2010 Dodge Ram 4500 Drive Shafts and Axles

Keep Your 2010 Dodge Ram 4500 in Top Shape with Quality Drive Shafts and Axles

Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2010 Dodge Ram 4500 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Center Support Bearings, Axle Shaft Seals, and Axle Shaft Universal Joints. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Explore Related Parts

While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Hubs and Hub Assemblies and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2010 Dodge Ram 4500 in peak condition, inside and out.

Essential 2010 Dodge Ram 4500 Drive Shafts and Axles

Dorman – Center Support Bearing (Part No.934-049)

Center Support Bearing

from

$119.99
Product Features:
  • Direct replacement – this drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles
  • Restores functionality – this bearing is made to fit and fully restore part functionality after the original bearing fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-508)

Drive Shaft: Greaseable, Adjustable

from

$1846.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-520)

Drive Shaft: Greaseable, Adjustable

from

$4335.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-518)

Drive Shaft: Greaseable, Adjustable

from

$772.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-517)

Drive Shaft: Greaseable, Adjustable

from

$4383.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.938-230)

Drive Shaft: Greaseable, Adjustable

from

$1995.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-519)

Drive Shaft: Greaseable, Adjustable

from

$1333.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-510)

Drive Shaft: Greaseable, Adjustable

from

$1758.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-509)

Drive Shaft: Greaseable, Adjustable

from

$1641.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.938-169)

Drive Shaft: Greaseable, Adjustable

from

$1242.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Yukon Gear – AxleShaftSeal (Part No.30358)

AxleShaftSeal

from

$30.99
AxleShaftSeal

National – Drive Axle Shaft Seal (Part No.711046)

Drive Axle Shaft Seal

from

$39.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Spicer – Drive Axle Shaft Universal Joint (Part No.5-3212X)

Drive Axle Shaft Universal Joint

from

$76.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.
See More

Most Popular Center Support Bearing for 2010 Dodge Ram 4500s

Enhance your 2010 Dodge Ram 4500 with this popular Center Support Bearing we have in stock, for $119.99.

Dorman – Center Support Bearing (Part No.934-049)

Center Support Bearing

from

$119.99
Product Features:
  • Direct replacement – this drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles
  • Restores functionality – this bearing is made to fit and fully restore part functionality after the original bearing fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Best-Selling 2010 Dodge Ram 4500 Axle Shaft Seals

Upgrade your Ram 4500 with one of our 2 best-selling Axle Shaft Seals.

National – Drive Axle Shaft Seal (Part No.711046)

Drive Axle Shaft Seal

from

$39.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Yukon Gear – AxleShaftSeal (Part No.30358)

AxleShaftSeal

from

$30.99
AxleShaftSeal

Top-Quality Axle Shaft Universal Joints for 2010 Dodge Ram 4500s

Choose a high-quality OEM or aftermarket Axle Shaft Universal Joint for Dodge Ram 4500s and enjoy top-notch performance from $76.99.

Spicer – Drive Axle Shaft Universal Joint (Part No.5-3212X)

Drive Axle Shaft Universal Joint

from

$76.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.
See More

Top Picks for 2010 Dodge Ram 4500 Drive and Prop Shaft Assemblies

Invest in one of our 16 durable Drive and Prop Shaft Assemblies for your 2010 Dodge, knowing you’re getting trusted brands and expert craftsmanship.

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.938-169)

Drive Shaft: Greaseable, Adjustable

from

$1242.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-521)

Drive Shaft: Greaseable, Adjustable

from

$4432.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-394)

Drive Shaft: Greaseable, Adjustable

from

$4383.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-517)

Drive Shaft: Greaseable, Adjustable

from

$4383.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-520)

Drive Shaft: Greaseable, Adjustable

from

$4335.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Rear Drive Shaft: Adjustable (Part No.976-767)

Rear Drive Shaft: Adjustable

from

$2702.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.938-230)

Drive Shaft: Greaseable, Adjustable

from

$1995.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-508)

Drive Shaft: Greaseable, Adjustable

from

$1846.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-510)

Drive Shaft: Greaseable, Adjustable

from

$1758.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-509)

Drive Shaft: Greaseable, Adjustable

from

$1641.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-395)

Drive Shaft: Greaseable, Adjustable

from

$1552.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-519)

Drive Shaft: Greaseable, Adjustable

from

$1333.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-507)

Drive Shaft: Greaseable, Adjustable

from

$1329.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-396)

Drive Shaft: Greaseable, Adjustable

from

$1287.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-518)

Drive Shaft: Greaseable, Adjustable

from

$772.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Drive Shaft: Greaseable, Adjustable (Part No.946-516)

Drive Shaft: Greaseable, Adjustable

from

$701.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

FAQs for 2010 Dodge Ram 4500 Drive Shafts and Axles

What are the best-selling Drive Shafts and Axles for 2010 Dodge Ram 4500s?

Out of 20 Drive Shafts and Axles that fit 2010 Dodge Ram 4500s, the following parts are the top sellers:

What’s the price range for 2010 Dodge Ram 4500 Drive Shafts and Axles?

The prices of Drive Shafts and Axles for the 2010 Dodge Ram 4500 range from $30.99 up to $4,432.99 for the most premium parts.

What is the average price of a Drive Shafts and Axle for a 2010 Dodge Ram 4500?

The average price for Drive Shafts and Axles for the 2010 Dodge Ram 4500 is $1,798.74. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.

What are the cheapest Drive Shafts and Axles for my 2010 Dodge Ram 4500?

The cheapest 2010 Dodge Ram 4500 Drive Shafts and Axles we carry are:

Does Advance Auto Parts sell Drive Shafts and Axles for any other 2010 Dodge models?

What types of Drive Shafts and Axles do you sell for my 2010 Dodge Ram 4500?

As of 11/2/25, these are some of the most in-demand types of Drive Shafts and Axles for a 2010 Dodge Ram 4500:

Can I get help with 2010 Dodge Ram 4500 Drive Shafts and Axle orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Dodge Drive Shafts and Axles and more.

What is your return policy for Dodge Ram 4500 Drive Shafts and Axles?

Advance Auto Parts keeps returns simple. For new Dodge Ram 4500 Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.