2012 Mercedes-Benz E350 Drive Shafts and Axles

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Keep Your 2012 Mercedes-Benz E350 in Top Shape with Quality Drive Shafts and Axles

Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2012 Mercedes-Benz E350 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Center Support Bearings, Drive Shaft Boots, and Drive Shaft Couplings. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2012 Mercedes-Benz E350 Drive Shafts and Axle at Advance Auto Parts is around $415.56, with a range that starts at $6.99 and goes up to $1,283.99. With 11 options in stock from 4 trusted brands, finding the right fit is easy. Popular picks like Multi-Purpose Bearing, Drive Shaft Support Bearing, and One-Piece Steel Driveshaft Assembly (OE Fix) start at just $15.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Differentials and Hubs and Hub Assemblies. At Advance Auto Parts, we’re here to help you keep your 2012 Mercedes-Benz E350 in peak condition, inside and out.

Essential 2012 Mercedes-Benz E350 Drive Shafts and Axles

Carquest Premium – CV Axle Assembly (Part No.NCV48022)

CV Axle Assembly

from

$188.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Assembly (Part No.NCV48084)

CV Axle Assembly

from

$198.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Assembly (Part No.NCV48068)

CV Axle Assembly

from

$174.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Dorman – Driveshaft Flex Coupler (Part No.935-910)

Driveshaft Flex Coupler

from

$168.99
This drive shaft coupler is designed to match the fit and function of the original coupler on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft coupler is designed to match the fit and function of the original coupler on specified vehicles
  • Restores functionality – reliable replacement for an original coupler that has failed due to wear or damaged due to collision
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Driveshaft Flex Coupler (Part No.935-511)

Driveshaft Flex Coupler

from

$333.99
This drive shaft coupler is designed to match the fit and function of the original coupler on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft coupler is designed to match the fit and function of the original coupler on specified vehicles
  • Restores functionality – reliable replacement for an original coupler that has failed due to wear or damaged due to collision
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Rein – Drive Shaft Support Bearing (Part No.BEM0039P)

Drive Shaft Support Bearing

from

$15.99
Drive Shaft Support Bearing

National – Multi-Purpose Bearing (Part No.106-CC)

Multi-Purpose Bearing

from

$23.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • BUILT TO LAST — Advanced heat treatment process for strength
  • PREMIUM MATERIALS — Precision manufactured using premium-grade steel for lasting performance and extended bearing life
  • RELIABLE PERFORMANCE — Element size and quantity are engineered to meet or exceed the load rating of OE bearings
  • COMPREHENSIVE COVERAGE — Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Dorman – One-Piece Steel Driveshaft Assembly (OE Fix) (Part No.938-241)

One-Piece Steel Driveshaft Assembly (OE Fix)

from

$1283.99
The original drive shafts on specific vehicles have permanently staked universal joints that make servicing difficult. This Dorman OE FIX front drive shaft makes the U-joints serviceable for simpler maintenance.

Product Features:
  • Ready to install – this drive shaft is shipped pre-assembled and factory balanced to ensure immediate smooth operation
  • Simplifies repair – this replacement makes the U-joints serviceable for simpler maintenance
  • All-new manufacturing – made 100% new, not remanufactured, so there’s no core charge or return hassle
  • Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
See More

Dorman – Drive Shaft: Adjustable (Part No.976-542)

Drive Shaft: Adjustable

from

$984.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.976-181)

Drive Shaft: Greaseable, Adjustable

from

$1080.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft (Part No.986-038)

Drive Shaft

from

$1002.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – One-Piece Steel Driveshaft Assembly (OE Fix) (Part No.936-037)

One-Piece Steel Driveshaft Assembly (OE Fix)

from

$792.99
The original drive shafts on specific vehicles have permanently staked universal joints that make servicing difficult. This Dorman OE FIX front drive shaft makes the U-joints serviceable for simpler maintenance.

Product Features:
  • Ready to install – this drive shaft is shipped pre-assembled and factory balanced to ensure immediate smooth operation
  • Simplifies repair – this replacement makes the U-joints serviceable for simpler maintenance
  • All-new manufacturing – made 100% new, not remanufactured, so there’s no core charge or return hassle
  • Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
See More

Dorman – One-Piece Steel Driveshaft Assembly (OE Fix) (Part No.936-331)

One-Piece Steel Driveshaft Assembly (OE Fix)

from

$478.99
The original drive shafts on specific vehicles have permanently staked universal joints that make servicing difficult. This Dorman OE FIX front drive shaft makes the U-joints serviceable for simpler maintenance.

Product Features:
  • Ready to install – this drive shaft is shipped pre-assembled and factory balanced to ensure immediate smooth operation
  • All-new manufacturing – made 100% new, not remanufactured, so there’s no core charge or return hassle
  • Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
  • Simplifies repair – this replacement makes the U-joints serviceable for simpler maintenance
See More

Dorman – Drive Shaft: Adjustable (Part No.976-545)

Drive Shaft: Adjustable

from

$946.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Adjustable (Part No.976-783)

Drive Shaft: Adjustable

from

$1025.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft (Part No.986-036)

Drive Shaft

from

$832.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Driveshaft Assembly (Part No.938-353)

Driveshaft Assembly

from

$689.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Rein – Driveshaft Boot (Part No.BKD0066R)

Driveshaft Boot

from

$6.99
Boot kits protect a joint in the car that would be destroyed by dirt, sand and other particles if left exposed, even under normal conditions so it’s important that they be properly maintained and in good condition. Rein Automotive provides application specific driveshaft boot kits that come guaranteed to fit the first time.
See More

Most Popular Center Support Bearings for 2012 Mercedes-Benz E350s

Enhance your 2012 Mercedes-Benz E350 with one of the 2 Center Support Bearings we have in stock, starting at just $15.99.

National – Multi-Purpose Bearing (Part No.106-CC)

Multi-Purpose Bearing

from

$23.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • BUILT TO LAST — Advanced heat treatment process for strength
  • PREMIUM MATERIALS — Precision manufactured using premium-grade steel for lasting performance and extended bearing life
  • RELIABLE PERFORMANCE — Element size and quantity are engineered to meet or exceed the load rating of OE bearings
  • COMPREHENSIVE COVERAGE — Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING — Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Rein – Drive Shaft Support Bearing (Part No.BEM0039P)

Drive Shaft Support Bearing

from

$15.99
Drive Shaft Support Bearing

Best-Selling 2012 Mercedes-Benz E350 Drive Shaft Boot

Upgrade your E350 with our best-selling Drive Shaft Boot.

Rein – Driveshaft Boot (Part No.BKD0066R)

Driveshaft Boot

from

$6.99
Boot kits protect a joint in the car that would be destroyed by dirt, sand and other particles if left exposed, even under normal conditions so it’s important that they be properly maintained and in good condition. Rein Automotive provides application specific driveshaft boot kits that come guaranteed to fit the first time.
See More

Top-Quality Drive Shaft Couplings for 2012 Mercedes-Benz E350s

Choose a high-quality OEM or aftermarket Drive Shaft Coupling for Mercedes-Benz E350s and enjoy top-notch performance from $333.99.

Dorman – Driveshaft Flex Coupler (Part No.935-511)

Driveshaft Flex Coupler

from

$333.99
This drive shaft coupler is designed to match the fit and function of the original coupler on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft coupler is designed to match the fit and function of the original coupler on specified vehicles
  • Restores functionality – reliable replacement for an original coupler that has failed due to wear or damaged due to collision
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Top Picks for 2012 Mercedes-Benz E350 Drive Shaft and Axles

Invest in one of our 2 durable Drive Shaft and Axles for your 2012 Mercedes-Benz, knowing you’re getting trusted brands and expert craftsmanship.

Carquest Premium – CV Axle Assembly (Part No.NCV48022)

CV Axle Assembly

from

$188.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Assembly (Part No.NCV48068)

CV Axle Assembly

from

$174.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Drive and Prop Shaft Assemblies for 2012 Mercedes-Benz E350s

Make a smart move for your 2012 Mercedes-Benz E350 with products all priced from $832.99 to $1,283.99.

Dorman – One-Piece Steel Driveshaft Assembly (OE Fix) (Part No.938-241)

One-Piece Steel Driveshaft Assembly (OE Fix)

from

$1283.99
The original drive shafts on specific vehicles have permanently staked universal joints that make servicing difficult. This Dorman OE FIX front drive shaft makes the U-joints serviceable for simpler maintenance.

Product Features:
  • Ready to install – this drive shaft is shipped pre-assembled and factory balanced to ensure immediate smooth operation
  • Simplifies repair – this replacement makes the U-joints serviceable for simpler maintenance
  • All-new manufacturing – made 100% new, not remanufactured, so there’s no core charge or return hassle
  • Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
See More

Dorman – Drive Shaft: Adjustable (Part No.976-783)

Drive Shaft: Adjustable

from

$1025.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft (Part No.986-038)

Drive Shaft

from

$1002.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Adjustable (Part No.976-542)

Drive Shaft: Adjustable

from

$984.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft (Part No.986-036)

Drive Shaft

from

$832.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

FAQs for 2012 Mercedes-Benz E350 Drive Shafts and Axles

What are the best-selling Drive Shafts and Axles for 2012 Mercedes-Benz E350s?

Out of 11 Drive Shafts and Axles that fit 2012 Mercedes-Benz E350s, the following parts are the top sellers:

What’s the price range for 2012 Mercedes-Benz E350 Drive Shafts and Axles?

The prices of Drive Shafts and Axles for the 2012 Mercedes-Benz E350 range from $6.99 up to $1,283.99 for the most premium parts.

What is the average price of a Drive Shafts and Axle for a 2012 Mercedes-Benz E350?

The average price for Drive Shafts and Axles for the 2012 Mercedes-Benz E350 is $415.56. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drive Shafts and Axles for other Mercedes-Benz E350 model years?

Yes, we carry Drive Shafts and Axles for 14 model years of Mercedes-Benz E350s between 2006 and 2024. The following model years are the most popular for Drive Shafts and Axle purchases: 2023, 2022, 2021, 2020, 2016, 2015, 2014, 2013, and 2011.

What are the cheapest Drive Shafts and Axles for my 2012 Mercedes-Benz E350?

The cheapest 2012 Mercedes-Benz E350 Drive Shafts and Axles we carry are:

Does Advance Auto Parts sell Drive Shafts and Axles for any other 2012 Mercedes-Benz models?

Yes. We stock Drive Shafts and Axles for 33 other popular 2012 Mercedes-Benz models. Some of the most popular are 2012 SLK55 AMG Drive Shafts and Axles, 2012 SLK350 Drive Shafts and Axles, 2012 S600 Drive Shafts and Axles, 2012 C350 Drive Shafts and Axles, and 2012 E550 Drive Shafts and Axles.

What types of Drive Shafts and Axles do you sell for my 2012 Mercedes-Benz E350?

As of 3/1/26, these are some of the most in-demand types of Drive Shafts and Axles for a 2012 Mercedes-Benz E350:

Can I get help with 2012 Mercedes-Benz E350 Drive Shafts and Axle orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Drive Shafts and Axles and more.

What is your return policy for Mercedes-Benz E350 Drive Shafts and Axles?

Advance Auto Parts keeps returns simple. For new Mercedes-Benz E350 Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.