2010 Lexus HS250H Drivetrains

Essential Drivetrains for 2010 Lexus HS250Hs

National – Multi Purpose Seal (Part No.710316)

Multi Purpose Seal

from

$8.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.10114-042B)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$12.79
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.30040096-75000C)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$14.49
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

National – Shaft Repair Sleeve (Part No.99157)

Shaft Repair Sleeve

from

$37.49
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

National – Shaft Repair Sleeve (Part No.99139)

Shaft Repair Sleeve

from

$39.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

EMPI – Axle Shaft Nut (Part No.K403059357EMP)

Axle Shaft Nut

from

$5.11
The EMPI Axle Shaft Nut is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

Dorman – Spindle Nut (Part No.K1002751713DOR)

Spindle Nut

from

$17.46
Spindle Nut

National – Shaft Repair Sleeve (Part No.99166)

Shaft Repair Sleeve

from

$34.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

Beck/Arnley – Cu Boot Kit (Part No.103-2867)

Cu Boot Kit

from

$41.49
Beck/Arnley parts meet foreign nameplate OE specifications for form, fit and function. Our product specialists work with a network of global sourcing partners so you can install the right part with confidence.

Product Features:
  • Matches OE form, fit and function
  • One piece neoprene boot
  • Kit complete with boot, grease, and hardware for complete installation
  • Hardware matches original design requirements
  • Application specific for this vehicle
See More

Dorman – Spindle Nut M22-1.50 Hex Star Pattern (sold by each) (Part No.615-224)

Spindle Nut M22-1.50 Hex Star Pattern (sold by each)

from

$8.49
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

NSK – Wheel Hub Assembly (Part No.K7001321477NSK)

Wheel Hub Assembly

from

$266.96
NSK guarantees the high quality of all of their products by repeated, rigorous bench testing, and other checks that take full advantage of their cutting-edge technology, which only the major bearing manufacturers can offer. Double-row angular contact ball bearings with inner and outer mounting flange. NSK Hub unit bearings are designed to meet increasingly strict requirements that demand lighter weight, greater promotion of fuel efficiency, and enhanced module production systems. Double-row angular contact ball bearing with integral inner and outer mounting flange. Easier mounting due to preset preload.

Product Features:
  • Preset optimum preload with easy mounting process
  • High rigidity
  • Easy mounting process NSK offers compact and lightweight hub unit bearings with built-in ABS sensors
  • Integrated sensor rotor (encoder)
  • Compact size and lightweight achieved by utilizing active sensor
See More

Needa Parts – Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack (Part No.090-030)

Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack

from

$6.79
This engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles. It is engineered to replace a missing or damaged plug & help ensure a secure seal.

Product Features:
  • Direct replacement – this engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles.
  • Ideal solution – engineered to replace a missing or damaged plug and help ensure a secure seal
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

Driveworks – Camshaft Seal (Part No.S-99139)

Camshaft Seal

from

$23.99
Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710711)

Multi Purpose Seal

from

$11.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Upgrade your 2010 Lexus HS250H with Top-Quality Drivetrains

When it comes to maintaining or upgrading your 2010 Lexus HS250H, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Drivetrains are key to keeping your HS250H functioning at its best. At Advance Auto Parts, we offer a wide selection of 14 Drivetrains for the 2010 Lexus HS250H, designed to meet your needs without breaking the bank. From CV Axles and Joint replacements to Drive Shafts and Axles upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Drivetrains for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Drivetrains for your 2010 Lexus HS250H at great prices. Our Drivetrains inventory for this model ranges from just $5.11 to $266.96, with an average price of $37.88. Our 14 Drivetrains in stock come from 8 trusted brands, so you’re sure to find the right part for your 2010 Lexus HS250H without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2010 Lexus HS250H, we stock popular OEM and aftermarket Drivetrains from top names like National, and more. National Drivetrains start at just $8.79 and boast an impressive 4 stars average rating from customers. With 4 customer reviews and counting, our 2010 Lexus HS250H Drivetrains have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Drivetrain upgrades. Explore related part types like Oil and Lubricants, Fluids and Chemicals and more to make sure your 2010 Lexus HS250H is always ready to roll. We’re committed to providing you with everything you need to keep your HS250H in top shape, all in one place. Start shopping confidently below for your 2010 Lexus HS250H!

Best-Selling CV Axles and Joints for 2010 Lexus HS250Hs

Enhance the driving experience in your Lexus with 1 quality CV Axles and Joint components, starting at $41.49.

Beck/Arnley – Cu Boot Kit (Part No.103-2867)

Cu Boot Kit

from

$41.49
Beck/Arnley parts meet foreign nameplate OE specifications for form, fit and function. Our product specialists work with a network of global sourcing partners so you can install the right part with confidence.

Product Features:
  • Matches OE form, fit and function
  • One piece neoprene boot
  • Kit complete with boot, grease, and hardware for complete installation
  • Hardware matches original design requirements
  • Application specific for this vehicle
See More

Most Popular 2010 Lexus HS250H Drive Shafts and Axles

Customize your Lexus with 4 Drive Shafts and Axles products like Axle Shaft Bearings, Drive Shaft Seals, and Axle Nuts, all priced under $34.99.

National – Shaft Repair Sleeve (Part No.99166)

Shaft Repair Sleeve

from

$34.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

Dorman – Spindle Nut (Part No.K1002751713DOR)

Spindle Nut

from

$17.46
Spindle Nut

National – Multi Purpose Seal (Part No.710316)

Multi Purpose Seal

from

$8.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

EMPI – Axle Shaft Nut (Part No.K403059357EMP)

Axle Shaft Nut

from

$5.11
The EMPI Axle Shaft Nut is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

Top Picks for 2010 Lexus HS250H Differentials

Upgrade Lexus HS250Hs with top-quality Differentials parts, including 6 OEM and aftermarket selections for your 2010 model.

National – Shaft Repair Sleeve (Part No.99139)

Shaft Repair Sleeve

from

$39.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

National – Shaft Repair Sleeve (Part No.99157)

Shaft Repair Sleeve

from

$37.49
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.30040096-75000C)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$14.49
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.10114-042B)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$12.79
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Needa Parts – Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack (Part No.090-030)

Standard Engine Oil Drain Plug: 9/16-18 Thread, 0.75 " Head, 1 Pack

from

$6.79
This engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles. It is engineered to replace a missing or damaged plug & help ensure a secure seal.

Product Features:
  • Direct replacement – this engine oil drain plug is designed to match the fit and function of an original equipment plug on specified vehicles.
  • Ideal solution – engineered to replace a missing or damaged plug and help ensure a secure seal
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
See More

Driveworks – Camshaft Seal (Part No.S-99139)

Camshaft Seal

from

$23.99
Product Features:
  • Brand may vary by location
See More

In-Demand Transfer Cases for 2010 Lexus HS250Hs

Select from 1 premium Transfer Cases parts for your 2010 Lexus HS250H.

National – Multi Purpose Seal (Part No.710711)

Multi Purpose Seal

from

$11.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Most Sold 2010 Lexus HS250H Spindles

Explore our best-selling Lexus parts for the 2010 HS250H among 1 OEM and aftermarket options starting from $8.49.

Dorman – Spindle Nut M22-1.50 Hex Star Pattern (sold by each) (Part No.615-224)

Spindle Nut M22-1.50 Hex Star Pattern (sold by each)

from

$8.49
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Top-Rated Drivetrains Brands For Your 2010 Lexus HS250H

Shop for the best-rated brands offering Drivetrains and other products for your 2010 Lexus HS250Hs. Below you’ll find some of our best rated Drivetrains from National, and more. Drivetrains from these brands that fit a 2010 HS250H start at just $8.79 and are rated as high as 4 stars. OEM and aftermarket Drivetrains don’t get more top quality, durable, and affordable than from the brands below.

Popular National 2010 Lexus HS250H Drivetrains

When it comes to maintaining or upgrading your 2010 Lexus HS250H, using quality Drivetrains is essential to ensure durability and a perfect fit. National ticks all of those boxes. We offer a wide selection of National Drivetrains, specifically designed for the 2010 Lexus HS250H. With over 5 National brand Drivetrains in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $8.79, with an average price of just $26.55. Plus, with over 2 customer reviews and an average rating of 4 stars, you can trust that our National Drivetrains will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

Multi Purpose Seal
from
$11.49
This product is not rated

Multi Purpose Seal

“”

Shaft Repair Sleeve
from
$34.99
This product is not rated

Shaft Repair Sleeve

“”

Multi Purpose Seal
from
$8.79
This product is not rated

Multi Purpose Seal

“”

FAQs for 2010 Lexus HS250H Drivetrains

Which Drivetrains are best-sellers for 2010 Lexus HS250Hs?

Out of 14 Drivetrains that fit 2010 Lexus HS250Hs, the following parts are the top sellers:

What’s the price range for 2010 Lexus HS250H Drivetrains?

Drivetrain prices for the 2010 Lexus HS250H start at $5.11 and go up to $266.96 for the most premium parts.

What’s the average price of a Drivetrain for a 2010 Lexus HS250H?

The average price for Drivetrains for the 2010 Lexus HS250H is $37.88. Keep in mind the variety of part types within our Drivetrain category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drivetrains for other Lexus HS250H model years?

Yes, we currently carry Drivetrains for 2 model years of Lexus HS250Hs between 2011 and 2012. Drivetrains are bought most frequently for the following model years: 2012 and 2011.

What are the cheapest Drivetrains for my 2010 Lexus HS250H?

The cheapest 2010 Lexus HS250H Drivetrains we carry in stock are:

What are the top-rated Drivetrains that fit the 2010 Lexus HS250H?

Out of 4 reviews by customers, our 2010 Lexus HS250H Drivetrains have an average customer rating of . These are some of the highest-rated Drivetrain types for the 2010 Lexus HS250H and their top-rated products:

What types of Drivetrains do you sell for my 2010 Lexus HS250H?

As of 2/5/25, these are some of the most in-demand types of Drivetrains for a 2010 Lexus HS250H:

Can I get help with 2010 Lexus HS250H Drivetrain orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Drivetrains and more.

What is your return policy for Lexus HS250H Drivetrains?

Advance Auto Parts keeps returns simple. For new Lexus HS250H Drivetrains and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.