6.99
What’s the price range for 2016 Mercedes-Benz E250 Drivetrains?
Drivetrain prices for the 2016 Mercedes-Benz E250 start at $6.99 and go up to $367.99 for the most premium parts.
What’s the average price of a Drivetrain for a 2016 Mercedes-Benz E250?
The average price for Drivetrains for the 2016 Mercedes-Benz E250 is $68.47. Keep in mind the variety of part types within our Drivetrain category so you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Drivetrains for other Mercedes-Benz E250 model years?
What are the cheapest Drivetrains for my 2016 Mercedes-Benz E250?
The cheapest 2016 Mercedes-Benz E250 Drivetrains we carry in stock are:
- Driveshaft Boot (11325016) – $6.99
- MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (8020023) – $12.49
- Drive Shaft Support Bearing (11324475) – $16.99
- Differential Pinion Seal (12067756) – $20.79
- Multi-Purpose Bearing (3272109) – $23.99
What are the top-rated Drivetrains that fit the 2016 Mercedes-Benz E250?
Out of 892 reviews by customers, our 2016 Mercedes-Benz E250 Drivetrains have an average customer rating of . These are some of the highest-rated Drivetrain types for the 2016 Mercedes-Benz E250 and their top-rated products:
- Differentials
What types of Drivetrains do you sell for my 2016 Mercedes-Benz E250?
As of 6/2/26, these are some of the most in-demand types of Drivetrains for a 2016 Mercedes-Benz E250:
Can I get help with 2016 Mercedes-Benz E250 Drivetrain orders?
Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Drivetrains and more.
What is your return policy for Mercedes-Benz E250 Drivetrains?
Advance Auto Parts keeps returns simple. For new Mercedes-Benz E250 Drivetrains and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.
