2006 GMC C4500 Topkick Engine Cooling Parts

Essential 2006 GMC C4500 Topkick Engine Cooling Parts

Carquest Premium – Standard Thermostat: With Seal, 195 Degrees (Part No.13899)

Standard Thermostat: With Seal, 195 Degrees

from

$7.29
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Standard Thermostat: With Seals, 180, 185 Degrees (Part No.447448)

Standard Thermostat: With Seals, 180, 185 Degrees

from

$40.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Imperial – Electric Fan – 14" Diameter (Part No.226114)

Electric Fan - 14" Diameter

from

$99.99
Product Features:
  • Motors built and tested to quality specifications
  • 14 in. universal fit reversible fan
  • 1250 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
See More

Carquest Premium – Radiator: With Engine And Transmission Oil Coolers (Part No.867212)

Radiator: With Engine And Transmission Oil Coolers

from

$999.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle’s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
See More

Carquest Premium – Engine Cooling Fan Module (Part No.ACC1313)

Engine Cooling Fan Module

from

$94.99
All modern vehicles consist of several independent operating systems controlled by a main system processor with independent sub-processors. The sub-processors provide class 2 serial information data to the main processor while handling the operation of the system and carry the circuit load to protect the main operating system. When replacing any level processor programming may be needed to enter the unit into the vehicles main operating system.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
See More

Imperial – Thermostatic Fan Control – Adjustable (Part No.226208)

Thermostatic Fan Control - Adjustable

from

$62.99
Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Adjustable thermostatic fan control
  • 160°F – 210°F thread-in probe
  • For use with Imperial electric fans
  • Thread-in probe for installation in water jacket or radiator
See More

Imperial – Thermostatic Fan Control – Preset (Part No.226206)

Thermostatic Fan Control - Preset

from

$38.49
Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Preset thermostatic fan control
  • 185°F preset
  • For use with Imperial electric fans
  • Probe installs into radiator fins
See More

Dorman – HD Solutions – Heavy Duty Pressurized Coolant Reservoir (Part No.603-5601)

Heavy Duty Pressurized Coolant Reservoir

from

$111.99
This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part.

Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part
  • Ideal solution – engineered for a seamless installation
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
See More

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T5096)

Engine Water Pump: New, Gasket/Seals Included

from

$162.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
See More

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T2249)

Engine Water Pump: New, Gasket/Seals Included

from

$102.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
See More

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T2284)

Engine Water Pump: New, Gasket/Seals Included

from

$167.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
See More

Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.620-619)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

from

$134.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
See More

Dorman – Coolant Housing/Water Outlet: With Water Outlet, 90 Degree Neck Angle (Part No.902-2127)

Coolant Housing/Water Outlet: With Water Outlet, 90 Degree Neck Angle

from

$111.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
See More

Dorman – Coolant Housing/Water Outlet: With Housing and Gasket, 180 Degree Neck Angle (Part No.902-2060)

Coolant Housing/Water Outlet: With Housing and Gasket, 180 Degree Neck Angle

from

$26.49
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
See More

Dorman – Coolant Housing/Water Outlet: With Housing and Gasket (Part No.902-2068)

Coolant Housing/Water Outlet: With Housing and Gasket

from

$40.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
See More

Dorman – HD Solutions – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.902-5601)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$23.79
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
See More

Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.82597)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$15.49
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
See More

Carquest Premium – Radiator Cap: 15 PSI (Part No.10248)

Radiator Cap: 15 PSI

from

$14.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Dorman – Coolant Bypass Tube O-Ring Kit (Part No.926-424)

Coolant Bypass Tube O-Ring Kit

from

$19.29
This coolant O-ring kit contains all the necessary O-rings to replace or repair the engine coolant pipe on specified vehicles.

Product Features:
  • Ideal replacement – this coolant O-ring kit matches the factory O-rings to ensure a complete and reliable repair
  • Durable construction – made of quality materials for leak-free service
  • Complete solution – includes all O-rings required to repair or replace specified coolant pipe
  • Quality tested – this part has undergone try-on and material testing to ensure a quality fit and long service life
See More

Carquest Premium – Universal Reverse Rotation Severe Duty Thermal Fan Clutch (Part No.216035)

Universal Reverse Rotation Severe Duty Thermal Fan Clutch

from

$115.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
See More

Carquest Premium – Universal Thermal Fan Clutches (Part No.216049)

Universal Thermal Fan Clutches

from

$121.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
See More

Carquest Premium – Universal Fan Clutch (Part No.216093)

Universal Fan Clutch

from

$458.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
See More

2006 GMC C4500 Topkick Engine Cooling Parts

Maybe you’re in the middle of a full rebuild of that 2006 GMC C4500 Topkick. Maybe you just need a couple of Engine Cooling Parts. Either way, Advance Auto Parts has 24 different Engine Cooling Parts in our inventory ranging from $7.29 to $999.99. That means you can find the exact parts or products you need to keep that 2006 GMC C4500 Topkick running smoothly.

Engine Cooling Parts are only as good as their brand. We stock 5 different brands to make sure you have plenty of trusted parts to choose from for your 2006 GMC C4500 Topkick. Carquest Premium, Imperial, and Motorad are just some of the brands we stock. Search for brands you know or compare prices and reviews to help you decide!

We know you’ll find the perfect Engine Cooling Parts for your 2006 GMC C4500 Topkick, but don’t take our word for it – read our customer ratings and reviews and buy with confidence. Out of the 3,339 reviews in this category, some of the top rated parts include Adjustable Thermostatic Fan Control with 3.4 stars and Electric Fan – 14" Diameter with 3.5 stars.

So if you’re in the market for aftermarket Engine Cooling Parts to keep your 2006 GMC C4500 Topkick rolling for years to come, look no further. Shop online and have your products shipped direct to your door, or pick up at the nearest Advance Auto Parts location today!

Engine Cooling Parts Brands To Make Your 2006 GMC C4500 Topkick Last

Simple repair, complete replacement, or a full rebuild. No matter the job, your 2006 GMC C4500 Topkick demands trusted brand parts and products to keep it running. Many trusted brands of Engine Cooling Parts make up Advance Auto Parts’ inventory, and all are ready to help make your C4500 Topkick the best it can be. Be sure to browse some of our top Engine Cooling Parts brands and parts.

FAQs for 2006 GMC C4500 Topkick Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the 2006 GMC C4500 Topkick?

Out of 24 Engine Cooling Parts for the 2006 GMC C4500 Topkick, the most popular in our inventory are:
Thermostat: With Seal, 195 Degrees
from $16.79
This product is not rated
Thermostat: With Seal, 195 Degrees
Thermostats
Adjustable Thermostatic Fan Control
from $22.99
(35)
Adjustable Thermostatic Fan Control
Engine Cooling Fan Controllers

What are the top-rated 2006 GMC C4500 Topkick Engine Cooling Parts?

Top-rated Engine Cooling Parts for your 2006 GMC C4500 Topkick based on customer reviews/ratings are:
Adjustable Thermostatic Fan Control
from $55.99
(33)
Adjustable Thermostatic Fan Control
“If you read the instructions it’s pretty self explanatory.”
Electric Fan - 14" Diameter
from $99.99
(14)
Electric Fan – 14" Diameter
“Fit fine. Easy install. Cools the car.”
Thermostatic Fan Control - Preset
from $38.49
(8)
Thermostatic Fan Control – Preset
“great value. easy to use”