2006 GMC C4500 Topkick Differentials

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Keep Your 2006 GMC C4500 Topkick in Top Shape with Quality Differentials

Whether you’re repairing or upgrading your Differential, using high-quality parts is key to keeping your 2006 GMC C4500 Topkick looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Differential Covers, Differential Bearings, and Differential Gear Install Kits. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Explore Related Parts

While you’re upgrading or replacing your Differential, don’t forget to check out other key components like Drive Shafts and Axles and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2006 GMC C4500 Topkick in peak condition, inside and out.

Essential 2006 GMC C4500 Topkick Differentials

Motive Gear – Differential Carrier Gear Kit (Part No.707280XR)

Differential Carrier Gear Kit

from

$172.99
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both on and off-road, check out Motive Gear. Motive Gear products can be found in the winner’s circle at racing events worldwide. The superior quality of Motive Gear components is the result of years of racing development, outstanding design and state-of-the-art manufacturing methods. Extensive testing is performed on all products by our in-house engineers.
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Schaeffler – Cup (Part No.LM48510)

Cup

from

$6.99
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
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Schaeffler – Bearing – TRB (Tapered Roller Bearing) (Part No.KT5)

Bearing - TRB (Tapered Roller Bearing)

from

$14.99
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

National – Tapered Roller Bearing Cone (Part No.25590)

Tapered Roller Bearing Cone

from

$27.99
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
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Motive Gear – Differential Ring and Pinion (Part No.D80-488)

Differential Ring and Pinion

from

$366.99


Product Features:
  • DANA-80 R/P 4.88 STD MG
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Motive Gear – Differential Gear Install Kit (Part No.D80IK)

Differential Gear Install Kit

from

$143.99


Product Features:
  • MINI INSTALL KIT DANA 80
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Most Popular Differential Cover for 2006 GMC C4500 Topkicks

Enhance your 2006 GMC C4500 Topkick with this popular Differential Cover we have in stock, for $127.99.

Spicer – Differential Cover; Dana 80; Stamped Steel (Part No.707231X)

Differential Cover; Dana 80; Stamped Steel

from

$127.99
Demand genuine Spicer. Dana design, engineering, testing and manufacturing processes all work in conjunction with one another to ensure unparalleled performance that non-genuine parts simply cannot deliver.

Product Features:
  • Genuine OE quality. Tested and proven.
  • Built to meet OE standards set by Dana.
  • Tested and validated to rigorous OE specifications.
  • Latest production upgrades ensure genuine Spicer parts are as good or better than the OE parts they replace.
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Best-Selling 2006 GMC C4500 Topkick Differential Bearings

Upgrade your C4500 Topkick with one of our 3 best-selling Differential Bearings.

National – Tapered Roller Bearing Cone (Part No.25590)

Tapered Roller Bearing Cone

from

$27.99
Manufactured with premium-grade steel, National taper bearing cones feature crowned raceways and rollers to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways and rollers for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Schaeffler – Bearing – TRB (Tapered Roller Bearing) (Part No.KT5)

Bearing - TRB (Tapered Roller Bearing)

from

$14.99
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

Schaeffler – Cup (Part No.LM48510)

Cup

from

$6.99
With advanced load-carrying capacity and compact design, tapered roller bearings are used in wheel bearings, transmissions, differentials, transfer cases and other miscellanous applications. FAG manufacturers over 100 million tapered roller bearings annually.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

Top-Quality Differential Gear Install Kits for 2006 GMC C4500 Topkicks

Choose a high-quality OEM or aftermarket Differential Gear Install Kit for GMC C4500 Topkicks and enjoy top-notch performance from $143.99.

Motive Gear – Differential Gear Install Kit (Part No.D80IK)

Differential Gear Install Kit

from

$143.99


Product Features:
  • MINI INSTALL KIT DANA 80
See More

Our Top Pick for a 2006 GMC C4500 Topkick Rear Differential Cover Gasket

Invest in a durable Rear Differential Cover Gasket for your 2006 GMC, knowing you’re getting trusted brands and expert craftsmanship.

Spicer – Performance Differential Gasket – Dana 80 (Part No.RD51997)

Performance Differential Gasket - Dana 80

from

$30.99
Spicer performance differential cover gaskets offer all-makes coverage for street, strip, drag, and off-road applications. These gaskets are reusable offering a clean release during replacement. Built with a mechanically and chemically bonder woven steel.

Product Features:
  • Made to adhere without messy RTV sealant This saves on install time by eliminating the time needed for RTV cure.
  • Provides no re-torque design with maximum compression and sealing.
  • Manufactured with proprietary high-density performance material.
  • Made in the USA.
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Our Differential Carrier Shim Kits for 2006 GMC C4500 Topkicks

Make a smart move for your 2006 GMC C4500 Topkick with our Differential Carrier Shim Kit for $172.99.

Motive Gear – Differential Carrier Gear Kit (Part No.707280XR)

Differential Carrier Gear Kit

from

$172.99
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both on and off-road, check out Motive Gear. Motive Gear products can be found in the winner’s circle at racing events worldwide. The superior quality of Motive Gear components is the result of years of racing development, outstanding design and state-of-the-art manufacturing methods. Extensive testing is performed on all products by our in-house engineers.
See More

FAQs for 2006 GMC C4500 Topkick Differentials

What are the best-selling Differentials for 2006 GMC C4500 Topkicks?

Out of 9 Differentials that fit 2006 GMC C4500 Topkicks, the following parts are the top sellers:

What’s the price range for 2006 GMC C4500 Topkick Differentials?

The prices of Differentials for the 2006 GMC C4500 Topkick range from $6.99 up to $366.99 for the most premium parts.

What is the average price of a Differential for a 2006 GMC C4500 Topkick?

The average price for Differentials for the 2006 GMC C4500 Topkick is $100.88. Keep in mind the variety of part types within our Differential category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Differentials for other GMC C4500 Topkick model years?

Yes, we carry Differentials for 5 model years of GMC C4500 Topkicks between 2003 and 2009. The following model years are the most popular for Differential purchases: 2009, 2008, 2007, 2005, 2004, and 2003.

What are the cheapest Differentials for my 2006 GMC C4500 Topkick?

The cheapest 2006 GMC C4500 Topkick Differentials we carry are:

Does Advance Auto Parts sell Differentials for any other 2006 GMC models?

Yes. We stock Differentials for 16 other popular 2006 GMC models. Some of the most popular are 2006 Yukon Differentials, 2006 Sierra 1500 Differentials, 2006 Yukon XL 1500 Differentials, 2006 Sierra 2500 HD Differentials, and 2006 Yukon XL 2500 Differentials.

What types of Differentials do you sell for my 2006 GMC C4500 Topkick?

As of 6/2/26, these are some of the most in-demand types of Differentials for a 2006 GMC C4500 Topkick:

Can I get help with 2006 GMC C4500 Topkick Differential orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about GMC Differentials and more.

What is your return policy for GMC C4500 Topkick Differentials?

Advance Auto Parts keeps returns simple. For new GMC C4500 Topkick Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.