2010 Lexus IS250 Drive Shafts and Axles

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Keep Your 2010 Lexus IS250 in Top Shape with Quality Drive Shafts and Axles

Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2010 Lexus IS250 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Center Support Bearings, Drive and Prop Shaft Assemblies, and Drive Shaft and Axles. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2010 Lexus IS250 Drive Shafts and Axle at Advance Auto Parts is around $479.44, with a range that starts at $117.99 and goes up to $1,215.00. With 5 options in stock from 3 trusted brands, finding the right fit is easy. Popular picks like CV Axle Shaft Assembly, Center Support Bearing Center, and Drive Shaft start at just $137.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Differentials and Spindles. At Advance Auto Parts, we’re here to help you keep your 2010 Lexus IS250 in peak condition, inside and out.

Essential 2010 Lexus IS250 Drive Shafts and Axles

Anchor – Center Support Bearing Center (Part No.6098)

Center Support Bearing Center

from

$137.99
Anchor 6098 Center support bearings support a driveshaft between transmission and differential. This mount relieves stress on driveline components. Each part is engineered and designed to OE Standards. Natural and SBR rubber provide maximum life and performance. Steel fasteners are heat treated grade 5 bolts. A special bonding agent is used to ensure a rubber to metal bond. Rubber material is mixed to specific Durometer, hardness.

Product Features:
See More

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV546200)

CV Axle Shaft Assembly

from

$171.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Assembly (Part No.NCV69272)

CV Axle Assembly

from

$151.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV546206)

CV Axle Shaft Assembly

from

$117.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Assembly (Part No.NCV69273)

CV Axle Assembly

from

$153.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Dorman – Drive Shaft: Adjustable (Part No.976-759)

Drive Shaft: Adjustable

from

$1029.00
Upgrade and simplify your driveshaft replacement with a premium driveshaft that’s delivered fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years. Engineered and manufactured in the USA, the driveshaft is manufactured from high-precision, drawn over mandrel (DOM) seamless steel tubing that offers superior concentricity, uniform wall thickness and greater torsional strength and dent resistance than standard welded steel. The assembly includes 100% new-not remanufactured-components, including yokes, CV joints and U-joints. A premium quality driveshaft assembly deserves premium packaging; this product ships in protective foam-in-place packaging to ensure it arrives in the same pristine, install-ready condition in which it left the manufacturing facility.

Product Features:
  • Ready to install – this premium driveshaft assembly arrives fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years
  • Premium shaft – made from drawn over mandrel (DOM) seamless steel tubing for superior concentricity, uniform wall thickness and more torsional strength and dent resistance than standard welded steel
  • All-new construction – built in the USA with 100% new-not remanufactured-tubing, yokes, CV joints, and U-joints
  • Superior packaging – assembly ships in protective foam-in-place packaging to ensure it is delivered in the same pristine, install-ready condition in which it left the manufacturing facility
See More

Dorman – Drive Shaft (Part No.986-166)

Drive Shaft

from

$1177.00
Upgrade and simplify your driveshaft replacement with a premium driveshaft that’s delivered fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years. Engineered and manufactured

Product Features:
  • Ready to install – this premium driveshaft assembly arrives fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years
  • Premium shaft – made from drawn over mandrel (DOM) seamless steel tubing for superior concentricity, uniform wall thickness and more torsional strength and dent resistance than standard welded steel
  • All-new construction – built in the USA with 100% new-not remanufactured-tubing, yokes, CV joints, and U-joints
  • Superior packaging – assembly ships in protective foam-in-place packaging to ensure it is delivered in the same pristine, install-ready condition in which it left the manufacturing facility
See More

Dorman – Drive Shaft (Part No.986-148)

Drive Shaft

from

$1215.00
Upgrade and simplify your driveshaft replacement with a premium driveshaft that’s delivered fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years. Engineered and manufactured

Product Features:
  • Ready to install – this premium driveshaft assembly arrives fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years
  • Premium shaft – made from drawn over mandrel (DOM) seamless steel tubing for superior concentricity, uniform wall thickness and more torsional strength and dent resistance than standard welded steel
  • All-new construction – built in the USA with 100% new-not remanufactured-tubing, yokes, CV joints, and U-joints
  • Superior packaging – assembly ships in protective foam-in-place packaging to ensure it is delivered in the same pristine, install-ready condition in which it left the manufacturing facility
See More

Most Popular Center Support Bearing for 2010 Lexus IS250s

Enhance your 2010 Lexus IS250 with this popular Center Support Bearing we have in stock, for $137.99.

Anchor – Center Support Bearing Center (Part No.6098)

Center Support Bearing Center

from

$137.99
Anchor 6098 Center support bearings support a driveshaft between transmission and differential. This mount relieves stress on driveline components. Each part is engineered and designed to OE Standards. Natural and SBR rubber provide maximum life and performance. Steel fasteners are heat treated grade 5 bolts. A special bonding agent is used to ensure a rubber to metal bond. Rubber material is mixed to specific Durometer, hardness.

Product Features:
See More

Best-Selling 2010 Lexus IS250 Drive and Prop Shaft Assemblies

Upgrade your IS250 with one of our 2 best-selling Drive and Prop Shaft Assemblies.

Dorman – Drive Shaft (Part No.986-148)

Drive Shaft

from

$1215.00
Upgrade and simplify your driveshaft replacement with a premium driveshaft that’s delivered fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years. Engineered and manufactured

Product Features:
  • Ready to install – this premium driveshaft assembly arrives fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years
  • Premium shaft – made from drawn over mandrel (DOM) seamless steel tubing for superior concentricity, uniform wall thickness and more torsional strength and dent resistance than standard welded steel
  • All-new construction – built in the USA with 100% new-not remanufactured-tubing, yokes, CV joints, and U-joints
  • Superior packaging – assembly ships in protective foam-in-place packaging to ensure it is delivered in the same pristine, install-ready condition in which it left the manufacturing facility
See More

Dorman – Drive Shaft: Adjustable (Part No.976-759)

Drive Shaft: Adjustable

from

$1029.00
Upgrade and simplify your driveshaft replacement with a premium driveshaft that’s delivered fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years. Engineered and manufactured in the USA, the driveshaft is manufactured from high-precision, drawn over mandrel (DOM) seamless steel tubing that offers superior concentricity, uniform wall thickness and greater torsional strength and dent resistance than standard welded steel. The assembly includes 100% new-not remanufactured-components, including yokes, CV joints and U-joints. A premium quality driveshaft assembly deserves premium packaging; this product ships in protective foam-in-place packaging to ensure it arrives in the same pristine, install-ready condition in which it left the manufacturing facility.

Product Features:
  • Ready to install – this premium driveshaft assembly arrives fully assembled, dynamically pre-balanced and ready for a fast, hassle-free installation on specified vehicle makes, models and years
  • Premium shaft – made from drawn over mandrel (DOM) seamless steel tubing for superior concentricity, uniform wall thickness and more torsional strength and dent resistance than standard welded steel
  • All-new construction – built in the USA with 100% new-not remanufactured-tubing, yokes, CV joints, and U-joints
  • Superior packaging – assembly ships in protective foam-in-place packaging to ensure it is delivered in the same pristine, install-ready condition in which it left the manufacturing facility
See More

Top-Quality Drive Shaft and Axles for 2010 Lexus IS250s

Choose a high-quality OEM or aftermarket Drive Shaft and Axle for Lexus IS250s and enjoy top-notch performance from $117.99.

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV546206)

CV Axle Shaft Assembly

from

$117.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV546200)

CV Axle Shaft Assembly

from

$171.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

FAQs for 2010 Lexus IS250 Drive Shafts and Axles

What are the best-selling Drive Shafts and Axles for 2010 Lexus IS250s?

Out of 5 Drive Shafts and Axles that fit 2010 Lexus IS250s, the following parts are the top sellers:

What’s the price range for 2010 Lexus IS250 Drive Shafts and Axles?

The prices of Drive Shafts and Axles for the 2010 Lexus IS250 range from $117.99 up to $1,215.00 for the most premium parts.

What is the average price of a Drive Shafts and Axle for a 2010 Lexus IS250?

The average price for Drive Shafts and Axles for the 2010 Lexus IS250 is $479.44. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drive Shafts and Axles for other Lexus IS250 model years?

Yes, we carry Drive Shafts and Axles for 8 model years of Lexus IS250s between 2006 and 2015. The following model years are the most popular for Drive Shafts and Axle purchases: 2015, 2014, 2013, 2012, 2011, 2009, 2008, 2007, and 2006.

What are the cheapest Drive Shafts and Axles for my 2010 Lexus IS250?

The cheapest 2010 Lexus IS250 Drive Shafts and Axles we carry are:

Does Advance Auto Parts sell Drive Shafts and Axles for any other 2010 Lexus models?

Yes. We stock Drive Shafts and Axles for 11 other popular 2010 Lexus models. Some of the most popular are 2010 ES350 Drive Shafts and Axles, 2010 RX350 Drive Shafts and Axles, 2010 GX460 Drive Shafts and Axles, 2010 SC430 Drive Shafts and Axles, and 2010 IS350 Drive Shafts and Axles.

What are the top-rated Drive Shafts and Axles that fit the 2010 Lexus IS250?

The one 2010 Lexus IS250 Drive Shafts and Axle we have in stock is the CV Axle Shaft Assembly. It is rated 1 stars and costs $117.99.

What types of Drive Shafts and Axles do you sell for my 2010 Lexus IS250?

As of 6/2/26, these are some of the most in-demand types of Drive Shafts and Axles for a 2010 Lexus IS250:

Can I get help with 2010 Lexus IS250 Drive Shafts and Axle orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Drive Shafts and Axles and more.

What is your return policy for Lexus IS250 Drive Shafts and Axles?

Advance Auto Parts keeps returns simple. For new Lexus IS250 Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.