2006 Mercedes-Benz C280 Engine Cooling Parts

Keep Your 2006 Mercedes-Benz C280 in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2006 Mercedes-Benz C280 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Thermostats, Radiators, and Water Pumps. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium, Dorman, and Motorad. For example, Carquest Premium Engine Cooling Parts start at just $19.99 with an average 4.4 star rating. Dorman and Motorad offer similar pricing and quality, backed by strong customer feedback. With over 20 reviews and a solid 5 star average, you can shop with confidence knowing other Mercedes-Benz C280 owners approve.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Air Conditioning Parts and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2006 Mercedes-Benz C280 in peak condition, inside and out.

Essential 2006 Mercedes-Benz C280 Engine Cooling Parts

Carquest Premium – New Auxiliary Water Pump (Part No.T2295)

New Auxiliary Water Pump

from

$221.99
This new pump is 100% tested to ensure the highest quality. Each unit is built to meet or exceed all OE specifications and is validated for fit, form, and function. Application specific design to ensure a perfect fit and correct operation for unsurpassed quality.

Product Features:
  • Electric water pump
  • Specialized for vehicles using supplemented cooling for the engine or components
  • Plastic housing
  • All components necessary for installation are supplied with pump
  • Follow all enclosed instructions to maximize pump life and validate warranty
See More

Carquest Premium – Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees (Part No.49382)

Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees

from

$242.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Integrated Thermostat Housing: With Seal, 192 Degrees (Part No.14569)

Integrated Thermostat Housing: With Seal, 192 Degrees

from

$49.49
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Rein – RADIATOR MOUNT (Part No.AVM0738)

RADIATOR MOUNT

from

$4.99
Anti-vibration parts dampen vibration harmonics from the engine and drive line components to rest of the vehicle. This in turn reduces vibration and noise which can be felt and heard while the vehicle is in operation. Rein Automotive anti-vibration parts are application specific and match the design and function of the OE parts.

Product Features:
  • Rubber components match the shore hardness of the original equipment bushing to ensure maximum performance and product longevity.
  • Part has a high corrosion resistance for maximum life.
  • Produced with high quality materials to ensure maximum life and a smooth ride.
  • Made by the OE manufacturer.
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MAHLE Original – Engine Coolant Thermostat Housing Gasket (Part No.C31967)

Engine Coolant Thermostat Housing Gasket

from

$3.99
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Felpro – Engine Coolant Thermostat Housing Gasket (Part No.36241)

Engine Coolant Thermostat Housing Gasket

from

$3.79
Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered for the sealing repair environment
  • Validated for fit, form and function
  • Unsurpassed quality you can trust
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Carquest Premium – Standard Reservoir Cap: 21 PSI (Part No.10253)

Standard Reservoir Cap: 21 PSI

from

$19.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Carquest Premium – Engine Electric Water Pump: New, Plastic/Steel Housing (Part No.T1244)

Engine Electric Water Pump: New, Plastic/Steel Housing

from

$245.99
Carquest Premium auxiliary water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
See More

Dorman – Auxiliary Coolant Pump (Part No.902-088)

Auxiliary Coolant Pump

from

$322.99
This engine auxiliary water pump is designed to match the fit and function of the original pump on specified applications, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this engine auxiliary water pump is designed to match the fit and function of the original pump on specified applications
  • Restores functionality – reliable replacement for an original pump that has failed to provide sufficient water flow
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Victor Reinz – Engine Coolant Thermostat Gasket (Part No.41-76159-00)

Engine Coolant Thermostat Gasket

from

$18.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Victor Reinz – Engine Coolant Thermostat Gasket (Part No.41-73174-00)

Engine Coolant Thermostat Gasket

from

$3.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Carquest Premium – Coolant Temperature Sensor 1TS1049 (Part No.WTC1122)

Coolant Temperature Sensor 1TS1049

from

$21.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
  • O-rings, seals or thread sealant are included if required
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Rein – Temperature Sensor (Part No.ELC0074)

Temperature Sensor

from

$17.99
Rein Automotive OE temperature sensors are made to factory specifications ensuring proper fit, form and function. The temperature sensor is used to report exhaust temperatures to the vehicle’s ECU. The vehicle uses this information to control engine and emission paramaters. Rein temperature sensors include a vehicle specific connector that fits directly into the factory plug. Our quality temperature sensors aim to provide the professional repair technician and vehicle owner the peace of mind and trust that is expected from an OE component.

Product Features:
  • Direct OE replacemet
  • Designed to meet or exceed factory specifications
  • Made using high quality materials
  • Uses vehicle specific style connector for quick replacement.
See More

MAHLE Original – Water Pump Gasket (Part No.K31933)

Water Pump Gasket

from

$7.99
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Victor Reinz – Engine Water Pump Gasket (Part No.71-37719-00)

Engine Water Pump Gasket

from

$7.79
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Victor Reinz – Engine Water Pump Gasket (Part No.71-37221-00)

Engine Water Pump Gasket

from

$16.79
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.432540)

Radiator: With Transmission Oil Cooler

from

$348.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.432539)

Radiator: With Transmission Oil Cooler

from

$261.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.433630)

Radiator: With Transmission Oil Cooler

from

$179.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3128)

Engine Water Pump: New, Gasket/Seals Included

from

$204.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
See More

Rein – Water Pump- Metal Impeller (Part No.WPR0017)

Water Pump- Metal Impeller

from

$149.99
Rein Automotive OE quality water pumps are designed to be direct replacements for OE water pumps and water pump assembles. Rein water pumps are made to original casting specifications to ensure proper fitments for easy installation, proper water flow and maximum cooling. Pumps include the necessary OE style gaskets and/or o-rings to replace the old worn out parts. Seals are made from a high quality silicate carbide compound. Bearings of OE design and materials are also used to meet or exceed OEM standards and ensure long service life. Our quality water pumps aim to provide the professional repair technician and vehicle owner the peace of mind and trust that is expected from an OE quality component. Please read and follow all enclosed instructions to maximize pump life and validate warranty.

Product Features:
  • Pump is produced with silicon carbide seals providing improved durability and service life
  • Pump uses OE designed bearings by ensuring to extend pumps service life
  • Read and follow all enclosed instructions to maximize pump life and to qualify for extended warranty
See More

Rein – Water Pump- Metal Impeller (Part No.WPR0018)

Water Pump- Metal Impeller

from

$126.99
Rein Automotive OE quality water pumps are designed to be direct replacements for OE water pumps and water pump assembles. Rein water pumps are made to original casting specifications to ensure proper fitments for easy installation, proper water flow and maximum cooling. Pumps include the necessary OE style gaskets and/or o-rings to replace the old worn out parts. Seals are made from a high quality silicate carbide compound. Bearings of OE design and materials are also used to meet or exceed OEM standards and ensure long service life. Our quality water pumps aim to provide the professional repair technician and vehicle owner the peace of mind and trust that is expected from an OE quality component. Please read and follow all enclosed instructions to maximize pump life and validate warranty.

Product Features:
  • Pump is produced with silicon carbide seals providing improved durability and service life
  • Pump uses OE designed bearings by ensuring to extend pumps service life
  • Read and follow all enclosed instructions to maximize pump life and to qualify for extended warranty
See More

Rein – Expansion Tank Kit (Part No.EPK0008)

Expansion Tank Kit

from

$77.99
Rein Automotive OE quality expansion tank kits, install, fit and perform the way the original manufacturer intended. These tanks are designed to match or exceed the OE materials used and are produced from virgin plastic with no regrind to prevent cracking from heat cycles and ensure the plastic is durable and will have a long service life

Product Features:
  • Includes sensor (if applicable) and Cap
  • Produced from virgin plastic meeting/exceeding OE specifications and ensuring long life
  • Resistant to cracking and wear from heat cycles preventing coolant loss
  • Direct fitment allows easy installation
See More

Rein – Expansion Tank (Part No.EPT0008)

Expansion Tank

from

$48.99
Rein Automotive OE quality expansion tanks, install, fit and perform the way the original manufacturer intended. These tanks are designed to match or exceed the OE materials used and are produced from virgin plastic with no regrind to prevent cracking from heat cycles and ensure the plastic is durable and will have a long service life.

Product Features:
  • Produced from virgin plastic meeting/exceeding OE specifications and ensuring long life
  • Resistant to cracking and wear from heat cycles preventing coolant loss
  • Direct fitment allows easy installation
  • Manufactured to strict engineering standards/specifications in materials and tolerances
See More

Rein – Expansion Tank (Part No.EPT0001)

Expansion Tank

from

$62.99
Rein Automotive OE quality expansion tanks, install, fit and perform the way the original manufacturer intended. These tanks are designed to match or exceed the OE materials used and are produced from virgin plastic with no regrind to prevent cracking from heat cycles and ensure the plastic is durable and will have a long service life.

Product Features:
  • Produced from virgin plastic meeting/exceeding OE specifications and ensuring long life
  • Resistant to cracking and wear from heat cycles preventing coolant loss
  • Direct fitment allows easy installation
  • Manufactured to strict engineering standards/specifications in materials and tolerances
See More

Carquest Premium – Standard Thermostat: 170 Degrees (Part No.248-174JV)

Standard Thermostat: 170 Degrees

from

$30.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Thermostat, 189 Degrees Fahrenheit (Part No.48019)

Thermostat, 189 Degrees Fahrenheit

from

$45.29
Original equipment design provides exact fit and performance.

Product Features:
  • Precise fitting sealing edges prevent leakage and premature cooling.
  • Self-cleaning and self-aligning thermostat valve.
  • Stainless steel assembly and springs are engineered for long life and smooth performance.
See More

URO Parts – Thermostat Assembly (Part No.2722000415)

Thermostat Assembly

from

$47.99
For European vehicles, A.P.A. manufactures the URO Parts brand of quality replacement parts, which meet or exceed OEM specifications. URO Parts components are ideal for both professional and DIY vehicle repair, and are often the exclusive aftermarket alternative to overpriced ¿Genuine¿ components. By reducing deferred maintenance with URO Parts, you will increase the bottom line of your business. With its URO Premium line, A.P.A. offers problem-solving upgraded components that are superior to failure-prone OEM parts in design and/or materials. A.P.A. is so confident in the longevity and reliability of URO Premium products. URO Parts also specializes in accurate reproduction parts for classic vehicles, including a huge variety of items that are no longer available from the dealer.
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Most Popular Thermostat for 2006 Mercedes-Benz C280s

Enhance your 2006 Mercedes-Benz C280 with this popular Thermostat we have in stock, for $47.99.

URO Parts – Thermostat Assembly (Part No.2722000415)

Thermostat Assembly

from

$47.99
For European vehicles, A.P.A. manufactures the URO Parts brand of quality replacement parts, which meet or exceed OEM specifications. URO Parts components are ideal for both professional and DIY vehicle repair, and are often the exclusive aftermarket alternative to overpriced ¿Genuine¿ components. By reducing deferred maintenance with URO Parts, you will increase the bottom line of your business. With its URO Premium line, A.P.A. offers problem-solving upgraded components that are superior to failure-prone OEM parts in design and/or materials. A.P.A. is so confident in the longevity and reliability of URO Premium products. URO Parts also specializes in accurate reproduction parts for classic vehicles, including a huge variety of items that are no longer available from the dealer.
See More

Best-Selling 2006 Mercedes-Benz C280 Radiator

Upgrade your C280 with our best-selling Radiator.

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.432540)

Radiator: With Transmission Oil Cooler

from

$348.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Top-Quality Water Pumps for 2006 Mercedes-Benz C280s

Choose a high-quality OEM or aftermarket Water Pump for Mercedes-Benz C280s and enjoy top-notch performance from $204.99.

Carquest Premium – New Water Pump (Part No.T3124)

New Water Pump

from

$265.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
See More

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3128)

Engine Water Pump: New, Gasket/Seals Included

from

$204.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
See More

Top Picks for 2006 Mercedes-Benz C280 Thermostat and Water Outlet Gaskets

Invest in one of our 3 durable Thermostat and Water Outlet Gaskets for your 2006 Mercedes-Benz, knowing you’re getting trusted brands and expert craftsmanship.

Victor Reinz – Engine Coolant Thermostat Gasket (Part No.41-76159-00)

Engine Coolant Thermostat Gasket

from

$18.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

Victor Reinz – Engine Coolant Thermostat Gasket (Part No.41-73174-00)

Engine Coolant Thermostat Gasket

from

$3.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
See More

MAHLE Original – Engine Coolant Thermostat Gasket (Part No.C31964)

Engine Coolant Thermostat Gasket

from

$1.49
MAHLE® gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Top-Rated Thermostat and Water Outlet Assemblies for 2006 Mercedes-Benz C280s

Make a smart move for your 2006 Mercedes-Benz C280 with products all priced from $117.99 to $242.99.

Motorad – Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees (Part No.668-212)

Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees

from

$117.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees (Part No.49382)

Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees

from

$242.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Dorman – Thermostat Assembly: Includes Housing, Gasket, and Sensor, 212 Degrees (Part No.902-5912)

Thermostat Assembly: Includes Housing, Gasket, and Sensor, 212 Degrees

from

$192.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
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Top-Rated Engine Cooling Part Brands For Your 2006 Mercedes-Benz C280

When it comes to finding the perfect Engine Cooling Part for your 2006 Mercedes-Benz C280, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 8 trusted brands. We carry the most popular Engine Cooling Part brands including Carquest Premium, Motorad, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.4 stars) and competitive prices, as low as $19.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2006 Mercedes-Benz C280, providing peace of mind with parts that meet or exceed OEM standards.

Popular Carquest Premium 2006 Mercedes-Benz C280 Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2006 Mercedes-Benz C280, Advance Auto Parts has exactly what you need with our selection of Carquest Premium Engine Cooling Parts. We have 2 Carquest Premium Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $19.99 and an average cost of $142.99, you’ll find the perfect Engine Cooling Part for your needs and budget. Carquest Premium Engine Cooling Parts for the 2006 Mercedes-Benz C280 come highly rated, with over 3 customer reviews and an impressive average rating of 4.4 stars. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Standard Reservoir Cap: 21 PSI
from $19.99
(1)
Standard Reservoir Cap: 21 PSI
“Works well, looks identical to OEM!”
New Water Pump
from $265.99
(2)
New Water Pump
“Wonderful after market part for my mercedes Benz. Perfect fit. Very very reasonable price”

Top-Quality Motorad 2006 Mercedes-Benz C280 Engine Cooling Parts

For those in search of a high-quality Engine Cooling Part for their 2006 Mercedes-Benz C280, Advance Auto Parts offers a great selection of Motorad Engine Cooling Parts. With 1 Motorad Engine Cooling Parts in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Engine Cooling Parts start at just $117.99, giving you a range of options to suit your budget. Backed by over 6 customer ratings and an average rating of 4.3 stars, Motorad Engine Cooling Parts provide both reliability and excellent performance. Choosing a Motorad Engine Cooling Part from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees
from $117.99
(6)
Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees
“Perfect fit. Best price plus 20% discount. Only place within 50 miles with it in stock. Very happy with transaction.”

FAQs for 2006 Mercedes-Benz C280 Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2006 Mercedes-Benz C280s?

Out of 22 Engine Cooling Parts that fit 2006 Mercedes-Benz C280s, the following parts are the top sellers:

What’s the price range for 2006 Mercedes-Benz C280 Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2006 Mercedes-Benz C280 range from $1.49 up to $348.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2006 Mercedes-Benz C280?

The average price for Engine Cooling Parts for the 2006 Mercedes-Benz C280 is $114.59. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Mercedes-Benz C280 model years?

Yes, we carry Engine Cooling Parts for 7 model years of Mercedes-Benz C280s between 1994 and 2007. The following model years are the most popular for Engine Cooling Part purchases: 2007, 2000, 1999, 1998, 1997, 1996, 1995, and 1994.

What are the cheapest Engine Cooling Parts for my 2006 Mercedes-Benz C280?

The cheapest 2006 Mercedes-Benz C280 Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2006 Mercedes-Benz models?

Yes. We stock Engine Cooling Parts for 35 other popular 2006 Mercedes-Benz models. Some of the most popular are 2006 E320 Engine Cooling Parts, 2006 SLK55 AMG Engine Cooling Parts, 2006 SL600 Engine Cooling Parts, 2006 SLK350 Engine Cooling Parts, and 2006 S600 Engine Cooling Parts.

What types of Engine Cooling Parts do you sell for my 2006 Mercedes-Benz C280?

As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2006 Mercedes-Benz C280:

Can I get help with 2006 Mercedes-Benz C280 Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Mercedes-Benz Engine Cooling Parts and more.

What is your return policy for Mercedes-Benz C280 Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Mercedes-Benz C280 Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.