2006 Isuzu I-280 Differentials

Keep Your 2006 Isuzu I-280 in Top Shape with Quality Differentials

Whether you’re repairing or upgrading your Differential, using high-quality parts is key to keeping your 2006 Isuzu I-280 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Differential Bearings, Differential Crush Sleeves, and Rear Housing Cover Gaskets. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Differentials from Trusted Brands

Looking for a reliable Differential? We’ve got you covered with options from brands you know and trust like National, FELPRO, and Motive Gear. For example, National Differentials start at just $21.99 with an average 4.3 star rating. FELPRO and Motive Gear offer similar pricing and quality, backed by strong customer feedback. With over 10 reviews and a solid 4 star average, you can shop with confidence knowing other Isuzu I-280 owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2006 Isuzu I-280 Differential at Advance Auto Parts is around $51.40, with a range that starts at $2.99 and goes up to $169.99. With 14 options in stock from 6 trusted brands, finding the right fit is easy. Popular picks like Multi-Purpose Bearing, Differential Carrier Shim Kit, and Multi-Purpose Seal start at just $8.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Differential, don’t forget to check out other key components like 4WD Components and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2006 Isuzu I-280 in peak condition, inside and out.

Essential 2006 Isuzu I-280 Differentials

Pro-King – Crush Sleeve (Part No.741A034)

Crush Sleeve

from

$3.99
Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:
  • All products are designed to meet or exceed OE quality, form, fit and funtion.
See More

FAG US – Cone (Part No.KM86649)

Cone

from

$24.29
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

National – Multi-Purpose Bearing (Part No.A-36)

Multi-Purpose Bearing

from

$27.99
Product Features:
  • CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
  • PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN: Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

National – Multi-Purpose Seal (Part No.710474)

Multi-Purpose Seal

from

$21.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Motive Gear – Differential Gear Install Kit (Part No.GM8IK)

Differential Gear Install Kit

from

$56.99
Product Features:
  • MINI INSTALL KIT-GM 8″
See More

Motive Gear – Differential Carrier Shim Kit (Part No.1101)

Differential Carrier Shim Kit

from

$8.99
High-quality Differential Carrier Shim Kit

Product Features:
  • CARRIER SHIMS 12 BOLT GM CAR & TRUCK ALSO GM8.6″ 99-ON
See More

Motive Gear – Differential Pinion Shim Kit (Part No.1100)

Differential Pinion Shim Kit

from

$7.99
High-quality Differential Component Shim

Product Features:
  • SHIM KIT FITS-8.25-F7.5-AMC20-GM0
See More

Motive Gear – Differential Bearing Kit – Timken (Part No.RG8RT)

Differential Bearing Kit - Timken

from

$150.49
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
See More

Motive Gear – Differential Bearing Kit – Koyo (Part No.RG8R)

Differential Bearing Kit - Koyo

from

$165.99
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
See More

Motive Gear – Differential Master Bearing Kit – Koyo (Part No.RG8RMK)

Differential Master Bearing Kit - Koyo

from

$169.99


Product Features:
  • GM8″ MASTER BEARING & SEAL KIT
See More

Driveworks – Tapered Roller Bearing (Part No.S-M-802048)

Tapered Roller Bearing

from

$17.49
Product Features:
  • Brand may vary by location
See More

Pro-King – Differential Cross Shaft (Part No.742G930)

Differential Cross Shaft

from

$2.99
Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:
  • All products are designed to meet or exceed OE quality, form, fit and funtion.
See More

Felpro – Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket (Part No.RDS 55479)

Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket

from

$42.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Unsurpassed quality you can trust
  • Validated for fit, form and function
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

Most Popular Differential Bearings for 2006 Isuzu I-280s

Enhance your 2006 Isuzu I-280 with one of the 2 Differential Bearings we have in stock, starting at just $24.29.

National – Multi-Purpose Bearing (Part No.A-36)

Multi-Purpose Bearing

from

$27.99
Product Features:
  • CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
  • PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN: Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

FAG US – Cone (Part No.KM86649)

Cone

from

$24.29
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

Best-Selling 2006 Isuzu I-280 Differential Crush Sleef

Upgrade your I-280 with our best-selling Differential Crush Sleef.

Pro-King – Crush Sleeve (Part No.741A034)

Crush Sleeve

from

$3.99
Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:
  • All products are designed to meet or exceed OE quality, form, fit and funtion.
See More

Top-Quality Rear Housing Cover Gaskets for 2006 Isuzu I-280s

Choose a high-quality OEM or aftermarket Rear Housing Cover Gasket for Isuzu I-280s and enjoy top-notch performance from $42.99.

Felpro – Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket (Part No.RDS 55479)

Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket

from

$42.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Unsurpassed quality you can trust
  • Validated for fit, form and function
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
See More

Top Picks for 2006 Isuzu I-280 Differential Bearing Kits

Invest in one of our 3 durable Differential Bearing Kits for your 2006 Isuzu, knowing you’re getting trusted brands and expert craftsmanship.

Motive Gear – Differential Bearing Kit – Koyo (Part No.RG8R)

Differential Bearing Kit - Koyo

from

$165.99
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
See More

Motive Gear – Differential Master Bearing Kit – Koyo (Part No.RG8RMK)

Differential Master Bearing Kit - Koyo

from

$169.99


Product Features:
  • GM8″ MASTER BEARING & SEAL KIT
See More

Motive Gear – Differential Bearing Kit – Timken (Part No.RG8RT)

Differential Bearing Kit - Timken

from

$150.49
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
See More

Our Top-Rated Differential Pinion Seals for 2006 Isuzu I-280s

Make a smart move for your 2006 Isuzu I-280 with our Differential Pinion Seal for $21.99.

National – Multi-Purpose Seal (Part No.710474)

Multi-Purpose Seal

from

$21.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Top-Rated Differential Brands For Your 2006 Isuzu I-280

When it comes to finding the perfect Differential for your 2006 Isuzu I-280, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 6 trusted brands. We carry the most popular Differential brands including FELPRO, National, and Motive Gear, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $7.99. Purchasing a Differential from us here at Advance Auto Parts is a smart move for both you and your 2006 Isuzu I-280, providing peace of mind with parts that meet or exceed OEM standards.

Popular FELPRO 2006 Isuzu I-280 Differentials

If you’re looking for a top-quality Differential for your 2006 Isuzu I-280, Advance Auto Parts has exactly what you need with our selection of FELPRO Differentials. We have 1 FELPRO Differentials in stock for this fitment, all known for their durability and precision fit. With prices starting at just $42.99, you’ll find the perfect Differential for your needs and budget. FELPRO Differentials for the 2006 Isuzu I-280 come highly rated, with over 4 customer reviews and an impressive average rating of 4.6 stars. Choosing a FELPRO Differential from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket
from $42.99
(4)
Axle Housing Cover Gasket Irregular Shaped 10 Bolt Hole Gasket
“Right part, great fit ,flimsy packing”

Top-Quality National 2006 Isuzu I-280 Differentials

For those in search of a high-quality Differential for their 2006 Isuzu I-280, Advance Auto Parts offers a great selection of National Differentials. With 2 National Differentials in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Differentials start at just $21.99, with an average price of $24.99, giving you a range of options to suit your budget. Backed by over 2 customer ratings and an average rating of 4.3 stars, National Differentials provide both reliability and excellent performance. Choosing a National Differential from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
Multi-Purpose Bearing
from $27.99
(1)
Multi-Purpose Bearing
“great price”
Multi-Purpose Seal
from $21.99
(1)
Multi-Purpose Seal
“Working great, perfect fit!!”

FAQs for 2006 Isuzu I-280 Differentials

What are the best-selling Differentials for 2006 Isuzu I-280s?

Out of 14 Differentials that fit 2006 Isuzu I-280s, the following parts are the top sellers:

What’s the price range for 2006 Isuzu I-280 Differentials?

The prices of Differentials for the 2006 Isuzu I-280 range from $2.99 up to $169.99 for the most premium parts.

What is the average price of a Differential for a 2006 Isuzu I-280?

The average price for Differentials for the 2006 Isuzu I-280 is $51.40. Keep in mind the variety of part types within our Differential category, where you are likely to find a wide range of prices across a variety of parts and components.

What are the cheapest Differentials for my 2006 Isuzu I-280?

The cheapest 2006 Isuzu I-280 Differentials we carry are:

Does Advance Auto Parts sell Differentials for any other 2006 Isuzu models?

Yes. We stock Differentials for 7 other popular 2006 Isuzu models. Some of the most popular are 2006 Ascender Differentials, 2006 NPR Differentials, 2006 I-350 Differentials, 2006 NPR-HD Differentials, and 2006 FTR Differentials.

What are the top-rated Differentials that fit the 2006 Isuzu I-280?

Based on 10 reviews by customers, our 2006 Isuzu I-280 Differentials have an average customer rating of 4 stars. These are the highest-rated categories of Differentials for the 2006 Isuzu I-280 and their top-rated products:

What types of Differentials do you sell for my 2006 Isuzu I-280?

As of 11/2/25, these are some of the most in-demand types of Differentials for a 2006 Isuzu I-280:

Can I get help with 2006 Isuzu I-280 Differential orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Isuzu Differentials and more.

What is your return policy for Isuzu I-280 Differentials?

Advance Auto Parts keeps returns simple. For new Isuzu I-280 Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.