2006 Isuzu I-280 Differentials

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Keep Your 2006 Isuzu I-280 in Top Shape with Quality Differentials

Whether you’re repairing or upgrading your Differential, using high-quality parts is key to keeping your 2006 Isuzu I-280 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Differential Bearings, Differential Oil, and Rear Housing Cover Gaskets. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Differentials from Trusted Brands

Looking for a reliable Differential? We’ve got you covered with options from brands you know and trust like National, Motive Gear, and Felpro. For example, National Differentials start at just $20.99 with an average 4.3 star rating. Motive Gear and Felpro offer similar pricing and quality, backed by strong customer feedback. With over 463 reviews and a solid 4 star average, you can shop with confidence knowing other Isuzu I-280 owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2006 Isuzu I-280 Differential at Advance Auto Parts is around $39.49, with a range that starts at $2.99 and goes up to $169.99. With 15 options in stock from 6 trusted brands, finding the right fit is easy. Popular picks like Tapered Roller Bearing Cone, Bearing Race, and Multi-Purpose Bearing start at just $9.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Differential, don’t forget to check out other key components like 4WD Components and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2006 Isuzu I-280 in peak condition, inside and out.

Essential 2006 Isuzu I-280 Differentials

Motive Gear – Differential Pinion Shim Kit (Part No.1100)

Differential Pinion Shim Kit

from

$7.99
High-quality Differential Component Shim

Product Features:
  • SHIM KIT FITS-8.25-F7.5-AMC20-GM0
See More

Felpro – Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket (Part No.RDS 55479)

Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket

from

$42.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Unsurpassed quality you can trust
  • Validated for fit, form and function
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

National – Multi-Purpose Seal (Part No.710474)

Multi-Purpose Seal

from

$20.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Pro-King – Differential Crush Sleeve (Part No.741A034)

Differential Crush Sleeve

from

$3.99
Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:
  • Meets or exceeds OE specifications
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Motive Gear – Differential Carrier Shim Kit (Part No.1101)

Differential Carrier Shim Kit

from

$8.99
High-quality Differential Carrier Shim Kit

Product Features:
  • CARRIER SHIMS 12 BOLT GM CAR & TRUCK ALSO GM8.6″ 99-ON
See More

Pro-King – Differential Cross Shaft (Part No.742G930)

Differential Cross Shaft

from

$2.99
Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:
  • Meets or exceeds OE specifications
See More

Motive Gear – Differential Gear Install Kit (Part No.GM8IK)

Differential Gear Install Kit

from

$56.99
Product Features:
  • MINI INSTALL KIT-GM 8″
See More

Motive Gear – Differential Master Bearing Kit – Koyo (Part No.RG8RMK)

Differential Master Bearing Kit - Koyo

from

$169.99


Product Features:
  • GM8″ MASTER BEARING & SEAL KIT
See More

Motive Gear – Differential Bearing Kit – Koyo (Part No.RG8R)

Differential Bearing Kit - Koyo

from

$165.99
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
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Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$12.49
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA

Product Features:
  • FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
  • HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
  • IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
  • ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
See More

National – Multi-Purpose Bearing (Part No.A-36)

Multi-Purpose Bearing

from

$27.99
Manufactured with premium-grade steel, National taper bearing sets feature crowned raceways and rollers to ensure even load distribution.

Product Features:
  • CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
  • PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN: Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Driveworks – Tapered Roller Bearing (Part No.S-M-802048)

Tapered Roller Bearing

from

$17.49
Product Features:
  • Brand may vary by location
See More

National – Bearing Race (Part No.M86610)

Bearing Race

from

$9.99
Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

National – Tapered Roller Bearing Cone (Part No.M802048)

Tapered Roller Bearing Cone

from

$25.99
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Most Popular Differential Bearing for 2006 Isuzu I-280s

Enhance your 2006 Isuzu I-280 with this popular Differential Bearing we have in stock, for $27.99.

National – Multi-Purpose Bearing (Part No.A-36)

Multi-Purpose Bearing

from

$27.99
Manufactured with premium-grade steel, National taper bearing sets feature crowned raceways and rollers to ensure even load distribution.

Product Features:
  • CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
  • PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN: Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Best-Selling 2006 Isuzu I-280 Differential Oil

Upgrade your I-280 with our best-selling Differential Oil with a 5 Starts rating across 446 reviews.

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$12.49
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA

Product Features:
  • FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
  • HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
  • IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
  • ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
See More

Top-Quality Rear Housing Cover Gaskets for 2006 Isuzu I-280s

Choose a high-quality OEM or aftermarket Rear Housing Cover Gasket for Isuzu I-280s and enjoy top-notch performance from $42.99.

Felpro – Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket (Part No.RDS 55479)

Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket

from

$42.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Unsurpassed quality you can trust
  • Validated for fit, form and function
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

Our Top Pick for a 2006 Isuzu I-280 Differential Pinion Seal

Invest in a durable Differential Pinion Seal for your 2006 Isuzu, knowing you’re getting trusted brands and expert craftsmanship.

National – Multi-Purpose Seal (Part No.710474)

Multi-Purpose Seal

from

$20.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Top-Rated Front Differential Pinion Bearings for 2006 Isuzu I-280s

Make a smart move for your 2006 Isuzu I-280 with products all priced from $9.99 to $25.99.

National – Tapered Roller Bearing Cone (Part No.M802048)

Tapered Roller Bearing Cone

from

$25.99
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

National – Bearing Race (Part No.M86610)

Bearing Race

from

$9.99
Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Driveworks – Tapered Roller Bearing (Part No.S-M-802048)

Tapered Roller Bearing

from

$17.49
Product Features:
  • Brand may vary by location
See More

Top-Rated Differential Brands For Your 2006 Isuzu I-280

When it comes to finding the perfect Differential for your 2006 Isuzu I-280, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 6 trusted brands. We carry the most popular Differential brands including Felpro, National, and Motive Gear, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $7.99. Purchasing a Differential from us here at Advance Auto Parts is a smart move for both you and your 2006 Isuzu I-280, providing peace of mind with parts that meet or exceed OEM standards.

Popular Felpro 2006 Isuzu I-280 Differentials

If you’re looking for a top-quality Differential for your 2006 Isuzu I-280, Advance Auto Parts has exactly what you need with our selection of Felpro Differentials. We have 1 Felpro Differentials in stock for this fitment, all known for their durability and precision fit. With prices starting at just $42.99, you’ll find the perfect Differential for your needs and budget. Felpro Differentials for the 2006 Isuzu I-280 come highly rated, with over 4 customer reviews and an impressive average rating of 4.6 stars. Choosing a Felpro Differential from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket
from $42.99
(4)
Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket
“Right part, great fit ,flimsy packing”

Top-Quality National 2006 Isuzu I-280 Differentials

For those in search of a high-quality Differential for their 2006 Isuzu I-280, Advance Auto Parts offers a great selection of National Differentials. With 3 National Differentials in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Differentials start at just $20.99, with an average price of $24.99, giving you a range of options to suit your budget. Backed by over 9 customer ratings and an average rating of 4.3 stars, National Differentials provide both reliability and excellent performance. Choosing a National Differential from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
Multi-Purpose Bearing
from $27.99
(1)
Multi-Purpose Bearing
“great price”
Multi-Purpose Seal
from $20.99
(1)
Multi-Purpose Seal
“Working great, perfect fit!!”
Tapered Roller Bearing Cone
from $25.99
(7)
Tapered Roller Bearing Cone
“Good price”

FAQs for 2006 Isuzu I-280 Differentials

What are the best-selling Differentials for 2006 Isuzu I-280s?

Out of 15 Differentials that fit 2006 Isuzu I-280s, the following parts are the top sellers:

What’s the price range for 2006 Isuzu I-280 Differentials?

The prices of Differentials for the 2006 Isuzu I-280 range from $2.99 up to $169.99 for the most premium parts.

What is the average price of a Differential for a 2006 Isuzu I-280?

The average price for Differentials for the 2006 Isuzu I-280 is $39.49. Keep in mind the variety of part types within our Differential category, where you are likely to find a wide range of prices across a variety of parts and components.

What are the cheapest Differentials for my 2006 Isuzu I-280?

The cheapest 2006 Isuzu I-280 Differentials we carry are:

Does Advance Auto Parts sell Differentials for any other 2006 Isuzu models?

Yes. We stock Differentials for 9 other popular 2006 Isuzu models. Some of the most popular are 2006 Ascender Differentials, 2006 NPR Differentials, 2006 I-350 Differentials, 2006 NPR-HD Differentials, and 2006 FTR Differentials.

What are the top-rated Differentials that fit the 2006 Isuzu I-280?

Based on 463 reviews by customers, our 2006 Isuzu I-280 Differentials have an average customer rating of 4 stars. These are the highest-rated categories of Differentials for the 2006 Isuzu I-280 and their top-rated products:

What types of Differentials do you sell for my 2006 Isuzu I-280?

As of 6/2/26, these are some of the most in-demand types of Differentials for a 2006 Isuzu I-280:

Can I get help with 2006 Isuzu I-280 Differential orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Isuzu Differentials and more.

What is your return policy for Isuzu I-280 Differentials?

Advance Auto Parts keeps returns simple. For new Isuzu I-280 Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.